DE3863191D1 - Substituierte aminderivate, ihre herstellung und verwendung. - Google Patents

Substituierte aminderivate, ihre herstellung und verwendung.

Info

Publication number
DE3863191D1
DE3863191D1 DE8888300596T DE3863191T DE3863191D1 DE 3863191 D1 DE3863191 D1 DE 3863191D1 DE 8888300596 T DE8888300596 T DE 8888300596T DE 3863191 T DE3863191 T DE 3863191T DE 3863191 D1 DE3863191 D1 DE 3863191D1
Authority
DE
Germany
Prior art keywords
production
substituted amine
amine derivatives
derivatives
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8888300596T
Other languages
English (en)
Inventor
Susumu Tsushima
Muneo Takatani
Minoru Hirata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of DE3863191D1 publication Critical patent/DE3863191D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
    • C07C275/06—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton
    • C07C275/14—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
DE8888300596T 1987-02-06 1988-01-26 Substituierte aminderivate, ihre herstellung und verwendung. Expired - Fee Related DE3863191D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2681687 1987-02-06
JP32251087 1987-12-18
JP62331568A JPH0761992B2 (ja) 1987-02-06 1987-12-25 置換アミン誘導体

Publications (1)

Publication Number Publication Date
DE3863191D1 true DE3863191D1 (de) 1991-07-18

Family

ID=27285549

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888300596T Expired - Fee Related DE3863191D1 (de) 1987-02-06 1988-01-26 Substituierte aminderivate, ihre herstellung und verwendung.

Country Status (13)

Country Link
US (1) US4987130A (de)
EP (1) EP0278621B1 (de)
JP (1) JPH0761992B2 (de)
AU (1) AU607180B2 (de)
CA (1) CA1327969C (de)
DE (1) DE3863191D1 (de)
DK (1) DK45188A (de)
ES (1) ES2029879T3 (de)
FI (1) FI89907C (de)
GR (1) GR3002298T3 (de)
HU (1) HU201907B (de)
IL (1) IL85183A0 (de)
NO (1) NO167734C (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5075099A (en) * 1988-05-31 1991-12-24 Neorx Corporation Metal radionuclide chelating compounds for improved chelation kinetics
US5244915A (en) * 1990-08-31 1993-09-14 Warner-Lambert Company Amico acid derivatives cyclized at the c-terminal
EP0474411A1 (de) * 1990-09-03 1992-03-11 Takeda Chemical Industries, Ltd. Herstellung von Diethanolaminderivaten und ihre Zwischenprodukte
KR100361933B1 (ko) * 1993-09-08 2003-02-14 라 졸라 파마슈티칼 컴파니 화학적으로정의된비중합성결합가플랫폼분자및그것의콘주게이트
US6458953B1 (en) 1998-12-09 2002-10-01 La Jolla Pharmaceutical Company Valency platform molecules comprising carbamate linkages
CN1333746A (zh) * 1998-12-09 2002-01-30 拉卓拉药物公司 用作包含氨基甲酸酯键的模版的分子台架
GB9907895D0 (en) * 1999-04-08 1999-06-02 Texas A & M Univ Sys Novel ligands for chiral catalysis
US6472533B1 (en) 1999-04-08 2002-10-29 The Texas A & M University System Ligands for chiral catalysis
AU2001268228A1 (en) * 2000-06-08 2001-12-17 La Jolla Pharmaceutical Company Multivalent platform molecules comprising high molecular weight polyethylene oxide
JP4882146B2 (ja) * 2000-11-09 2012-02-22 Ｊｎｃ株式会社 イミド化合物、これを含有する樹脂組成物、液晶配向膜、液晶組成物および液晶表示素子
CN113773229B (zh) * 2021-09-03 2022-10-25 西安交通大学 α,β-不饱和氨基酸衍生物及其DL-硒-甲基硒代氨基酸衍生物、合成方法和应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE949947C (de) * 1953-03-04 1956-09-27 Hoechst Ag Verfahren zur Herstellung von basischen Bis-N-phenylurethanen
CH361567A (fr) * 1959-06-11 1962-04-30 Carter Prod Inc Procédé de préparation de dicarbamates
US3285960A (en) * 1964-01-14 1966-11-15 Cutter Lab 4, 4-diphenylcyclohexylamine derivatives
CH496675A (fr) * 1968-10-29 1970-09-30 Lepetit Spa Procédé de préparation de dérivés d'acide carbamique
GB1369250A (en) * 1970-08-07 1974-10-02 Pfizer Amines the preparation thereof and their use in pharmacejtical compositions
NZ215753A (en) * 1985-04-16 1989-10-27 Hoffmann La Roche Phenethanolamine derivatives and pharmaceutical compositions

Also Published As

Publication number Publication date
DK45188A (da) 1988-08-07
NO880511L (no) 1988-08-08
EP0278621B1 (de) 1991-06-12
HUT45968A (en) 1988-09-28
AU1136088A (en) 1988-08-11
DK45188D0 (da) 1988-01-29
EP0278621A1 (de) 1988-08-17
NO167734B (no) 1991-08-26
FI880525A (fi) 1988-08-07
FI89907C (fi) 1993-12-10
HU201907B (en) 1991-01-28
GR3002298T3 (en) 1992-12-30
CA1327969C (en) 1994-03-22
NO880511D0 (no) 1988-02-05
FI89907B (fi) 1993-08-31
US4987130A (en) 1991-01-22
NO167734C (no) 1991-12-04
IL85183A0 (en) 1988-07-31
JPH0222259A (ja) 1990-01-25
JPH0761992B2 (ja) 1995-07-05
ES2029879T3 (es) 1992-10-01
AU607180B2 (en) 1991-02-28
FI880525A0 (fi) 1988-02-05

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee