AR081040A1 - Diferenciacion de celulas madre embrionarias humanas - Google Patents

Diferenciacion de celulas madre embrionarias humanas

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Publication number
AR081040A1
AR081040A1 ARP110101645A ARP110101645A AR081040A1 AR 081040 A1 AR081040 A1 AR 081040A1 AR P110101645 A ARP110101645 A AR P110101645A AR P110101645 A ARP110101645 A AR P110101645A AR 081040 A1 AR081040 A1 AR 081040A1
Authority
AR
Argentina
Prior art keywords
cells
differentiation
population
embryous
human
Prior art date
Application number
ARP110101645A
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English (en)
Original Assignee
Centocor Ortho Biotech Inc
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44912123&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR081040(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Centocor Ortho Biotech Inc filed Critical Centocor Ortho Biotech Inc
Publication of AR081040A1 publication Critical patent/AR081040A1/es

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0613—Cells from endocrine organs
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
    • C12N5/0678—Stem cells; Progenitor cells; Precursor cells
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
    • A61K35/545—Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
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    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/385—Hormones with nuclear receptors of the family of the retinoic acid recptor, e.g. RAR, RXR; Peroxisome proliferator-activated receptor [PPAR]
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells

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  • Animal Behavior & Ethology (AREA)
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Abstract

La presente proporciona métodos para promover la diferenciacion de células madre pluripotentes en células que producen insulina. Particularmente, la presente presenta un método para producir una poblacion de células que expresan marcadores característicos del linaje del endodermo pancreático, en donde más del 50 % de las células en la poblacion coexpresan PDX1 y NKX6.1. Reivindicacion 1: Una poblacion de células que expresan marcadores característicos del linaje del endodermo pancreático, en donde más del 50 % de las células en la poblacion coexpresan PDX1 y NKX6.1.
ARP110101645A 2010-05-12 2011-05-12 Diferenciacion de celulas madre embrionarias humanas AR081040A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33383110P 2010-05-12 2010-05-12

Publications (1)

Publication Number Publication Date
AR081040A1 true AR081040A1 (es) 2012-05-30

Family

ID=44912123

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP110101645A AR081040A1 (es) 2010-05-12 2011-05-12 Diferenciacion de celulas madre embrionarias humanas

Country Status (17)

Country Link
US (2) US9752125B2 (es)
EP (2) EP3498825A1 (es)
JP (4) JP6050225B2 (es)
KR (2) KR101903562B1 (es)
CN (2) CN107338217B (es)
AR (1) AR081040A1 (es)
AU (1) AU2011250912A1 (es)
BR (1) BR112012028855A2 (es)
CA (1) CA2800610C (es)
DK (1) DK2569419T3 (es)
ES (1) ES2728900T3 (es)
MX (1) MX351515B (es)
PH (1) PH12018500672A1 (es)
RU (2) RU2663339C1 (es)
SG (2) SG10201503652WA (es)
WO (1) WO2011143299A2 (es)
ZA (1) ZA201209383B (es)

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