AR061400A1 - Agentes para suprimir el dano a los islotes transplantados despues del transplante de islotes - Google Patents
Agentes para suprimir el dano a los islotes transplantados despues del transplante de islotesInfo
- Publication number
- AR061400A1 AR061400A1 ARP060104507A ARP060104507A AR061400A1 AR 061400 A1 AR061400 A1 AR 061400A1 AR P060104507 A ARP060104507 A AR P060104507A AR P060104507 A ARP060104507 A AR P060104507A AR 061400 A1 AR061400 A1 AR 061400A1
- Authority
- AR
- Argentina
- Prior art keywords
- transplanted
- inhibitor
- transplant
- agents
- islots
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Obesity (AREA)
- Rheumatology (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Surgery (AREA)
- Transplantation (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Endocrinology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Reivindicacion 1: Un agente para suprimir el dano a los islotes transplantados después del transplante de islotes, caracterizado porque comprende un inhibidor de IL-6 como ingrediente activo. Reivindicacion 2: El agente para suprimir el dano a los islotes transplantados de la reivindicacion 1, caracterizado porque el inhibidor de IL-6 es un anticuerpo que reconoce una IL-6. Reivindicacion 9: Un método para suprimir el dano a los islotes transplantados en un sujeto sometido a un transplante de islotes, caracterizado porque comprende el paso de administrarle un inhibidor de IL-6 al sujeto. Reivindicacion 10: Un método para mejorar la viabilidad de un transplante de islotes en un sujeto, caracterizado porque comprende el paso de administrarle un inhibidor de IL-6 al sujeto. Reivindicacion 17: El uso de un inhibidor de IL-6, caracterizado porque es para producir agentes para suprimir el dano a los islotes transplantados después del transplante de islotes.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2005300489 | 2005-10-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR061400A1 true AR061400A1 (es) | 2008-08-27 |
Family
ID=37942862
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP060104507A AR061400A1 (es) | 2005-10-14 | 2006-10-13 | Agentes para suprimir el dano a los islotes transplantados despues del transplante de islotes |
Country Status (15)
Country | Link |
---|---|
US (1) | US8470316B2 (es) |
EP (1) | EP1941907B1 (es) |
JP (1) | JP5014143B2 (es) |
KR (1) | KR101343190B1 (es) |
CN (1) | CN101330929B (es) |
AR (1) | AR061400A1 (es) |
AU (1) | AU2006300234B2 (es) |
BR (1) | BRPI0617378B8 (es) |
CA (1) | CA2625773C (es) |
HK (1) | HK1124533A1 (es) |
IL (1) | IL190693A (es) |
NO (1) | NO20082194L (es) |
RU (1) | RU2446826C2 (es) |
WO (1) | WO2007043641A1 (es) |
ZA (1) | ZA200803973B (es) |
Families Citing this family (50)
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UA80091C2 (en) | 2001-04-02 | 2007-08-27 | Chugai Pharmaceutical Co Ltd | Remedies for infant chronic arthritis-relating diseases and still's disease which contain an interleukin-6 (il-6) antagonist |
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AU2006300234B2 (en) | 2005-10-14 | 2013-01-10 | Chugai Seiyaku Kabushiki Kaisha | Agents for suppressing damage to transplanted islets after islet transplantation |
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TW200803894A (en) * | 2005-11-25 | 2008-01-16 | Univ Keio | Prostate cancer therapeutic agents |
US8771686B2 (en) | 2006-01-27 | 2014-07-08 | Chugai Seiyaku Kabushiki Kaisha | Methods for treating a disease involving choroidal neovascularization by administering an IL-6 receptor antibody |
EP4218801A3 (en) | 2006-03-31 | 2023-08-23 | Chugai Seiyaku Kabushiki Kaisha | Antibody modification method for purifying bispecific antibody |
EP2006381B1 (en) | 2006-03-31 | 2016-02-03 | Chugai Seiyaku Kabushiki Kaisha | Method for controlling blood pharmacokinetics of antibodies |
WO2007116962A1 (ja) * | 2006-04-07 | 2007-10-18 | Osaka University | 筋再生促進剤 |
MX2009007830A (es) * | 2007-01-23 | 2009-10-07 | Univ Shinshu | Inhibidor de rechazo cronico. |
WO2008135419A2 (en) * | 2007-05-04 | 2008-11-13 | Charité Universitätsmedizin Berlin | Anti-il-6-agents for improving primary functioning of allogenic grafts |
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TWI440469B (zh) | 2008-09-26 | 2014-06-11 | Chugai Pharmaceutical Co Ltd | Improved antibody molecules |
JP5717624B2 (ja) | 2009-03-19 | 2015-05-13 | 中外製薬株式会社 | 抗体定常領域改変体 |
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US9539322B2 (en) | 2010-05-28 | 2017-01-10 | National University Corporation Hokkaido University | Method of enhancing an antitumor T cell response by administering an anti-IL-6 receptor antibody |
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US20140234340A1 (en) | 2010-11-30 | 2014-08-21 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule capable of binding to plurality of antigen molecules repeatedly |
JP2014161257A (ja) * | 2013-02-22 | 2014-09-08 | Univ Of Tokyo | 多能性幹細胞から膵ランゲルハンス島を製造する方法 |
US10782290B2 (en) | 2013-06-11 | 2020-09-22 | National Center Of Neurology And Psychiatry | Method for predicting post-therapy prognosis of relapsing-remitting multiple sclerosis (RRMS) patient, and method for determining applicability of novel therapy |
CA2913687C (en) | 2013-07-04 | 2022-12-13 | F. Hoffmann-La Roche Ag | Interference-suppressed immunoassay to detect anti-drug antibodies in serum samples |
US9550828B2 (en) | 2013-09-05 | 2017-01-24 | Boise State University | Oncostatin M (OSM) antagonists for preventing cancer metastasis and IL-6 related disorders |
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- 2006-10-13 BR BRPI0617378A patent/BRPI0617378B8/pt active IP Right Grant
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- 2006-10-13 CN CN200680047109.4A patent/CN101330929B/zh active Active
- 2006-10-13 CA CA2625773A patent/CA2625773C/en active Active
- 2006-10-13 JP JP2007539996A patent/JP5014143B2/ja active Active
- 2006-10-13 US US12/090,061 patent/US8470316B2/en active Active
- 2006-10-13 EP EP06811729.0A patent/EP1941907B1/en active Active
- 2006-10-13 RU RU2008118906/15A patent/RU2446826C2/ru not_active IP Right Cessation
- 2006-10-13 WO PCT/JP2006/320441 patent/WO2007043641A1/ja active Application Filing
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- 2008-05-13 KR KR1020087011381A patent/KR101343190B1/ko active IP Right Grant
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Also Published As
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EP1941907A4 (en) | 2010-01-20 |
NO20082194L (no) | 2008-07-11 |
CA2625773C (en) | 2015-05-12 |
HK1124533A1 (en) | 2009-07-17 |
BRPI0617378A2 (pt) | 2011-07-26 |
EP1941907A1 (en) | 2008-07-09 |
ZA200803973B (en) | 2009-03-25 |
BRPI0617378B1 (pt) | 2021-08-10 |
RU2446826C2 (ru) | 2012-04-10 |
AU2006300234A1 (en) | 2007-04-19 |
US8470316B2 (en) | 2013-06-25 |
US20090220499A1 (en) | 2009-09-03 |
CN101330929B (zh) | 2014-03-05 |
KR101343190B1 (ko) | 2013-12-19 |
RU2008118906A (ru) | 2009-11-20 |
JP5014143B2 (ja) | 2012-08-29 |
CN101330929A (zh) | 2008-12-24 |
IL190693A (en) | 2014-12-31 |
IL190693A0 (en) | 2008-11-03 |
BRPI0617378B8 (pt) | 2022-09-20 |
CA2625773A1 (en) | 2007-04-19 |
EP1941907B1 (en) | 2016-03-23 |
KR20080064154A (ko) | 2008-07-08 |
JPWO2007043641A1 (ja) | 2009-04-16 |
WO2007043641A1 (ja) | 2007-04-19 |
AU2006300234B2 (en) | 2013-01-10 |
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