NO20082194L - Midler for undertrykkelse av skade pa transplanterte oyer etter oytransplantasjon - Google Patents

Midler for undertrykkelse av skade pa transplanterte oyer etter oytransplantasjon

Info

Publication number
NO20082194L
NO20082194L NO20082194A NO20082194A NO20082194L NO 20082194 L NO20082194 L NO 20082194L NO 20082194 A NO20082194 A NO 20082194A NO 20082194 A NO20082194 A NO 20082194A NO 20082194 L NO20082194 L NO 20082194L
Authority
NO
Norway
Prior art keywords
transplanted
receptor antibody
found
dysfunction
islands
Prior art date
Application number
NO20082194A
Other languages
English (en)
Inventor
Yohichi Yasunami
Original Assignee
Univ Fukuoka
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Fukuoka filed Critical Univ Fukuoka
Publication of NO20082194L publication Critical patent/NO20082194L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Transplantation (AREA)
  • Surgery (AREA)
  • Mycology (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Et anti-IL-6-reseptorantistoff er undersøkt med hensyn til dets inhibitoreffekt mot dysfunksjon i transplanterte øyer som oppstår etter øytransplantasjon. Som et resultat er det funnet at anti-IL-6-reseptorantistoffet kan redusere den transplanterte øyens dysfunksjon, forbedre overlevelse av den transplanterte øy og også forbedre den hyperglykemiske tilstanden til en mottaker. Det er også funnet at administrasjon av anti-IL-6-reseptorantistoffet gjør det mulig å forhindre produksjon av et inflammatorisk cytokin i en infiltrerende celle etter transplantasjonen. Således er det nå funnet at dysfunksjon i transplanterte øyer som oppstår etter øytransplantasjon, kan forebygges ved å anvende anti-IL-6-reseptorantistoffet.
NO20082194A 2005-10-14 2008-05-13 Midler for undertrykkelse av skade pa transplanterte oyer etter oytransplantasjon NO20082194L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2005300489 2005-10-14
PCT/JP2006/320441 WO2007043641A1 (ja) 2005-10-14 2006-10-13 膵島移植における移植膵島障害抑制剤

Publications (1)

Publication Number Publication Date
NO20082194L true NO20082194L (no) 2008-07-11

Family

ID=37942862

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20082194A NO20082194L (no) 2005-10-14 2008-05-13 Midler for undertrykkelse av skade pa transplanterte oyer etter oytransplantasjon

Country Status (15)

Country Link
US (1) US8470316B2 (no)
EP (1) EP1941907B1 (no)
JP (1) JP5014143B2 (no)
KR (1) KR101343190B1 (no)
CN (1) CN101330929B (no)
AR (1) AR061400A1 (no)
AU (1) AU2006300234B2 (no)
BR (1) BRPI0617378B8 (no)
CA (1) CA2625773C (no)
HK (1) HK1124533A1 (no)
IL (1) IL190693A (no)
NO (1) NO20082194L (no)
RU (1) RU2446826C2 (no)
WO (1) WO2007043641A1 (no)
ZA (1) ZA200803973B (no)

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EP1941907A4 (en) 2010-01-20
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HK1124533A1 (en) 2009-07-17
WO2007043641A1 (ja) 2007-04-19
US20090220499A1 (en) 2009-09-03
CA2625773A1 (en) 2007-04-19
KR101343190B1 (ko) 2013-12-19
IL190693A0 (en) 2008-11-03
BRPI0617378B1 (pt) 2021-08-10
RU2446826C2 (ru) 2012-04-10
KR20080064154A (ko) 2008-07-08
AR061400A1 (es) 2008-08-27
BRPI0617378B8 (pt) 2022-09-20
EP1941907A1 (en) 2008-07-09
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IL190693A (en) 2014-12-31
BRPI0617378A2 (pt) 2011-07-26
JPWO2007043641A1 (ja) 2009-04-16
ZA200803973B (en) 2009-03-25
RU2008118906A (ru) 2009-11-20
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CA2625773C (en) 2015-05-12
US8470316B2 (en) 2013-06-25

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