MX2012005298A - Maduracion ex-huesped de celulas madre de linea germinal. - Google Patents

Maduracion ex-huesped de celulas madre de linea germinal.

Info

Publication number
MX2012005298A
MX2012005298A MX2012005298A MX2012005298A MX2012005298A MX 2012005298 A MX2012005298 A MX 2012005298A MX 2012005298 A MX2012005298 A MX 2012005298A MX 2012005298 A MX2012005298 A MX 2012005298A MX 2012005298 A MX2012005298 A MX 2012005298A
Authority
MX
Mexico
Prior art keywords
stem cells
germline stem
host maturation
maturation
host
Prior art date
Application number
MX2012005298A
Other languages
English (en)
Other versions
MX344716B (es
Inventor
Fariborz Izadyar
Johnny Yung-Chiong Chow
Constance Yuen
Original Assignee
Primegen Biotech Llc Dba Reprocyte
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Primegen Biotech Llc Dba Reprocyte filed Critical Primegen Biotech Llc Dba Reprocyte
Publication of MX2012005298A publication Critical patent/MX2012005298A/es
Publication of MX344716B publication Critical patent/MX344716B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0608—Germ cells
    • C12N5/0609—Oocytes, oogonia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0608—Germ cells
    • C12N5/061—Sperm cells, spermatogonia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/20—Transition metals
    • C12N2500/24—Iron; Fe chelators; Transferrin
    • C12N2500/25—Insulin-transferrin; Insulin-transferrin-selenium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/70—Undefined extracts
    • C12N2500/80—Undefined extracts from animals
    • C12N2500/84—Undefined extracts from animals from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/06—Anti-neoplasic drugs, anti-retroviral drugs, e.g. azacytidine, cyclophosphamide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/11—Epidermal growth factor [EGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/119—Other fibroblast growth factors, e.g. FGF-4, FGF-8, FGF-10
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/125—Stem cell factor [SCF], c-kit ligand [KL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/13—Nerve growth factor [NGF]; Brain-derived neurotrophic factor [BDNF]; Cilliary neurotrophic factor [CNTF]; Glial-derived neurotrophic factor [GDNF]; Neurotrophins [NT]; Neuregulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/15—Transforming growth factor beta (TGF-β)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C12N2501/235—Leukemia inhibitory factor [LIF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/31—Pituitary sex hormones, e.g. follicle-stimulating hormone [FSH], luteinising hormone [LH]; Chorionic gonadotropins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/385—Hormones with nuclear receptors of the family of the retinoic acid recptor, e.g. RAR, RXR; Peroxisome proliferator-activated receptor [PPAR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/998—Proteins not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/54—Collagen; Gelatin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/90—Substrates of biological origin, e.g. extracellular matrix, decellularised tissue

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Reproductive Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Gynecology & Obstetrics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Se proporcionan métodos para la maduración ex huésped de células de línea germinal inmaduras para la restauración de fertilidad en pacientes con la necesidad de esto.
MX2012005298A 2009-11-05 2010-11-05 Maduración ex-huésped de células madre de línea germinal. MX344716B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25853509P 2009-11-05 2009-11-05
PCT/US2010/055711 WO2011057128A1 (en) 2009-11-05 2010-11-05 Ex host maturation of germline stem cells

Publications (2)

Publication Number Publication Date
MX2012005298A true MX2012005298A (es) 2012-12-17
MX344716B MX344716B (es) 2017-01-03

Family

ID=43478138

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2012005297A MX2012005297A (es) 2009-11-05 2010-11-05 Sistema de banco de celulas madre de linea germinal.
MX2012005298A MX344716B (es) 2009-11-05 2010-11-05 Maduración ex-huésped de células madre de línea germinal.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2012005297A MX2012005297A (es) 2009-11-05 2010-11-05 Sistema de banco de celulas madre de linea germinal.

Country Status (11)

Country Link
US (2) US20120009156A1 (es)
EP (2) EP2496939B1 (es)
JP (2) JP2013514760A (es)
KR (2) KR20130028041A (es)
CN (2) CN102713614A (es)
AU (2) AU2010314989B2 (es)
BR (2) BR112012010675A2 (es)
CA (2) CA2779701A1 (es)
IL (2) IL219601A (es)
MX (2) MX2012005297A (es)
WO (2) WO2011057123A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011057123A1 (en) 2009-11-05 2011-05-12 Primegen Biotech, Llc Dba Reprocyte Germline stem cell banking system
CN109486751B (zh) * 2012-02-14 2022-04-26 华盛顿州立大学 用于无饲养细胞培养牛和猪的精原干细胞的方法
EP2886644A1 (en) * 2013-12-20 2015-06-24 Kallistem Process for implementing in vitro spermatogenesis and associated device
EP3006560A1 (en) * 2014-10-09 2016-04-13 European Molecular Biology Laboratory Miwi2 as a marker for spermatogonial stem cells and method for diagnosing spermatogonial stem cells based on said marker
CN104974982B (zh) * 2015-06-19 2018-07-06 中国农业大学 一种体外培养睾丸组织诱导生成精子细胞的方法
CN106754724A (zh) * 2016-12-09 2017-05-31 西北农林科技大学 一种永生化的牛精原干细胞系及其构建方法
KR101986830B1 (ko) * 2017-09-07 2019-06-07 차의과학대학교 산학협력단 줄기세포 유래 세르톨리유사세포, 그 제조방법, 및 그의 용도
EP3700630A4 (en) * 2017-10-27 2021-11-17 Arteriocyte Medical Systems, Inc. INCREASED FERTILITY DUE TO THROMBOCYTE-RICH PLASMA
JP7021828B2 (ja) * 2017-11-10 2022-02-17 一公 川島 卵巣由来幹細胞の減数分裂誘導法
CA3113255A1 (en) * 2018-09-21 2020-03-26 APstem Therapeutics, Inc. Human pluripotent adult stem cells
US20220330884A1 (en) * 2019-09-06 2022-10-20 The Brighan And Women's Hospital, Inc. Automated evaluation of quality assurance metrics for assisted reproduction procedures
AU2022205084A1 (en) * 2021-01-04 2023-07-13 Paterna Biosciences Inc. Process for establishing a human testicular tissue culture system

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6090622A (en) 1997-03-31 2000-07-18 The Johns Hopkins School Of Medicine Human embryonic pluripotent germ cells
AU2002339299A1 (en) * 2001-05-18 2002-12-03 Cornell Research Foundation, Inc. In vitro production of haploid germ cells
CN1174091C (zh) 2002-01-29 2004-11-03 南京医科大学第一附属医院 人成熟卵泡液在未成熟卵体外成熟技术中的应用
US20030215942A1 (en) 2002-02-14 2003-11-20 Stemcyte, Inc. Undesignated allogeneic stem cell bank
US20040091936A1 (en) 2002-05-24 2004-05-13 Michael West Bank of stem cells for producing cells for transplantation having HLA antigens matching those of transplant recipients, and methods for making and using such a stem cell bank
US7087371B2 (en) 2002-06-28 2006-08-08 The Trustees Of The University Of Pennsylvania Material and methods for the production of sperm and analysis thereof
CN1490400A (zh) * 2002-10-17 2004-04-21 中国科学院力学研究所 毛细管微包被法控制细胞空间分布、形状和大小及其应用
CA2548580A1 (en) * 2003-04-03 2004-10-21 Neostem, Inc. Elective collection and banking of autologous peripheral blood stem cells
EP1649038B1 (en) 2003-06-26 2014-07-02 Litron Laboratories Ltd. Method for the enumeration of micronucleated erythrocyte populations while distinguishing platelets and/or platelet-associated aggregates
US20070011756A1 (en) 2003-08-27 2007-01-11 Takashi Shinohara Method of constructing offspring originating from frozen sperm stem cell
CA2561690A1 (en) 2004-03-30 2005-10-27 Kyoto University Process for producing multipotential stem cell originating in testoid cell
EP1735430A4 (en) * 2004-04-13 2007-10-31 Sungkwang Educational Foundati IN VITRO METHOD FOR ISOLATION, PROLIFERATION AND DIFFERENTIATION OF GERMPLE STEM CELLS
US7955846B2 (en) 2004-05-17 2011-06-07 The General Hospital Corporation Compositions comprising female germline stem cells and methods of use thereof
US20070020759A1 (en) 2004-07-15 2007-01-25 Primegen Biotech Llc Therapeutic reprogramming of germ line stem cells
DK1789534T3 (en) 2004-08-16 2014-11-17 Cellres Corp Pte Ltd ISOLATION OF stem / progenitor cells FOSTER HINDE FROM an umbilical cord
JP2008541734A (ja) * 2005-05-30 2008-11-27 コモンウェルス サイエンティフィック アンド インダストリアル リサーチ オーガニゼイション 基底膜粒子の製造及び使用
US7732202B2 (en) * 2005-10-21 2010-06-08 International Stem Cell Corporation Oxygen tension for the parthenogenic activation of human oocytes for the production of human embryonic stem cells
EP1943335A2 (en) 2005-11-02 2008-07-16 Georg-August-Universität Göttingen Compositions and methods for producing pluripotent cells from adult testis
US20090170059A1 (en) 2005-11-14 2009-07-02 Hans Klingemann Methods for Preparing Cord Matrix Stem Cells (CMSC) for Long Term Storage and for Preparing a Segment of umbilical cord for cryopreservation
CN1800371A (zh) 2005-12-19 2006-07-12 浙江大学 一种人体未成熟卵体外成熟培养方法
KR100707985B1 (ko) 2006-03-10 2007-04-16 세원셀론텍(주) 세포치료제를 생산 및 보관하기 위한 모듈 장치
KR100745362B1 (ko) 2006-03-14 2007-08-02 세원셀론텍(주) 세포치료제 설비의 사용방법 및 이를 이용한 네트워크기반의 프랜차이즈 마켓 비즈니스 방법
WO2007115216A1 (en) 2006-03-30 2007-10-11 Primegen Biotech Llc Reprogramming of adult human testicular stem cells to pluripotent germ-line stem cells
US8759090B2 (en) 2006-10-30 2014-06-24 University Of Central Florida Research Foundation, Inc. Stem cell banking system
US20080132803A1 (en) 2006-11-30 2008-06-05 Hyman Friedlander Method and system for doing business by mining the placental-chord complex
CN100999722B (zh) 2007-01-08 2011-08-03 安徽省立医院 卵巢组织块内不成熟卵母细胞的体外培养成熟方法
US20080189045A1 (en) 2007-02-06 2008-08-07 Moore Thomas E Method for the Collection And Distribution of Cord Blood Stem Cells
CN100548313C (zh) 2007-06-05 2009-10-14 南京农业大学 细管高密度冷冻猪精液的方法及其产品
MX2010001528A (es) * 2007-08-07 2010-10-15 Primegen Biotech Llc Aislamiento, caracterizacion y propagacion de celulas madre de linea germinal.
US20090138354A1 (en) 2007-11-25 2009-05-28 Herbert Zech Methods of Storing and Providing Samples of Cells and Tissue
US8673637B2 (en) * 2008-10-16 2014-03-18 The Board Of Trustees Of The Leland Stanford Junior University Human multipotent germ line stem cells expressing a germ line marker and a pluripotency marker produced by co-culture of testicular tissue
CN101429492B (zh) 2008-12-12 2010-10-06 深圳华大基因科技有限公司 一种猪卵母细胞体外培养成熟方法
WO2011057123A1 (en) 2009-11-05 2011-05-12 Primegen Biotech, Llc Dba Reprocyte Germline stem cell banking system

Also Published As

Publication number Publication date
JP2013514760A (ja) 2013-05-02
KR20120120157A (ko) 2012-11-01
BR112012010750A2 (pt) 2019-09-24
US20120083034A1 (en) 2012-04-05
AU2010314984B2 (en) 2015-09-17
KR20130028041A (ko) 2013-03-18
WO2011057123A8 (en) 2012-06-07
MX344716B (es) 2017-01-03
AU2010314984A8 (en) 2014-02-27
CN102713614A (zh) 2012-10-03
EP2496940B1 (en) 2018-08-15
EP2496939B1 (en) 2017-02-15
CA2779726C (en) 2018-03-06
IL219601A (en) 2017-05-29
CN103154730B (zh) 2015-04-29
AU2010314989A1 (en) 2012-05-24
CA2779701A1 (en) 2011-05-12
WO2011057123A1 (en) 2011-05-12
MX2012005297A (es) 2013-02-26
EP2496940A1 (en) 2012-09-12
CA2779726A1 (en) 2011-05-12
WO2011057128A1 (en) 2011-05-12
AU2010314984A1 (en) 2012-05-24
US9657267B2 (en) 2017-05-23
CN103154730A (zh) 2013-06-12
BR112012010675A2 (pt) 2016-11-29
IL219600A0 (en) 2012-06-28
EP2496939A1 (en) 2012-09-12
US20120009156A1 (en) 2012-01-12
JP2013514969A (ja) 2013-05-02
IL219601A0 (en) 2012-07-31
AU2010314989B2 (en) 2013-10-24

Similar Documents

Publication Publication Date Title
MX344716B (es) Maduración ex-huésped de células madre de línea germinal.
PH12019502292A1 (en) Methods and compositions for treatment of a genetic condition
MX2019003272A (es) Conjugados de afinidad-oligonucleotidos y usos de los mismos.
MX356815B (es) Composiciones y métodos para mejorar el estado bioenergético en células germinales femeninas.
IN2012DN02046A (es)
MX344786B (es) Composiciones y metodos para tratar enfermedad de gaucher.
WO2010111409A3 (en) Pluripotent stem cells
MX364229B (es) Composiciones y metodos para tratar enfermedades cardiovasculares.
EP2667881A4 (en) METHODS OF GENERATING IN VITRO INTERNAL EAR CELLS
EP2443231A4 (en) GENERATION OF INDUCED PLURIPOTENT STEM CELLS FROM UMBILICAL BLOOD
MX2010006576A (es) Composiciones y metodos para producir isopreno.
AU333422S (en) Showerhead
FI20096288A0 (fi) Formulations and methods for culturing stem cells
EP2401361A4 (en) METHOD AND COMPOSITIONS FOR STEM CELL CULTURES
MX2011010955A (es) Terapia complementaria contra el cancer.
EP2580317A4 (en) METHOD AND COMPOSITIONS FOR THE PREPARATION OF CARDIOMYOCYTES FROM STEM CELLS AND THEIR USE
MX2012002909A (es) Metodos y composiciones para su uso en diagnostico de pacientes con cancer.
EP2435558A4 (en) PRODUCTION OF HEAVY INDUCED PLURIPOTENT STEM CELLS GENERALLY CORRECTED
IN2012DN03404A (es)
IL214545A0 (en) Compositions and methods for visualizing and eliminating cancer stem cells
EP4023243A3 (en) Compositions and methods for treating celiac sprue disease
PH12015501187A1 (en) Method for synchronizing time of insemination in gilts
HK1139402A1 (en) Process for the preparation of 2-substituted-5-(1-alkylthio) alkylpyridines
EP2675388A4 (en) ENDODONTIC MILLS, KITS AND METHODS OF USING ENDODONTIC MILLS
MX369983B (es) Plantas que se reproducen vía gametos no reducidos.

Legal Events

Date Code Title Description
FG Grant or registration