MX344716B - Maduración ex-huésped de células madre de línea germinal. - Google Patents

Maduración ex-huésped de células madre de línea germinal.

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Publication number
MX344716B
MX344716B MX2012005298A MX2012005298A MX344716B MX 344716 B MX344716 B MX 344716B MX 2012005298 A MX2012005298 A MX 2012005298A MX 2012005298 A MX2012005298 A MX 2012005298A MX 344716 B MX344716 B MX 344716B
Authority
MX
Mexico
Prior art keywords
stem cells
germline stem
host maturation
maturation
host
Prior art date
Application number
MX2012005298A
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English (en)
Other versions
MX2012005298A (es
Inventor
Izadyar Fariborz
Yung-Chiong Chow Johnny
Yuen Constance
Original Assignee
Primegen Biotech Llc Dba Reprocyte
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Primegen Biotech Llc Dba Reprocyte filed Critical Primegen Biotech Llc Dba Reprocyte
Publication of MX2012005298A publication Critical patent/MX2012005298A/es
Publication of MX344716B publication Critical patent/MX344716B/es

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    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0608Germ cells
    • C12N5/0609Oocytes, oogonia
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    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
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Abstract

La presente invención se refiere a métodos para la maduración ex huésped de células de línea germinal inmaduras para la restauración de fertilidad en pacientes con la necesidad de esto.
MX2012005298A 2009-11-05 2010-11-05 Maduración ex-huésped de células madre de línea germinal. MX344716B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25853509P 2009-11-05 2009-11-05
PCT/US2010/055711 WO2011057128A1 (en) 2009-11-05 2010-11-05 Ex host maturation of germline stem cells

Publications (2)

Publication Number Publication Date
MX2012005298A MX2012005298A (es) 2012-12-17
MX344716B true MX344716B (es) 2017-01-03

Family

ID=43478138

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2012005297A MX2012005297A (es) 2009-11-05 2010-11-05 Sistema de banco de celulas madre de linea germinal.
MX2012005298A MX344716B (es) 2009-11-05 2010-11-05 Maduración ex-huésped de células madre de línea germinal.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2012005297A MX2012005297A (es) 2009-11-05 2010-11-05 Sistema de banco de celulas madre de linea germinal.

Country Status (11)

Country Link
US (2) US9657267B2 (es)
EP (2) EP2496939B1 (es)
JP (2) JP2013514760A (es)
KR (2) KR20130028041A (es)
CN (2) CN103154730B (es)
AU (2) AU2010314989B2 (es)
BR (2) BR112012010750A2 (es)
CA (2) CA2779701A1 (es)
IL (2) IL219600A0 (es)
MX (2) MX2012005297A (es)
WO (2) WO2011057128A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011057128A1 (en) 2009-11-05 2011-05-12 Primegen Biotech, Llc Dba Reprocyte Ex host maturation of germline stem cells
EP3243903A1 (en) * 2012-02-14 2017-11-15 Washington State University Feeder-free method for culture of bovine and porcine spermatogonial stem cells
EP2886644A1 (en) * 2013-12-20 2015-06-24 Kallistem Process for implementing in vitro spermatogenesis and associated device
EP3006560A1 (en) * 2014-10-09 2016-04-13 European Molecular Biology Laboratory Miwi2 as a marker for spermatogonial stem cells and method for diagnosing spermatogonial stem cells based on said marker
CN104974982B (zh) * 2015-06-19 2018-07-06 中国农业大学 一种体外培养睾丸组织诱导生成精子细胞的方法
CN106754724A (zh) * 2016-12-09 2017-05-31 西北农林科技大学 一种永生化的牛精原干细胞系及其构建方法
KR101986830B1 (ko) * 2017-09-07 2019-06-07 차의과학대학교 산학협력단 줄기세포 유래 세르톨리유사세포, 그 제조방법, 및 그의 용도
US20200289574A1 (en) * 2017-10-27 2020-09-17 Arteriocyte Medical Systems, Inc. Augmentation of fertility by platelet rich plasma
JP7021828B2 (ja) * 2017-11-10 2022-02-17 一公 川島 卵巣由来幹細胞の減数分裂誘導法
JP7329265B2 (ja) * 2018-09-21 2023-08-18 アプステム セラピューティクス、インコーポレイテッド ヒト多能性成人幹細胞
JP2022547900A (ja) * 2019-09-06 2022-11-16 ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッド 生殖補助手順に用いられる品質保証の評価指標の自動評価
CN117062613A (zh) * 2021-01-04 2023-11-14 巴特纳生物科学股份有限公司 建立人类睾丸组织培养系统的方法

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6090622A (en) 1997-03-31 2000-07-18 The Johns Hopkins School Of Medicine Human embryonic pluripotent germ cells
WO2002094987A2 (en) 2001-05-18 2002-11-28 Cornell Research Foundation, Inc. In vitro production of haploid germ cells
CN1174091C (zh) * 2002-01-29 2004-11-03 南京医科大学第一附属医院 人成熟卵泡液在未成熟卵体外成熟技术中的应用
US20030215942A1 (en) 2002-02-14 2003-11-20 Stemcyte, Inc. Undesignated allogeneic stem cell bank
US20040091936A1 (en) 2002-05-24 2004-05-13 Michael West Bank of stem cells for producing cells for transplantation having HLA antigens matching those of transplant recipients, and methods for making and using such a stem cell bank
US7087371B2 (en) 2002-06-28 2006-08-08 The Trustees Of The University Of Pennsylvania Material and methods for the production of sperm and analysis thereof
CN1490400A (zh) * 2002-10-17 2004-04-21 中国科学院力学研究所 毛细管微包被法控制细胞空间分布、形状和大小及其应用
CA2548580A1 (en) 2003-04-03 2004-10-21 Neostem, Inc. Elective collection and banking of autologous peripheral blood stem cells
EP1649038B1 (en) 2003-06-26 2014-07-02 Litron Laboratories Ltd. Method for the enumeration of micronucleated erythrocyte populations while distinguishing platelets and/or platelet-associated aggregates
AU2004267976A1 (en) * 2003-08-27 2005-03-10 Kyoto University Method of constructing offspring originating from frozen sperm stem cell
EP1741776A4 (en) 2004-03-30 2007-05-30 Univ Kyoto METHOD FOR PRODUCING A MULTIPOTENTIAL STEM CELL FROM A TESTOID CELL
US20080044395A1 (en) * 2004-04-13 2008-02-21 Sungkwang Educational Foundation In Vitro Method for Isolating, Proliferating and Differentiating Germ-Line Stem Cells
US7955846B2 (en) 2004-05-17 2011-06-07 The General Hospital Corporation Compositions comprising female germline stem cells and methods of use thereof
US20070020759A1 (en) 2004-07-15 2007-01-25 Primegen Biotech Llc Therapeutic reprogramming of germ line stem cells
DK1789534T3 (en) 2004-08-16 2014-11-17 Cellres Corp Pte Ltd ISOLATION OF stem / progenitor cells FOSTER HINDE FROM an umbilical cord
WO2006128216A1 (en) * 2005-05-30 2006-12-07 Commonwealth Scientific And Industrial Research Organisation Preparation and use of basement membrane particles
US7732202B2 (en) * 2005-10-21 2010-06-08 International Stem Cell Corporation Oxygen tension for the parthenogenic activation of human oocytes for the production of human embryonic stem cells
WO2007051625A2 (en) 2005-11-02 2007-05-10 Georg-August-Universität Göttingen Compositions and methods for producing pluripotent cells from adult testis
US20090170059A1 (en) 2005-11-14 2009-07-02 Hans Klingemann Methods for Preparing Cord Matrix Stem Cells (CMSC) for Long Term Storage and for Preparing a Segment of umbilical cord for cryopreservation
CN1800371A (zh) * 2005-12-19 2006-07-12 浙江大学 一种人体未成熟卵体外成熟培养方法
KR100707985B1 (ko) 2006-03-10 2007-04-16 세원셀론텍(주) 세포치료제를 생산 및 보관하기 위한 모듈 장치
KR100745362B1 (ko) 2006-03-14 2007-08-02 세원셀론텍(주) 세포치료제 설비의 사용방법 및 이를 이용한 네트워크기반의 프랜차이즈 마켓 비즈니스 방법
WO2007115216A1 (en) 2006-03-30 2007-10-11 Primegen Biotech Llc Reprogramming of adult human testicular stem cells to pluripotent germ-line stem cells
US8759090B2 (en) 2006-10-30 2014-06-24 University Of Central Florida Research Foundation, Inc. Stem cell banking system
US20080132803A1 (en) 2006-11-30 2008-06-05 Hyman Friedlander Method and system for doing business by mining the placental-chord complex
CN100999722B (zh) * 2007-01-08 2011-08-03 安徽省立医院 卵巢组织块内不成熟卵母细胞的体外培养成熟方法
US20080189045A1 (en) 2007-02-06 2008-08-07 Moore Thomas E Method for the Collection And Distribution of Cord Blood Stem Cells
CN100548313C (zh) 2007-06-05 2009-10-14 南京农业大学 细管高密度冷冻猪精液的方法及其产品
CN102105579A (zh) * 2007-08-07 2011-06-22 普里梅真比奥特斯公司 生殖系干细胞的分离、表征和繁殖
US20090138354A1 (en) 2007-11-25 2009-05-28 Herbert Zech Methods of Storing and Providing Samples of Cells and Tissue
US8673637B2 (en) * 2008-10-16 2014-03-18 The Board Of Trustees Of The Leland Stanford Junior University Human multipotent germ line stem cells expressing a germ line marker and a pluripotency marker produced by co-culture of testicular tissue
CN101429492B (zh) * 2008-12-12 2010-10-06 深圳华大基因科技有限公司 一种猪卵母细胞体外培养成熟方法
WO2011057128A1 (en) 2009-11-05 2011-05-12 Primegen Biotech, Llc Dba Reprocyte Ex host maturation of germline stem cells

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Publication number Publication date
WO2011057128A1 (en) 2011-05-12
US20120009156A1 (en) 2012-01-12
CA2779726A1 (en) 2011-05-12
JP2013514969A (ja) 2013-05-02
KR20120120157A (ko) 2012-11-01
MX2012005297A (es) 2013-02-26
AU2010314984A1 (en) 2012-05-24
WO2011057123A1 (en) 2011-05-12
IL219601A (en) 2017-05-29
JP2013514760A (ja) 2013-05-02
EP2496939B1 (en) 2017-02-15
WO2011057123A8 (en) 2012-06-07
KR20130028041A (ko) 2013-03-18
BR112012010750A2 (pt) 2019-09-24
AU2010314984A8 (en) 2014-02-27
AU2010314984B2 (en) 2015-09-17
AU2010314989A1 (en) 2012-05-24
CA2779701A1 (en) 2011-05-12
CN102713614A (zh) 2012-10-03
EP2496940A1 (en) 2012-09-12
EP2496940B1 (en) 2018-08-15
CN103154730B (zh) 2015-04-29
US9657267B2 (en) 2017-05-23
EP2496939A1 (en) 2012-09-12
MX2012005298A (es) 2012-12-17
AU2010314989B2 (en) 2013-10-24
IL219600A0 (en) 2012-06-28
CA2779726C (en) 2018-03-06
US20120083034A1 (en) 2012-04-05
BR112012010675A2 (pt) 2016-11-29
CN103154730A (zh) 2013-06-12
IL219601A0 (en) 2012-07-31

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