BR112012010750A2 - sistema de armazenamento de células-tronco germinativas humanas - Google Patents
sistema de armazenamento de células-tronco germinativas humanasInfo
- Publication number
- BR112012010750A2 BR112012010750A2 BR112012010750A BR112012010750A BR112012010750A2 BR 112012010750 A2 BR112012010750 A2 BR 112012010750A2 BR 112012010750 A BR112012010750 A BR 112012010750A BR 112012010750 A BR112012010750 A BR 112012010750A BR 112012010750 A2 BR112012010750 A2 BR 112012010750A2
- Authority
- BR
- Brazil
- Prior art keywords
- human germ
- storage system
- stem cell
- germ stem
- cell storage
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0608—Germ cells
- C12N5/0609—Oocytes, oogonia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0608—Germ cells
- C12N5/061—Sperm cells, spermatogonia
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/20—Transition metals
- C12N2500/24—Iron; Fe chelators; Transferrin
- C12N2500/25—Insulin-transferrin; Insulin-transferrin-selenium
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2500/00—Specific components of cell culture medium
- C12N2500/70—Undefined extracts
- C12N2500/80—Undefined extracts from animals
- C12N2500/84—Undefined extracts from animals from mammals
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/06—Anti-neoplasic drugs, anti-retroviral drugs, e.g. azacytidine, cyclophosphamide
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/11—Epidermal growth factor [EGF]
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/119—Other fibroblast growth factors, e.g. FGF-4, FGF-8, FGF-10
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/125—Stem cell factor [SCF], c-kit ligand [KL]
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/13—Nerve growth factor [NGF]; Brain-derived neurotrophic factor [BDNF]; Cilliary neurotrophic factor [CNTF]; Glial-derived neurotrophic factor [GDNF]; Neurotrophins [NT]; Neuregulins
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/15—Transforming growth factor beta (TGF-β)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/235—Leukemia inhibitory factor [LIF]
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/31—Pituitary sex hormones, e.g. follicle-stimulating hormone [FSH], luteinising hormone [LH]; Chorionic gonadotropins
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/38—Hormones with nuclear receptors
- C12N2501/385—Hormones with nuclear receptors of the family of the retinoic acid recptor, e.g. RAR, RXR; Peroxisome proliferator-activated receptor [PPAR]
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/998—Proteins not provided for elsewhere
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- C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes
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- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/54—Collagen; Gelatin
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- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/90—Substrates of biological origin, e.g. extracellular matrix, decellularised tissue
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
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- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Reproductive Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Gynecology & Obstetrics (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Pregnancy & Childbirth (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
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Abstract
sistema de armazenamento de células-tronco germinativas humanas. métodos e sistemas são fornecidos para o isolamento, caracterização, criopreservação e armazenamento de células-tronco germinativas humanas. também são fornecidos métodos para o transplante de células criopreservadas para repopular um órgão reprodutivo estéril.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25853509P | 2009-11-05 | 2009-11-05 | |
PCT/US2010/055706 WO2011057123A1 (en) | 2009-11-05 | 2010-11-05 | Germline stem cell banking system |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112012010750A2 true BR112012010750A2 (pt) | 2019-09-24 |
Family
ID=43478138
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112012010750A BR112012010750A2 (pt) | 2009-11-05 | 2010-11-05 | sistema de armazenamento de células-tronco germinativas humanas |
BR112012010675A BR112012010675A2 (pt) | 2009-11-05 | 2010-11-05 | maturação ex host de células tronco da linhagem germinativa |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112012010675A BR112012010675A2 (pt) | 2009-11-05 | 2010-11-05 | maturação ex host de células tronco da linhagem germinativa |
Country Status (11)
Country | Link |
---|---|
US (2) | US20120009156A1 (pt) |
EP (2) | EP2496940B1 (pt) |
JP (2) | JP2013514760A (pt) |
KR (2) | KR20120120157A (pt) |
CN (2) | CN103154730B (pt) |
AU (2) | AU2010314984B2 (pt) |
BR (2) | BR112012010750A2 (pt) |
CA (2) | CA2779701A1 (pt) |
IL (2) | IL219601A (pt) |
MX (2) | MX2012005297A (pt) |
WO (2) | WO2011057128A1 (pt) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20120009156A1 (en) | 2009-11-05 | 2012-01-12 | Fariborz Izadyar | Germline stem cell banking system |
EP3243903A1 (en) * | 2012-02-14 | 2017-11-15 | Washington State University | Feeder-free method for culture of bovine and porcine spermatogonial stem cells |
EP2886644A1 (en) | 2013-12-20 | 2015-06-24 | Kallistem | Process for implementing in vitro spermatogenesis and associated device |
EP3006560A1 (en) * | 2014-10-09 | 2016-04-13 | European Molecular Biology Laboratory | Miwi2 as a marker for spermatogonial stem cells and method for diagnosing spermatogonial stem cells based on said marker |
CN104974982B (zh) * | 2015-06-19 | 2018-07-06 | 中国农业大学 | 一种体外培养睾丸组织诱导生成精子细胞的方法 |
CN106754724A (zh) * | 2016-12-09 | 2017-05-31 | 西北农林科技大学 | 一种永生化的牛精原干细胞系及其构建方法 |
KR101986830B1 (ko) * | 2017-09-07 | 2019-06-07 | 차의과학대학교 산학협력단 | 줄기세포 유래 세르톨리유사세포, 그 제조방법, 및 그의 용도 |
WO2019084546A1 (en) * | 2017-10-27 | 2019-05-02 | Arteriocyte Medical Systems, Inc. | INCREASE IN FERTILITY BY PLASMA RICH IN PLATELETS |
JP7021828B2 (ja) * | 2017-11-10 | 2022-02-17 | 一公 川島 | 卵巣由来幹細胞の減数分裂誘導法 |
AU2019345279B2 (en) * | 2018-09-21 | 2022-10-27 | APstem Therapeutics, Inc. | Human pluripotent adult stem cells |
CA3150083A1 (en) * | 2019-09-06 | 2021-03-11 | The Brigham And Women's Hospital, Inc. | AUTOMATIC ASSESSMENT OF A QUALITY ASSURANCE MEASURE FOR ASSISTED REPRODUCTIVE PROCEDURES |
WO2022147567A1 (en) * | 2021-01-04 | 2022-07-07 | Paterna Biosciences Llc | Process for establishing a human testicular tissue culture system |
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US6090622A (en) | 1997-03-31 | 2000-07-18 | The Johns Hopkins School Of Medicine | Human embryonic pluripotent germ cells |
AU2002339299A1 (en) * | 2001-05-18 | 2002-12-03 | Cornell Research Foundation, Inc. | In vitro production of haploid germ cells |
CN1174091C (zh) * | 2002-01-29 | 2004-11-03 | 南京医科大学第一附属医院 | 人成熟卵泡液在未成熟卵体外成熟技术中的应用 |
US20030215942A1 (en) | 2002-02-14 | 2003-11-20 | Stemcyte, Inc. | Undesignated allogeneic stem cell bank |
US20040091936A1 (en) | 2002-05-24 | 2004-05-13 | Michael West | Bank of stem cells for producing cells for transplantation having HLA antigens matching those of transplant recipients, and methods for making and using such a stem cell bank |
US7087371B2 (en) | 2002-06-28 | 2006-08-08 | The Trustees Of The University Of Pennsylvania | Material and methods for the production of sperm and analysis thereof |
CN1490400A (zh) * | 2002-10-17 | 2004-04-21 | 中国科学院力学研究所 | 毛细管微包被法控制细胞空间分布、形状和大小及其应用 |
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WO2005017184A2 (en) | 2003-06-26 | 2005-02-24 | Litron Laboratories, Ltd. | Method for the enumeration of micronucleated erythrocyte populations while distinguishing platelets and/or platelet-associated aggregates |
CA2536831A1 (en) * | 2003-08-27 | 2005-03-10 | Kyoto University | Method of constructing offspring originating from frozen sperm stem cell |
JP4314372B2 (ja) | 2004-03-30 | 2009-08-12 | 国立大学法人京都大学 | 精巣細胞由来多能性幹細胞の製造方法 |
JP2007532128A (ja) * | 2004-04-13 | 2007-11-15 | カレッジ オブ メディスン ポーチョン シーエイチエー ユニバーシティ インダストリー−アカデミック コーポレーション ファウンデーション | 生殖幹細胞の単離、増殖および分化のインビトロ方法 |
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EP1943335A2 (en) | 2005-11-02 | 2008-07-16 | Georg-August-Universität Göttingen | Compositions and methods for producing pluripotent cells from adult testis |
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CN1800371A (zh) * | 2005-12-19 | 2006-07-12 | 浙江大学 | 一种人体未成熟卵体外成熟培养方法 |
KR100707985B1 (ko) | 2006-03-10 | 2007-04-16 | 세원셀론텍(주) | 세포치료제를 생산 및 보관하기 위한 모듈 장치 |
KR100745362B1 (ko) | 2006-03-14 | 2007-08-02 | 세원셀론텍(주) | 세포치료제 설비의 사용방법 및 이를 이용한 네트워크기반의 프랜차이즈 마켓 비즈니스 방법 |
WO2007115216A1 (en) | 2006-03-30 | 2007-10-11 | Primegen Biotech Llc | Reprogramming of adult human testicular stem cells to pluripotent germ-line stem cells |
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CN100999722B (zh) * | 2007-01-08 | 2011-08-03 | 安徽省立医院 | 卵巢组织块内不成熟卵母细胞的体外培养成熟方法 |
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CN100548313C (zh) * | 2007-06-05 | 2009-10-14 | 南京农业大学 | 细管高密度冷冻猪精液的方法及其产品 |
WO2009021151A1 (en) * | 2007-08-07 | 2009-02-12 | Primegen Biotech Llc | Isolation, characterization and propagation of germline stem cells |
US20090138354A1 (en) | 2007-11-25 | 2009-05-28 | Herbert Zech | Methods of Storing and Providing Samples of Cells and Tissue |
US8673637B2 (en) * | 2008-10-16 | 2014-03-18 | The Board Of Trustees Of The Leland Stanford Junior University | Human multipotent germ line stem cells expressing a germ line marker and a pluripotency marker produced by co-culture of testicular tissue |
CN101429492B (zh) * | 2008-12-12 | 2010-10-06 | 深圳华大基因科技有限公司 | 一种猪卵母细胞体外培养成熟方法 |
US20120009156A1 (en) | 2009-11-05 | 2012-01-12 | Fariborz Izadyar | Germline stem cell banking system |
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2010
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- 2010-11-05 WO PCT/US2010/055711 patent/WO2011057128A1/en active Application Filing
- 2010-11-05 MX MX2012005297A patent/MX2012005297A/es not_active Application Discontinuation
- 2010-11-05 AU AU2010314984A patent/AU2010314984B2/en not_active Expired - Fee Related
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- 2010-11-05 AU AU2010314989A patent/AU2010314989B2/en not_active Ceased
- 2010-11-05 CA CA2779701A patent/CA2779701A1/en not_active Abandoned
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- 2010-11-05 JP JP2012538044A patent/JP2013514969A/ja active Pending
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- 2010-11-05 BR BR112012010750A patent/BR112012010750A2/pt not_active IP Right Cessation
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- 2010-11-05 EP EP10776067.0A patent/EP2496939B1/en not_active Not-in-force
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US9657267B2 (en) | 2017-05-23 |
CN102713614A (zh) | 2012-10-03 |
BR112012010675A2 (pt) | 2016-11-29 |
IL219601A0 (en) | 2012-07-31 |
WO2011057123A8 (en) | 2012-06-07 |
EP2496940A1 (en) | 2012-09-12 |
AU2010314989B2 (en) | 2013-10-24 |
JP2013514760A (ja) | 2013-05-02 |
WO2011057128A1 (en) | 2011-05-12 |
KR20120120157A (ko) | 2012-11-01 |
MX2012005297A (es) | 2013-02-26 |
CA2779726A1 (en) | 2011-05-12 |
KR20130028041A (ko) | 2013-03-18 |
CN103154730A (zh) | 2013-06-12 |
CN103154730B (zh) | 2015-04-29 |
EP2496939A1 (en) | 2012-09-12 |
AU2010314984B2 (en) | 2015-09-17 |
CA2779726C (en) | 2018-03-06 |
IL219600A0 (en) | 2012-06-28 |
MX2012005298A (es) | 2012-12-17 |
US20120083034A1 (en) | 2012-04-05 |
EP2496939B1 (en) | 2017-02-15 |
AU2010314989A1 (en) | 2012-05-24 |
CA2779701A1 (en) | 2011-05-12 |
JP2013514969A (ja) | 2013-05-02 |
EP2496940B1 (en) | 2018-08-15 |
AU2010314984A8 (en) | 2014-02-27 |
MX344716B (es) | 2017-01-03 |
US20120009156A1 (en) | 2012-01-12 |
AU2010314984A1 (en) | 2012-05-24 |
WO2011057123A1 (en) | 2011-05-12 |
IL219601A (en) | 2017-05-29 |
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