AR049436A1 - Derivado de propano-1,3-diona o sus sales - Google Patents

Derivado de propano-1,3-diona o sus sales

Info

Publication number
AR049436A1
AR049436A1 ARP050102297A ARP050102297A AR049436A1 AR 049436 A1 AR049436 A1 AR 049436A1 AR P050102297 A ARP050102297 A AR P050102297A AR P050102297 A ARP050102297 A AR P050102297A AR 049436 A1 AR049436 A1 AR 049436A1
Authority
AR
Argentina
Prior art keywords
lower alkyl
substituted
propane
halogen
ring
Prior art date
Application number
ARP050102297A
Other languages
English (en)
Inventor
Masaaki Hirano
Eiji Kawaminami
Shunichiro Matsumoto
Kei Ohnuki
Kazuyoshi Obitsu
Toshiyuki Kusayama
Isao Kinoyama
Original Assignee
Astellas Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astellas Pharma Inc filed Critical Astellas Pharma Inc
Publication of AR049436A1 publication Critical patent/AR049436A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A61P5/08—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH for decreasing, blocking or antagonising the activity of the anterior pituitary hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente trata de derivado de propano-1,3-diona o sus sales, composiciones farmacéuticas que los contienen y usos en enfermedades que dependen de las hormonas sexuales. Reivindicacion 1: Un derivado de la propano-1,3-diona representado por la formula general (1) o una de sus sales farmacéuticamente aceptable. [Los símbolos de la formula tienen el significado que se les asigna seguidamente: anillo A: benceno que puede estar sustituido, piridina que puede estar sustituida o anillo de tiofeno; anillo B: benceno o anillo de tiofeno; R1: H o -CO-alquilo inferior; R2: H, -O-R5, -N(R6)R7, -N3, -S(O)m-alquilo inferior, -S(O)m-N(R6)R7, halogeno, piridilo o imidazolilo que puede estar sustituido; R5: H, alquilo inferior, -CO-alquilo inferior que puede estar sustituido o -CO-O-alquilo inferior que puede estar sustituido; R6 y R7: pueden ser iguales o diferentes entre sí y cada uno es H, alquilo inferior o -CO-alquilo inferior, con la condicion de que R1 y R2 juntos formen dioxolano que puede estar sustituido, m es 0, 1 o 2; R3 es H o alquilo inferior; R401 y R402 pueden ser iguales o diferentes entre sí y cada uno es H, halogeno, OH, -O-alquilo inferior o alquilo inferior; X es enlace, alquileno inferior que puede estar sustituido o cicloalcanedilo; R101, R102, R103 y R104: pueden ser iguales o diferentes entre sí y cada uno es H, halogeno, OH o alquilo inferior que puede estar sustituido con -O-(arilo o heteroarilo)].
ARP050102297A 2004-06-04 2005-06-06 Derivado de propano-1,3-diona o sus sales AR049436A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2004166486 2004-06-04
JP2005099815 2005-03-30

Publications (1)

Publication Number Publication Date
AR049436A1 true AR049436A1 (es) 2006-08-02

Family

ID=35462868

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP050102297A AR049436A1 (es) 2004-06-04 2005-06-06 Derivado de propano-1,3-diona o sus sales

Country Status (16)

Country Link
US (2) US7709519B2 (es)
EP (1) EP1752452A4 (es)
JP (1) JP4595938B2 (es)
CN (1) CN1964950A (es)
AR (1) AR049436A1 (es)
AU (1) AU2005250273B2 (es)
BR (1) BRPI0511796A (es)
CA (1) CA2568590C (es)
IL (1) IL179437A (es)
MX (1) MXPA06014131A (es)
NO (1) NO20070074L (es)
NZ (1) NZ552372A (es)
RU (1) RU2347781C2 (es)
TW (1) TWI342307B (es)
UA (1) UA83928C2 (es)
WO (1) WO2005118556A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ552372A (en) 2004-06-04 2009-11-27 Astellas Pharma Inc Propane-1,3-dione derivative or its salt
TW200722420A (en) * 2005-03-31 2007-06-16 Astellas Pharma Inc Propane-1,3-dion derivative or salt thereof
EP2095818A1 (en) * 2008-02-29 2009-09-02 AEterna Zentaris GmbH Use of LHRH antagonists at non-castrating doses
RS56855B1 (sr) * 2010-08-18 2018-04-30 Samumed Llc Diketoni i hidroksiketoni kao aktivatori katenin signalnog puta
CN104603114B (zh) * 2012-09-07 2017-06-20 安斯泰来制药株式会社 磺酰脒化合物的制造方法
BR112015020391B1 (pt) 2013-02-22 2022-07-26 Samumed, Llc Gama-dicetonas como ativadoras da via de sinalização de wnt/beta-catenina
US9618507B2 (en) 2014-02-24 2017-04-11 Betanien Hospital Methods of treating rheumatoid arthritis
BR112017003959B1 (pt) 2014-08-20 2022-08-02 Samumed, Llc Uso de um composto de fórmula i ou um sal dermatologicamente aceitável do mesmo
US10821152B2 (en) 2014-08-26 2020-11-03 Betanien Hospital Methods, agents and compositions for treatment of inflammatory conditions
WO2017170884A1 (ja) * 2016-03-31 2017-10-05 富山化学工業株式会社 新規なヒドロキサム酸誘導体の製造方法およびその中間体

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Also Published As

Publication number Publication date
EP1752452A9 (en) 2007-12-12
RU2006142689A (ru) 2008-06-10
CN1964950A (zh) 2007-05-16
IL179437A (en) 2011-11-30
US20100173946A1 (en) 2010-07-08
US7709519B2 (en) 2010-05-04
JP4595938B2 (ja) 2010-12-08
EP1752452A4 (en) 2010-07-14
UA83928C2 (ru) 2008-08-26
NZ552372A (en) 2009-11-27
US8076367B2 (en) 2011-12-13
EP1752452A1 (en) 2007-02-14
JPWO2005118556A1 (ja) 2008-04-03
CA2568590A1 (en) 2005-12-15
MXPA06014131A (es) 2007-03-07
US20090018177A1 (en) 2009-01-15
BRPI0511796A (pt) 2008-01-15
TWI342307B (en) 2011-05-21
CA2568590C (en) 2011-01-18
WO2005118556A1 (ja) 2005-12-15
RU2347781C2 (ru) 2009-02-27
NO20070074L (no) 2007-03-02
AU2005250273B2 (en) 2010-10-14
AU2005250273A1 (en) 2005-12-15
TW200613281A (en) 2006-05-01
IL179437A0 (en) 2007-05-15

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