AR042921A2 - Aparatos y metodos para pulverizar un polvo o un medicamento en polvo, y un receptaculo para contener un medicamento en polvo - Google Patents

Aparatos y metodos para pulverizar un polvo o un medicamento en polvo, y un receptaculo para contener un medicamento en polvo

Info

Publication number
AR042921A2
AR042921A2 ARP040100206A ARP040100206A AR042921A2 AR 042921 A2 AR042921 A2 AR 042921A2 AR P040100206 A ARP040100206 A AR P040100206A AR P040100206 A ARP040100206 A AR P040100206A AR 042921 A2 AR042921 A2 AR 042921A2
Authority
AR
Argentina
Prior art keywords
valve
powder
handle
cylinder
drug
Prior art date
Application number
ARP040100206A
Other languages
English (en)
Original Assignee
Inhale Therapeutic Syst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inhale Therapeutic Syst filed Critical Inhale Therapeutic Syst
Publication of AR042921A2 publication Critical patent/AR042921A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A61M15/0035—Piercing means
    • A61M15/0036—Piercing means hollow piercing means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A61M15/004—Details of the piercing or cutting means with fixed piercing or cutting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A61M15/0041—Details of the piercing or cutting means with movable piercing or cutting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0051—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged on a tape, e.g. strips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0053—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type or way of disposal
    • A61M15/0055—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type or way of disposal the used dosages being coiled
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0086—Inhalation chambers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/02—General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0233—Conductive materials, e.g. antistatic coatings for spark prevention
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/07—General characteristics of the apparatus having air pumping means
    • A61M2205/071—General characteristics of the apparatus having air pumping means hand operated
    • A61M2205/073—Syringe, piston type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/60—General characteristics of the apparatus with identification means
    • A61M2205/6045—General characteristics of the apparatus with identification means having complementary physical shapes for indexing or registration purposes

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Medicinal Preparation (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Catching Or Destruction (AREA)
  • Nozzles (AREA)

Abstract

El aparato para pulverizar un medicamento en polvo comprende un alojamiento y una fuente de gas presurizado para pulverizar el medicamento en polvo que comprende un cilindro de presurización; un émbolo que se desliza dentro del cilindro; una válvula de disparo en comunicación con el cilindro; y un montaje de mango que tiene un mango conectado funcionalmente al émbolo y un mecanismo para cerrar la válvula operativamente conectado al mango, en donde el movimiento del mango en una dirección mueve el mecanismo para cerrar la válvula de modo de contactar y cerrar la válvula en una posición cerrada permanentemente, y el movimiento del mango en la otra dirección cierra la válvula y traslada el émbolo en dirección axial dentro del cilindro para producir gas presurizado mientras la válvula permanece en una posición cerrada permanente de modo de mantener el gas bajo presión hasta que sea liberado.
ARP040100206A 1994-09-21 2004-01-23 Aparatos y metodos para pulverizar un polvo o un medicamento en polvo, y un receptaculo para contener un medicamento en polvo AR042921A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/309,691 US5785049A (en) 1994-09-21 1994-09-21 Method and apparatus for dispersion of dry powder medicaments
US08/487,184 US5740794A (en) 1994-09-21 1995-06-07 Apparatus and methods for dispersing dry powder medicaments

Publications (1)

Publication Number Publication Date
AR042921A2 true AR042921A2 (es) 2005-07-06

Family

ID=23199254

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP040100206A AR042921A2 (es) 1994-09-21 2004-01-23 Aparatos y metodos para pulverizar un polvo o un medicamento en polvo, y un receptaculo para contener un medicamento en polvo

Country Status (8)

Country Link
US (2) US5785049A (es)
EP (1) EP1917992A3 (es)
KR (3) KR100400063B1 (es)
AR (1) AR042921A2 (es)
DE (1) DE69535725T2 (es)
MY (1) MY113727A (es)
TW (1) TW287110B (es)
ZA (1) ZA957933B (es)

Families Citing this family (339)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA26230A (uk) * 1990-03-02 1999-07-19 Глексо Груп Лімітед Іhгалятор для спільhого використаhhя з лікувальhим блоком і лікувальhий блок
SK280967B6 (sk) 1990-03-02 2000-10-09 Glaxo Group Limited Inhalačný prístroj
US6536427B2 (en) 1990-03-02 2003-03-25 Glaxo Group Limited Inhalation device
GB9004781D0 (en) * 1990-03-02 1990-04-25 Glaxo Group Ltd Device
DK0592540T3 (da) * 1991-07-02 2000-06-26 Inhale Inc Fremgangsmåde og indretning til aflevering af aerosoliserede medikamenter
US6681767B1 (en) 1991-07-02 2004-01-27 Nektar Therapeutics Method and device for delivering aerosolized medicaments
US6582728B1 (en) * 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
CN1131080C (zh) 1994-09-21 2003-12-17 吸入治疗系统 用于喷洒干的粉末药物的方法和装置
CA2213638C (en) * 1995-02-24 2004-05-04 Nanosystems L.L.C. Aerosols containing nanoparticle dispersions
JP3708553B2 (ja) * 1995-04-14 2005-10-19 ネクター セラピューティクス 向上した分散性を有する粉末型薬理組成物
US6428771B1 (en) * 1995-05-15 2002-08-06 Pharmaceutical Discovery Corporation Method for drug delivery to the pulmonary system
US20040237961A1 (en) * 1995-06-08 2004-12-02 Snow John Medlin Inhalation actuated device for use with metered dose inhalers (MDIs)
US6672304B1 (en) 1995-06-08 2004-01-06 Innovative Devices, Llc Inhalation actuated device for use with metered dose inhalers (MDIs)
US6209538B1 (en) 1995-08-02 2001-04-03 Robert A. Casper Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament
FR2738152B1 (fr) * 1995-09-04 1998-01-23 Tebro Dispositif de pre-dosage de produit pulverulent pour un distributeur de produit
CA2245799C (en) * 1996-02-21 2006-03-21 Schering Corporation Powdered medication inhaler
WO1997040876A2 (en) * 1996-04-25 1997-11-06 Alfred Von Schuckmann Inhaler
US6197835B1 (en) 1996-05-13 2001-03-06 Universidad De Sevilla Device and method for creating spherical particles of uniform size
US6386463B1 (en) 1996-05-13 2002-05-14 Universidad De Sevilla Fuel injection nozzle and method of use
US6405936B1 (en) 1996-05-13 2002-06-18 Universidad De Sevilla Stabilized capillary microjet and devices and methods for producing same
US6299145B1 (en) 1996-05-13 2001-10-09 Universidad De Sevilla Device and method for fluid aeration via gas forced through a liquid within an orifice of a pressure chamber
ES2140998B1 (es) 1996-05-13 2000-10-16 Univ Sevilla Procedimiento de atomizacion de liquidos.
US6196525B1 (en) 1996-05-13 2001-03-06 Universidad De Sevilla Device and method for fluid aeration via gas forced through a liquid within an orifice of a pressure chamber
US6792940B2 (en) 1996-05-13 2004-09-21 Universidad De Sevilla Device and method for creating aerosols for drug delivery
US6187214B1 (en) 1996-05-13 2001-02-13 Universidad De Seville Method and device for production of components for microfabrication
US6595202B2 (en) 1996-05-13 2003-07-22 Universidad De Sevilla Device and method for creating aerosols for drug delivery
US6189803B1 (en) 1996-05-13 2001-02-20 University Of Seville Fuel injection nozzle and method of use
US6458574B1 (en) 1996-09-12 2002-10-01 Transkaryotic Therapies, Inc. Treatment of a α-galactosidase a deficiency
GB2318737B (en) * 1996-10-30 2000-06-14 Bespak Plc Improved inhalers
US20030203036A1 (en) 2000-03-17 2003-10-30 Gordon Marc S. Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
SE9700424D0 (sv) * 1997-02-07 1997-02-07 Astra Ab Powder inhaler
DE19704849B4 (de) * 1997-02-08 2011-02-17 Ing. Erich Pfeiffer Gmbh Austragvorrichtung für Medien
CA2212430A1 (en) * 1997-08-07 1999-02-07 George Volgyesi Inhalation device
US20060165606A1 (en) * 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
PE56799A1 (es) 1997-10-10 1999-06-10 Inhale Therapeutic Syst Metodo y aparato para transportar polvo
CA2314920C (en) 1997-12-17 2009-04-14 Universidad De Sevilla Device and method for creating aerosols for drug delivery
RO121834B1 (ro) * 1998-03-16 2008-06-30 Inhale Therapeutic Systems, Inc. Dispozitiv pentru administrarea unui agent activ
SE9801114D0 (sv) * 1998-03-30 1998-03-30 Astra Ab Inhalation device
US6257233B1 (en) * 1998-06-04 2001-07-10 Inhale Therapeutic Systems Dry powder dispersing apparatus and methods for their use
EP1685866A3 (en) * 1998-06-04 2013-07-10 Nektar Therapeutics Dry powder dispersing apparatus and methods for their use
PT1089783E (pt) * 1998-06-22 2005-01-31 Astrazeneca Ab Dispositivo para esvaziar por aspiracao cavidades contendo po
US6593133B1 (en) 1998-07-06 2003-07-15 Nsgene A/S Neurotrophic factors
DE19831525A1 (de) * 1998-07-14 2000-01-20 Pfeiffer Erich Gmbh & Co Kg Spender für Medien
ES2310047T3 (es) 1998-08-18 2008-12-16 The Regents Of The University Of California Antagonistas del receptor del factor de crecimiento epidermico para el tratamiento de la hipersecrecion de mucosidad en los pulmones.
UA73924C2 (en) * 1998-10-09 2005-10-17 Nektar Therapeutics Device for delivering active agent formulation to lungs of human patient
US20040141925A1 (en) * 1998-11-12 2004-07-22 Elan Pharma International Ltd. Novel triamcinolone compositions
US7521068B2 (en) * 1998-11-12 2009-04-21 Elan Pharma International Ltd. Dry powder aerosols of nanoparticulate drugs
US6450189B1 (en) 1998-11-13 2002-09-17 Universidad De Sevilla Method and device for production of components for microfabrication
CA2356637C (en) 1998-12-22 2011-09-13 The University Of North Carolina At Chapel Hill Compounds and methods for the treatment of airway diseases and for the delivery of airway drugs
EP1169053A1 (en) 1999-04-13 2002-01-09 Inhale Therapeutic Systems, Inc. Pulmonary administration of dry powder formulations for treating infertility
EP1183061B2 (en) * 1999-06-05 2012-10-17 Innovata Biomed Limited Medicament delivery system
GB2353222B (en) * 1999-06-23 2001-09-19 Cambridge Consultants Inhalers
PT1808438E (pt) * 1999-06-29 2015-01-14 Mannkind Corp Purificação e estabilização de péptidos e proteínas em agentes farmacêuticos
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US6606992B1 (en) 1999-06-30 2003-08-19 Nektar Therapeutics Systems and methods for aerosolizing pharmaceutical formulations
US7305986B1 (en) 1999-07-23 2007-12-11 Mannkind Corporation Unit dose capsules for use in a dry powder inhaler
US7464706B2 (en) * 1999-07-23 2008-12-16 Mannkind Corporation Unit dose cartridge and dry powder inhaler
GB9920839D0 (en) * 1999-09-04 1999-11-10 Innovata Biomed Ltd Inhaler
WO2001026720A1 (en) * 1999-10-12 2001-04-19 Shl Medical Ab Inhaler
EP1666028B1 (en) * 1999-10-29 2010-03-24 Novartis AG Dry powder compositions having improved dispersivity
US6679256B2 (en) 1999-12-17 2004-01-20 Nektar Therapeutics Systems and methods for extracting powders from receptacles
US7304750B2 (en) * 1999-12-17 2007-12-04 Nektar Therapeutics Systems and methods for non-destructive mass sensing
US20010035184A1 (en) 1999-12-17 2001-11-01 Carlos Schuler Systems and methods for treating packaged powders
HUP0203751A3 (en) 2000-01-10 2005-01-28 Maxygen Holdings Ltd Redwood C G-csf conjugates
WO2001078817A1 (en) * 2000-02-25 2001-10-25 Dura Pharmaceuticals, Inc. Dosing system for a dry powder inhaler
ATE392885T1 (de) 2000-02-28 2008-05-15 Pharmakodex Ltd Verabreichungssystemen für oral anzuwendende arzneimittel
US6748944B1 (en) 2000-05-03 2004-06-15 Dellavecchia Michael Anthony Ultrasonic dosage device and method
US7442388B2 (en) * 2000-05-10 2008-10-28 Weers Jeffry G Phospholipid-based powders for drug delivery
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
US6948494B1 (en) * 2000-05-10 2005-09-27 Innovative Devices, Llc. Medicament container with same side airflow inlet and outlet and method of use
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
US20030003057A1 (en) * 2000-07-07 2003-01-02 Jeffry Weers Methods for administering leuprolide by inhalation
US20040176391A1 (en) * 2002-12-31 2004-09-09 Nektar Therapeutics Aerosolizable pharmaceutical formulation for fungal infection therapy
WO2001087378A2 (en) * 2000-05-12 2001-11-22 Dura Pharmaceuticals, Inc. Compressed gas dry powder inhaler
US6668827B2 (en) 2000-05-16 2003-12-30 Nektar Therapeutics Systems devices and methods for opening receptacles having a powder to be fluidized
US20020000225A1 (en) 2000-06-02 2002-01-03 Carlos Schuler Lockout mechanism for aerosol drug delivery devices
GB2364919A (en) * 2000-07-21 2002-02-13 Cambridge Consultants Inhalers
AU2001283546A1 (en) * 2000-08-14 2002-02-25 Advanced Inhalation Research, Inc. Inhalation device and method
SE517227C2 (sv) * 2000-09-25 2002-05-14 Microdrug Ag Inhalator för torrt pulver med folieskärare
GB0023654D0 (en) * 2000-09-27 2000-11-08 Cambridge Consultants Device for administering doses of particulate material
US6722364B2 (en) * 2001-01-12 2004-04-20 Becton, Dickinson And Company Medicament inhalation delivery devices and methods for using the same
US6443152B1 (en) * 2001-01-12 2002-09-03 Becton Dickinson And Company Medicament respiratory delivery device
WO2002056948A1 (en) * 2001-01-17 2002-07-25 Vectura Limited An inhaler device
US7442370B2 (en) 2001-02-01 2008-10-28 Biogen Idec Ma Inc. Polymer conjugates of mutated neublastin
CA2435982C (en) * 2001-02-06 2014-05-06 Innovata Biomed Limited Medicaments
YU48703A (sh) 2001-02-27 2006-05-25 Maxygen Aps Novi interferonu beta-slični molekuli
US7276580B2 (en) * 2001-03-12 2007-10-02 Biogen Idec Ma Inc. Neurotrophic factors
US6887462B2 (en) 2001-04-09 2005-05-03 Chiron Corporation HSA-free formulations of interferon-beta
US6766799B2 (en) * 2001-04-16 2004-07-27 Advanced Inhalation Research, Inc. Inhalation device
WO2002092154A1 (en) * 2001-04-26 2002-11-21 New England Pharmaceuticals, Inc. Metered dose delivery device for liquid and powder agents
US7905230B2 (en) * 2001-05-09 2011-03-15 Novartis Ag Metered dose inhaler with lockout
EP1392383A2 (en) * 2001-05-10 2004-03-03 Vectura Delivery Devices Limited Inhalers
GB0112888D0 (en) * 2001-05-26 2001-07-18 Innovata Biomed Ltd Device
EG24184A (en) * 2001-06-15 2008-10-08 Otsuka Pharma Co Ltd Dry powder inhalation system for transpulmonary
EP1397173A1 (en) * 2001-06-20 2004-03-17 Nektar Therapeutics Powder aerosolization apparatus and method
JP2004531334A (ja) 2001-06-20 2004-10-14 ネクター セラピューティクス エアゾール薬剤の投与装置及び方法のための流量レギュレータ
NZ519403A (en) * 2001-06-21 2005-03-24 Pfizer Prod Inc Use of insulin in a medicament to reduce weight gain in a diabetic patient who is using exogenous insulin to control blood sugar levels
WO2003026559A2 (en) * 2001-09-28 2003-04-03 Kurve Technology, Inc Nasal nebulizer
US6779520B2 (en) * 2001-10-30 2004-08-24 Iep Pharmaceutical Devices Inc. Breath actuated dry powder inhaler
GB0128148D0 (en) * 2001-11-23 2002-01-16 Innovata Biomed Ltd Assembly
US20030099601A1 (en) * 2001-11-27 2003-05-29 Gordon Marc S. Inhalation lung surfactant therapy
EP1458360B1 (en) 2001-12-19 2011-05-11 Novartis AG Pulmonary delivery of aminoglycosides
US20050051453A1 (en) * 2001-12-21 2005-03-10 Inhale Therapeutic Systems, Inc. Sealing a pharmaceutical formulation in a package
WO2003057593A1 (en) * 2001-12-21 2003-07-17 Nektar Therapeutics Capsule package with moisture barrier
US20030129242A1 (en) * 2002-01-04 2003-07-10 Bosch H. William Sterile filtered nanoparticulate formulations of budesonide and beclomethasone having tyloxapol as a surface stabilizer
ATE385193T1 (de) 2002-03-20 2008-02-15 Mannkind Corp Inhalationsgerät
GR1004350B (el) * 2002-03-29 2003-09-26 Συσκευη εισπνοων ξηρης σκονης
US20030235538A1 (en) * 2002-04-09 2003-12-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Method for the administration of an anticholinergic by inhalation
ES2367257T3 (es) 2002-04-25 2011-10-31 Shire Human Genetic Therapies, Inc. Tratamiento de deficit de alfa-galactosidasa a.
WO2003099359A1 (en) * 2002-05-09 2003-12-04 Kurve Technology, Inc. Particle dispersion chamber for nasal nebulizer
US6889690B2 (en) 2002-05-10 2005-05-10 Oriel Therapeutics, Inc. Dry powder inhalers, related blister devices, and associated methods of dispensing dry powder substances and fabricating blister packages
US7185651B2 (en) * 2002-06-18 2007-03-06 Nektar Therapeutics Flow regulator for aerosol drug delivery and methods
US6799571B1 (en) * 2002-06-19 2004-10-05 Molecular Rotation, Llc Medicinal powder delivery system
US6941980B2 (en) * 2002-06-27 2005-09-13 Nektar Therapeutics Apparatus and method for filling a receptacle with powder
JP4571776B2 (ja) * 2002-11-05 2010-10-27 Ｊｘ日鉱日石エネルギー株式会社 潤滑油組成物
WO2005000195A2 (en) * 2002-11-13 2005-01-06 Rosenberg Yvonne J A pretreatment or post exposure treatment for exposure to a toxic substance by pulmonary delivery (inhaler) of a bioscavenger
US7516741B2 (en) * 2002-12-06 2009-04-14 Novartis Ag Aerosolization apparatus with feedback mechanism
PL208288B1 (pl) * 2002-12-13 2011-04-29 Otsuka Pharma Co Ltd Inhalator do przezpłucnego podawania leku
AU2003303036A1 (en) * 2002-12-13 2004-07-09 Pfizer Products Inc. Method of decreasing hepatic glucose output in diabetic patients
AU2003283690A1 (en) * 2002-12-19 2004-07-14 Koninklijke Philips Electronics N.V. Discrete-amount fluid-dispensing system for a personal care device
US20040206350A1 (en) * 2002-12-19 2004-10-21 Nektar Therapeutics Aerosolization apparatus with non-circular aerosolization chamber
US20050236296A1 (en) * 2002-12-30 2005-10-27 Nektar Therapeutics (Formerly Inhale Therapeutic Systems, Inc.) Carry case for aerosolization apparatus
EP1578536B1 (en) * 2002-12-30 2017-02-08 Novartis AG Prefilming atomizer
TR200502522T2 (tr) * 2002-12-31 2005-09-21 Nektar Therapeutics Çözünmez bir aktif madde içeren farmasötik formülasyon
US7669596B2 (en) * 2002-12-31 2010-03-02 Novartis Pharma Ag Aerosolization apparatus with rotating capsule
US20040187866A1 (en) * 2003-03-31 2004-09-30 Nathaniel Hughes Liquid medicament delivery system
HUE026950T2 (en) * 2003-04-09 2016-08-29 Novartis Ag Nozzle with guide wire for puncturing the capsule
JP4943838B2 (ja) 2003-04-09 2012-05-30 ネクター セラピューティクス 空気入口シールドを備えたエアゾール化装置
US8869794B1 (en) 2003-04-09 2014-10-28 Novartis Pharma Ag Aerosolization apparatus with capsule puncturing member
EP1897552B1 (en) 2003-04-18 2009-06-17 Biogen Idec MA Inc. Polymer-conjugated glycosylated neublastin
SI1663235T1 (sl) 2003-08-18 2013-12-31 Parion Sciences, Inc. Zaščiteni pirazinoilgvanidinski blokatorji natrijevega kanala
WO2005023334A2 (en) * 2003-09-05 2005-03-17 Kurve Technology, Inc. Nasal adapter for the base of the nose
WO2005023335A2 (en) * 2003-09-05 2005-03-17 Kurve Technology, Inc. Integrated nebulizer and particle dispersing chamber for delivery of medicament
GB2405798A (en) * 2003-09-15 2005-03-16 Vectura Ltd Dry powder inhaler with primary and secondary piercing elements and a medicament pack for use with an inhalation device.
GB0322544D0 (en) * 2003-09-26 2003-10-29 Innovata Biomed Ltd Apparatus
US7338171B2 (en) * 2003-10-27 2008-03-04 Jen-Chuen Hsieh Method and apparatus for visual drive control
US7377277B2 (en) * 2003-10-27 2008-05-27 Oriel Therapeutics, Inc. Blister packages with frames and associated methods of fabricating dry powder drug containment systems
US7451761B2 (en) * 2003-10-27 2008-11-18 Oriel Therapeutics, Inc. Dry powder inhalers, related blister package indexing and opening mechanisms, and associated methods of dispensing dry powder substances
WO2005044226A2 (en) * 2003-11-04 2005-05-19 Nectar Therapeutics Lipid formulations for spontaneous drug encapsulation
AU2004294889B2 (en) * 2003-12-03 2010-08-26 Boehringer Ingelheim International Gmbh Medical product containing tiotropium
SE0303570L (sv) * 2003-12-03 2005-06-04 Microdrug Ag Fukt-känslig medicinsk produkt
SE0303270L (sv) * 2003-12-03 2005-06-04 Microdrug Ag Metod för administration av tiotropium
SE0303569L (sv) * 2003-12-03 2005-06-04 Microdrug Ag DPI för avlämning av fuktkänsliga medikament
US7159507B2 (en) 2003-12-23 2007-01-09 Philip Morris Usa Inc. Piston pump useful for aerosol generation
WO2005067898A2 (en) * 2004-01-07 2005-07-28 Nektar Therapeutics Improved sustained release compositions for pulmonary administration of insulin
AU2005204378B2 (en) * 2004-01-12 2009-01-22 Mannkind Corporation A method of reducing serum proinsulin levels in type 2 diabetics
US7624733B2 (en) 2004-02-09 2009-12-01 Oriel Therapeutics, Inc. Inhalers with extendable/retractable forward member and associated methods of dispensing inhalant substances
WO2005079755A2 (en) * 2004-02-12 2005-09-01 Nektar Therapeutics Interleukin-13 antagonist powders, spray-dried particles, and methods
CN1922836A (zh) * 2004-02-26 2007-02-28 诺和诺德公司 一种用于对无线通信设备进行安全配对的方法和系统
ES2328048T3 (es) * 2004-03-12 2009-11-06 Biodel, Inc. Composiciones de insulina con absorcion mejorada.
US20080248999A1 (en) * 2007-04-04 2008-10-09 Biodel Inc. Amylin formulations
US20080090753A1 (en) 2004-03-12 2008-04-17 Biodel, Inc. Rapid Acting Injectable Insulin Compositions
WO2005091540A1 (en) * 2004-03-19 2005-09-29 Novo Nordisk A/S A reduced size transmission data packet header format for a medical device
EP1735729A2 (en) * 2004-03-26 2006-12-27 Novo Nordisk A/S Device for displaying data relevant for a diabetic patient
GB0407627D0 (en) * 2004-04-02 2004-05-05 Vectura Ltd Corkscrew pump
EP1744800B1 (en) * 2004-04-21 2016-06-22 Innovata Biomed Limited Inhaler
GB0409197D0 (en) 2004-04-24 2004-05-26 Innovata Biomed Ltd Device
US7723306B2 (en) * 2004-05-10 2010-05-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Spray-dried powder comprising at least one 1,4 O-linked saccharose-derivative and methods for their preparation
US7727962B2 (en) * 2004-05-10 2010-06-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Powder comprising new compositions of oligosaccharides and methods for their preparation
US7611709B2 (en) * 2004-05-10 2009-11-03 Boehringer Ingelheim Pharma Gmbh And Co. Kg 1,4 O-linked saccharose derivatives for stabilization of antibodies or antibody derivatives
SE530006C2 (sv) * 2004-06-18 2008-02-05 Mederio Ag Inhalator som använder balja
BE1015883A3 (fr) * 2004-06-08 2005-10-04 Occhio Procede et dispositif de dispersion de poudres seches.
WO2006002178A1 (en) 2004-06-18 2006-01-05 Novartis Vaccines And Diagnostics Inc. Methods of treatment of endobronchial infections
US8513204B2 (en) * 2004-06-21 2013-08-20 Novartis Ag Compositions comprising amphotericin B, mehods and systems
BRPI0512326A (pt) * 2004-06-21 2008-02-26 Nektar Therapeutics composições compreendendo anfotericina b, métodos e sistemas
UA91512C2 (ru) 2004-07-19 2010-08-10 Биокон Лимитед Коньюгати олигомеров инсулина, их композиция (варианты) и применение
KR20110126732A (ko) * 2004-08-19 2011-11-23 바이오겐 아이덱 엠에이 인코포레이티드 뉴블라스틴 변형체
EP1784203B1 (en) 2004-08-19 2010-06-30 Biogen Idec MA Inc. Refolding transforming growth factor beta family proteins
AU2005277208B2 (en) 2004-08-20 2011-11-24 Mannkind Corporation Catalysis of diketopiperazine synthesis
DK1791542T3 (en) 2004-08-23 2015-06-15 Mannkind Corp Diketopiperazinsalte for pharmaceutical delivery
US20080270186A1 (en) * 2004-08-24 2008-10-30 Soren Mikkelsen Giving a Service to a Patient
EP1819388A2 (en) * 2004-10-06 2007-08-22 Boehringer Ingelheim International GmbH Dispensing device, storage device and method for dispensing powder
GB0426780D0 (en) * 2004-12-07 2005-01-12 3M Innovative Properties Co Pressurized inhalation devices
GB0427853D0 (en) * 2004-12-20 2005-01-19 Glaxo Group Ltd Manifold for use in medicament dispenser
GB0427858D0 (en) * 2004-12-20 2005-01-19 Glaxo Group Ltd Manifold for use in medicament dispenser
GB0428169D0 (en) * 2004-12-23 2005-01-26 3M Innovative Properties Co Pressurized inhalation devices
FR2881111B1 (fr) * 2005-01-25 2010-07-30 Valois Sas Dispositif de distribution de produit fluide.
US8206360B2 (en) 2005-02-01 2012-06-26 Intelliject, Inc. Devices, systems and methods for medicament delivery
US8231573B2 (en) 2005-02-01 2012-07-31 Intelliject, Inc. Medicament delivery device having an electronic circuit system
US9022980B2 (en) 2005-02-01 2015-05-05 Kaleo, Inc. Medical injector simulation device
CN101111281B (zh) 2005-02-01 2013-02-06 因特利杰克特有限公司 用于药物递送的设备、系统和方法
US8361026B2 (en) 2005-02-01 2013-01-29 Intelliject, Inc. Apparatus and methods for self-administration of vaccines and other medicaments
BRPI0608087A2 (pt) * 2005-02-15 2009-11-10 Elan Pharma Int Ltd formulações injetáveis e em aerossol de benzodiazepina em nanopartìculas
AU2006225117A1 (en) * 2005-03-16 2006-09-21 Elan Pharma International Limited Nanoparticulate leukotriene receptor antagonist/corticosteroid formulations
CA2602341A1 (en) * 2005-03-23 2006-09-28 Elan Pharma International Limited Nanoparticulate corticosteroid and antihistamine formulations
GB0507711D0 (en) 2005-04-15 2005-05-25 Vectura Group Plc Improved blister piercing
UA95446C2 (ru) * 2005-05-04 2011-08-10 Іллюміджен Байосайєнсіз, Інк. Мутаци в генах oas1
WO2006125132A2 (en) 2005-05-18 2006-11-23 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
US8524735B2 (en) 2005-05-18 2013-09-03 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
EP1893273B1 (en) * 2005-05-18 2014-06-25 Nektar Therapeutics Adapter for use with aerosolization device for endobronchial therapy
TWI274641B (en) * 2005-08-30 2007-03-01 Rexon Ind Corp Ltd Cutting machine
DK1919954T3 (en) 2005-08-30 2017-01-30 Univ Miami Immune modulating tumor necrosis factor receptor (TNFR25) - agonists, antagonists and immunotoxins
BRPI0615819B8 (pt) 2005-09-14 2021-05-25 Mannkind Corp processo para preparar uma composição de distribuição de fármaco compreendendo um agente ativo e uma micropartícula fumaril dicetopiperazina cristalina.
US20090032427A1 (en) * 2005-09-29 2009-02-05 Nektar Therapeutics Receptacles and Kits, Such as for Dry Powder Packaging
US7713929B2 (en) 2006-04-12 2010-05-11 Biodel Inc. Rapid acting and long acting insulin combination formulations
US8084420B2 (en) * 2005-09-29 2011-12-27 Biodel Inc. Rapid acting and long acting insulin combination formulations
WO2007041481A1 (en) * 2005-09-29 2007-04-12 Biodel, Inc. Rapid acting and prolonged acting insulin preparations
AR058290A1 (es) * 2005-12-12 2008-01-30 Glaxo Group Ltd Dispensador de medicamento
AR058289A1 (es) 2005-12-12 2008-01-30 Glaxo Group Ltd Colector para ser usado en dispensador de medicamento
JP5096363B2 (ja) 2005-12-16 2012-12-12 ネクター セラピューティックス Ｇｌｐ−１のポリマ複合体
CN101389348A (zh) 2006-02-22 2009-03-18 曼金德公司 用于改善包含二酮哌嗪和活性剂的微粒的药物性质的方法
TWI501774B (zh) 2006-02-27 2015-10-01 Biogen Idec Inc 神經性病症之治療
US20100056440A1 (en) * 2006-03-01 2010-03-04 Biogen Idec Ma Inc. Compositions and methods for administering gdnf ligand family proteins
AU2011218649B8 (en) * 2006-03-29 2015-11-19 Kaleo, Inc. Devices, systems and methods for medicament delivery
DE102006016904A1 (de) * 2006-04-11 2007-10-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalator
DE102006016901A1 (de) * 2006-04-11 2007-10-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Mundstück für einen Inhalator
WO2007121256A2 (en) * 2006-04-12 2007-10-25 Biodel, Inc. Rapid acting and long acting insulin combination formulations
US7905229B2 (en) 2006-08-30 2011-03-15 Kurve Technology, Inc. Aerosol generating and delivery device
JP2010508069A (ja) * 2006-10-25 2010-03-18 ノバルティス アーゲー パウダー分散装置、その装置の製造方法および使用方法、その装置および他の装置に使用される構成要素
US8702836B2 (en) 2006-11-22 2014-04-22 Covaris, Inc. Methods and apparatus for treating samples with acoustic energy to form particles and particulates
WO2008091838A2 (en) 2007-01-22 2008-07-31 Intelliject, Inc. Medical injector with compliance tracking and monitoring
WO2008091355A2 (en) * 2007-01-24 2008-07-31 Breathe Pharmaceuticals, Inc. Drug transfer device
JP5583005B2 (ja) 2007-05-01 2014-09-03 バイオジェン・アイデック・エムエイ・インコーポレイテッド 血管新生を増大させるための組成物および方法
KR20100020511A (ko) * 2007-06-05 2010-02-22 파카 풀머네리 파마슈티칼즈, 인크. 폐로의 약물 전달을 위한 조성물, 이의 용도
US8496002B2 (en) * 2007-06-12 2013-07-30 Civitas Therapeutics, Inc. Powder inhaler devices
JP2010533181A (ja) * 2007-07-13 2010-10-21 アボツト・バイオテクノロジー・リミテツド ＴＮＦα阻害剤の肺投与のための方法及び組成物
EP2020249A1 (de) * 2007-08-01 2009-02-04 Boehringer Ingelheim Pharma GmbH & Co. KG Inhalator
WO2009020964A2 (en) * 2007-08-08 2009-02-12 Biogen Idec Ma Inc. Anti-neublastin antibodies and uses thereof
WO2009045553A1 (en) * 2007-10-05 2009-04-09 Barofold, Inc. High pressure treatment of aggregated interferons
US8785396B2 (en) 2007-10-24 2014-07-22 Mannkind Corporation Method and composition for treating migraines
WO2009055030A2 (en) * 2007-10-25 2009-04-30 Nektar Therapeutics Powder conditioning of unit dose drug packages
CA2711561A1 (en) * 2008-01-04 2009-07-16 Biodel, Inc. Insulin formulations for insulin release as a function of tissue glucose levels
TWI432198B (zh) 2008-02-26 2014-04-01 Parion Sciences Inc 多芳香族鈉通道阻斷劑
BRPI0910875B8 (pt) * 2008-03-27 2021-06-22 Mannkind Corp sistema de inalação de pó seco
USD994111S1 (en) 2008-05-12 2023-08-01 Kaleo, Inc. Medicament delivery device cover
US8021344B2 (en) 2008-07-28 2011-09-20 Intelliject, Inc. Medicament delivery device configured to produce an audible output
AU2009246217B2 (en) 2008-05-15 2013-01-10 Novartis Ag Pulmonary delivery of a fluoroquinolone
CA3086027C (en) 2008-06-13 2022-05-17 Mannkind Corporation A dry powder inhaler and system for drug delivery
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
MX2010014240A (es) 2008-06-20 2011-03-25 Mankind Corp Un metodo y aparato interactivo para perfilar en tiempo real esfuerzos de inhalacion.
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
EP2344200A2 (en) * 2008-09-19 2011-07-20 Nektar Therapeutics Modified therapeutics peptides, methods of their preparation and use
AU2009292643B2 (en) 2008-09-19 2016-02-18 Nektar Therapeutics Polymer conjugates of therapeutic peptides
EP2346509B1 (en) 2008-10-07 2020-05-13 Horizon Orphan LLC Inhalation of levofloxacin for reducing lung inflammation
US8815838B2 (en) 2008-10-07 2014-08-26 David C. Griffith Aerosol fluoroquinolone formulations for improved pharmacokinetics
GB0818476D0 (en) * 2008-10-09 2008-11-12 Vectura Delivery Device Ltd Inhaler
CA2742832A1 (en) * 2008-11-06 2010-05-14 Medispray Laboratories Pvt. Ltd Inhaler device
CA2744940A1 (en) 2008-12-10 2010-06-17 Paka Pulmonary Pharmaceuticals, Inc. Methods and compositions for delivery of medicaments to the lungs
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
GB0901520D0 (en) * 2009-01-30 2009-03-11 Vectura Delivery Devices Ltd Inhaler
US9060927B2 (en) * 2009-03-03 2015-06-23 Biodel Inc. Insulin formulations for rapid uptake
DK2405963T3 (da) 2009-03-11 2013-12-16 Mannkind Corp Apparat, system og fremgangsmåde til at måle modstand i en inhalator
EP3552603A1 (en) 2009-03-18 2019-10-16 Incarda Therapeutics, Inc. Unit doses, aerosols, kits, and methods for treating heart conditions by pulmonary administration
PT2410981T (pt) 2009-03-26 2017-05-25 Pulmatrix Inc Formulações em pó seco e métodos para tratar doenças pulmonares
WO2010115032A1 (en) 2009-04-01 2010-10-07 Promedior, Inc. Pulmonary and nasal delivery of serum amyloid p
JP5908397B2 (ja) 2009-06-09 2016-04-26 デフィルス、インコーポレイテッドＤｅｆｙｒｕｓ， Ｉｎｃ． 病原体感染を予防又は治療するためのインターフェロン投与
WO2010144789A2 (en) 2009-06-12 2010-12-16 Mannkind Corporation Diketopiperazine microparticles with defined specific surface areas
WO2010149280A1 (en) * 2009-06-25 2010-12-29 Boehringer Ingelheim Vetmedica Gmbh Inhaler
EP2454011A2 (en) 2009-07-13 2012-05-23 The University of North Carolina At Chapel Hill Engineered aerosol particles, and associated methods
NZ598484A (en) 2009-09-04 2014-02-28 Mpex Pharmaceuticals Inc Use of aerosolized levofloxacin for treating cystic fibrosis
WO2011035140A1 (en) 2009-09-18 2011-03-24 Paka Pulmonary Pharmaceuticals, Inc. Methods and compositions for delivery of contrast moieties to the lungs
US10166338B2 (en) 2009-09-21 2019-01-01 Novo Nordisk A/S Drug delivery system and device with cap function
WO2011056889A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
IN2012DN04857A (es) * 2009-12-23 2015-09-25 Map Pharmaceuticals Inc
KR20130117755A (ko) 2010-06-21 2013-10-28 맨카인드 코포레이션 건조 분말 약물 운반 시스템 및 방법
WO2011163518A1 (en) 2010-06-24 2011-12-29 Gilead Sciences, Inc. Pyrazolo [1, 5 -a] pyrimidines as antiviral agents
BR122020020745B8 (pt) 2010-07-22 2023-10-31 Gilead Sciences Inc Composto antiviral para o tratamento de infecções por paramyxoviridae e composição farmacêutica que o compreende
WO2012030647A1 (en) 2010-08-30 2012-03-08 Pulmatrix, Inc. Treatment of cystic fibrosis using calcium lactate, leucine and sodium chloride in a respiraple dry powder
CA2809666C (en) 2010-08-30 2020-09-22 Michael M. Lipp Dry powder formulations and methods for treating pulmonary diseases
TW201305185A (zh) 2010-09-13 2013-02-01 Gilead Sciences Inc 用於抗病毒治療之２’－氟取代之碳－核苷類似物
ES2899621T3 (es) 2010-09-29 2022-03-14 Pulmatrix Operating Co Inc Polvos secos catiónicos que comprenden sal de magnesio
CN107096014B (zh) 2010-09-29 2022-07-15 普马特里克斯营业公司 吸入用单价金属阳离子干粉剂
US8459121B2 (en) * 2010-10-28 2013-06-11 Covaris, Inc. Method and system for acoustically treating material
ES2645769T3 (es) 2011-01-05 2017-12-07 Hospira, Inc. Secado por pulverización de la vancomicina
JP6021117B2 (ja) 2011-01-31 2016-11-02 ジェノア ファーマシューティカルズ，インク． エアロゾルのピルフェニドンおよびピリドンアナログの化合物、および、その使用
WO2012119153A2 (en) * 2011-03-03 2012-09-07 Impel Neuropharma Inc. Nasal drug delivery device
WO2012135765A2 (en) 2011-04-01 2012-10-04 Mannkind Corporation Blister package for pharmaceutical cartridges
CA2754237A1 (en) 2011-05-27 2012-11-27 The Regents Of The University Of California Cyanoquinoline compounds having activity in correcting mutant-cftr processing and increasing ion transport and uses thereof
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
PT2723176T (pt) 2011-06-27 2017-07-18 Parion Sciences Inc Dipéptido química e metabolicamente estável que possui potente atividade bloqueadora do canal de sódio
US9004063B1 (en) * 2011-08-17 2015-04-14 Shane M. Guldbransen Portable oxygen inhaler device
LT5943B (lt) 2011-10-20 2013-06-25 Vilniaus Universitetas Plono elektrai laidaus permatomo grafeno sluoksnio gamybos būdas
MX2014004983A (es) 2011-10-24 2014-09-22 Mannkid Corp Metodos y composiciones para tratar dolor.
EP2790761B1 (en) 2011-12-16 2022-05-11 Novartis AG Passive powder aerosolization apparatus
EP2809780B1 (en) 2012-02-01 2018-05-02 Protalix Ltd. Dnase i polypeptides, polynucleotides encoding same, methods of producing dnase i and uses thereof in therapy
WO2013130767A1 (en) 2012-02-29 2013-09-06 Pulmatrix, Inc. Inhalable dry powders
MX355267B (es) * 2012-03-13 2018-04-12 Gilead Sciences Inc Análogos de carba-nucleósido 2´-sustituidos para tratamiento antivírico.
CN104619369B (zh) 2012-07-12 2018-01-30 曼金德公司 干粉药物输送系统和方法
EP2911690A1 (en) 2012-10-26 2015-09-02 MannKind Corporation Inhalable influenza vaccine compositions and methods
GB2526948A (en) 2012-12-27 2015-12-09 Kaleo Inc Systems for locating and interacting with medicament delivery devices
GB201301192D0 (en) 2013-01-23 2013-03-06 Vectura Delivery Devices Ltd A blister piercing element for a dry powder inhaler
SI2964199T1 (sl) 2013-03-04 2020-10-30 Besins Healthcare Luxembourg Sarl Suhi farmacevtski sestavki, ki obsegajo nanodelce aktivnega sredstva vezane na nosilne delce
CN104043104B (zh) 2013-03-15 2018-07-10 浙江创新生物有限公司 含盐酸万古霉素的喷雾干粉及其工业化制备方法
WO2014144895A1 (en) 2013-03-15 2014-09-18 Mannkind Corporation Microcrystalline diketopiperazine compositions and methods
MX2015013845A (es) 2013-04-01 2016-05-09 Pulmatrix Inc Polvos secos de tiotropio.
JP6491658B2 (ja) 2013-07-18 2019-03-27 マンカインド コーポレイション 熱安定性乾燥粉末医薬組成物及び方法
US10850289B2 (en) * 2013-07-22 2020-12-01 Inhalation Sciences Sweden Ab Apparatus and method for generating an aerosol
JP6799201B2 (ja) 2013-07-31 2020-12-16 アヴァリン ファーマ インク． エアロゾルチロシンキナーゼ阻害剤の化合物、及びその使用
US11446127B2 (en) 2013-08-05 2022-09-20 Mannkind Corporation Insufflation apparatus and methods
BR122022016461B1 (pt) 2013-08-20 2023-11-14 Boehringer Ingelheim Vetmedica Gmbh Inalador
EP3035885B1 (en) 2013-08-20 2019-12-25 Boehringer Ingelheim Vetmedica GmbH Inhaler
PT3035887T (pt) 2013-08-20 2020-04-02 Boehringer Ingelheim Vetmedica Gmbh Inalador
DE202013105715U1 (de) * 2013-08-22 2014-02-19 Sipnose Ltd. Vorrichtung zur Abgabe einer vorbestimmten Menge einer Substanz an eine natürliche Öffnung des Körpers
US11278682B2 (en) 2014-11-09 2022-03-22 Sipnose Ltd. Device and method for aerosolized delivery of substance to a natural orifice of the body
US11116914B2 (en) 2014-11-09 2021-09-14 Sipnose Ltd. Device and method for aerosolized delivering of substance to a natural orifice of the body
US11992604B2 (en) 2014-11-09 2024-05-28 Sipnose Ltd. Devices and methods for delivering a substance to a body cavity
US11471618B2 (en) 2014-11-09 2022-10-18 Sipnose Ltd. Adjustable dosing delivery and multi sectioned drug compartment
UA119050C2 (uk) 2013-11-11 2019-04-25 Ґілеад Саєнсиз, Інк. ПІРОЛО[1.2-f][1.2.4]ТРИАЗИНИ, ЯКІ ВИКОРИСТОВУЮТЬСЯ ДЛЯ ЛІКУВАННЯ РЕСПІРАТОРНО-СИНЦИТІАЛЬНИХ ВІРУСНИХ ІНФЕКЦІЙ
AU2015204558B2 (en) 2014-01-10 2020-04-30 Avalyn Pharma Inc. Aerosol pirfenidone and pyridone analog compounds and uses thereof
NO2709641T3 (es) * 2014-03-10 2018-05-12
WO2015148905A1 (en) 2014-03-28 2015-10-01 Mannkind Corporation Use of ultrarapid acting insulin
TWI678369B (zh) 2014-07-28 2019-12-01 美商基利科學股份有限公司 用於治療呼吸道合胞病毒感染之噻吩並［３,２-ｄ］嘧啶、呋喃並［３,２-ｄ］嘧啶及吡咯並［３,２-ｄ］嘧啶化合物類
TWI673283B (zh) 2014-08-21 2019-10-01 美商基利科學股份有限公司 ２’－氯胺基嘧啶酮及嘧啶二酮核苷類
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
US20170304459A1 (en) 2014-10-10 2017-10-26 Alnylam Pharmaceuticals, Inc. Methods and compositions for inhalation delivery of conjugated oligonucleotide
EP3244914A4 (en) 2015-01-16 2018-08-15 The J. David Gladstone Institutes Methods for treating tauopathy
AU2016243801B2 (en) 2015-04-02 2020-05-21 Hill-Rom Services Pte. Ltd. Manifold for respiratory device
KR101722667B1 (ko) * 2015-06-02 2017-04-04 주식회사 포에버 흑채 자동분사기
RU2727239C2 (ru) * 2016-01-19 2020-07-21 Новартис Аг Многодозовый ингалятор
IL260335B2 (en) 2016-02-01 2023-10-01 Incarda Therapeutics Inc Combining electronic monitoring with inhaled pharmacological therapy for the management of cardiac arrhythmia including atrial fibrillation
NL2017294B1 (en) 2016-08-05 2018-02-14 Univ Erasmus Med Ct Rotterdam Natural cryptic exon removal by pairs of antisense oligonucleotides.
WO2018116300A1 (en) * 2016-12-22 2018-06-28 Kamada Ltd. Dry powder formulations of alpha-1 antitrypsin
EP3570906A4 (en) 2017-01-17 2020-10-21 Kaleo, Inc. WIRELESS CONNECTIVITY AND EVENT DETECTION DRUG DELIVERY DEVICES
CA3060702A1 (en) 2017-05-10 2018-11-15 Incarda Therapeutics, Inc. Unit doses, aerosols, kits, and methods for treating heart conditions by pulmonary administration
KR102661786B1 (ko) 2017-05-22 2024-04-26 인스메드 인코포레이티드 글리코펩티드 유도체 화합물 및 이의 용도
WO2019003216A1 (en) * 2017-06-29 2019-01-03 Sipnose Ltd. ADJUSTABLE DOSE ADMINISTRATION AND MULTI-SECTION MEDICINE COMPARTMENT
WO2019183470A2 (en) 2018-03-22 2019-09-26 Incarda Therapeutics, Inc. A novel method to slow ventricular rate
US11929160B2 (en) 2018-07-16 2024-03-12 Kaleo, Inc. Medicament delivery devices with wireless connectivity and compliance detection
KR20220002600A (ko) 2019-04-29 2022-01-06 인스메드 인코포레이티드 트레프로스티닐 전구약물의 건조 분말 조성물 및 이의 사용 방법
US11020384B2 (en) 2019-08-01 2021-06-01 Incarda Therapeutics, Inc. Antiarrhythmic formulation
IL294032A (en) 2019-12-24 2022-08-01 Carna Biosciences Inc Compounds that regulate diacylglycerol kinase
TWI791193B (zh) 2020-02-18 2023-02-01 美商基利科學股份有限公司 抗病毒化合物
JP7429799B2 (ja) 2020-02-18 2024-02-08 ギリアード サイエンシーズ， インコーポレイテッド 抗ウイルス化合物
TW202245800A (zh) 2020-02-18 2022-12-01 美商基利科學股份有限公司 抗病毒化合物
TW202322824A (zh) 2020-02-18 2023-06-16 美商基利科學股份有限公司 抗病毒化合物
CR20220547A (es) 2020-05-01 2022-12-15 Gilead Sciences Inc Compuestos de 2,4-dioxopirimidina inhibidores de cd73
MX2022014536A (es) 2020-05-27 2023-03-03 Joozef Dispositivo para inhalar una sustancia.
PT3915408T (pt) * 2020-05-27 2023-02-20 Joozef Aparelho para inalação de uma substância
WO2022189662A1 (en) 2021-03-12 2022-09-15 Alvarius Pharmaceuticals Ltd. Compositions and methods for treating addictions comprising 5-meo-dmt
WO2022240897A1 (en) 2021-05-10 2022-11-17 Sepelo Therapeutics, Llc Pharmaceutical composition comprising delafloxacin for administration into the lung
CR20230585A (es) 2021-06-23 2024-02-19 Gilead Sciences Inc Compuestos Moduladores de Diacilglicerol Quinasa.
AU2022297367A1 (en) 2021-06-23 2023-12-07 Gilead Sciences, Inc. Diacylglyercol kinase modulating compounds
EP4359415A1 (en) 2021-06-23 2024-05-01 Gilead Sciences, Inc. Diacylglyercol kinase modulating compounds
AU2022298639A1 (en) 2021-06-23 2023-12-07 Gilead Sciences, Inc. Diacylglyercol kinase modulating compounds
WO2023028364A1 (en) 2021-08-27 2023-03-02 Sepelo Therapeutics, Llc Targeted compositions and uses therof
AU2022376954A1 (en) 2021-10-29 2024-05-02 Gilead Sciences, Inc. Cd73 compounds
WO2023150747A1 (en) 2022-02-07 2023-08-10 Insmed Incorporated Dry powder compositions of bedaquiline and salts and methods of use thereof
KR20240003477A (ko) * 2022-07-01 2024-01-09 주식회사 케이티앤지 인헤일러

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US478744A (en) * 1892-07-12 William james evans
US513189A (en) * 1894-01-23 Powder-blower
US2603216A (en) * 1952-07-15 Powder inhaler
US2307986A (en) * 1940-02-15 1943-01-12 Bolte Insufflator
US2533065A (en) * 1947-03-08 1950-12-05 George V Taplin Micropulverized therapeutic agents
US2570774A (en) * 1947-10-21 1951-10-09 Frank P C Davis Insufflator
US2549303A (en) * 1949-04-20 1951-04-17 Bristol Lab Inc Inhaler for crystalline pencilllin or the like
US3425600A (en) * 1966-08-11 1969-02-04 Abplanalp Robert H Pressurized powder dispensing device
US4069819A (en) * 1973-04-13 1978-01-24 Societa Farmaceutici S.P.A. Inhalation device
GB1479283A (en) * 1973-07-23 1977-07-13 Bespak Industries Ltd Inhaler for powdered medicament
IT1016489B (it) * 1974-03-18 1977-05-30 Isf Spa Inalatore
US3967761A (en) * 1974-04-08 1976-07-06 Southwest Research Institute System for injecting particulate material into the combustion chamber of a repetitive combustion coating apparatus
SU628930A1 (ru) * 1974-11-26 1978-10-25 Московский научно-исследовательский институт туберкулеза Устройство дл введени порошкообразного лекарственного вещества
GB1521000A (en) * 1975-06-13 1978-08-09 Syntex Puerto Rico Inc Inhalation device
US3994421A (en) * 1975-09-29 1976-11-30 American Cyanamid Company Unitary therapeutic aerosol dispenser
SE408265B (sv) * 1975-12-12 1979-06-05 Draco Ab Anordning for koldioxiddriven endosaerosol, avsedd for inhalering
NL7712041A (en) * 1977-11-01 1979-05-03 Handelmaatschappij Voorheen Be Suction equipment for powdery material - incorporates ejector type suction pump and cyclone type separator
EP0005585B1 (en) * 1978-05-03 1981-08-12 FISONS plc Inhalation device
SU1003926A1 (ru) * 1979-01-24 1983-03-15 Всесоюзный Научно-Исследовательский И Конструкторский Институт Автогенного Машиностроения Порошковый питатель
IT1116047B (it) * 1979-04-27 1986-02-10 Sigma Tau Ind Farmaceuti Dispositivo per la rapida inalazione di farmaci in polvere da parte di persone sofferenti di asma
WO1981001243A1 (en) * 1979-10-30 1981-05-14 Riker Laboratories Inc Breath actuated devices for administering powdered medicaments
LU85034A1 (fr) * 1982-10-08 1985-06-19 Glaxo Group Ltd Dispositifs en vue d'administrer des medicaments a des patients
GB8314308D0 (en) * 1983-05-24 1983-06-29 Matburn Holdings Ltd Medical administration devices
DE3345722A1 (de) * 1983-12-17 1985-06-27 Boehringer Ingelheim KG, 6507 Ingelheim Inhalator
FR2575678B1 (fr) * 1985-01-04 1988-06-03 Saint Gobain Vitrage Ejecteur pneumatique de poudre
US4719263A (en) 1985-05-10 1988-01-12 The B. F. Goodrich Company Antistatic plastic materials containing epihalohydrin polymers
BE905189A (fr) * 1985-07-30 1987-01-29 Glaxo Group Ltd Dispositif pour administrer des medicaments a des patients.
IT1222509B (it) * 1987-08-17 1990-09-05 Miat Spa Insufflatore per la somministrazione di farmaci sotto forma di polvere predosata in opercoli
IT1217890B (it) * 1988-06-22 1990-03-30 Chiesi Farma Spa Dispositivo per l'inalazione di aerosol dosati
US4984158A (en) * 1988-10-14 1991-01-08 Hillsman Dean Metered dose inhaler biofeedback training and evaluation system
DK479189D0 (da) * 1989-01-06 1989-09-28 Hans Gernot Schenk Inhalator
IT1228459B (it) * 1989-02-23 1991-06-19 Phidea S R L Inalatore con svuotamento regolare e completo della capsula.
IT1230313B (it) * 1989-07-07 1991-10-18 Somova Spa Inalatore per medicamenti in capsule.
DE3927170A1 (de) * 1989-08-17 1991-02-21 Boehringer Ingelheim Kg Inhalator
DE69108895T2 (de) 1990-01-05 1995-08-24 Goodrich Co B F Kettenverlängerte niedrige molekulargewichte aufzeigende polyoxirane zu elektrostatischen anwendungen.
US5201308A (en) * 1990-02-14 1993-04-13 Newhouse Michael T Powder inhaler
IT1243344B (it) * 1990-07-16 1994-06-10 Promo Pack Sa Inalatore plurimonodose per medicamenti in polvere
US5037912A (en) * 1990-07-26 1991-08-06 The Goodyear Tire & Rubber Company Polymerization of 1,3-butadiene to trans-1,4-polybutadiene with organolithium and alkali metal alkoxide
GB9016789D0 (en) 1990-07-31 1990-09-12 Lilly Industries Ltd Medicament administering devices
US5217004A (en) * 1990-12-13 1993-06-08 Tenax Corporation Inhalation actuated dispensing apparatus
DK0592540T3 (da) 1991-07-02 2000-06-26 Inhale Inc Fremgangsmåde og indretning til aflevering af aerosoliserede medikamenter
US5337740A (en) * 1991-08-01 1994-08-16 New England Pharmaceuticals, Inc. Inhalation devices
US5287850A (en) * 1991-08-20 1994-02-22 Habley Medical Technology Corporation Timing and velocity controlled powered pharmaceutical inhaler
GB9123953D0 (en) * 1991-11-12 1992-01-02 Minnesota Mining & Mfg Inhalation device
US5355872B1 (en) * 1992-03-04 1998-10-20 John H Riggs Low flow rate nebulizer apparatus and method of nebulization
US5186166A (en) * 1992-03-04 1993-02-16 Riggs John H Powder nebulizer apparatus and method of nebulization
KR0177265B1 (ko) * 1992-10-19 1999-04-01 미첼 알. 우드베리 건분말 흡입기
US5290278A (en) 1992-10-20 1994-03-01 Proclosure Inc. Method and apparatus for applying thermal energy to luminal tissue
US5348995A (en) 1993-03-29 1994-09-20 Ppg Industries, Inc. Amine-free internal antistatic agent
US5533502A (en) * 1993-05-28 1996-07-09 Vortran Medical Technology, Inc. Powder inhaler with aerosolization occurring within each individual powder receptacle
US5349947A (en) * 1993-07-15 1994-09-27 Newhouse Michael T Dry powder inhaler and process that explosively discharges a dose of powder and gas from a soft plastic pillow
US5388572A (en) * 1993-10-26 1995-02-14 Tenax Corporation (A Connecticut Corp.) Dry powder medicament inhalator having an inhalation-activated piston to aerosolize dose and deliver same
US5505194A (en) * 1994-03-23 1996-04-09 Abbott Laboratories Aerosol inhalation device having slideably and rotatably connected elliptical cylinder portions

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KR100399844B1 (ko) 2003-12-24
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KR970706033A (ko) 1997-11-03
KR100399845B1 (ko) 2003-09-29
DE69535725T2 (de) 2009-03-19
KR100400063B1 (ko) 2003-09-29
MY113727A (en) 2002-05-31
ZA957933B (en) 1996-08-02
US5785049A (en) 1998-07-28
EP1917992A3 (en) 2009-11-25
EP1917992A2 (en) 2008-05-07
US5740794A (en) 1998-04-21

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