AR005451A1 - Dispositivo de suministro de droga por via oral para la liberación de droga localizada en el tracto gastrointestinal y uso de dicho dispositivo - Google Patents

Dispositivo de suministro de droga por via oral para la liberación de droga localizada en el tracto gastrointestinal y uso de dicho dispositivo

Info

Publication number
AR005451A1
AR005451A1 ARP970100125A ARP970100125A AR005451A1 AR 005451 A1 AR005451 A1 AR 005451A1 AR P970100125 A ARP970100125 A AR P970100125A AR P970100125 A ARP970100125 A AR P970100125A AR 005451 A1 AR005451 A1 AR 005451A1
Authority
AR
Argentina
Prior art keywords
drug
gastrointestinal tract
release
insoluble
center
Prior art date
Application number
ARP970100125A
Other languages
English (en)
Original Assignee
Dexcel Pharma Technologies Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dexcel Pharma Technologies Ltd filed Critical Dexcel Pharma Technologies Ltd
Publication of AR005451A1 publication Critical patent/AR005451A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)

Abstract

Se proporciona un sistema de suminisstro gastrointestinal. El sistema comprende una droga en combinación con un material de centro, estando el centrorodeado por un material de cubierta insoluble en agua o relativamente insoluble en agua, en elcual se fija material de particulado insoluble en agua. Cuandoel dispositivo de suministro entra en el tracto gastrointestinal, la materia de particulado absorbe líquido, formando de esa manera canales que interconectanel centro que contiene ladroga con el exterior del dispositivo de suministro. Estos canales permiten la liberación de la droga desde el centro dentro deltracto gastrointestinal. Controlando los parámetros en el dispositivo, como el material del centro, el materialportador en l a cubierta, y la materia departiculado se puede controlar cuidadosamente el lugar de liberación de la droga. Así la invención está también dirigida a un método de uso deldispositivo para el tratamiento de enfermedades, mediante laliberación de drogas en el tracto gastrointestinal en una forma que depende del lugar y deltiempo.
ARP970100125A 1996-01-18 1997-01-13 Dispositivo de suministro de droga por via oral para la liberación de droga localizada en el tracto gastrointestinal y uso de dicho dispositivo AR005451A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/588,247 US5840332A (en) 1996-01-18 1996-01-18 Gastrointestinal drug delivery system

Publications (1)

Publication Number Publication Date
AR005451A1 true AR005451A1 (es) 1999-06-23

Family

ID=24353076

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP970100125A AR005451A1 (es) 1996-01-18 1997-01-13 Dispositivo de suministro de droga por via oral para la liberación de droga localizada en el tracto gastrointestinal y uso de dicho dispositivo

Country Status (16)

Country Link
US (1) US5840332A (es)
EP (1) EP0877604B1 (es)
JP (1) JP4165905B2 (es)
CN (1) CN1208343A (es)
AR (1) AR005451A1 (es)
AT (1) ATE291417T1 (es)
AU (1) AU713722B2 (es)
CZ (1) CZ295932B6 (es)
DE (1) DE69732830T2 (es)
ES (1) ES2241031T3 (es)
IL (1) IL125042A (es)
MY (1) MY133883A (es)
NZ (1) NZ324808A (es)
WO (1) WO1997025979A1 (es)
YU (1) YU1497A (es)
ZA (1) ZA97405B (es)

Families Citing this family (161)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE226090T1 (de) 1994-04-22 2002-11-15 Yamanouchi Pharma Co Ltd Kolon-spezifisches arzneistofffreisetzungssystem
DE69631981T2 (de) * 1995-09-21 2005-04-14 Pharma Pass Ii Llc, Irvine Lansoprazolhaltige Arzneizusammensetzung und Herstellungsverfahren
US6231888B1 (en) 1996-01-18 2001-05-15 Perio Products Ltd. Local delivery of non steroidal anti inflammatory drugs (NSAIDS) to the colon as a treatment for colonic polyps
KR20000029784A (ko) * 1996-08-02 2000-05-25 나까도미 히로다카 경구제제용캡슐과경구캡슐제제
SE9604751D0 (sv) * 1996-12-20 1996-12-20 Astra Ab New therapy
GB9720797D0 (en) * 1997-09-30 1997-12-03 Rhodes John Pharmaceutical composition for the treatment of inflammatory bowel disease and irritable bowel syndrome
CA2305762C (en) * 1997-10-09 2006-09-26 Perio Products Ltd. Delayed total release gastrointestinal drug delivery system
US6350470B1 (en) * 1998-04-29 2002-02-26 Cima Labs Inc. Effervescent drug delivery system for oral administration
DK1079810T3 (da) * 1998-04-22 2004-11-01 Glycologic Ltd Oralt administrerbare sammensætninger, der omfatter kationtværbundet polysaccharid og en polymer, som er fordöjelig i den nedre mave-tarmkanal
US7022683B1 (en) 1998-05-13 2006-04-04 Carrington Laboratories, Inc. Pharmacological compositions comprising pectins having high molecular weights and low degrees of methoxylation
CN1195500C (zh) 1998-05-18 2005-04-06 武田药品工业株式会社 可口腔崩解的片剂
SI1077722T1 (sl) 1998-05-22 2007-02-28 Ottawa Health Research Inst Metode in produkti za induciranje sluznicne imunosti
SI1100469T1 (es) 1998-07-28 2005-08-31 Takeda Pharmaceutical
ATE321538T1 (de) 1998-08-12 2006-04-15 Altana Pharma Ag Orale darreichungsform für pyridin-2- ylmethylsulfinyl-1h-benzimidazole
US6514525B2 (en) 1998-09-10 2003-02-04 Norton Healthcare Ltd Anti-inflammatory pharmaceutical formulations
US6387410B1 (en) 1998-09-10 2002-05-14 Norton Healthcare Ltd Anti-inflammatory pharmaceutical formulations
US6645192B2 (en) * 1998-09-30 2003-11-11 Ivy Animal Health, Inc. Pellet implant system for immediate and delayed release of antiparasitic drug
US6531152B1 (en) * 1998-09-30 2003-03-11 Dexcel Pharma Technologies Ltd. Immediate release gastrointestinal drug delivery system
US20090149479A1 (en) * 1998-11-02 2009-06-11 Elan Pharma International Limited Dosing regimen
US20060240105A1 (en) * 1998-11-02 2006-10-26 Elan Corporation, Plc Multiparticulate modified release composition
CA2653839A1 (en) * 1998-11-02 2000-05-11 John G. Devane Multiparticulate modified release composition
DZ2937A1 (fr) * 1998-11-12 2004-03-15 Smithkline Beecham Plc Compositions nouvelles de sensibilidants à l'insuline.
SA99191255B1 (ar) 1998-11-30 2006-11-25 جي دي سيرل اند كو مركبات سيليكوكسيب celecoxib
US6723342B1 (en) 1999-02-08 2004-04-20 Fmc Corporation Edible coating composition
US6432448B1 (en) * 1999-02-08 2002-08-13 Fmc Corporation Edible coating composition
US6351665B1 (en) 1999-05-07 2002-02-26 Kenneth L Koch Method and apparatus for evaluating myoelectric signals and identifying artifact
US6632451B2 (en) * 1999-06-04 2003-10-14 Dexcel Pharma Technologies Ltd. Delayed total release two pulse gastrointestinal drug delivery system
AU5108200A (en) 1999-06-09 2000-12-28 Mochida Pharmaceutical Co., Ltd. System for release in lower digestive tract
US8895064B2 (en) 1999-06-14 2014-11-25 Cosmo Technologies Limited Controlled release and taste masking oral pharmaceutical composition
CN1173695C (zh) 1999-06-14 2004-11-03 科斯默股份公司 控制释放与掩蔽味道的口服药物组合物
SE9902386D0 (sv) * 1999-06-22 1999-06-22 Astra Ab New formulation
EP1064938A1 (en) * 1999-06-28 2001-01-03 Sanofi-Synthelabo Pharmaceutical dosage forms for controlled release producing at least a timed pulse
US20040258750A1 (en) * 1999-06-28 2004-12-23 Gerard Alaux Timed dual release dosage forms comprising a short acting hypnotic or a salt thereof
CN1162183C (zh) * 1999-08-09 2004-08-18 大日本制药株式会社 含有脱乙酰壳多糖粉末的固体制剂及其生产工艺
US6500462B1 (en) 1999-10-29 2002-12-31 Fmc Corporation Edible MCC/PGA coating composition
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
ES2374717T3 (es) 1999-10-29 2012-02-21 Euro-Celtique S.A. Formulaciones de hidrocodona de liberación controlada.
IL133196A0 (en) * 1999-11-29 2001-03-19 Yissum Res Dev Co Gastroretentive controlled release pharmaceutical dosage forms
US7771746B2 (en) * 1999-12-03 2010-08-10 Polichem Sa Methods for making sustained-release pharmaceutical compositions of ergot alkaloids having improved bioavailability and compositions thereof
DE19961897A1 (de) * 1999-12-20 2001-06-28 Basf Ag Verwendung eines Filmüberzuges als geschmacksmaskierendes Coating von pharmazeutischen Darreichungsformen
JP2003518487A (ja) 1999-12-23 2003-06-10 ファイザー・プロダクツ・インク ヒドロゲル駆動型積層薬物製剤
YU35302A (sh) * 1999-12-23 2005-03-15 Pfizer Products Inc. Dozirani oblik leka sa inicijalnim hidrogelom
US6451345B1 (en) * 2000-01-20 2002-09-17 Eurand Pharmaceuticals Ltd. Functional coating of linezolid microcapsules for taste-masking and associated formulation for oral administration
AU767812B2 (en) 2000-02-04 2003-11-27 Depomed, Inc. Shell-and-core dosage form approaching zero-order drug release
IN192159B (es) * 2000-05-15 2004-02-28 Ranbaxy Lab Ltd
CN1141974C (zh) 2000-06-07 2004-03-17 张昊 结肠定位释放的口服生物制剂
CN1285333C (zh) * 2000-06-07 2006-11-22 张昊 结肠定位释放的口服制剂及其制备方法
IL137431A0 (en) 2000-07-20 2001-07-24 Slo Flo Ltd A new slow release device for controlled delivery of liquid material
KR100411195B1 (ko) * 2000-09-26 2003-12-18 한국화학연구원 케토롤락 트로메타민이 함유된 서방형 펠렛
JP2004512354A (ja) 2000-10-30 2004-04-22 ユーロ−セルティーク，エス．エイ． ヒドロコドン放出制御製剤
AU2002225763A1 (en) 2000-11-28 2002-06-11 Fmc Corporation Edible pga(propylene glycol alginate) coating composition
US6932861B2 (en) * 2000-11-28 2005-08-23 Fmc Corporation Edible PGA coating composition
US7494669B2 (en) 2001-02-28 2009-02-24 Carrington Laboratories, Inc. Delivery of physiological agents with in-situ gels comprising anionic polysaccharides
US6777000B2 (en) 2001-02-28 2004-08-17 Carrington Laboratories, Inc. In-situ gel formation of pectin
US7316819B2 (en) * 2001-03-08 2008-01-08 Unigene Laboratories, Inc. Oral peptide pharmaceutical dosage form and method of production
EP1395224A4 (en) * 2001-05-22 2005-10-26 Euro Celtique INVIOLABLE ORAL DOSAGE FORM
WO2003002100A1 (en) * 2001-06-26 2003-01-09 Farrell John J Tamper-proof narcotic delivery system
US20030104052A1 (en) * 2001-10-25 2003-06-05 Bret Berner Gastric retentive oral dosage form with restricted drug release in the lower gastrointestinal tract
US20030091630A1 (en) * 2001-10-25 2003-05-15 Jenny Louie-Helm Formulation of an erodible, gastric retentive oral dosage form using in vitro disintegration test data
US20030152622A1 (en) * 2001-10-25 2003-08-14 Jenny Louie-Helm Formulation of an erodible, gastric retentive oral diuretic
CA2409552A1 (en) * 2001-10-25 2003-04-25 Depomed, Inc. Gastric retentive oral dosage form with restricted drug release in the lower gastrointestinal tract
US7045549B2 (en) 2001-11-08 2006-05-16 The Board Of Trustees Of The Leland Stanford Jr. University Treatment of symptoms associated with irritable bowel syndrome
US7550156B2 (en) 2001-11-23 2009-06-23 Rohm And Haas Company Optimised pellet formulations
BR0215262A (pt) * 2001-12-20 2004-12-28 Pharmacia Corp Formas de dosagem com liberação sustentada de ordem zero e processo para a fabricação das mesmas
AU2003212215B9 (en) * 2002-01-15 2008-02-21 Bio Life Science Forschungs Und Entwicklungsges M.B.H. Oral vaccination
EP1327450B1 (de) * 2002-01-15 2007-08-15 Bio Life Science Forschungs- und Entwicklungsges.m.b.H. Orale Vakzinierung mit nackten Tumor-Antigen-Mimotopen
US20040071780A1 (en) * 2002-01-16 2004-04-15 Lillard James W. PACE-A microspheres for delivery of antigens
US20060073204A1 (en) * 2002-03-05 2006-04-06 Sandhya Goyal Modified release oral pharmaceutical composition
US20040156844A1 (en) * 2002-05-22 2004-08-12 Curtis Wright Tamper resistant oral dosage form
US6986901B2 (en) 2002-07-15 2006-01-17 Warner-Lambert Company Llc Gastrointestinal compositions
US7985422B2 (en) * 2002-08-05 2011-07-26 Torrent Pharmaceuticals Limited Dosage form
FR2843872B1 (fr) 2002-08-29 2005-08-19 C T M Ct De Transfert Des Micr Dispositif de localisation equipant une capsule intestinale
US20040062778A1 (en) * 2002-09-26 2004-04-01 Adi Shefer Surface dissolution and/or bulk erosion controlled release compositions and devices
US6703044B1 (en) 2002-10-25 2004-03-09 Dexcel Pharma Tech, Ltd Venlafaxine formulations
EP1558211A2 (en) * 2002-10-30 2005-08-03 Pharmacia Corporation Oral extended release tablets and methods of making and using the same
US9561182B2 (en) 2003-08-22 2017-02-07 Cure Pharmaceutical Corporation Edible films for administration of medicaments to animals, methods for their manufacture and methods for their use for the treatment of animals
CN1322865C (zh) * 2002-11-14 2007-06-27 北京东方凯恩医药科技有限公司 用于治疗菌痢的口服结肠定位给药组合物
US20040096497A1 (en) * 2002-11-19 2004-05-20 Ponder Garratt W. Methods of providing controlled-release pharmaceutical compositions and controlled-release pharmaceutical compositions
US8519008B2 (en) 2003-01-22 2013-08-27 Purina Animal Nutrition Llc Method and composition for improving the health of young monogastric mammals
US20050147663A1 (en) * 2003-07-17 2005-07-07 Mohan Mailatur S. Method of treatment for improved bioavailability
RU2375048C2 (ru) * 2003-07-17 2009-12-10 Д-Р Редди'С Лабораторис Инк. Фармацевтическая композиция с набухающим покрытием
US7737133B2 (en) 2003-09-03 2010-06-15 Agi Therapeutics Ltd. Formulations and methods of treating inflammatory bowel disease
US7825106B2 (en) 2003-09-03 2010-11-02 Agi Therapeutics Ltd. Modified release formulations and methods of treating inflammatory bowel disease
MXPA06003100A (es) * 2003-09-19 2006-06-20 Penwest Pharmaceuticals Co Formas de dosis de liberacion retardada.
PL1682537T3 (pl) 2003-11-05 2012-09-28 Sarcode Bioscience Inc Modulatory adhezji komórkowej
US8734850B2 (en) * 2003-11-25 2014-05-27 Flamel Technologies Oral medicinal product with modified release of at least one active principle in multimicrocapsular form
MXPA06008855A (es) * 2004-02-03 2007-04-17 Univ California Metodos para tratar sindrome de intestino irritable.
AU2005247195A1 (en) * 2004-05-27 2005-12-08 Dexcel Pharma Technologies Ltd Localized controlled absorption of statins in the gastrointestinal tract for achieving high blood levels of statins
US20090196889A1 (en) * 2004-11-22 2009-08-06 Dexcel Pharma Technologies Ltd. Controlled absorption of statins in the intestine
AU2005305460B2 (en) * 2004-11-22 2011-04-21 Dexcel Pharma Technologies Ltd. Stable atorvastatin formulations
FR2878159B1 (fr) * 2004-11-24 2008-10-17 Flamel Technologies Sa Medicament oral a liberation modifiee d'au moins un principe actif sous forme multimicrocapsulaire
WO2006063078A2 (en) * 2004-12-08 2006-06-15 Elan Corporation, Plc Topiramate pharmaceuticals composition
US8481565B2 (en) 2004-12-27 2013-07-09 Eisai R&D Management Co., Ltd. Method for stabilizing anti-dementia drug
US20060159753A1 (en) * 2004-12-27 2006-07-20 Eisai Co. Ltd. Matrix type sustained-release preparation containing basic drug or salt thereof
BRPI0606395A2 (pt) * 2005-01-05 2009-06-23 Univ Texas conjugados para ambas imagem e radioquimioterapia: composição, fabricação e aplicações
ES2522895T3 (es) 2005-03-03 2014-11-19 Alfa Wassermann S.P.A. Nuevas formas polimorfas de rifaximina, procedimientos para su producción y uso de las mismas en preparados medicinales
ITBO20050123A1 (it) * 2005-03-07 2005-06-06 Alfa Wassermann Spa Formulazioni farmaceutiche gastroresistenti contenenti rifaximina
WO2006123364A2 (en) * 2005-03-14 2006-11-23 Sun Pharmaceutical Industries Limited Oral drug delivery system providing a coating comprising both a cellulose and a methacrylic acid derivative
AU2006228525A1 (en) * 2005-03-28 2006-10-05 Dexcel Pharma Technologies Ltd. Controlled absorption of statins in the intestine
US20080069870A1 (en) * 2005-04-12 2008-03-20 Elan Corporation Pic Controlled Release Compositions Comprising a Cephalosporin for the Treatment of a Bacterial Infection
JP5794721B2 (ja) 2005-05-17 2015-10-14 サーコード バイオサイエンス インコーポレイテッド 眼障害の治療のための組成物および方法
US20060280795A1 (en) * 2005-06-08 2006-12-14 Dexcel Pharma Technologies, Ltd. Specific time-delayed burst profile delivery system
US8778395B2 (en) * 2005-08-11 2014-07-15 Andrx Labs, Llc Diltiazem controlled release formulation and method of manufacture
US20070082027A1 (en) * 2005-10-07 2007-04-12 Aimutis William R Jr Compositions and methods for reducing food intake and controlling weight
US20070082029A1 (en) * 2005-10-07 2007-04-12 Aimutis William R Fiber satiety compositions
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
WO2008003043A2 (en) 2006-06-28 2008-01-03 Surmodics, Inc. Combination degradable and non-degradable matrices for active agent delivery
MY149863A (en) 2006-08-03 2013-10-31 Nitec Pharma Ag Delayed-release glucocorticoid treatment of rheumatoid disease
US8889184B2 (en) * 2006-09-07 2014-11-18 Losan Pharma Gmbh Particulate form of a pharmaceutical composition which is easy to swallow
WO2008044236A2 (en) * 2006-10-10 2008-04-17 Dexcel Pharma Technologies Ltd. Improved release of statins in the intestine
US8273376B2 (en) 2006-11-17 2012-09-25 Da Volterra Colonic delivery of metallo-dependent enzymes
BRPI0719319A2 (pt) * 2006-11-17 2014-02-04 Da Volterra Liberação colônica usando contas de zn/pectina com um revestimento de eudragit
US20080260823A1 (en) * 2007-04-20 2008-10-23 Sciele Pharma, Inc. Orally disintegrating tablet comprising glycopyrrolate for treating sialorrhea
US20090036414A1 (en) * 2007-08-02 2009-02-05 Mutual Pharmaceutical Company, Inc. Mesalamine Formulations
WO2009037264A2 (en) * 2007-09-17 2009-03-26 Da Volterra Colonic delivery of antimicrobial agents
AU2008317473B2 (en) 2007-10-19 2014-07-17 Bausch + Lomb Ireland Limited Compositions and methods for treatment of diabetic retinopathy
US20090143343A1 (en) 2007-11-13 2009-06-04 Meritage Pharma, Inc. Compositions for the treatment of inflammation of the gastrointestinal tract
JP2011503073A (ja) 2007-11-13 2011-01-27 メリテイジ ファーマ，インク． コルチコステロイド組成物
US20100216754A1 (en) * 2007-11-13 2010-08-26 Meritage Pharma, Inc. Compositions for the treatment of inflammation of the gastrointestinal tract
US20090169622A1 (en) * 2007-12-27 2009-07-02 Roxane Laboratories, Inc. Delayed-release oral pharmaceutical composition for treatment of colonic disorders
WO2009139817A2 (en) 2008-04-15 2009-11-19 Sarcode Corporation Crystalline pharmaceutical and methods of preparation and use thereof
EP2179727B1 (en) * 2008-10-27 2013-05-29 Roquette Freres Water insoluble polymer: modified starch derivative-based film coatings for colon targeting
NZ582836A (en) * 2009-01-30 2011-06-30 Nitec Pharma Ag Delayed-release glucocorticoid treatment of rheumatoid arthritis by improving signs and symptoms, showing major or complete clinical response and by preventing from joint damage
US8945616B2 (en) * 2009-02-17 2015-02-03 Mylan Pharmaceuticals Inc. Controlled release budesonide minitablets
US8945615B2 (en) * 2009-02-17 2015-02-03 Mylan Pharmaceuticals Inc. Controlled release budesonide minitablets
BRPI1009823A2 (pt) * 2009-03-13 2019-09-24 Da Volterra Assistance Publique Hopitaux De Paris E Univ Paris Diderot Paris 7 "composição compreendendo um sistema de dispensação de droga, conjunto de uma primeira e uma segunda composição, e, kit."
WO2010144865A2 (en) * 2009-06-12 2010-12-16 Meritage Pharma, Inc. Methods for treating gastrointestinal disorders
WO2011050175A1 (en) 2009-10-21 2011-04-28 Sarcode Corporation Crystalline pharmaceutical and methods of preparation and use thereof
IT1398550B1 (it) 2010-03-05 2013-03-01 Alfa Wassermann Spa Formulazioni comprendenti rifaximina utili per ottenere un effetto prolungato nel tempo
US20130164380A1 (en) 2010-06-17 2013-06-27 Actogenix Nv Compositions and methods for treating inflammatory conditions
EP2672981B1 (en) 2011-02-11 2018-03-28 Zx Pharma, Llc Multiparticulate l-menthol formulations and related methods
US8911780B2 (en) 2011-02-11 2014-12-16 Zx Pharma, Llc Multiparticulate L-menthol formulations and related methods
US8808736B2 (en) 2011-02-11 2014-08-19 Zx Pharma, Llc Enteric coated multiparticulate controlled release peppermint oil composition and related methods
JP6121990B2 (ja) 2011-05-13 2017-04-26 イービー アイピー ハイブリタブス ビー．ブイ． 薬物送達システム
ITBO20110461A1 (it) 2011-07-29 2013-01-30 Alfa Wassermann Spa Composizioni farmaceutiche comprendenti rifaximina, processi per la loro preparazione e loro uso nel trattamento di infezioni vaginali.
US10154964B2 (en) 2011-09-07 2018-12-18 Cosmo Technologies Limited Controlled release and taste masking oral pharmaceutical composition
ITBO20120368A1 (it) 2012-07-06 2014-01-07 Alfa Wassermann Spa Composizioni comprendenti rifaximina e amminoacidi, cristalli di rifaximina derivanti da tali composizioni e loro uso.
AU2013295706A1 (en) 2012-07-25 2015-02-19 Sarcode Bioscience Inc. LFA-1 inhibitor and polymorph thereof
US20140066837A1 (en) 2012-07-26 2014-03-06 Ronald L. Moy Skin care compositions and methods
US9289418B2 (en) 2013-03-15 2016-03-22 Cedars-Sinai Medical Center Methods of diagnosis, selection, and treatment of diseases and conditions caused by or associated with methanogens
AU2014239164B2 (en) 2013-03-15 2018-12-06 Cedars-Sinai Medical Center Methods of diagnosis, selection, and treatment of diseases and conditions caused by or associated with methanogens
LT2978416T (lt) * 2013-03-26 2016-12-12 Lipid Therapeutics Gmbh Farmacinė kompozicija, apimanti fosfatidilcholiną, skirtą opinio kolito gydymui
EP2988824B1 (en) 2013-04-23 2018-11-07 Zx Pharma, Llc Enteric coated multiparticulate composition with proteinaceous subcoat
US9938298B2 (en) 2014-05-12 2018-04-10 Alfa Wassermann S.P.A. Solvated crystal form of rifaximin, production, compositions and uses thereof
BR122021018078B1 (pt) 2014-06-11 2022-02-08 Massachusetts Institute Of Technology Artigo e estrutura de residência gástrica
US20170266112A1 (en) 2014-06-11 2017-09-21 Massachusetts Institute Of Technology Residence structures and related methods
RU2697851C2 (ru) 2014-08-13 2019-08-21 Седарс-Синаи Медикал Сентер Антиметаногенные композиции и их применение
US20160158174A1 (en) * 2014-12-09 2016-06-09 Intercontinental Great Brands Llc Enteric-Coated Functional Food Ingredients And Methods For Making The Enteric-Coated Functional Food Ingredients
EP3277274B1 (en) 2015-04-01 2024-06-12 Cedars-Sinai Medical Center Anti-methanogenic lovastatin analogs or derivatives and uses thereof
JP2018515476A (ja) 2015-05-01 2018-06-14 マサチューセッツ インスティテュート オブ テクノロジー 誘発性形状記憶誘導デバイス
US11576859B2 (en) 2015-10-23 2023-02-14 Lyndra Therapeutics, Inc. Gastric residence systems for sustained release of therapeutic agents and methods of use thereof
CA3007633A1 (en) 2015-12-08 2017-06-15 Lyndra, Inc. Geometric configurations for gastric residence systems
WO2017189422A1 (en) * 2016-04-25 2017-11-02 Gelesis, Llc. Method for treating constipation
BR112018072795A2 (pt) 2016-05-06 2019-04-30 Physician's Seal, LLC composição de valeriana e métodos relacionados
JP6780412B2 (ja) * 2016-09-28 2020-11-04 ライオン株式会社 コーティング組成物ならびにコーティング製剤及びその製造方法
CA3038557A1 (en) 2016-09-30 2018-04-05 Lyndra, Inc. Gastric residence systems for sustained delivery of adamantane-class drugs
US10940113B2 (en) * 2017-02-24 2021-03-09 Medical And Pharmaceutical Industry Technology And Development Center Pharmaceutical composition for colon targeting, method for treating a colon-related disease using the same and preparation method thereof
CN110996906A (zh) * 2017-06-09 2020-04-10 林德拉有限公司 具有调节释放速度的膜的胃驻留系统
CN112384245A (zh) * 2018-05-08 2021-02-19 J·M·普罗茨 用于药物靶向递送的方法和组合物
US11904033B2 (en) 2020-10-19 2024-02-20 The Procter & Gamble Company Oral care article comprising a hydrophobic delivery carrier and solid hydrophilic particles comprising a bleaching agent
CN114224860B (zh) * 2021-11-06 2023-04-28 山东润德生物科技有限公司 氨基葡萄糖钙片制剂及其制备方法与应用

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3845770A (en) * 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
US3921636A (en) * 1973-01-15 1975-11-25 Alza Corp Novel drug delivery device
US3916899A (en) * 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway
SE7504049L (sv) * 1975-04-09 1976-10-10 Haessle Ab Colonpreparation
DE2717707C3 (de) * 1977-04-21 1979-11-22 Chephasaar Chemisch-Pharmazeutische Fabrik Gmbh, 6670 St Ingbert Karamellisierte Lactulose
US4327725A (en) * 1980-11-25 1982-05-04 Alza Corporation Osmotic device with hydrogel driving member
JPS57197214A (en) * 1981-05-29 1982-12-03 Tanabe Seiyaku Co Ltd Rapid-releasing microcapsule and its preparation
JPS5858145A (ja) * 1981-10-05 1983-04-06 Tanabe Seiyaku Co Ltd 速放性マイクロカプセル
JPS5867616A (ja) * 1981-10-15 1983-04-22 Tanabe Seiyaku Co Ltd 腸溶性マイクロカプセル
JPS59193831A (ja) * 1983-04-18 1984-11-02 Sankyo Co Ltd 腸溶性製剤の製造法
US4503030A (en) * 1983-06-06 1985-03-05 Alza Corporation Device for delivering drug to certain pH environments
US4627850A (en) * 1983-11-02 1986-12-09 Alza Corporation Osmotic capsule
US4863744A (en) * 1984-09-17 1989-09-05 Alza Corporation Intestine drug delivery
US4610870A (en) * 1984-10-05 1986-09-09 E. R. Squibb & Sons, Inc. Controlled release formulation
US4668517A (en) * 1985-04-04 1987-05-26 Norwich Eaton Pharmaceuticals, Inc. Furazolidone dosage form
GB8518301D0 (en) * 1985-07-19 1985-08-29 Fujisawa Pharmaceutical Co Hydrodynamically explosive systems
ES2022454B3 (es) * 1986-06-17 1991-12-01 Recordati Ind Chimica E Farm S P A Sistema terapeutico para la liberacion controlada de drogas.
IL85538A (en) * 1987-02-27 1991-09-16 Lilly Co Eli Sustained release matrix tablet formulations containing hydrophilic and enteric polymers
GB8705083D0 (en) * 1987-03-04 1987-04-08 Euro Celtique Sa Spheroids
US4904474A (en) * 1988-01-25 1990-02-27 Alza Corporation Delivery of drug to colon by oral disage form
DK110188D0 (da) * 1988-03-02 1988-03-02 Claus Selch Larsen High molecular weight prodrug derivatives of antiinflammatory drugs
US4857331A (en) * 1988-03-31 1989-08-15 Warner-Lambert Company Sugarless pectin delivery system
IT1219942B (it) * 1988-05-13 1990-05-24 Fidia Farmaceutici Esteri polisaccaridici
IT1219587B (it) * 1988-05-13 1990-05-18 Fidia Farmaceutici Polisaccaridi carbossiilici autoreticolati
US4925677A (en) * 1988-08-31 1990-05-15 Theratech, Inc. Biodegradable hydrogel matrices for the controlled release of pharmacologically active agents
US5133974A (en) * 1989-05-05 1992-07-28 Kv Pharmaceutical Company Extended release pharmaceutical formulations
US4983401A (en) * 1989-05-22 1991-01-08 Kinaform Technology, Inc. Sustained release pharmaceutical preparations having pH controlled membrane coatings
GB8926639D0 (en) * 1989-11-24 1990-01-17 Agricultural & Food Res Delayed release formulations
DE4006521A1 (de) * 1990-03-02 1991-09-05 Bayer Ag Zuckerhaltige polymere zur umhuellung und einbettung von arzneistoffen
IT1246382B (it) * 1990-04-17 1994-11-18 Eurand Int Metodo per la cessione mirata e controllata di farmaci nell'intestino e particolarmente nel colon
SE9002339L (sv) * 1990-07-04 1992-01-05 Kabi Pharmacia Ab Terapeutisk komposition och foerfarande foer dess framstaellning
US5422121A (en) * 1990-11-14 1995-06-06 Rohm Gmbh Oral dosage unit form
DE9015551U1 (de) * 1990-11-14 1992-03-12 Röhm GmbH, 6100 Darmstadt Orale Arzneiform und Überzugsmittel, enthaltend ein im Colon abbaubares Polysaccarid
NZ242065A (en) * 1991-03-26 1996-06-25 Csl Ltd Delayed release implant having a degradable or rupturable polymeric coating
DE4200821A1 (de) * 1992-01-15 1993-07-22 Bayer Ag Geschmacksmaskierte pharmazeutische mittel
DE4236025A1 (de) * 1992-10-24 1994-04-28 Merck Patent Gmbh Orale Arzneiformen
FR2698560B1 (fr) * 1992-11-30 1995-02-03 Virbac Laboratoires Principes actifs pulvérulents stabilisés, compositions les contenant, leur procédé d'obtention et leurs applications.
DE4318375A1 (de) * 1993-05-28 1994-12-01 Rottendorf Pharma Gmbh Mischung zur Schaffung von Filmüberzügen für Tabletten od. dgl.
FR2723536A1 (fr) * 1994-08-11 1996-02-16 Seth Pawan Composition permettant une liberation selective d'un principe actif

Also Published As

Publication number Publication date
AU713722B2 (en) 1999-12-09
US5840332A (en) 1998-11-24
NZ324808A (en) 1999-10-28
CZ219898A3 (cs) 1998-12-16
EP0877604B1 (en) 2005-03-23
MY133883A (en) 2007-11-30
JP2000503316A (ja) 2000-03-21
DE69732830T2 (de) 2006-04-13
DE69732830D1 (de) 2005-04-28
EP0877604A1 (en) 1998-11-18
AU1206597A (en) 1997-08-11
ZA97405B (en) 1997-07-30
ATE291417T1 (de) 2005-04-15
CZ295932B6 (cs) 2005-12-14
ES2241031T3 (es) 2005-10-16
YU1497A (sh) 1999-09-27
CN1208343A (zh) 1999-02-17
IL125042A (en) 2005-03-20
JP4165905B2 (ja) 2008-10-15
WO1997025979A1 (en) 1997-07-24
IL125042A0 (en) 1999-01-26

Similar Documents

Publication Publication Date Title
AR005451A1 (es) Dispositivo de suministro de droga por via oral para la liberación de droga localizada en el tracto gastrointestinal y uso de dicho dispositivo
PT1021171E (pt) Sistema de administracao de farmacos no tracto gastrointestinal de libertacao total prolongada
IL146708A0 (en) Delayed total release two pulse gastrointestinal drug delivery system
ES2041174T3 (es) Sistema intravenoso para suministrar un agente beneficioso.
ES2031491T3 (es) Tableta para uso farmaceutico capaz de liberar sustancias activas en momentos sucesivos.
ATE74752T1 (de) Biologisch erodierbares system mit gesteuerter freisetzung des arzneiwirkstoffes.
ES2007100A6 (es) Procedimiento para la obtencion de un sistema terapeutico oral a base de carbamazepina.
ES2138584T3 (es) Sistema de suministro de farmacos que implica la reaccion entre una proteina o un polipeptido y un polimero biodegradable hidrofobo.
ATE270880T1 (de) Im magen verweilende mikrosphären mit gesteuerter freisetzung zur verbesserten arzneistoffabgabe
MX9300998A (es) Sistema mejorado de liberacion farmaceutica y metodo para su preparacion.
EA200000267A1 (ru) Устройство доставки для длительного высвобождения лекарственных препаратов
ES2035277T3 (es) Dispositivo para poner en contacto materiales, tales como medicamentos, con un fluido.
MX9203556A (es) Una forma de dosificacion para administrar los farmacos beneficos pseudoefedrina y bromofeniramina.
ES2022454B3 (es) Sistema terapeutico para la liberacion controlada de drogas.
IL108705A0 (en) Pharmaceutical compositions containing bisacodyl in dosage form
CA2243863A1 (en) Gastrointestinal drug delivery system
DE3688355D1 (de) Fester koerper mit ueberzogenem kern.
Kaufmann et al. Adjuvant chemotherapy with chlorambucil and 5-fluorouracil in primary breast cancer (Cooperative Study Heidelberg)
Silvestrini et al. Neuroactive drugs in endocrine diseases: notes on their physiopathological and therapeutical aspects
ITGE20120007A1 (it) Dispositivo per l'introduzione di solidi in un flusso di liquido e carica preconfezionata atta a cooperare con tale dispositivo

Legal Events

Date Code Title Description
FG Grant, registration