ES2031491T3 - Tableta para uso farmaceutico capaz de liberar sustancias activas en momentos sucesivos. - Google Patents
Tableta para uso farmaceutico capaz de liberar sustancias activas en momentos sucesivos.Info
- Publication number
- ES2031491T3 ES2031491T3 ES198787119166T ES87119166T ES2031491T3 ES 2031491 T3 ES2031491 T3 ES 2031491T3 ES 198787119166 T ES198787119166 T ES 198787119166T ES 87119166 T ES87119166 T ES 87119166T ES 2031491 T3 ES2031491 T3 ES 2031491T3
- Authority
- ES
- Spain
- Prior art keywords
- active substance
- tablet
- layer
- encapsulated
- active substances
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000013543 active substance Substances 0.000 title abstract 5
- 230000004888 barrier function Effects 0.000 abstract 2
- 238000004090 dissolution Methods 0.000 abstract 2
- 239000000463 material Substances 0.000 abstract 2
- 230000015556 catabolic process Effects 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 238000005063 solubilization Methods 0.000 abstract 1
- 230000007928 solubilization Effects 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
Abstract
LA INVENCION SE REFIERE A UNA TABLETA PARA EMPLEO FARMACEUTICO CAPAZ DE LIBERAR SUSTANCIA ACTIVA EN VECES SUCESIVAS, QUE COMPRENDE POR LO MENOS UNA PRIMERA CAPA QUE CONTIENE UNA PARTE DE LA SUSTANCIA ACTIVA CON EXCIPIENTES ADECUADOS, UNA CAPA BARRERA DE MATERIAL POLIMERICO GELIFICABLE O SOLUBLE EN AGUA O EN LIQUIDOS ACUOSOS, INTERPUESTA ENTRE LA PRIMERA CAPA Y LA TERCERA CAPA QUE CONTIENE LA PARTE RESTANTE DE LA SUSTANCIA ACTIVA CON EXCIPIENTES ADECUADOS, ESTANDO LA CAPA BARRERA Y LA TERCERA CAPA ENCAPSULADAS EN UN MATERIAL POLIMERICO IMPERMEABLE E INSOLUBLE EN AGUA O SOLUBLE EN MEDIO ALCALINO. LA PARTE DE SUSTANCIA ACTIVA NO ENCAPSULADA SE LIBERA INMEDIATAMENTE POR DISOLUCION, MIENTRAS QUE LA PARTE ENCAPSULADA SE LIBERA SOLO DESPUES DE LA DISOLUCION O ROTURA DE LA CAPA BARRERA O DESPUES DE LA SOLUBILIZACION DE LA SUSTANCIA ENCAPSULANTE.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT19064/87A IT1201136B (it) | 1987-01-13 | 1987-01-13 | Compressa per uso farmaceutico atta al rilascio in tempi successivi di sostanze attive |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2031491T3 true ES2031491T3 (es) | 1992-12-16 |
Family
ID=11154233
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES198787119166T Expired - Lifetime ES2031491T3 (es) | 1987-01-13 | 1987-12-23 | Tableta para uso farmaceutico capaz de liberar sustancias activas en momentos sucesivos. |
Country Status (10)
Country | Link |
---|---|
US (1) | US4865849A (es) |
EP (1) | EP0274734B1 (es) |
JP (1) | JPS63190822A (es) |
KR (1) | KR880008805A (es) |
AT (1) | ATE64528T1 (es) |
AU (1) | AU610112B2 (es) |
DE (1) | DE3770937D1 (es) |
ES (1) | ES2031491T3 (es) |
IT (1) | IT1201136B (es) |
NZ (1) | NZ223160A (es) |
Families Citing this family (66)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5190760A (en) * | 1989-07-08 | 1993-03-02 | Coopers Animal Health Limited | Solid pharmaceutical composition |
GB8915716D0 (en) * | 1989-07-08 | 1989-08-31 | Coopers Animal Health | Pharmaceutical compositions |
SE464275B (sv) * | 1989-07-31 | 1991-04-08 | Aagerup Bengt | Ny anvaendning av beta-receptorblockerare foer beredning av ett preparat verksamt mot menieres sjukdom |
IT1237904B (it) * | 1989-12-14 | 1993-06-18 | Ubaldo Conte | Compresse a rilascio a velocita' controllata delle sostanze attive |
IE66933B1 (en) * | 1990-01-15 | 1996-02-07 | Elan Corp Plc | Controlled absorption naproxen formulation for once-daily administration |
US5198227A (en) * | 1990-01-22 | 1993-03-30 | Mcneil-Ppc, Inc. | Dual subcoated simulated capsule medicament |
US5213807A (en) * | 1990-05-03 | 1993-05-25 | Chemburkar Pramod B | Pharmaceutical composition containing ibuprofen and a prostaglandin |
US5133892A (en) * | 1990-10-17 | 1992-07-28 | Lever Brothers Company, Division Of Conopco, Inc. | Machine dishwashing detergent tablets |
US5387421A (en) * | 1991-01-31 | 1995-02-07 | Tsrl, Inc. | Multi stage drug delivery system |
US5976571A (en) * | 1991-01-31 | 1999-11-02 | Port Systems, L.L.C. | Method for making a multi-stage drug delivery system |
US5674530A (en) * | 1991-01-31 | 1997-10-07 | Port Systems, L.L.C. | Method for making a multi-stage drug delivery system |
EP0521388B1 (de) * | 1991-07-01 | 1995-05-10 | Gerhard Dr. Gergely | Verfahren zur Herstellung einer pharmazeutischen Zubereitung mit wenigstens zwei verschiedenen Wirkstoffen und Verwendung einer solchen Zubereitung |
US5256440A (en) * | 1992-06-22 | 1993-10-26 | Merck & Co., Inc. | Process for producing a tablet core aperture |
US5609884A (en) * | 1992-08-31 | 1997-03-11 | G. D. Searle & Co. | Controlled release naproxen sodium plus naproxen combination tablet |
WO1994023705A1 (en) * | 1993-04-20 | 1994-10-27 | Tsrl, Inc. | Multi-stage drug delivery system |
IT1264517B1 (it) * | 1993-05-31 | 1996-09-24 | Ekita Investments Nv | Compressa farmaceutica atta al rilascio in tempi successivi dei principi attivi in essa veicolati |
US6183778B1 (en) | 1993-09-21 | 2001-02-06 | Jagotec Ag | Pharmaceutical tablet capable of liberating one or more drugs at different release rates |
GB9401894D0 (en) | 1994-02-01 | 1994-03-30 | Rhone Poulenc Rorer Ltd | New compositions of matter |
AU746091B2 (en) * | 1995-04-03 | 2002-04-18 | Chugai Seiyaku Kabushiki Kaisha | Sucralfate containing pharmaceutical composition |
CA2217233A1 (en) * | 1995-04-03 | 1996-10-10 | Chugai Seiyaku Kabushiki Kaisha | Sucralfate containing pharmaceutical composition |
US5783212A (en) * | 1996-02-02 | 1998-07-21 | Temple University--of the Commonwealth System of Higher Education | Controlled release drug delivery system |
IT1282576B1 (it) * | 1996-02-06 | 1998-03-31 | Jagotec Ag | Compressa farmaceutica atta a cedere la sostanza attiva in tempi successivi e predeterminabili |
BE1011045A3 (fr) * | 1997-03-14 | 1999-04-06 | Ucb Sa | Compositions pharmaceutiques pour la liberation controlee de substances actives. |
RU2236847C2 (ru) | 1998-11-02 | 2004-09-27 | Илан Корпорейшн, Плк. | Композиции в виде множества частиц с модифицированным высвобождением |
SA99191255B1 (ar) | 1998-11-30 | 2006-11-25 | جي دي سيرل اند كو | مركبات سيليكوكسيب celecoxib |
US6555139B2 (en) | 1999-06-28 | 2003-04-29 | Wockhardt Europe Limited | Preparation of micron-size pharmaceutical particles by microfluidization |
US6245913B1 (en) | 1999-06-30 | 2001-06-12 | Wockhardt Europe Limited | Synthetic procedure for 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio]-IH-benzimidazole hydrochloride and its conversion to omeprazole |
US10179130B2 (en) | 1999-10-29 | 2019-01-15 | Purdue Pharma L.P. | Controlled release hydrocodone formulations |
IL149352A0 (en) | 1999-10-29 | 2002-11-10 | Euro Celtique Sa | Controlled release hydrocodone formulations |
AR030557A1 (es) * | 2000-04-14 | 2003-08-27 | Jagotec Ag | Una tableta en multicapa de liberacion controlada y metodo de tratamiento |
JP2004512354A (ja) | 2000-10-30 | 2004-04-22 | ユーロ−セルティーク,エス.エイ. | ヒドロコドン放出制御製剤 |
US20040137062A1 (en) * | 2001-05-25 | 2004-07-15 | Sham Chopra | Chronotherapy tablet and methods related thereto |
US7838026B2 (en) | 2001-09-28 | 2010-11-23 | Mcneil-Ppc, Inc. | Burst-release polymer composition and dosage forms comprising the same |
US7122143B2 (en) | 2001-09-28 | 2006-10-17 | Mcneil-Ppc, Inc. | Methods for manufacturing dosage forms |
ATE404179T1 (de) | 2001-09-28 | 2008-08-15 | Mcneil Ppc Inc | Darreichungsformen mit kern und äusserer hülle |
US20030104052A1 (en) * | 2001-10-25 | 2003-06-05 | Bret Berner | Gastric retentive oral dosage form with restricted drug release in the lower gastrointestinal tract |
CA2409552A1 (en) | 2001-10-25 | 2003-04-25 | Depomed, Inc. | Gastric retentive oral dosage form with restricted drug release in the lower gastrointestinal tract |
US20030152622A1 (en) * | 2001-10-25 | 2003-08-14 | Jenny Louie-Helm | Formulation of an erodible, gastric retentive oral diuretic |
US20030091630A1 (en) * | 2001-10-25 | 2003-05-15 | Jenny Louie-Helm | Formulation of an erodible, gastric retentive oral dosage form using in vitro disintegration test data |
ITMI20020514A1 (it) * | 2002-03-12 | 2003-09-12 | Jagotec Ag | Sistema terapeutico per il rilascio controllato di uno o piu' principi attivi |
DE10297745T5 (de) * | 2002-06-04 | 2006-03-02 | J.B. Chemicals & Pharmaceuticals Ltd. | Pharmazeutische Zusammensetzung für ein System zur kontrollierten Arzneistoffabgabe |
WO2003101431A1 (en) * | 2002-06-04 | 2003-12-11 | J.B. Chemicals & Pharmaceuticals Ltd. | Pharmaceutical composition for controlled drug delivery system |
DE10248652A1 (de) * | 2002-10-18 | 2004-04-29 | Solvay Interox Gmbh | Verfahren zur Herstellung von staubfreien Erdalkaliperoxiden |
WO2006009602A2 (en) | 2004-06-16 | 2006-01-26 | Tap Pharmaceutical Products, Inc. | Multiple ppi dosage form |
PL1791530T3 (pl) | 2004-08-23 | 2009-01-30 | Pejo Iserlohn Heilmittel Und Diaet Gmbh & Co Kg | Kompozycja farmaceutyczna zawierająca psychostymulant |
EP1830791B1 (en) * | 2004-11-19 | 2014-09-10 | GlaxoSmithKline LLC | Pharmaceutical product |
US20060233882A1 (en) * | 2005-04-15 | 2006-10-19 | Sowden Harry S | Osmotic dosage form |
US8673352B2 (en) | 2005-04-15 | 2014-03-18 | Mcneil-Ppc, Inc. | Modified release dosage form |
US20090069275A1 (en) * | 2006-02-17 | 2009-03-12 | Rocca Jose G | Low flush niacin formulation |
EA015304B1 (ru) | 2006-08-03 | 2011-06-30 | Нитек Фарма Аг | Лечение ревматоидного заболевания глюкокортикоидами с отсроченным высвобождением |
US8128460B2 (en) * | 2006-09-14 | 2012-03-06 | The Material Works, Ltd. | Method of producing rust inhibitive sheet metal through scale removal with a slurry blasting descaling cell |
EP2101713A1 (en) * | 2006-12-05 | 2009-09-23 | Universita' Degli Studi Di Parma | New modules, new assemblage kits and new assemblies for the controlled release of substances |
CA2923102C (en) | 2007-08-13 | 2019-10-15 | Abuse Deterrent Pharmaceutical Llc | Abuse resistant drugs, method of use and method of making |
CN104069088A (zh) | 2007-10-12 | 2014-10-01 | 武田制药北美公司 | 与食物摄入无关的治疗胃肠病症的方法 |
US20100233259A1 (en) * | 2008-12-12 | 2010-09-16 | Pascal Grenier | Dosage form of ropinirole |
WO2010084188A1 (en) * | 2009-01-26 | 2010-07-29 | Nitec Pharma Ag | Delayed-release glucocorticoid treatment of asthma |
EP2405901A1 (en) | 2009-03-09 | 2012-01-18 | Council of Scientific & Industrial Research | Pulsatile release composition of therapeutic agent |
CN102639122A (zh) * | 2009-12-07 | 2012-08-15 | 麦克内尔-Ppc股份有限公司 | 调释剂型的部分浸渍包衣 |
DK3326611T3 (da) | 2012-02-22 | 2020-08-17 | Duchesnay Inc | Formulering af doxylamin og pyridoxin og / eller metaboliter eller salt deraf |
GB201303781D0 (en) | 2013-03-04 | 2013-04-17 | Gauthier Pierre Pascal | Oral timer device and method of using same |
EP2976082A4 (en) | 2013-03-15 | 2016-05-11 | Inspirion Delivery Technologies Llc | MISS-INFANT COMPOSITIONS AND METHODS OF USE |
NZ716017A (en) | 2013-07-22 | 2020-07-31 | Duchesnay Inc | Composition for the management of nausea and vomiting |
KR101890649B1 (ko) * | 2013-07-30 | 2018-09-28 | 라이온 가부시키가이샤 | 정제 |
US10729685B2 (en) | 2014-09-15 | 2020-08-04 | Ohemo Life Sciences Inc. | Orally administrable compositions and methods of deterring abuse by intranasal administration |
KR101965283B1 (ko) * | 2016-05-05 | 2019-04-03 | 트리아스텍 인코포레이티드 | 제어 방출 제형 |
CN116406260A (zh) * | 2020-11-30 | 2023-07-07 | Ss制药株式会社 | 含有布洛芬的固体制剂 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL109293C (es) * | 1955-12-22 | |||
FR2100858B1 (es) * | 1970-07-03 | 1975-06-06 | Daiichi Seiyaku Co | |
JPS5333885Y2 (es) * | 1974-08-01 | 1978-08-21 | ||
US4139589A (en) * | 1975-02-26 | 1979-02-13 | Monique Beringer | Process for the manufacture of a multi-zone tablet and tablet manufactured by this process |
HU174057B (hu) * | 1976-09-17 | 1979-10-28 | Richter Gedeon Vegyeszet | Sostav dlja pokrytij obespechivajuhhij uregulirovannuju otdachy aktivnogo vehhestva biologicheski aktivnykh preparatov i sposob poluchenija takikh preparatov s uregulirovannoj otdachej aktivnogo vehhestva |
DE3221425A1 (de) * | 1982-06-07 | 1983-12-08 | Boehringer Ingelheim KG, 6507 Ingelheim | Hydrolyseempfindlichen wirkstoff enthaltende, lagerstabile tablette |
IT1188212B (it) * | 1985-12-20 | 1988-01-07 | Paolo Colombo | Sistema per il rilascio a velocita' controllata di sostanze attive |
US4756911A (en) * | 1986-04-16 | 1988-07-12 | E. R. Squibb & Sons, Inc. | Controlled release formulation |
US4753790A (en) * | 1986-12-16 | 1988-06-28 | Warner-Lambert Company | Sorbitol coated comestible and method of preparation |
US4786911A (en) * | 1987-11-10 | 1988-11-22 | The Boeing Company | Apparatus for circularly polarized radiation from surface wave transmission line |
-
1987
- 1987-01-13 IT IT19064/87A patent/IT1201136B/it active
- 1987-12-23 DE DE8787119166T patent/DE3770937D1/de not_active Expired - Fee Related
- 1987-12-23 ES ES198787119166T patent/ES2031491T3/es not_active Expired - Lifetime
- 1987-12-23 EP EP19870119166 patent/EP0274734B1/en not_active Expired - Lifetime
- 1987-12-23 AT AT87119166T patent/ATE64528T1/de not_active IP Right Cessation
- 1987-12-30 US US07/139,635 patent/US4865849A/en not_active Expired - Fee Related
-
1988
- 1988-01-11 AU AU10179/88A patent/AU610112B2/en not_active Ceased
- 1988-01-12 NZ NZ223160A patent/NZ223160A/xx unknown
- 1988-01-13 JP JP63003917A patent/JPS63190822A/ja active Pending
- 1988-01-13 KR KR1019880000165A patent/KR880008805A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
IT8719064A0 (it) | 1987-01-13 |
EP0274734B1 (en) | 1991-06-19 |
KR880008805A (ko) | 1988-09-13 |
DE3770937D1 (de) | 1991-07-25 |
AU1017988A (en) | 1988-07-14 |
EP0274734A1 (en) | 1988-07-20 |
ATE64528T1 (de) | 1991-07-15 |
NZ223160A (en) | 1990-09-26 |
JPS63190822A (ja) | 1988-08-08 |
IT1201136B (it) | 1989-01-27 |
AU610112B2 (en) | 1991-05-16 |
US4865849A (en) | 1989-09-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2031491T3 (es) | Tableta para uso farmaceutico capaz de liberar sustancias activas en momentos sucesivos. | |
DE68907139D1 (de) | Mikrokapsel mit verzoegerter freigabe fuer wasserloesliche arzneistoffe. | |
ES2044206T3 (es) | Procedimiento para la obtencion de un sistema terapeutico transdermal en forma de un emplasto con varias capas. | |
DE3363321D1 (en) | Long-lasting three layered pharmaceutical film preparations | |
ES2037082T3 (es) | Una composicion para la liberacion controlada de un farmaco. | |
HUP9904174A2 (hu) | Bőrön át történő adagoláshoz szánt gyógyszerkészítmények | |
ES2023649B3 (es) | Formas de dosificacion y administracion para medicamentos, reactivos o similares asi como procedimiento para su obtencion. | |
ES2010648A4 (es) | Formulaciones farmaceuticas de sustancias labiles frente a los acidospara uso oral. | |
ATE65023T1 (de) | Pharmazeutische mittel. | |
IE871584L (en) | Sustained release capsule. | |
ES2189018T3 (es) | Utilizacion de polvos de polimeros o granulados de polimeros redispersables para el revestimiento de formas de administracion farmaceuticas o agroquimicas. | |
ES2166769T3 (es) | Comprimido farmaceutico de liberacion controlada que presenta forma lenticular. | |
SE9704401D0 (sv) | Matrix pellets for greasy, oily or sticky drug substances | |
ATE103819T1 (de) | Pharmazeutische praeparate. | |
SE8701479D0 (sv) | Metod for inneslutning av biologiskt verksamma preparat samt anvendning derav | |
SE9704400D0 (sv) | Porous inorganic particles as carriers for drug substances | |
SE8803935L (sv) | Laekemedelskomposition | |
DE69710121D1 (de) | Pharmazeutische Zusammensetzung aus stabilisierten lipophilen Matrizen mit kontrollierter Wirkstofffreisetzung | |
AR012996A1 (es) | Uso de un sensibilizador a la insulina para la preparacion de un medicamento y composicion farmaceutica que comprende dicho sensibilizador. | |
DE60001717D1 (de) | Mikrokapseln mit verzögerter freisetzung von wirkstoffen | |
DE69529079D1 (de) | Codein enthaltende formulierungen | |
DE3772954D1 (de) | Arzneimittel mit verzoegerter wirkstoffabgabe. | |
ATE300293T1 (de) | Pharmazeutische zusammensetzungen, die schwerlösliche arzneistoffe enthalten | |
ATE90555T1 (de) | Scleroglucan und wirkstoff enthaltende pharmazeutische tabletten und kapselgranulate. | |
ES2137966T3 (es) | Vehiculos para administracion oral de substancias farmaceuticamente activas inestables frente a los acidos. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
Ref document number: 274734 Country of ref document: ES |