ES2031491T3 - Tableta para uso farmaceutico capaz de liberar sustancias activas en momentos sucesivos. - Google Patents

Tableta para uso farmaceutico capaz de liberar sustancias activas en momentos sucesivos.

Info

Publication number
ES2031491T3
ES2031491T3 ES198787119166T ES87119166T ES2031491T3 ES 2031491 T3 ES2031491 T3 ES 2031491T3 ES 198787119166 T ES198787119166 T ES 198787119166T ES 87119166 T ES87119166 T ES 87119166T ES 2031491 T3 ES2031491 T3 ES 2031491T3
Authority
ES
Spain
Prior art keywords
active substance
tablet
layer
encapsulated
active substances
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198787119166T
Other languages
English (en)
Inventor
Aldo La Manna
Paolo Colombo
Ubaldo Conte
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PHARMAIDEA Srl
Original Assignee
PHARMAIDEA Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PHARMAIDEA Srl filed Critical PHARMAIDEA Srl
Application granted granted Critical
Publication of ES2031491T3 publication Critical patent/ES2031491T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer

Abstract

LA INVENCION SE REFIERE A UNA TABLETA PARA EMPLEO FARMACEUTICO CAPAZ DE LIBERAR SUSTANCIA ACTIVA EN VECES SUCESIVAS, QUE COMPRENDE POR LO MENOS UNA PRIMERA CAPA QUE CONTIENE UNA PARTE DE LA SUSTANCIA ACTIVA CON EXCIPIENTES ADECUADOS, UNA CAPA BARRERA DE MATERIAL POLIMERICO GELIFICABLE O SOLUBLE EN AGUA O EN LIQUIDOS ACUOSOS, INTERPUESTA ENTRE LA PRIMERA CAPA Y LA TERCERA CAPA QUE CONTIENE LA PARTE RESTANTE DE LA SUSTANCIA ACTIVA CON EXCIPIENTES ADECUADOS, ESTANDO LA CAPA BARRERA Y LA TERCERA CAPA ENCAPSULADAS EN UN MATERIAL POLIMERICO IMPERMEABLE E INSOLUBLE EN AGUA O SOLUBLE EN MEDIO ALCALINO. LA PARTE DE SUSTANCIA ACTIVA NO ENCAPSULADA SE LIBERA INMEDIATAMENTE POR DISOLUCION, MIENTRAS QUE LA PARTE ENCAPSULADA SE LIBERA SOLO DESPUES DE LA DISOLUCION O ROTURA DE LA CAPA BARRERA O DESPUES DE LA SOLUBILIZACION DE LA SUSTANCIA ENCAPSULANTE.
ES198787119166T 1987-01-13 1987-12-23 Tableta para uso farmaceutico capaz de liberar sustancias activas en momentos sucesivos. Expired - Lifetime ES2031491T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT19064/87A IT1201136B (it) 1987-01-13 1987-01-13 Compressa per uso farmaceutico atta al rilascio in tempi successivi di sostanze attive

Publications (1)

Publication Number Publication Date
ES2031491T3 true ES2031491T3 (es) 1992-12-16

Family

ID=11154233

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198787119166T Expired - Lifetime ES2031491T3 (es) 1987-01-13 1987-12-23 Tableta para uso farmaceutico capaz de liberar sustancias activas en momentos sucesivos.

Country Status (10)

Country Link
US (1) US4865849A (es)
EP (1) EP0274734B1 (es)
JP (1) JPS63190822A (es)
KR (1) KR880008805A (es)
AT (1) ATE64528T1 (es)
AU (1) AU610112B2 (es)
DE (1) DE3770937D1 (es)
ES (1) ES2031491T3 (es)
IT (1) IT1201136B (es)
NZ (1) NZ223160A (es)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5190760A (en) * 1989-07-08 1993-03-02 Coopers Animal Health Limited Solid pharmaceutical composition
GB8915716D0 (en) * 1989-07-08 1989-08-31 Coopers Animal Health Pharmaceutical compositions
SE464275B (sv) * 1989-07-31 1991-04-08 Aagerup Bengt Ny anvaendning av beta-receptorblockerare foer beredning av ett preparat verksamt mot menieres sjukdom
IT1237904B (it) * 1989-12-14 1993-06-18 Ubaldo Conte Compresse a rilascio a velocita' controllata delle sostanze attive
IE66933B1 (en) * 1990-01-15 1996-02-07 Elan Corp Plc Controlled absorption naproxen formulation for once-daily administration
US5198227A (en) * 1990-01-22 1993-03-30 Mcneil-Ppc, Inc. Dual subcoated simulated capsule medicament
US5213807A (en) * 1990-05-03 1993-05-25 Chemburkar Pramod B Pharmaceutical composition containing ibuprofen and a prostaglandin
US5133892A (en) * 1990-10-17 1992-07-28 Lever Brothers Company, Division Of Conopco, Inc. Machine dishwashing detergent tablets
US5387421A (en) * 1991-01-31 1995-02-07 Tsrl, Inc. Multi stage drug delivery system
US5976571A (en) * 1991-01-31 1999-11-02 Port Systems, L.L.C. Method for making a multi-stage drug delivery system
US5674530A (en) * 1991-01-31 1997-10-07 Port Systems, L.L.C. Method for making a multi-stage drug delivery system
EP0521388B1 (de) * 1991-07-01 1995-05-10 Gerhard Dr. Gergely Verfahren zur Herstellung einer pharmazeutischen Zubereitung mit wenigstens zwei verschiedenen Wirkstoffen und Verwendung einer solchen Zubereitung
US5256440A (en) * 1992-06-22 1993-10-26 Merck & Co., Inc. Process for producing a tablet core aperture
US5609884A (en) * 1992-08-31 1997-03-11 G. D. Searle & Co. Controlled release naproxen sodium plus naproxen combination tablet
WO1994023705A1 (en) * 1993-04-20 1994-10-27 Tsrl, Inc. Multi-stage drug delivery system
IT1264517B1 (it) * 1993-05-31 1996-09-24 Ekita Investments Nv Compressa farmaceutica atta al rilascio in tempi successivi dei principi attivi in essa veicolati
US6183778B1 (en) 1993-09-21 2001-02-06 Jagotec Ag Pharmaceutical tablet capable of liberating one or more drugs at different release rates
GB9401894D0 (en) 1994-02-01 1994-03-30 Rhone Poulenc Rorer Ltd New compositions of matter
AU746091B2 (en) * 1995-04-03 2002-04-18 Chugai Seiyaku Kabushiki Kaisha Sucralfate containing pharmaceutical composition
CA2217233A1 (en) * 1995-04-03 1996-10-10 Chugai Seiyaku Kabushiki Kaisha Sucralfate containing pharmaceutical composition
US5783212A (en) * 1996-02-02 1998-07-21 Temple University--of the Commonwealth System of Higher Education Controlled release drug delivery system
IT1282576B1 (it) * 1996-02-06 1998-03-31 Jagotec Ag Compressa farmaceutica atta a cedere la sostanza attiva in tempi successivi e predeterminabili
BE1011045A3 (fr) * 1997-03-14 1999-04-06 Ucb Sa Compositions pharmaceutiques pour la liberation controlee de substances actives.
RU2236847C2 (ru) 1998-11-02 2004-09-27 Илан Корпорейшн, Плк. Композиции в виде множества частиц с модифицированным высвобождением
SA99191255B1 (ar) 1998-11-30 2006-11-25 جي دي سيرل اند كو مركبات سيليكوكسيب celecoxib
US6555139B2 (en) 1999-06-28 2003-04-29 Wockhardt Europe Limited Preparation of micron-size pharmaceutical particles by microfluidization
US6245913B1 (en) 1999-06-30 2001-06-12 Wockhardt Europe Limited Synthetic procedure for 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio]-IH-benzimidazole hydrochloride and its conversion to omeprazole
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
IL149352A0 (en) 1999-10-29 2002-11-10 Euro Celtique Sa Controlled release hydrocodone formulations
AR030557A1 (es) * 2000-04-14 2003-08-27 Jagotec Ag Una tableta en multicapa de liberacion controlada y metodo de tratamiento
JP2004512354A (ja) 2000-10-30 2004-04-22 ユーロ−セルティーク,エス.エイ. ヒドロコドン放出制御製剤
US20040137062A1 (en) * 2001-05-25 2004-07-15 Sham Chopra Chronotherapy tablet and methods related thereto
US7838026B2 (en) 2001-09-28 2010-11-23 Mcneil-Ppc, Inc. Burst-release polymer composition and dosage forms comprising the same
US7122143B2 (en) 2001-09-28 2006-10-17 Mcneil-Ppc, Inc. Methods for manufacturing dosage forms
ATE404179T1 (de) 2001-09-28 2008-08-15 Mcneil Ppc Inc Darreichungsformen mit kern und äusserer hülle
US20030104052A1 (en) * 2001-10-25 2003-06-05 Bret Berner Gastric retentive oral dosage form with restricted drug release in the lower gastrointestinal tract
CA2409552A1 (en) 2001-10-25 2003-04-25 Depomed, Inc. Gastric retentive oral dosage form with restricted drug release in the lower gastrointestinal tract
US20030152622A1 (en) * 2001-10-25 2003-08-14 Jenny Louie-Helm Formulation of an erodible, gastric retentive oral diuretic
US20030091630A1 (en) * 2001-10-25 2003-05-15 Jenny Louie-Helm Formulation of an erodible, gastric retentive oral dosage form using in vitro disintegration test data
ITMI20020514A1 (it) * 2002-03-12 2003-09-12 Jagotec Ag Sistema terapeutico per il rilascio controllato di uno o piu' principi attivi
DE10297745T5 (de) * 2002-06-04 2006-03-02 J.B. Chemicals & Pharmaceuticals Ltd. Pharmazeutische Zusammensetzung für ein System zur kontrollierten Arzneistoffabgabe
WO2003101431A1 (en) * 2002-06-04 2003-12-11 J.B. Chemicals & Pharmaceuticals Ltd. Pharmaceutical composition for controlled drug delivery system
DE10248652A1 (de) * 2002-10-18 2004-04-29 Solvay Interox Gmbh Verfahren zur Herstellung von staubfreien Erdalkaliperoxiden
WO2006009602A2 (en) 2004-06-16 2006-01-26 Tap Pharmaceutical Products, Inc. Multiple ppi dosage form
PL1791530T3 (pl) 2004-08-23 2009-01-30 Pejo Iserlohn Heilmittel Und Diaet Gmbh & Co Kg Kompozycja farmaceutyczna zawierająca psychostymulant
EP1830791B1 (en) * 2004-11-19 2014-09-10 GlaxoSmithKline LLC Pharmaceutical product
US20060233882A1 (en) * 2005-04-15 2006-10-19 Sowden Harry S Osmotic dosage form
US8673352B2 (en) 2005-04-15 2014-03-18 Mcneil-Ppc, Inc. Modified release dosage form
US20090069275A1 (en) * 2006-02-17 2009-03-12 Rocca Jose G Low flush niacin formulation
EA015304B1 (ru) 2006-08-03 2011-06-30 Нитек Фарма Аг Лечение ревматоидного заболевания глюкокортикоидами с отсроченным высвобождением
US8128460B2 (en) * 2006-09-14 2012-03-06 The Material Works, Ltd. Method of producing rust inhibitive sheet metal through scale removal with a slurry blasting descaling cell
EP2101713A1 (en) * 2006-12-05 2009-09-23 Universita' Degli Studi Di Parma New modules, new assemblage kits and new assemblies for the controlled release of substances
CA2923102C (en) 2007-08-13 2019-10-15 Abuse Deterrent Pharmaceutical Llc Abuse resistant drugs, method of use and method of making
CN104069088A (zh) 2007-10-12 2014-10-01 武田制药北美公司 与食物摄入无关的治疗胃肠病症的方法
US20100233259A1 (en) * 2008-12-12 2010-09-16 Pascal Grenier Dosage form of ropinirole
WO2010084188A1 (en) * 2009-01-26 2010-07-29 Nitec Pharma Ag Delayed-release glucocorticoid treatment of asthma
EP2405901A1 (en) 2009-03-09 2012-01-18 Council of Scientific & Industrial Research Pulsatile release composition of therapeutic agent
CN102639122A (zh) * 2009-12-07 2012-08-15 麦克内尔-Ppc股份有限公司 调释剂型的部分浸渍包衣
DK3326611T3 (da) 2012-02-22 2020-08-17 Duchesnay Inc Formulering af doxylamin og pyridoxin og / eller metaboliter eller salt deraf
GB201303781D0 (en) 2013-03-04 2013-04-17 Gauthier Pierre Pascal Oral timer device and method of using same
EP2976082A4 (en) 2013-03-15 2016-05-11 Inspirion Delivery Technologies Llc MISS-INFANT COMPOSITIONS AND METHODS OF USE
NZ716017A (en) 2013-07-22 2020-07-31 Duchesnay Inc Composition for the management of nausea and vomiting
KR101890649B1 (ko) * 2013-07-30 2018-09-28 라이온 가부시키가이샤 정제
US10729685B2 (en) 2014-09-15 2020-08-04 Ohemo Life Sciences Inc. Orally administrable compositions and methods of deterring abuse by intranasal administration
KR101965283B1 (ko) * 2016-05-05 2019-04-03 트리아스텍 인코포레이티드 제어 방출 제형
CN116406260A (zh) * 2020-11-30 2023-07-07 Ss制药株式会社 含有布洛芬的固体制剂

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL109293C (es) * 1955-12-22
FR2100858B1 (es) * 1970-07-03 1975-06-06 Daiichi Seiyaku Co
JPS5333885Y2 (es) * 1974-08-01 1978-08-21
US4139589A (en) * 1975-02-26 1979-02-13 Monique Beringer Process for the manufacture of a multi-zone tablet and tablet manufactured by this process
HU174057B (hu) * 1976-09-17 1979-10-28 Richter Gedeon Vegyeszet Sostav dlja pokrytij obespechivajuhhij uregulirovannuju otdachy aktivnogo vehhestva biologicheski aktivnykh preparatov i sposob poluchenija takikh preparatov s uregulirovannoj otdachej aktivnogo vehhestva
DE3221425A1 (de) * 1982-06-07 1983-12-08 Boehringer Ingelheim KG, 6507 Ingelheim Hydrolyseempfindlichen wirkstoff enthaltende, lagerstabile tablette
IT1188212B (it) * 1985-12-20 1988-01-07 Paolo Colombo Sistema per il rilascio a velocita' controllata di sostanze attive
US4756911A (en) * 1986-04-16 1988-07-12 E. R. Squibb & Sons, Inc. Controlled release formulation
US4753790A (en) * 1986-12-16 1988-06-28 Warner-Lambert Company Sorbitol coated comestible and method of preparation
US4786911A (en) * 1987-11-10 1988-11-22 The Boeing Company Apparatus for circularly polarized radiation from surface wave transmission line

Also Published As

Publication number Publication date
IT8719064A0 (it) 1987-01-13
EP0274734B1 (en) 1991-06-19
KR880008805A (ko) 1988-09-13
DE3770937D1 (de) 1991-07-25
AU1017988A (en) 1988-07-14
EP0274734A1 (en) 1988-07-20
ATE64528T1 (de) 1991-07-15
NZ223160A (en) 1990-09-26
JPS63190822A (ja) 1988-08-08
IT1201136B (it) 1989-01-27
AU610112B2 (en) 1991-05-16
US4865849A (en) 1989-09-12

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