DE69529079D1 - Codein enthaltende formulierungen - Google Patents

Codein enthaltende formulierungen

Info

Publication number
DE69529079D1
DE69529079D1 DE69529079T DE69529079T DE69529079D1 DE 69529079 D1 DE69529079 D1 DE 69529079D1 DE 69529079 T DE69529079 T DE 69529079T DE 69529079 T DE69529079 T DE 69529079T DE 69529079 D1 DE69529079 D1 DE 69529079D1
Authority
DE
Germany
Prior art keywords
weight
codeine
codein
formulations containing
extraction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69529079T
Other languages
English (en)
Other versions
DE69529079T2 (de
Inventor
Shing Yue Chan
David Charles James
Peter Owen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Publication of DE69529079D1 publication Critical patent/DE69529079D1/de
Application granted granted Critical
Publication of DE69529079T2 publication Critical patent/DE69529079T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A61K47/585—Ion exchange resins, e.g. polystyrene sulfonic acid resin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
DE69529079T 1994-09-14 1995-09-14 Codein enthaltende formulierungen Expired - Lifetime DE69529079T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPM8149A AUPM814994A0 (en) 1994-09-14 1994-09-14 Codeine-containing formulations
PCT/AU1995/000601 WO1996008252A1 (en) 1994-09-14 1995-09-14 Codeine containing formulations

Publications (2)

Publication Number Publication Date
DE69529079D1 true DE69529079D1 (de) 2003-01-16
DE69529079T2 DE69529079T2 (de) 2003-11-13

Family

ID=3782668

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69529079T Expired - Lifetime DE69529079T2 (de) 1994-09-14 1995-09-14 Codein enthaltende formulierungen

Country Status (11)

Country Link
EP (1) EP0781135B1 (de)
CN (1) CN1095666C (de)
AT (1) ATE228842T1 (de)
AU (1) AUPM814994A0 (de)
CZ (1) CZ286736B6 (de)
DE (1) DE69529079T2 (de)
ES (1) ES2188670T3 (de)
HU (1) HUT77386A (de)
NZ (1) NZ292847A (de)
PL (1) PL181260B1 (de)
WO (1) WO1996008252A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9708559A (pt) * 1996-04-10 1999-08-03 Warner Lambert Co Desnaturantes para sais de amina simpatomimetica
DE19740983A1 (de) 1997-09-18 1999-04-08 Warner Lambert Co N D Ges D St Verfahren zur Erschwerung der Extraktion von Wirkstoffen aus Tabletten
WO1999032119A1 (en) * 1997-12-22 1999-07-01 Euro-Celtique, S.A. Opioid agonist/antagonist combinations
GT199900148A (es) 1998-09-10 2001-02-28 Desnaturalizantes para las sales aminas simpaticomimeticas.
CN100450548C (zh) * 2006-12-22 2009-01-14 江苏奥赛康药业有限公司 一种波拉克林树脂组合物的口腔贴片及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2530563C2 (de) * 1975-07-09 1986-07-24 Bayer Ag, 5090 Leverkusen Analgetische Arzneimittel mit vermindertem Mißbrauchspotential
US4443428A (en) * 1982-06-21 1984-04-17 Euroceltique, S.A. Extended action controlled release compositions
GB8629567D0 (en) * 1986-12-10 1987-01-21 Boots Co Plc Therapeutic agents
US4971785A (en) * 1988-03-14 1990-11-20 Spectrum Consumer Products Co., Inc. Non-alcoholic delivery system for orally ingestible active ingredients
NZ234587A (en) * 1989-08-04 1991-11-26 Mcneil Ppc Inc A chewable pharmaceutical tablet of compressed coated granules
DD295988A5 (de) * 1990-06-26 1991-11-21 Chemie Ag Bitterfeld-Wolfen,De Codeinpraeparat und verfahren zu seiner herstellung

Also Published As

Publication number Publication date
WO1996008252A1 (en) 1996-03-21
CN1160349A (zh) 1997-09-24
PL319160A1 (en) 1997-07-21
ES2188670T3 (es) 2003-07-01
HUT77386A (hu) 1998-04-28
DE69529079T2 (de) 2003-11-13
NZ292847A (en) 1998-11-25
AUPM814994A0 (en) 1994-10-06
CN1095666C (zh) 2002-12-11
EP0781135A1 (de) 1997-07-02
CZ77397A3 (en) 1997-08-13
ATE228842T1 (de) 2002-12-15
CZ286736B6 (en) 2000-06-14
PL181260B1 (pl) 2001-06-29
EP0781135A4 (de) 1997-12-10
EP0781135B1 (de) 2002-12-04

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition