IT1264517B1 - Compressa farmaceutica atta al rilascio in tempi successivi dei principi attivi in essa veicolati - Google Patents
Compressa farmaceutica atta al rilascio in tempi successivi dei principi attivi in essa veicolatiInfo
- Publication number
- IT1264517B1 IT1264517B1 IT93MI001120A ITMI931120A IT1264517B1 IT 1264517 B1 IT1264517 B1 IT 1264517B1 IT 93MI001120 A IT93MI001120 A IT 93MI001120A IT MI931120 A ITMI931120 A IT MI931120A IT 1264517 B1 IT1264517 B1 IT 1264517B1
- Authority
- IT
- Italy
- Prior art keywords
- release
- pharmaceutical tablet
- active substance
- layer
- active principles
- Prior art date
Links
- 239000013543 active substance Substances 0.000 abstract 3
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000004888 barrier function Effects 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Compressa farmaceutica atta al rilascio in tempi successivi dei principi attivi in essa veicolati preparata mediante: a) preparazione di una compressa costituita da 3 strati sovrapposti dei quali lo strato superiore comprende una sostanza attiva, lo strato intermedio non contiene sostanza attiva e costituisce uno strato barriera e lo strato inferiore comprende una sostanza attiva, detto strato superiore presentando una porzione rilevata sulla faccia superiore, b) rivestimento completo della compressa con un film polimerico impermeabile e c) asportazione di detta porzione rilevata portando così a contatto con l'ambiente la corrispondente superficie della composizione di detto strato superiore.
Priority Applications (14)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT93MI001120A IT1264517B1 (it) | 1993-05-31 | 1993-05-31 | Compressa farmaceutica atta al rilascio in tempi successivi dei principi attivi in essa veicolati |
AT94107834T ATE183386T1 (de) | 1993-05-31 | 1994-05-20 | Pharmazeutische tablette geeignet zur gestuften freisetzung von wirkstoffen |
DK94107834T DK0631775T3 (da) | 1993-05-31 | 1994-05-20 | Farmaceutisk tablet, som trinvist kan frigive de aktive bestanddele |
EP94107834A EP0631775B1 (en) | 1993-05-31 | 1994-05-20 | Pharmaceutical tablet capable of releasing the active ingredients at subsequent times |
SI9430288T SI0631775T1 (en) | 1993-05-31 | 1994-05-20 | Pharmaceutical tablet capable of releasing the active ingredients at subsequent times |
DE69420087T DE69420087T2 (de) | 1993-05-31 | 1994-05-20 | Pharmazeutische Tablette geeignet zur gestuften Freisetzung von Wirkstoffen |
ES94107834T ES2138633T3 (es) | 1993-05-31 | 1994-05-20 | Tableta farmaceutica capaz de liberar los ingredientes activos en tiempos sucesivos. |
US08/248,338 US5487901A (en) | 1993-05-31 | 1994-05-24 | Process for preparing pharmaceutical tablet capable of releasing the active ingredients contained therein at subsequent times |
CA002124553A CA2124553C (en) | 1993-05-31 | 1994-05-27 | Pharmaceutical tablet capable of releasing the active ingredients contained therein at subsequent times |
AU63426/94A AU677833B2 (en) | 1993-05-31 | 1994-05-30 | Pharmaceutical tablet capable of releasing the active ingredients contained therein at subsequent times |
JP6139659A JPH07138150A (ja) | 1993-05-31 | 1994-05-31 | 中に含まれた活性成分を連続の時間で放出できる医薬錠剤 |
NZ260630A NZ260630A (en) | 1993-05-31 | 1994-05-31 | Tri-layer sustained release tablet coated with impermeable film apart from a small area on one face |
US08/547,246 US5650169A (en) | 1993-05-31 | 1995-10-24 | Pharmaceutical tablet capable of releasing the active ingredients contained therein at subsequent times |
GR990402933T GR3031841T3 (en) | 1993-05-31 | 1999-11-15 | Pharmaceutical tablet capable of releasing the active ingredients at subsequent times. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT93MI001120A IT1264517B1 (it) | 1993-05-31 | 1993-05-31 | Compressa farmaceutica atta al rilascio in tempi successivi dei principi attivi in essa veicolati |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI931120A0 ITMI931120A0 (it) | 1993-05-31 |
ITMI931120A1 ITMI931120A1 (it) | 1994-12-01 |
IT1264517B1 true IT1264517B1 (it) | 1996-09-24 |
Family
ID=11366293
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT93MI001120A IT1264517B1 (it) | 1993-05-31 | 1993-05-31 | Compressa farmaceutica atta al rilascio in tempi successivi dei principi attivi in essa veicolati |
Country Status (13)
Country | Link |
---|---|
US (2) | US5487901A (it) |
EP (1) | EP0631775B1 (it) |
JP (1) | JPH07138150A (it) |
AT (1) | ATE183386T1 (it) |
AU (1) | AU677833B2 (it) |
CA (1) | CA2124553C (it) |
DE (1) | DE69420087T2 (it) |
DK (1) | DK0631775T3 (it) |
ES (1) | ES2138633T3 (it) |
GR (1) | GR3031841T3 (it) |
IT (1) | IT1264517B1 (it) |
NZ (1) | NZ260630A (it) |
SI (1) | SI0631775T1 (it) |
Families Citing this family (84)
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FI93924C (fi) * | 1991-09-17 | 1995-06-26 | Martti Lauri Antero Marvola | Menetelmä säädellysti lääkeainetta vapauttavan valmisteen valmistamiseksi |
US6183778B1 (en) | 1993-09-21 | 2001-02-06 | Jagotec Ag | Pharmaceutical tablet capable of liberating one or more drugs at different release rates |
GB9407386D0 (en) | 1994-04-14 | 1994-06-08 | Smithkline Beecham Plc | Pharmaceutical formulation |
US5534263A (en) | 1995-02-24 | 1996-07-09 | Alza Corporation | Active agent dosage form comprising a matrix and at least two insoluble bands |
HUP9802086A3 (en) * | 1995-02-28 | 2001-02-28 | Aventis Pharmaceuticals Inc Br | Pharmaceutical composition for piperidinoalkanol compounds |
US20030109503A1 (en) * | 1995-06-06 | 2003-06-12 | Smithkline Beecham P.L.C. | Pharmaceutical formulations comprising clavulanic acid alone or in combination with other beta-lactam antibiotics |
IT1282576B1 (it) * | 1996-02-06 | 1998-03-31 | Jagotec Ag | Compressa farmaceutica atta a cedere la sostanza attiva in tempi successivi e predeterminabili |
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US5843477A (en) * | 1997-09-30 | 1998-12-01 | Bayer Corporation | Lubricants for use in tabletting |
US6465009B1 (en) | 1998-03-18 | 2002-10-15 | Yamanouchi Pharmaceutical Co., Ltd. | Water soluble polymer-based rapidly dissolving tablets and production processes thereof |
US20030153607A1 (en) * | 1998-11-12 | 2003-08-14 | Smithkline Beecham P.L.C. | Novel composition and use |
US20090060995A1 (en) * | 2005-01-13 | 2009-03-05 | Kamalinder Kaur Singh | Dispersible sustained release pharmaceutical compositions |
US7250176B1 (en) * | 1999-04-13 | 2007-07-31 | Beecham Pharmaceuticals (Pte) Limited | Method of treating a bacterial infection |
US6878386B1 (en) | 1999-04-13 | 2005-04-12 | Beecham Pharmaceuticals (Pte) Limited | Method of treating a bacterial infection comprising amoxycillin and potassium clavulanate |
US6294199B1 (en) * | 1999-04-13 | 2001-09-25 | Beecham Pharmaceuticals (Pte) Limited | Method of treating a bacterial infection comprising administering amoxycillin |
US6555139B2 (en) | 1999-06-28 | 2003-04-29 | Wockhardt Europe Limited | Preparation of micron-size pharmaceutical particles by microfluidization |
EP1064937A1 (en) * | 1999-06-28 | 2001-01-03 | Sanofi-Synthelabo | Timed dual release dosage forms comprising a short acting hypnotic or a salt thereof |
US6245913B1 (en) | 1999-06-30 | 2001-06-12 | Wockhardt Europe Limited | Synthetic procedure for 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio]-IH-benzimidazole hydrochloride and its conversion to omeprazole |
AU2277101A (en) * | 1999-12-20 | 2001-07-03 | Schering Corporation | Stable extended release oral dosage composition |
AU2276801A (en) * | 1999-12-20 | 2001-07-03 | Schering Corporation | Extended release oral dosage composition |
AR030557A1 (es) | 2000-04-14 | 2003-08-27 | Jagotec Ag | Una tableta en multicapa de liberacion controlada y metodo de tratamiento |
US6372252B1 (en) | 2000-04-28 | 2002-04-16 | Adams Laboratories, Inc. | Guaifenesin sustained release formulation and tablets |
US8012504B2 (en) * | 2000-04-28 | 2011-09-06 | Reckitt Benckiser Inc. | Sustained release of guaifenesin combination drugs |
US7985420B2 (en) * | 2000-04-28 | 2011-07-26 | Reckitt Benckiser Inc. | Sustained release of guaifenesin combination drugs |
US6955821B2 (en) | 2000-04-28 | 2005-10-18 | Adams Laboratories, Inc. | Sustained release formulations of guaifenesin and additional drug ingredients |
US7838032B2 (en) * | 2000-04-28 | 2010-11-23 | Reckitt Benckiser Inc. | Sustained release of guaifenesin |
US6756057B2 (en) | 2000-10-12 | 2004-06-29 | Beecham Pharmaceuticals (Pte) Limited | Amoxicillin and potassium clavulanate dosage form |
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US20030070584A1 (en) | 2001-05-15 | 2003-04-17 | Cynthia Gulian | Dip coating compositions containing cellulose ethers |
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US20030152622A1 (en) * | 2001-10-25 | 2003-08-14 | Jenny Louie-Helm | Formulation of an erodible, gastric retentive oral diuretic |
GB0203296D0 (en) | 2002-02-12 | 2002-03-27 | Glaxo Group Ltd | Novel composition |
ITMI20020515A1 (it) * | 2002-03-12 | 2003-09-12 | Jagotec Ag | Sistema per il rilasco controllato di uno o piu' principi attivi |
ITMI20020514A1 (it) * | 2002-03-12 | 2003-09-12 | Jagotec Ag | Sistema terapeutico per il rilascio controllato di uno o piu' principi attivi |
US20060013875A1 (en) * | 2002-05-29 | 2006-01-19 | Impax Laboratories, Inc. | Combination immediate release controlled release levodopa/carbidopa dosage forms |
US8637512B2 (en) | 2002-07-29 | 2014-01-28 | Glaxo Group Limited | Formulations and method of treatment |
US7429619B2 (en) | 2002-08-02 | 2008-09-30 | Mcneil Consumer Healthcare | Polyacrylic film forming compositions |
US20040115265A1 (en) * | 2002-12-11 | 2004-06-17 | Loutfy Benkerrour | Multilayered tablet containing pravastatin and aspirin and method |
TW200517127A (en) * | 2003-08-07 | 2005-06-01 | Sb Pharmco Inc | Novel composition |
US10213387B2 (en) | 2003-09-19 | 2019-02-26 | Sun Pharma Advanced Research Company Ltd. | Oral drug delivery system |
US10226428B2 (en) | 2003-09-19 | 2019-03-12 | Sun Pharma Advanced Research Company Ltd. | Oral drug delivery system |
AU2004283565C1 (en) * | 2003-09-19 | 2011-10-27 | Sun Pharma Advanced Research Company Limited | Oral drug delivery system |
FR2861299B1 (fr) | 2003-10-28 | 2006-01-27 | Pf Medicament | Compositions pharmaceutiques a base de derives d'idasoxan sous formes polymorphes |
US7595335B2 (en) * | 2003-10-28 | 2009-09-29 | Pierre Fabre Medicament | Pharmaceutical composition based on idazoxan, salts, hydrates or polymorphs thereof |
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US20050202079A1 (en) * | 2004-03-15 | 2005-09-15 | Mylan Pharmaceuticals Inc. | Novel orally administrable formulation of nitrofurantoin and a method for preparing said formulation |
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JP4681843B2 (ja) * | 2004-09-30 | 2011-05-11 | 日本臓器製薬株式会社 | 固形医薬製剤 |
US20090264495A1 (en) * | 2005-02-17 | 2009-10-22 | Standard Chem. & Pharm. Co., Ltd. | Oral sustained-release pharmaceutical composition of indapamide, production and use thereof |
US20060182803A1 (en) * | 2005-02-17 | 2006-08-17 | Standard Chem. & Pharm. Co., Ltd. | Oral sustained-release pharmaceutical composition of indapamide, production and use thereof |
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US20100233259A1 (en) * | 2008-12-12 | 2010-09-16 | Pascal Grenier | Dosage form of ropinirole |
US10485770B2 (en) | 2009-12-21 | 2019-11-26 | Aptapharma, Inc. | Functionally-coated multilayer tablets |
CN102665807A (zh) | 2010-01-05 | 2012-09-12 | 微剂量治疗技术公司 | 吸入设备和方法 |
BR112012030708A2 (pt) * | 2010-06-01 | 2016-11-01 | Grünenthal S A | composições farmacêuticas do ibuprofeno e um antagonista do receptor h2 |
EP2726062A1 (en) | 2011-06-29 | 2014-05-07 | Ranbaxy Laboratories Limited | Multilayered dosage form |
GB201303781D0 (en) | 2013-03-04 | 2013-04-17 | Gauthier Pierre Pascal | Oral timer device and method of using same |
CN105658211A (zh) | 2013-10-07 | 2016-06-08 | 怡百克制药公司 | 左旋多巴和/或左旋多巴的酯的粘膜粘附性、控制释放调配物和其用途 |
US10987313B2 (en) | 2013-10-07 | 2021-04-27 | Impax Laboratories, Llc | Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof |
WO2016192680A1 (en) | 2015-06-03 | 2016-12-08 | Triastek, Inc. | Dosage forms and use thereof |
US11278506B2 (en) | 2015-10-09 | 2022-03-22 | Rb Health (Us) Llc | Pharmaceutical formulation |
RU2602681C1 (ru) * | 2015-11-09 | 2016-11-20 | Федеральное государственное бюджетное образовательное учреждение высшего образования Первый Московский государственный медицинский университет имени И.М. Сеченова Министерства здравоохранения Российской Федерации (ФГБОУ ВО Первый МГМУ им. И.М. Сеченова Минздрава России) | Способ получения капсул диклофенака |
EP3551173A1 (en) | 2016-12-09 | 2019-10-16 | Bayer Animal Health GmbH | Pharmaceutical preparation and method for its manufacture |
EP3573602A4 (en) * | 2017-01-26 | 2020-09-16 | Triastek, Inc. | DOSAGE FORMS OF CONTROLLED RELEASE AT SPECIFIC GASTROINTESTINAL SITES |
USD907235S1 (en) * | 2017-09-18 | 2021-01-05 | University Of Hertfordshire Higher Education Corporation | Enclosure for dissolution system |
WO2019137200A1 (en) | 2018-01-09 | 2019-07-18 | Triastek, Inc. | Oral drug dosage forms comprising a fixed-dose of an adhd non-stimulant and an adhd stimulant |
WO2020255837A1 (ja) * | 2019-06-17 | 2020-12-24 | 東和薬品株式会社 | 時限式溶出マスキング粒子およびそれを含有する経口医薬組成物 |
US11986449B2 (en) | 2020-12-22 | 2024-05-21 | Amneal Pharmaceuticals Llc | Levodopa dosing regimen |
CN115624125B (zh) * | 2022-10-28 | 2024-03-08 | 广州王老吉大健康产业有限公司 | 一种泡腾片及其制备方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2100858B1 (it) * | 1970-07-03 | 1975-06-06 | Daiichi Seiyaku Co | |
EP0230654B1 (en) * | 1985-12-28 | 1992-03-18 | Sumitomo Pharmaceuticals Company, Limited | Sustained pulsewise release pharmaceutical preparation |
IT1201136B (it) * | 1987-01-13 | 1989-01-27 | Resa Farma | Compressa per uso farmaceutico atta al rilascio in tempi successivi di sostanze attive |
-
1993
- 1993-05-31 IT IT93MI001120A patent/IT1264517B1/it active IP Right Grant
-
1994
- 1994-05-20 DE DE69420087T patent/DE69420087T2/de not_active Expired - Lifetime
- 1994-05-20 AT AT94107834T patent/ATE183386T1/de active
- 1994-05-20 ES ES94107834T patent/ES2138633T3/es not_active Expired - Lifetime
- 1994-05-20 EP EP94107834A patent/EP0631775B1/en not_active Expired - Lifetime
- 1994-05-20 SI SI9430288T patent/SI0631775T1/xx unknown
- 1994-05-20 DK DK94107834T patent/DK0631775T3/da active
- 1994-05-24 US US08/248,338 patent/US5487901A/en not_active Expired - Lifetime
- 1994-05-27 CA CA002124553A patent/CA2124553C/en not_active Expired - Lifetime
- 1994-05-30 AU AU63426/94A patent/AU677833B2/en not_active Expired
- 1994-05-31 NZ NZ260630A patent/NZ260630A/xx not_active IP Right Cessation
- 1994-05-31 JP JP6139659A patent/JPH07138150A/ja active Pending
-
1995
- 1995-10-24 US US08/547,246 patent/US5650169A/en not_active Expired - Lifetime
-
1999
- 1999-11-15 GR GR990402933T patent/GR3031841T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
ITMI931120A1 (it) | 1994-12-01 |
US5487901A (en) | 1996-01-30 |
GR3031841T3 (en) | 2000-02-29 |
EP0631775A1 (en) | 1995-01-04 |
DE69420087D1 (de) | 1999-09-23 |
ITMI931120A0 (it) | 1993-05-31 |
SI0631775T1 (en) | 2000-02-29 |
DK0631775T3 (da) | 2000-03-06 |
JPH07138150A (ja) | 1995-05-30 |
ATE183386T1 (de) | 1999-09-15 |
US5650169A (en) | 1997-07-22 |
DE69420087T2 (de) | 2000-03-23 |
AU677833B2 (en) | 1997-05-08 |
CA2124553A1 (en) | 1994-12-01 |
AU6342694A (en) | 1994-12-08 |
NZ260630A (en) | 1995-08-28 |
CA2124553C (en) | 2000-04-18 |
EP0631775B1 (en) | 1999-08-18 |
ES2138633T3 (es) | 2000-01-16 |
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