ES2170245T3 - Metodo para la fabricacion de comprimidos estratificados para la liberacion controlada de principios activos. - Google Patents

Metodo para la fabricacion de comprimidos estratificados para la liberacion controlada de principios activos.

Info

Publication number
ES2170245T3
ES2170245T3 ES96922890T ES96922890T ES2170245T3 ES 2170245 T3 ES2170245 T3 ES 2170245T3 ES 96922890 T ES96922890 T ES 96922890T ES 96922890 T ES96922890 T ES 96922890T ES 2170245 T3 ES2170245 T3 ES 2170245T3
Authority
ES
Spain
Prior art keywords
matrix
layers
contact surfaces
controlled release
prefabricated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96922890T
Other languages
English (en)
Inventor
Karsten Cremer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LTS Lohmann Therapie Systeme AG
Original Assignee
LTS Lohmann Therapie Systeme AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LTS Lohmann Therapie Systeme AG filed Critical LTS Lohmann Therapie Systeme AG
Application granted granted Critical
Publication of ES2170245T3 publication Critical patent/ES2170245T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Financial Or Insurance-Related Operations Such As Payment And Settlement (AREA)
  • Electrotherapy Devices (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

LA INVENCION TRATA DE UNA TABLETA RECUBIERTA PARA LA LIBERACION CONTROLADA DE SUSTANCIAS ACTIVAS EN UN MEDIO LIQUIDO CON AL MENOS UNA MATRIZ EN CAPAS, QUE CONTIENE SUSTANCIAS ACTIVAS Y QUE MUESTRA UNAS SUPERFICIES DE CONTACTO PARA CONTACTAR CON EL MEDIO LIQUIDO. LAS SUPERFICIES DE CONTACTO DE LA MATRIZ CONTIENEN, EN PARTE, UNA CAPA DE RECUBRIMIENTO QUE RETARDA O IMPIDE LA LIBERACION DE LAS SUSTANCIAS ACTIVAS. LA INVENCION ESTA CARACTERIZADA PORQUE LA CAPA DE RECUBRIMIENTO ES UNA CAPA ADICIONAL APLICADA A LAS SUPERFICIES DE CONTACTO DE LA MATRIZ PREFABRICADA EN CAPAS O LA MATRIZ ES AL MENOS UNA CAPA ADICIONAL QUE CONTACTA CON LAS SUPERFICIES DE CONTACTO DE LA MATRIZ PREFABRICADA EN CAPAS; LA CAPA ADICIONAL SE APLICA PRENSANDO MATERIAL GRANULADO O PULVERULENTO SOBRE LA MATRIZ PREFABRICADA EN CAPAS CON UN ESPESOR EN GRADIENTE O LA CAPA DE RECUBRIMIENTO PREFABRICADA EN CAPAS.
ES96922890T 1995-07-07 1996-06-24 Metodo para la fabricacion de comprimidos estratificados para la liberacion controlada de principios activos. Expired - Lifetime ES2170245T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19524753A DE19524753A1 (de) 1995-07-07 1995-07-07 Schichttablette zur kontrollierten Freisetzung von Wirkstoffen

Publications (1)

Publication Number Publication Date
ES2170245T3 true ES2170245T3 (es) 2002-08-01

Family

ID=7766243

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96922890T Expired - Lifetime ES2170245T3 (es) 1995-07-07 1996-06-24 Metodo para la fabricacion de comprimidos estratificados para la liberacion controlada de principios activos.

Country Status (20)

Country Link
US (1) US6083533A (es)
EP (1) EP0837674B1 (es)
JP (1) JPH11510484A (es)
KR (1) KR100404121B1 (es)
CN (1) CN1190343A (es)
AT (1) ATE210972T1 (es)
AU (1) AU710828B2 (es)
CZ (1) CZ420997A3 (es)
DE (2) DE19524753A1 (es)
DK (1) DK0837674T3 (es)
ES (1) ES2170245T3 (es)
HU (1) HUP9901715A3 (es)
MY (1) MY113919A (es)
NO (1) NO976140D0 (es)
NZ (1) NZ312136A (es)
PL (1) PL324487A1 (es)
PT (1) PT837674E (es)
SK (1) SK1498A3 (es)
WO (1) WO1997002812A2 (es)
ZA (1) ZA965710B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6555139B2 (en) 1999-06-28 2003-04-29 Wockhardt Europe Limited Preparation of micron-size pharmaceutical particles by microfluidization
HRP20020124A2 (en) * 2002-02-11 2003-10-31 Pliva D D Sustained/controlled release solid formulation as a novel drug delivery system with reduced risk of dose dumping
US7309444B2 (en) * 2002-08-29 2007-12-18 Stellar Technology Company Layered tablet water treatment compositions and method of use
US6852238B2 (en) * 2002-08-29 2005-02-08 Steller Technology Company Layered tablet water treatment compositions and method of use
US20060251722A1 (en) * 2005-05-03 2006-11-09 Novavax, Inc. Multi-component vitamin and mineral supplement for the optimal absorption of components
US20080286343A1 (en) * 2007-05-16 2008-11-20 Dzenana Cengic Solid form
US9328325B2 (en) 2008-12-31 2016-05-03 3M Innovative Properties Company Sampling devices and methods for concentrating microorganisms
CN102325596B (zh) 2008-12-31 2015-04-29 3M创新有限公司 使用微粒进行的活生物负载检测
WO2010129726A1 (en) * 2009-05-06 2010-11-11 3M Innovative Properties Company Articles with matrix comprising a cell extractant and biodetection methods thereof
JP5972174B2 (ja) 2009-12-30 2016-08-17 スリーエム イノベイティブ プロパティズ カンパニー 微小粒子を用いた生きた生物負荷の検出法
US8845801B2 (en) 2009-12-30 2014-09-30 Regents Of The University Of Minnesota Bone cement and method
CN110538158A (zh) * 2019-09-10 2019-12-06 郑州百瑞动物药业有限公司 一种水产用长效缓释双层片状消毒剂及其制备方法
CN113768038A (zh) * 2021-09-14 2021-12-10 江苏省协同医药生物工程有限责任公司 一种精准定量实验动物功能性饲料及制备方法与设备

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1248571A (en) * 1917-04-30 1917-12-04 Francis J Stokes Machine for applying and compressing powder on tablets.
DE3221425A1 (de) * 1982-06-07 1983-12-08 Boehringer Ingelheim KG, 6507 Ingelheim Hydrolyseempfindlichen wirkstoff enthaltende, lagerstabile tablette
DE3814532A1 (de) * 1988-04-29 1989-11-09 Bayer Ag Dhp-retard-zubereitung
DE4100920A1 (de) * 1991-01-15 1992-07-16 Degussa Wirkstoffzubereitung zur oralen verabreichung an wiederkaeuer
IT1256393B (it) * 1992-11-17 1995-12-04 Inverni Della Beffa Spa Forme matriciali multistrato per il rilascio controllato di principi attivi
DE4341442C2 (de) * 1993-12-04 1998-11-05 Lohmann Therapie Syst Lts Vorrichtung zur kontrollierten Freisetzung von Wirkstoffen sowie ihre Verwendung
DE4416926C2 (de) * 1994-05-13 2000-01-13 Lohmann Therapie Syst Lts Verfahren zur Herstellung von Vorrichtungen zur kontrollierten Freisetzung von Wirkstoffen

Also Published As

Publication number Publication date
WO1997002812A3 (de) 1997-03-27
KR100404121B1 (ko) 2004-02-11
PT837674E (pt) 2002-06-28
WO1997002812A2 (de) 1997-01-30
US6083533A (en) 2000-07-04
MX9800244A (es) 1998-07-31
DE59608511D1 (de) 2002-01-31
HUP9901715A2 (hu) 1999-10-28
EP0837674A2 (de) 1998-04-29
CN1190343A (zh) 1998-08-12
NZ312136A (en) 1999-02-25
KR19990028783A (ko) 1999-04-15
NO976140L (no) 1997-12-30
AU6359896A (en) 1997-02-10
EP0837674B1 (de) 2001-12-19
MY113919A (en) 2002-06-29
SK1498A3 (en) 1998-09-09
DE19524753A1 (de) 1997-01-23
ATE210972T1 (de) 2002-01-15
NO976140D0 (no) 1997-12-30
PL324487A1 (en) 1998-05-25
JPH11510484A (ja) 1999-09-14
AU710828B2 (en) 1999-09-30
DK0837674T3 (da) 2002-04-08
ZA965710B (en) 1997-01-24
HUP9901715A3 (en) 2001-04-28
CZ420997A3 (cs) 1998-06-17

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