BR112012030708A2 - composições farmacêuticas do ibuprofeno e um antagonista do receptor h2 - Google Patents

composições farmacêuticas do ibuprofeno e um antagonista do receptor h2

Info

Publication number
BR112012030708A2
BR112012030708A2 BR112012030708A BR112012030708A BR112012030708A2 BR 112012030708 A2 BR112012030708 A2 BR 112012030708A2 BR 112012030708 A BR112012030708 A BR 112012030708A BR 112012030708 A BR112012030708 A BR 112012030708A BR 112012030708 A2 BR112012030708 A2 BR 112012030708A2
Authority
BR
Brazil
Prior art keywords
pharmaceutical compositions
ibuprofen
receptor antagonist
ibuprofen pharmaceutical
administering
Prior art date
Application number
BR112012030708A
Other languages
English (en)
Inventor
George Tidmarsh
Iain Duncan
Puneet Sharma
Original Assignee
Grünenthal S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Grünenthal S A filed Critical Grünenthal S A
Publication of BR112012030708A2 publication Critical patent/BR112012030708A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)

Abstract

composições farmacêuticas do ibuprofeno e um antagonista do receptor h~2 ~. composições farmacêuticas de um antagonista do receptor h2 e ibuprofeno são aqui fornecidas. as composições compreendem, por exemplo, um núcleo e uma casca separados por uma composiçõa ou formulação líquida de uma camada, duas camadas ou três camadas de barreira. também são fornecidos métodos de preparação das composições farmacêuticas e métodos de tratamento compreendendo a administração das composições farmacêuticas. também é fornecido um método para a administração de ibuprofeno a um sujeito em necessidade de tratamento de ibuprofeno, no qual uma composição farmacêutica compreendendo uma quantidade terapeuticamente eficaz de ibuprofeno e de uma quantidade terapeuticamente eficaz de um h2ra, tal como famotidina, é administrada três vezes por dia.
BR112012030708A 2010-06-01 2011-05-31 composições farmacêuticas do ibuprofeno e um antagonista do receptor h2 BR112012030708A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US35035110P 2010-06-01 2010-06-01
US35159410P 2010-06-04 2010-06-04
PCT/US2011/038622 WO2011153168A1 (en) 2010-06-01 2011-05-31 Pharmaceutical compositions of ibuprofen and an h2 receptor antagonist

Publications (1)

Publication Number Publication Date
BR112012030708A2 true BR112012030708A2 (pt) 2016-11-01

Family

ID=45067050

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012030708A BR112012030708A2 (pt) 2010-06-01 2011-05-31 composições farmacêuticas do ibuprofeno e um antagonista do receptor h2

Country Status (5)

Country Link
US (2) US20130078287A1 (pt)
BR (1) BR112012030708A2 (pt)
CO (1) CO6640251A2 (pt)
MX (1) MX338629B (pt)
WO (1) WO2011153168A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2913049B1 (en) 2014-02-27 2016-11-30 Galenicum Health S.L. Stable pharmaceutical compositions

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1264517B1 (it) * 1993-05-31 1996-09-24 Ekita Investments Nv Compressa farmaceutica atta al rilascio in tempi successivi dei principi attivi in essa veicolati
US20030035839A1 (en) * 2001-05-15 2003-02-20 Peirce Management, Llc Pharmaceutical composition for both intraoral and oral administration
US20040081695A1 (en) * 2002-09-28 2004-04-29 Sowden Harry S Dosage forms having an inner core and an outer shell
CA2554012A1 (en) * 2003-01-21 2004-08-05 Smartrix Technologies Inc. Oral dosage formulation
FR2855756B1 (fr) * 2003-06-06 2005-08-26 Ethypharm Sa Comprime orodispersible multicouche
US8067451B2 (en) * 2006-07-18 2011-11-29 Horizon Pharma Usa, Inc. Methods and medicaments for administration of ibuprofen
CA2620123C (en) * 2005-08-24 2011-11-22 The Board Of Trustees Of The Leland Stanford Junior University Methods for treating and monitoring inflammation and redox imbalance in cystic fibrosis
US8067033B2 (en) * 2007-11-30 2011-11-29 Horizon Pharma Usa, Inc. Stable compositions of famotidine and ibuprofen
MX2010011435A (es) * 2008-04-18 2011-01-25 Reata Pharmaceuticals Inc Compuestos que incluyen un nucleo farmaceutico antiinflamatorio y sus metodos de uso.
US20100112054A1 (en) * 2008-10-23 2010-05-06 Appian Labs, Llc Tablets and discs with compartments with two or more drugs for release at certain intervals and with specific rates

Also Published As

Publication number Publication date
WO2011153168A1 (en) 2011-12-08
US20130078287A1 (en) 2013-03-28
MX338629B (es) 2016-04-26
US20140322313A1 (en) 2014-10-30
CO6640251A2 (es) 2013-03-22
MX2012013970A (es) 2013-03-21

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

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