ATE350021T1 - Pharmazeutische formulierung enthaltend trägerkügelchen mit aufgebrachter schicht aus valaciclovir - Google Patents

Pharmazeutische formulierung enthaltend trägerkügelchen mit aufgebrachter schicht aus valaciclovir

Info

Publication number
ATE350021T1
ATE350021T1 AT01926063T AT01926063T ATE350021T1 AT E350021 T1 ATE350021 T1 AT E350021T1 AT 01926063 T AT01926063 T AT 01926063T AT 01926063 T AT01926063 T AT 01926063T AT E350021 T1 ATE350021 T1 AT E350021T1
Authority
AT
Austria
Prior art keywords
valaciclovir
pharmaceutical formulation
layer
carrier beads
formulation containing
Prior art date
Application number
AT01926063T
Other languages
English (en)
Inventor
Koho Kawamura
Yasuhiro Mishima
Kiyoshi Ohtsuka
Nobuya Sugibayashi
Keiichi Sugisawa
Hitomi Yanagihara
Makio Yasuda
Original Assignee
Glaxosmithkline Kabushiki Kais
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Kabushiki Kais filed Critical Glaxosmithkline Kabushiki Kais
Application granted granted Critical
Publication of ATE350021T1 publication Critical patent/ATE350021T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
AT01926063T 2000-04-28 2001-04-27 Pharmazeutische formulierung enthaltend trägerkügelchen mit aufgebrachter schicht aus valaciclovir ATE350021T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0010446.3A GB0010446D0 (en) 2000-04-28 2000-04-28 Pharmaceutical formulation

Publications (1)

Publication Number Publication Date
ATE350021T1 true ATE350021T1 (de) 2007-01-15

Family

ID=9890736

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01926063T ATE350021T1 (de) 2000-04-28 2001-04-27 Pharmazeutische formulierung enthaltend trägerkügelchen mit aufgebrachter schicht aus valaciclovir

Country Status (11)

Country Link
US (1) US20030108615A1 (de)
EP (1) EP1278515B1 (de)
JP (2) JP4141688B2 (de)
KR (1) KR100803490B1 (de)
AT (1) ATE350021T1 (de)
AU (1) AU781197B2 (de)
CA (1) CA2433897A1 (de)
DE (1) DE60125750T2 (de)
ES (1) ES2280362T3 (de)
GB (1) GB0010446D0 (de)
WO (1) WO2001082905A1 (de)

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Publication number Priority date Publication date Assignee Title
KR20040016202A (ko) * 2002-08-16 2004-02-21 주식회사 제이알팜 쓴맛이 차폐된 히드로코르티손 경구용 약제 조성물 및 그제조방법
WO2008005534A2 (en) * 2006-07-06 2008-01-10 Forest Laboratories, Inc. Orally dissolving formulations of memantine
JP5405752B2 (ja) * 2007-01-31 2014-02-05 大日本住友製薬株式会社 被覆された薬物含有粒子および該粒子を含む固形製剤
EP2165706A1 (de) 2008-09-18 2010-03-24 BioAlliance Pharma Behandlung von Entzündungsschmerzen der Mundhöhlenschleimhäute unter Verwendung von therapeutischen mukosalen, bioadhäsiven Trägern mit verlängerter Abgabe
US8592434B2 (en) 2009-12-09 2013-11-26 Bioalliance Pharma Sa Mucoadhesive buccal tablets for the treatment of orofacial herpes
CA2782779C (en) * 2009-12-09 2015-07-14 Bioalliance Pharma Mucoadhesive buccal tablets for the treatment of orofacial herpes
EP2335690A1 (de) * 2009-12-09 2011-06-22 BioAlliance Pharma Mukoadhäsive bukkale Tabletten zur Behandlung von orofazialem Herpes
US20120149720A1 (en) * 2010-07-30 2012-06-14 Ranbaxy Laboratories Limited Valacyclovir formulations
US8993041B2 (en) * 2012-10-15 2015-03-31 New Jersey Institute Of Technology Taste masked active pharmaceutical powder compositions and processes for making them
WO2014159051A1 (en) * 2013-03-13 2014-10-02 Advanced Bionutrition Corp. Stable bioactive substances and methods of making
CA3013795A1 (en) * 2016-02-17 2017-08-24 Corr-Jensen Inc. Time release vitamins and minerals in edible oils

Family Cites Families (20)

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Publication number Priority date Publication date Assignee Title
US487613A (en) 1892-12-06 Toy wagon
US4874613A (en) * 1987-03-06 1989-10-17 Baker Cummins Pharmaceuticals, Inc. Taste concealing pharmaceutical dosage unit
GB8719367D0 (en) * 1987-08-15 1987-09-23 Wellcome Found Therapeutic compounds
US4938966A (en) * 1988-11-30 1990-07-03 Riker Laboratories, Inc. Controlled release flecainide acetate formulation
DE3903217A1 (de) * 1989-02-03 1990-08-09 Boehringer Ingelheim Vetmed Verfahren zur herstellung fester pharmazeutischer zubereitungen
SK282071B6 (sk) * 1991-01-30 2001-10-08 The Wellcome Foundation Limited Tableta dispergovateľná vo vode a spôsob jej prípravy
JPH04283520A (ja) * 1991-03-12 1992-10-08 Asahi Chem Ind Co Ltd 球状核および球形顆粒
JP2665858B2 (ja) * 1992-05-30 1997-10-22 日本ヘキスト・マリオン・ルセル株式会社 持効性塩酸オキシブチニン製剤
JPH0826977A (ja) * 1994-07-19 1996-01-30 Tanabe Seiyaku Co Ltd 溶出制御型経口製剤
GB9501178D0 (en) * 1995-01-20 1995-03-08 Wellcome Found Guanine derivative
GB9501127D0 (en) * 1995-01-20 1995-03-08 Wellcome Found Tablet
JPH0971524A (ja) * 1995-09-08 1997-03-18 Fujisawa Pharmaceut Co Ltd 徐放性粒剤およびその製造方法
GB9518465D0 (en) * 1995-09-09 1995-11-08 Smithkline Beecham Seiyaku Kk Pharmaceuticals
DE69726255T2 (de) * 1996-01-19 2004-08-26 Glaxo Group Ltd., Greenford Verwendung von valaciclovir zur herstellung eines arzneimittels zur behandlung von genitalherpes durch einmal tägliche verabreichung
US6248636B1 (en) * 1998-05-28 2001-06-19 Samsung Electronics Co., Ltd. Method for forming contact holes of semiconductor memory device
JP3466921B2 (ja) * 1998-06-03 2003-11-17 大塚製薬株式会社 味マスキング医薬製剤
JP2000103732A (ja) * 1998-07-28 2000-04-11 Tanabe Seiyaku Co Ltd 腸内適所放出型製剤
JP2000053563A (ja) * 1998-08-07 2000-02-22 Bayer Yakuhin Ltd 苦味がマスクされた速放性細粒剤
KR100396171B1 (ko) * 1998-08-10 2003-08-27 아사히 가세이 가부시키가이샤 염산 파수딜의 경구 서방성 제제
US6248363B1 (en) * 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions

Also Published As

Publication number Publication date
AU781197B2 (en) 2005-05-12
KR100803490B1 (ko) 2008-02-14
AU5265801A (en) 2001-11-12
KR20030011834A (ko) 2003-02-11
DE60125750D1 (de) 2007-02-15
JP2006290903A (ja) 2006-10-26
JP4141688B2 (ja) 2008-08-27
ES2280362T3 (es) 2007-09-16
GB0010446D0 (en) 2000-06-14
JP2003531851A (ja) 2003-10-28
WO2001082905A1 (en) 2001-11-08
CA2433897A1 (en) 2001-11-08
EP1278515A1 (de) 2003-01-29
EP1278515B1 (de) 2007-01-03
DE60125750T2 (de) 2007-10-31
US20030108615A1 (en) 2003-06-12

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