ES2137966T3 - Vehiculos para administracion oral de substancias farmaceuticamente activas inestables frente a los acidos. - Google Patents
Vehiculos para administracion oral de substancias farmaceuticamente activas inestables frente a los acidos.Info
- Publication number
- ES2137966T3 ES2137966T3 ES93201612T ES93201612T ES2137966T3 ES 2137966 T3 ES2137966 T3 ES 2137966T3 ES 93201612 T ES93201612 T ES 93201612T ES 93201612 T ES93201612 T ES 93201612T ES 2137966 T3 ES2137966 T3 ES 2137966T3
- Authority
- ES
- Spain
- Prior art keywords
- vehicles
- oral administration
- pharmaceutically active
- substances against
- against acids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
Abstract
MEJORAS EN LOS VEHICULOS PARA ADMINISTRACION ORAL DE SUSTANCIAS ACIDAS DEBILES FARMACOLOGICAMENTE ACTIVAS CON TENDENCIA A LA DECOLORACION, CONTENIENDO LA SUSTANCIA ACIDA DEBIL, EN DONDE EL VEHICULO DE ADMINISTRACION CONTIENE UN NUCLEO QUE CONTIENE DICHA SUSTANCIA JUNTO CON UN COMPUESTO DE REACCION ALCALINA O UNA SAL ALCALINA DE DICHA SUSTANCIA MEZCLADA OPCIONALMENTE CON UN COMPUESTO DE REACCION ALCALINA, ADOPTANDO LA FORMA DE UN NUMERO DE PEQUEÑAS PERLAS, FORMANDO OPCIONALMENTE PEQUEÑAS TABLETAS O UNA TABLETA TAL COMO LA QUE CONTIENE UNA CUBIERTA HECHA DE UNA O MAS CAPAS DE SUBCUBIERTAS DE REACCION INERTE CONTENIENDO TABLETAS EXCIPIENTES LAS CUALES SON SOLUBLES O RAPIDAMENTE DESINTEGRABLES EN AGUA, O POLIMEROS SOLUBLES EN AGUA, COMPUESTOS EN FORMA DE LAMINAS CONTENIENDO OPCIONALMENTE UN REDUCTOR DE PH, O BIEN CONTENIENDO COMPUESTOS ALCALINOS ENTRE EL NUCLEO DE REACCION ALCALINA Y UNA CAPA DE CUBIERTA ENTERICA EXTERIOR.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB08610573A GB2189699A (en) | 1986-04-30 | 1986-04-30 | Coated acid-labile medicaments |
EP92107178A EP0502556B1 (en) | 1986-04-30 | 1987-04-16 | Use of specific core material and layers to obtain pharmaceutical formulations stable to discolouration of acid labile compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2137966T3 true ES2137966T3 (es) | 2000-01-01 |
Family
ID=26130898
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES93201612T Expired - Lifetime ES2137966T3 (es) | 1986-04-30 | 1987-04-16 | Vehiculos para administracion oral de substancias farmaceuticamente activas inestables frente a los acidos. |
Country Status (2)
Country | Link |
---|---|
ES (1) | ES2137966T3 (es) |
GR (1) | GR3032639T3 (es) |
-
1987
- 1987-04-16 ES ES93201612T patent/ES2137966T3/es not_active Expired - Lifetime
-
2000
- 2000-02-11 GR GR20000400335T patent/GR3032639T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
GR3032639T3 (en) | 2000-06-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2135443T3 (es) | Vehiculo mejorado para la administracion oral de omeprazol. | |
ES2010648T3 (es) | Formulaciones farmaceuticas de sustancias labiles frente a los acidos para uso oral. | |
ES2172239T3 (es) | Sistema osmotico de liberacion de farmacos. | |
AR065827A2 (es) | Formas de dosificacion de liberacion sostenida de sertralina, sales de sertralina, composicion farmaceutica, procedimiento y preparacion y su uso en terapia | |
MY102459A (en) | Oral sustained release pharmaceutical preparation. | |
ATA131091A (de) | Orale feste pharmazeutische dosierungsform mit programmierter wirkstofffreisetzung und verfahren zu ihrer herstellung | |
IT1245761B (it) | Formulazioni farmaceutiche contenenti glicosaminoglicani assorbibili per via orale. | |
GR1001503B (el) | Μέ?οδος δια την παρασκευή φαρμακευτικών ενώσεων αι οποίαι περιέχουν ως δραστική ουσία καρβονικά οξέα τα οποία περιέχουν ?είον κα?ώς και η χρησιμοποίησις αυτών δια την καταπολέμησιν των ρετροιών. | |
SE9402431D0 (sv) | New tablet formulation | |
ES2031491T3 (es) | Tableta para uso farmaceutico capaz de liberar sustancias activas en momentos sucesivos. | |
ES2157975T3 (es) | Soluciones farmaceuticas con solubilidad mejorada. | |
TNSN98229A1 (fr) | Formulation pharmaceutique orale a liberation prolongee | |
PE71699A1 (es) | Composicion farmaceutica de descarboetoxiloratadina sin lactosa, no higroscopica y anhidra | |
RU94045950A (ru) | Фармацевтический препарат и способ его приготовления | |
DE69133623D1 (de) | Haltende neue pharmazeutische formulierungen sowie verfahren zu deren herstellung | |
ES2125342T3 (es) | Esteres y combinaciones de un nitrato organico y de un salicilato. | |
ES2053768T3 (es) | Tabletas masticables. | |
ES2055775T3 (es) | Nueva forma de dosificacion. | |
IE65251B1 (en) | Controlled release capsules | |
HU9301672D0 (en) | Method for manufacturing solid dosing forms of medicaments with controlled releasing of active agents | |
ES2137966T3 (es) | Vehiculos para administracion oral de substancias farmaceuticamente activas inestables frente a los acidos. | |
AR003434A1 (es) | Compuesto de tiludronato, composiciones farmaceuticas que los contienen y proceso para producir dicho compuesto y procedimiento para producir lascomposiciones farmaceuticas. | |
ES531346A0 (es) | Procedimiento para producir una tableta de administracion oral de liberacion controlada, independiente del ph | |
LV11820A (lv) | Karbamazepina arstnieciska forma ar paleninatu aktivas vielas izdalisanos | |
PT742716E (pt) | Composicao farmaceutica para administracao transdermica sistemica contendo a substancia activa morfina-6-glucuronido |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
Ref document number: 565210 Country of ref document: ES |