ATE300293T1 - Pharmazeutische zusammensetzungen, die schwerlösliche arzneistoffe enthalten - Google Patents

Pharmazeutische zusammensetzungen, die schwerlösliche arzneistoffe enthalten

Info

Publication number
ATE300293T1
ATE300293T1 AT98907701T AT98907701T ATE300293T1 AT E300293 T1 ATE300293 T1 AT E300293T1 AT 98907701 T AT98907701 T AT 98907701T AT 98907701 T AT98907701 T AT 98907701T AT E300293 T1 ATE300293 T1 AT E300293T1
Authority
AT
Austria
Prior art keywords
poorly soluble
pharmaceutical compositions
compositions containing
medicinal substances
soluble medicinal
Prior art date
Application number
AT98907701T
Other languages
English (en)
Inventor
William L Rocco
Sharon M Laughlin
Nancy M Franson
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/808,761 external-priority patent/US5760056A/en
Priority claimed from US08/810,560 external-priority patent/US5776987A/en
Priority claimed from US08/813,946 external-priority patent/US5837714A/en
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Application granted granted Critical
Publication of ATE300293T1 publication Critical patent/ATE300293T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT98907701T 1997-03-03 1998-02-27 Pharmazeutische zusammensetzungen, die schwerlösliche arzneistoffe enthalten ATE300293T1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US08/808,761 US5760056A (en) 1997-03-03 1997-03-03 Pharmaceutical formulation
US08/810,560 US5776987A (en) 1997-03-03 1997-03-03 Pharmaceutical suspension formulation
US08/813,946 US5837714A (en) 1997-03-03 1997-03-03 Solid pharmaceutical dispersions
US2850498A 1998-02-24 1998-02-24
PCT/US1998/004078 WO1998038987A1 (en) 1997-03-03 1998-02-27 Pharmaceutical formulations containing poorly soluble drug substances

Publications (1)

Publication Number Publication Date
ATE300293T1 true ATE300293T1 (de) 2005-08-15

Family

ID=27487679

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98907701T ATE300293T1 (de) 1997-03-03 1998-02-27 Pharmazeutische zusammensetzungen, die schwerlösliche arzneistoffe enthalten

Country Status (10)

Country Link
EP (1) EP0996436B1 (de)
JP (2) JP4510156B2 (de)
AT (1) ATE300293T1 (de)
BR (1) BR9808136A (de)
CA (1) CA2281946C (de)
DE (1) DE69830997T2 (de)
ES (1) ES2242273T3 (de)
HR (1) HRP980105A2 (de)
NO (1) NO325726B1 (de)
WO (1) WO1998038987A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6197787B1 (en) * 1997-03-03 2001-03-06 Sanofi-Synthelabo Pharmaceutical formulations containing poorly soluble drug substances
WO2000038655A1 (en) * 1998-12-23 2000-07-06 Alza Corporation Dosage forms comprising porous particles
US6342249B1 (en) 1998-12-23 2002-01-29 Alza Corporation Controlled release liquid active agent formulation dosage forms
US6387400B1 (en) * 2000-08-29 2002-05-14 R.P. Scherer Technologies, Inc. Process for preparing pharmaceutical compositions for use with soft gelatin formulations

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3169269D1 (en) * 1981-09-25 1985-04-18 Lacer Sa 1-azaxanthone for use as therapeutic agent, processes for its production and pharmaceutical compositions
US4725427A (en) * 1984-03-13 1988-02-16 Albion International, Inc. Effervescent vitamin-mineral granule preparation
US5071643A (en) * 1986-10-17 1991-12-10 R. P. Scherer Corporation Solvent system enhancing the solubility of pharmaceuticals for encapsulation
DD293499A5 (de) * 1989-06-06 1991-09-05 Arzneimittelwerk Dresden Gmbh,De Verfahren zur herstellung cyclosporinhaltiger galenischer formulierungen
FR2665898B1 (fr) * 1990-08-20 1994-03-11 Sanofi Derives d'amido-3 pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant.
KR100237733B1 (ko) * 1991-11-04 2000-01-15 리차드 디. 슈미트 소수성 액체를 위한 수용성 전달 시스템
JP3121080B2 (ja) * 1991-12-19 2000-12-25 アール・ピー・シーラー コーポレイション カプセル封入用溶液
US5376688A (en) * 1992-12-18 1994-12-27 R. P. Scherer Corporation Enhanced solubility pharmaceutical solutions
GB9302720D0 (en) * 1993-02-11 1993-03-24 Scherer Ltd R P Products in capsule form for use in aqueous solution

Also Published As

Publication number Publication date
DE69830997D1 (de) 2005-09-01
CA2281946C (en) 2007-08-07
HRP980105A2 (en) 1999-02-28
JP4510156B2 (ja) 2010-07-21
EP0996436A4 (de) 2001-04-11
NO325726B1 (no) 2008-07-07
CA2281946A1 (en) 1998-09-11
EP0996436B1 (de) 2005-07-27
NO994249D0 (no) 1999-09-02
WO1998038987A1 (en) 1998-09-11
JP5563260B2 (ja) 2014-07-30
NO994249L (no) 1999-11-03
ES2242273T3 (es) 2005-11-01
JP2002513406A (ja) 2002-05-08
BR9808136A (pt) 2000-03-28
DE69830997T2 (de) 2006-02-09
EP0996436A1 (de) 2000-05-03
JP2009286798A (ja) 2009-12-10

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