PT1021171E - Sistema de administracao de farmacos no tracto gastrointestinal de libertacao total prolongada - Google Patents

Sistema de administracao de farmacos no tracto gastrointestinal de libertacao total prolongada

Info

Publication number
PT1021171E
PT1021171E PT98949742T PT98949742T PT1021171E PT 1021171 E PT1021171 E PT 1021171E PT 98949742 T PT98949742 T PT 98949742T PT 98949742 T PT98949742 T PT 98949742T PT 1021171 E PT1021171 E PT 1021171E
Authority
PT
Portugal
Prior art keywords
core
drug
coating
gastrointestinal tract
insoluble
Prior art date
Application number
PT98949742T
Other languages
English (en)
Inventor
E Itzhak Lerner
Moshe Flashner
Adel Penhasi
Original Assignee
Dexcel Pharma Technologies Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dexcel Pharma Technologies Ltd filed Critical Dexcel Pharma Technologies Ltd
Publication of PT1021171E publication Critical patent/PT1021171E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT98949742T 1997-10-09 1998-10-01 Sistema de administracao de farmacos no tracto gastrointestinal de libertacao total prolongada PT1021171E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94823597A 1997-10-09 1997-10-09
US16320298A 1998-09-30 1998-09-30

Publications (1)

Publication Number Publication Date
PT1021171E true PT1021171E (pt) 2003-10-31

Family

ID=26859435

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98949742T PT1021171E (pt) 1997-10-09 1998-10-01 Sistema de administracao de farmacos no tracto gastrointestinal de libertacao total prolongada

Country Status (20)

Country Link
EP (1) EP1021171B1 (pt)
JP (1) JP2001519379A (pt)
KR (1) KR20010031034A (pt)
CN (1) CN100548279C (pt)
AT (1) ATE238774T1 (pt)
AU (1) AU740757B2 (pt)
BR (1) BR9815240A (pt)
CA (1) CA2305762C (pt)
CZ (1) CZ301028B6 (pt)
DE (1) DE69814122T2 (pt)
DK (1) DK1021171T3 (pt)
ES (1) ES2198756T3 (pt)
HU (1) HUP0004945A3 (pt)
IL (1) IL135502A (pt)
NO (1) NO20001829L (pt)
NZ (1) NZ503820A (pt)
PL (1) PL203733B1 (pt)
PT (1) PT1021171E (pt)
TR (1) TR200000944T2 (pt)
WO (1) WO1999018938A1 (pt)

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US6632451B2 (en) * 1999-06-04 2003-10-14 Dexcel Pharma Technologies Ltd. Delayed total release two pulse gastrointestinal drug delivery system
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CN1285333C (zh) * 2000-06-07 2006-11-22 张昊 结肠定位释放的口服制剂及其制备方法
EP1349531A1 (en) 2001-01-12 2003-10-08 Sun Pharmaceuticals Industries Ltd. Spaced drug delivery system
PT1377276E (pt) * 2001-04-10 2011-12-30 Sun Pharma Advanced Res Co Ltd Composição de libertação temporizada por pulso
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NO20021592D0 (no) 2002-04-04 2002-04-04 Fmc Biopolymer As Polysakkaridkapsler og fremgangsmåte ved fremstilling derav
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BRPI0409652A (pt) 2003-04-24 2006-04-25 Jagotec Ag tablete, embalagem farmacêutica, método de tratamento de doenças, e, método de preparação de um tablete
TWI372066B (en) 2003-10-01 2012-09-11 Wyeth Corp Pantoprazole multiparticulate formulations
KR100645019B1 (ko) * 2004-06-03 2006-11-14 주식회사 리젠 바이오텍 비수용성 무기화합물이 포집되어 있는 고분자 비드, 이의제조방법 및 용도
EP1846042A2 (en) * 2005-01-05 2007-10-24 Board of Regents, The University of Texas System Conjugates for dual imaging and radiochemotherapy: composition, manufacturing, and applications
EP1909765A1 (en) * 2005-07-22 2008-04-16 Dow Gloval Technologies Inc. Oral drug compliance monitoring using sound detection
EP1916995B2 (en) 2005-07-29 2022-06-29 Stichting Groningen Centre for Drug Research Ph-controlled pulsatile delivery system, methods for preparation and use thereof
US8679545B2 (en) 2005-11-12 2014-03-25 The Regents Of The University Of California Topical corticosteroids for the treatment of inflammatory diseases of the gastrointestinal tract
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
US8324192B2 (en) 2005-11-12 2012-12-04 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
JP5372525B2 (ja) 2006-03-03 2013-12-18 エフ エム シー コーポレーション カプセルの製造方法および該製造方法により製造されるカプセル
JP2007284483A (ja) * 2006-04-13 2007-11-01 Daito Kasei Kogyo Kk 吸湿性顔料およびそれを含有する化粧料
JP2009537548A (ja) * 2006-05-19 2009-10-29 アダマス・ファーマシューティカルズ・インコーポレーテッド ウイルス感染症の治療のための方法および組成物
UA96457C2 (ru) 2006-08-03 2011-11-10 Нитек Фарма Аг Лечение ревматоидного артрита глюкокортикоидами с отсроченным высвобождением
WO2008044236A2 (en) * 2006-10-10 2008-04-17 Dexcel Pharma Technologies Ltd. Improved release of statins in the intestine
US8865692B2 (en) 2007-11-13 2014-10-21 Meritage Pharma, Inc Compositions for the treatment of gastrointestinal inflammation
HUE038452T2 (hu) 2007-11-13 2018-10-29 Meritage Pharma Inc Gyomor és bélrendszeri gyulladások kezelésére szolgáló kompozíciók
US20090264392A1 (en) * 2008-04-21 2009-10-22 Meritage Pharma, Inc. Treating eosinophilic esophagitis
EP2179727B1 (en) * 2008-10-27 2013-05-29 Roquette Freres Water insoluble polymer: modified starch derivative-based film coatings for colon targeting
BR112013029199B1 (pt) 2011-05-13 2022-02-08 Eb Ip Hybritabs B.V. Dispositivo de distribuição de dois fármacos
AU2014373683B2 (en) 2013-12-31 2020-05-07 Rapamycin Holdings, Llc Oral rapamycin nanoparticle preparations and use
ES2841248T3 (es) 2014-02-21 2021-07-07 Principia Biopharma Inc Sales y forma sólida de un inhibidor de BTK
EP3131546B1 (en) 2014-04-16 2022-02-16 Rapamycin Holdings, Inc. Oral rapamycin preparation for use in treating feline chronic gingivo- stomatitis (fcgs)
CA2970723C (en) 2014-12-18 2023-09-05 Principia Biopharma Inc. Treatment of pemphigus
EP3236953B1 (en) * 2014-12-24 2020-11-11 Principia Biopharma Inc. Site specific dosing of a btk inhibitor
TW201718572A (zh) 2015-06-24 2017-06-01 普林斯匹亞生物製藥公司 酪胺酸激酶抑制劑
GB201511284D0 (en) * 2015-06-26 2015-08-12 Univ Witwatersrand Jhb An oral pharmaceutical dosage form for the delivery of a peptide and/or protein
CN105434403A (zh) * 2015-12-30 2016-03-30 成都医学院 一种溴吡斯的明包衣缓释微丸及其制备方法
EP3478273A1 (en) 2016-06-29 2019-05-08 Principia Biopharma Inc. Modified release formulations of 2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile
JP6780412B2 (ja) * 2016-09-28 2020-11-04 ライオン株式会社 コーティング組成物ならびにコーティング製剤及びその製造方法
CN112544964B (zh) * 2020-12-28 2024-03-19 苏州大学 一种可服用胶囊及其制备方法与应用
CN115176879B (zh) * 2022-09-09 2022-11-18 山东新和成氨基酸有限公司 一种过瘤胃蛋氨酸的制备方法

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Also Published As

Publication number Publication date
CN100548279C (zh) 2009-10-14
HUP0004945A2 (hu) 2001-08-28
AU740757B2 (en) 2001-11-15
NO20001829D0 (no) 2000-04-07
HUP0004945A3 (en) 2005-03-29
ES2198756T3 (es) 2004-02-01
TR200000944T2 (tr) 2000-11-21
PL339861A1 (en) 2001-01-15
CZ301028B6 (cs) 2009-10-14
EP1021171B1 (en) 2003-05-02
NZ503820A (en) 2004-02-27
CZ20001256A3 (cs) 2000-10-11
PL203733B1 (pl) 2009-11-30
CA2305762C (en) 2006-09-26
WO1999018938A1 (en) 1999-04-22
BR9815240A (pt) 2001-10-30
AU9600198A (en) 1999-05-03
EP1021171A1 (en) 2000-07-26
KR20010031034A (ko) 2001-04-16
CN1274280A (zh) 2000-11-22
IL135502A0 (en) 2001-05-20
DK1021171T3 (da) 2003-08-25
DE69814122D1 (de) 2003-06-05
DE69814122T2 (de) 2004-03-18
JP2001519379A (ja) 2001-10-23
CA2305762A1 (en) 1999-04-22
IL135502A (en) 2006-07-05
ATE238774T1 (de) 2003-05-15
NO20001829L (no) 2000-06-07

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