PT1021171E - Sistema de administracao de farmacos no tracto gastrointestinal de libertacao total prolongada - Google Patents
Sistema de administracao de farmacos no tracto gastrointestinal de libertacao total prolongadaInfo
- Publication number
- PT1021171E PT1021171E PT98949742T PT98949742T PT1021171E PT 1021171 E PT1021171 E PT 1021171E PT 98949742 T PT98949742 T PT 98949742T PT 98949742 T PT98949742 T PT 98949742T PT 1021171 E PT1021171 E PT 1021171E
- Authority
- PT
- Portugal
- Prior art keywords
- core
- drug
- coating
- gastrointestinal tract
- insoluble
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US94823597A | 1997-10-09 | 1997-10-09 | |
US16320298A | 1998-09-30 | 1998-09-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1021171E true PT1021171E (pt) | 2003-10-31 |
Family
ID=26859435
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT98949742T PT1021171E (pt) | 1997-10-09 | 1998-10-01 | Sistema de administracao de farmacos no tracto gastrointestinal de libertacao total prolongada |
Country Status (20)
Country | Link |
---|---|
EP (1) | EP1021171B1 (pt) |
JP (1) | JP2001519379A (pt) |
KR (1) | KR20010031034A (pt) |
CN (1) | CN100548279C (pt) |
AT (1) | ATE238774T1 (pt) |
AU (1) | AU740757B2 (pt) |
BR (1) | BR9815240A (pt) |
CA (1) | CA2305762C (pt) |
CZ (1) | CZ301028B6 (pt) |
DE (1) | DE69814122T2 (pt) |
DK (1) | DK1021171T3 (pt) |
ES (1) | ES2198756T3 (pt) |
HU (1) | HUP0004945A3 (pt) |
IL (1) | IL135502A (pt) |
NO (1) | NO20001829L (pt) |
NZ (1) | NZ503820A (pt) |
PL (1) | PL203733B1 (pt) |
PT (1) | PT1021171E (pt) |
TR (1) | TR200000944T2 (pt) |
WO (1) | WO1999018938A1 (pt) |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5534263A (en) | 1995-02-24 | 1996-07-09 | Alza Corporation | Active agent dosage form comprising a matrix and at least two insoluble bands |
US6231888B1 (en) * | 1996-01-18 | 2001-05-15 | Perio Products Ltd. | Local delivery of non steroidal anti inflammatory drugs (NSAIDS) to the colon as a treatment for colonic polyps |
US6632451B2 (en) * | 1999-06-04 | 2003-10-14 | Dexcel Pharma Technologies Ltd. | Delayed total release two pulse gastrointestinal drug delivery system |
EP1203590B1 (en) | 1999-08-09 | 2007-07-04 | Dainippon Sumitomo Pharma Co., Ltd. | Solid preparations containing chitosan powder and process for producing the same |
CN1285333C (zh) * | 2000-06-07 | 2006-11-22 | 张昊 | 结肠定位释放的口服制剂及其制备方法 |
EP1349531A1 (en) | 2001-01-12 | 2003-10-08 | Sun Pharmaceuticals Industries Ltd. | Spaced drug delivery system |
PT1377276E (pt) * | 2001-04-10 | 2011-12-30 | Sun Pharma Advanced Res Co Ltd | Composição de libertação temporizada por pulso |
TW200303919A (en) * | 2001-12-05 | 2003-09-16 | Hiroyuki Ohno | Cytotoxic protein and the use |
NO20021592D0 (no) | 2002-04-04 | 2002-04-04 | Fmc Biopolymer As | Polysakkaridkapsler og fremgangsmåte ved fremstilling derav |
KR100592511B1 (ko) * | 2002-12-30 | 2006-07-03 | 안경섭 | 벤즈이미다졸 유도체 또는 약리학적으로 허용되는 이의염을 활성물질로 하는 안정성이 강화된 방출제어형 제제및 그 제조방법 |
BRPI0409652A (pt) | 2003-04-24 | 2006-04-25 | Jagotec Ag | tablete, embalagem farmacêutica, método de tratamento de doenças, e, método de preparação de um tablete |
TWI372066B (en) | 2003-10-01 | 2012-09-11 | Wyeth Corp | Pantoprazole multiparticulate formulations |
KR100645019B1 (ko) * | 2004-06-03 | 2006-11-14 | 주식회사 리젠 바이오텍 | 비수용성 무기화합물이 포집되어 있는 고분자 비드, 이의제조방법 및 용도 |
EP1846042A2 (en) * | 2005-01-05 | 2007-10-24 | Board of Regents, The University of Texas System | Conjugates for dual imaging and radiochemotherapy: composition, manufacturing, and applications |
EP1909765A1 (en) * | 2005-07-22 | 2008-04-16 | Dow Gloval Technologies Inc. | Oral drug compliance monitoring using sound detection |
EP1916995B2 (en) | 2005-07-29 | 2022-06-29 | Stichting Groningen Centre for Drug Research | Ph-controlled pulsatile delivery system, methods for preparation and use thereof |
US8679545B2 (en) | 2005-11-12 | 2014-03-25 | The Regents Of The University Of California | Topical corticosteroids for the treatment of inflammatory diseases of the gastrointestinal tract |
US8497258B2 (en) | 2005-11-12 | 2013-07-30 | The Regents Of The University Of California | Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract |
US8324192B2 (en) | 2005-11-12 | 2012-12-04 | The Regents Of The University Of California | Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract |
JP5372525B2 (ja) | 2006-03-03 | 2013-12-18 | エフ エム シー コーポレーション | カプセルの製造方法および該製造方法により製造されるカプセル |
JP2007284483A (ja) * | 2006-04-13 | 2007-11-01 | Daito Kasei Kogyo Kk | 吸湿性顔料およびそれを含有する化粧料 |
JP2009537548A (ja) * | 2006-05-19 | 2009-10-29 | アダマス・ファーマシューティカルズ・インコーポレーテッド | ウイルス感染症の治療のための方法および組成物 |
UA96457C2 (ru) | 2006-08-03 | 2011-11-10 | Нитек Фарма Аг | Лечение ревматоидного артрита глюкокортикоидами с отсроченным высвобождением |
WO2008044236A2 (en) * | 2006-10-10 | 2008-04-17 | Dexcel Pharma Technologies Ltd. | Improved release of statins in the intestine |
US8865692B2 (en) | 2007-11-13 | 2014-10-21 | Meritage Pharma, Inc | Compositions for the treatment of gastrointestinal inflammation |
HUE038452T2 (hu) | 2007-11-13 | 2018-10-29 | Meritage Pharma Inc | Gyomor és bélrendszeri gyulladások kezelésére szolgáló kompozíciók |
US20090264392A1 (en) * | 2008-04-21 | 2009-10-22 | Meritage Pharma, Inc. | Treating eosinophilic esophagitis |
EP2179727B1 (en) * | 2008-10-27 | 2013-05-29 | Roquette Freres | Water insoluble polymer: modified starch derivative-based film coatings for colon targeting |
BR112013029199B1 (pt) | 2011-05-13 | 2022-02-08 | Eb Ip Hybritabs B.V. | Dispositivo de distribuição de dois fármacos |
AU2014373683B2 (en) | 2013-12-31 | 2020-05-07 | Rapamycin Holdings, Llc | Oral rapamycin nanoparticle preparations and use |
ES2841248T3 (es) | 2014-02-21 | 2021-07-07 | Principia Biopharma Inc | Sales y forma sólida de un inhibidor de BTK |
EP3131546B1 (en) | 2014-04-16 | 2022-02-16 | Rapamycin Holdings, Inc. | Oral rapamycin preparation for use in treating feline chronic gingivo- stomatitis (fcgs) |
CA2970723C (en) | 2014-12-18 | 2023-09-05 | Principia Biopharma Inc. | Treatment of pemphigus |
EP3236953B1 (en) * | 2014-12-24 | 2020-11-11 | Principia Biopharma Inc. | Site specific dosing of a btk inhibitor |
TW201718572A (zh) | 2015-06-24 | 2017-06-01 | 普林斯匹亞生物製藥公司 | 酪胺酸激酶抑制劑 |
GB201511284D0 (en) * | 2015-06-26 | 2015-08-12 | Univ Witwatersrand Jhb | An oral pharmaceutical dosage form for the delivery of a peptide and/or protein |
CN105434403A (zh) * | 2015-12-30 | 2016-03-30 | 成都医学院 | 一种溴吡斯的明包衣缓释微丸及其制备方法 |
EP3478273A1 (en) | 2016-06-29 | 2019-05-08 | Principia Biopharma Inc. | Modified release formulations of 2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile |
JP6780412B2 (ja) * | 2016-09-28 | 2020-11-04 | ライオン株式会社 | コーティング組成物ならびにコーティング製剤及びその製造方法 |
CN112544964B (zh) * | 2020-12-28 | 2024-03-19 | 苏州大学 | 一种可服用胶囊及其制备方法与应用 |
CN115176879B (zh) * | 2022-09-09 | 2022-11-18 | 山东新和成氨基酸有限公司 | 一种过瘤胃蛋氨酸的制备方法 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8518301D0 (en) * | 1985-07-19 | 1985-08-29 | Fujisawa Pharmaceutical Co | Hydrodynamically explosive systems |
GB8628359D0 (en) * | 1986-11-27 | 1986-12-31 | Zyma Sa | Galenical formulation |
US4891223A (en) * | 1987-09-03 | 1990-01-02 | Air Products And Chemicals, Inc. | Controlled release delivery coating formulation for bioactive substances |
EP0408496A3 (en) * | 1989-07-12 | 1992-07-01 | Ciba-Geigy Ag | Solid dosage form for pharmaceutical substances |
US5229131A (en) * | 1990-02-05 | 1993-07-20 | University Of Michigan | Pulsatile drug delivery system |
NZ242065A (en) * | 1991-03-26 | 1996-06-25 | Csl Ltd | Delayed release implant having a degradable or rupturable polymeric coating |
US5260069A (en) * | 1992-11-27 | 1993-11-09 | Anda Sr Pharmaceuticals Inc. | Pulsatile particles drug delivery system |
US5500227A (en) * | 1993-11-23 | 1996-03-19 | Euro-Celtique, S.A. | Immediate release tablet cores of insoluble drugs having sustained-release coating |
ES2082723B1 (es) * | 1994-07-20 | 1996-10-01 | Lilly Sa | Formulacion farmaceutica de fluoxetina en forma dispersable. |
US5534263A (en) * | 1995-02-24 | 1996-07-09 | Alza Corporation | Active agent dosage form comprising a matrix and at least two insoluble bands |
US5945124A (en) * | 1995-07-05 | 1999-08-31 | Byk Gulden Chemische Fabrik Gmbh | Oral pharmaceutical composition with delayed release of active ingredient for pantoprazole |
DE19603019C2 (de) * | 1996-01-17 | 1998-10-15 | Lancaster Group Gmbh | Kosmetisches Hautreinigungsmittel auf Basis natürlicher Wirkstoffe |
US5840332A (en) * | 1996-01-18 | 1998-11-24 | Perio Products Ltd. | Gastrointestinal drug delivery system |
JP2000053316A (ja) * | 1998-08-06 | 2000-02-22 | Sony Corp | フィルム剥離装置 |
-
1998
- 1998-10-01 WO PCT/US1998/020779 patent/WO1999018938A1/en not_active Application Discontinuation
- 1998-10-01 ES ES98949742T patent/ES2198756T3/es not_active Expired - Lifetime
- 1998-10-01 CA CA002305762A patent/CA2305762C/en not_active Expired - Fee Related
- 1998-10-01 TR TR2000/00944T patent/TR200000944T2/xx unknown
- 1998-10-01 DE DE69814122T patent/DE69814122T2/de not_active Expired - Lifetime
- 1998-10-01 KR KR1020007003850A patent/KR20010031034A/ko not_active Application Discontinuation
- 1998-10-01 BR BR9815240-8A patent/BR9815240A/pt not_active IP Right Cessation
- 1998-10-01 AT AT98949742T patent/ATE238774T1/de active
- 1998-10-01 CZ CZ20001256A patent/CZ301028B6/cs not_active IP Right Cessation
- 1998-10-01 JP JP2000515574A patent/JP2001519379A/ja active Pending
- 1998-10-01 DK DK98949742T patent/DK1021171T3/da active
- 1998-10-01 HU HU0004945A patent/HUP0004945A3/hu unknown
- 1998-10-01 IL IL135502A patent/IL135502A/en not_active IP Right Cessation
- 1998-10-01 NZ NZ503820A patent/NZ503820A/en unknown
- 1998-10-01 CN CNB988099853A patent/CN100548279C/zh not_active Expired - Fee Related
- 1998-10-01 PT PT98949742T patent/PT1021171E/pt unknown
- 1998-10-01 PL PL339861A patent/PL203733B1/pl not_active IP Right Cessation
- 1998-10-01 AU AU96001/98A patent/AU740757B2/en not_active Ceased
- 1998-10-01 EP EP98949742A patent/EP1021171B1/en not_active Expired - Lifetime
-
2000
- 2000-04-07 NO NO20001829A patent/NO20001829L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CN100548279C (zh) | 2009-10-14 |
HUP0004945A2 (hu) | 2001-08-28 |
AU740757B2 (en) | 2001-11-15 |
NO20001829D0 (no) | 2000-04-07 |
HUP0004945A3 (en) | 2005-03-29 |
ES2198756T3 (es) | 2004-02-01 |
TR200000944T2 (tr) | 2000-11-21 |
PL339861A1 (en) | 2001-01-15 |
CZ301028B6 (cs) | 2009-10-14 |
EP1021171B1 (en) | 2003-05-02 |
NZ503820A (en) | 2004-02-27 |
CZ20001256A3 (cs) | 2000-10-11 |
PL203733B1 (pl) | 2009-11-30 |
CA2305762C (en) | 2006-09-26 |
WO1999018938A1 (en) | 1999-04-22 |
BR9815240A (pt) | 2001-10-30 |
AU9600198A (en) | 1999-05-03 |
EP1021171A1 (en) | 2000-07-26 |
KR20010031034A (ko) | 2001-04-16 |
CN1274280A (zh) | 2000-11-22 |
IL135502A0 (en) | 2001-05-20 |
DK1021171T3 (da) | 2003-08-25 |
DE69814122D1 (de) | 2003-06-05 |
DE69814122T2 (de) | 2004-03-18 |
JP2001519379A (ja) | 2001-10-23 |
CA2305762A1 (en) | 1999-04-22 |
IL135502A (en) | 2006-07-05 |
ATE238774T1 (de) | 2003-05-15 |
NO20001829L (no) | 2000-06-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PT1021171E (pt) | Sistema de administracao de farmacos no tracto gastrointestinal de libertacao total prolongada | |
IL146708A0 (en) | Delayed total release two pulse gastrointestinal drug delivery system | |
MY133883A (en) | Gastrointestinal drug delivery system | |
US4898733A (en) | Layered, compression molded device for the sustained release of a beneficial agent | |
DK0673645T3 (da) | Farmaceutisk præparat til afgivelse af lægemidler i colon | |
ES2149250T3 (es) | Dispositivo para la administracion de medicamentos con liberacion controlada. | |
ATE269709T1 (de) | Tablette mit verzögerter freigabe enthaltend einen blutzuckersenkenden wirkstoff und einen antihyperglyzemischen wirkstoff | |
GT199900151A (es) | Sistema de entrega controlado de droga administrado oralmente, que provee control temporal y espacial. | |
IE872110L (en) | Oral therapeutic system having systemic action | |
DE60237372D1 (de) | Magenretentionssystem mit kontrollierter arzneimittelfreisetzung | |
CY1108665T1 (el) | Διαταξεις χορηγησης φαρμακων παρατεταμενης απελευθερωσης, μεθοδοι χρησης και μεθοδοι κατασκευης αυτων | |
GB2338414A (en) | Intravesical drug delivery system | |
WO2002078601A8 (en) | Drug release from polymer matrices through mechanical stimulation | |
DK1133269T3 (da) | Kontrolleret afgivelsesindretning til indgift af terapeutika i det indre öre | |
PT706401E (pt) | Sistema para administracao de farmacos | |
AU7465087A (en) | Controlled release bioerodible drug delivery system | |
DE3770937D1 (de) | Tablette zur pharmazeutischen anwendung sukzessiver freisetzung. | |
NO995313L (no) | Mikroartikler nyttige som ultrasoniske kontrastmidler og til levering av legemidler i blodbanen | |
CA2243863A1 (en) | Gastrointestinal drug delivery system |