DK1133269T3 - Kontrolleret afgivelsesindretning til indgift af terapeutika i det indre öre - Google Patents
Kontrolleret afgivelsesindretning til indgift af terapeutika i det indre öreInfo
- Publication number
- DK1133269T3 DK1133269T3 DK99965987T DK99965987T DK1133269T3 DK 1133269 T3 DK1133269 T3 DK 1133269T3 DK 99965987 T DK99965987 T DK 99965987T DK 99965987 T DK99965987 T DK 99965987T DK 1133269 T3 DK1133269 T3 DK 1133269T3
- Authority
- DK
- Denmark
- Prior art keywords
- inner ear
- therapeutic agents
- drug delivery
- ear
- round window
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0046—Ear
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F11/00—Methods or devices for treatment of the ears or hearing sense; Non-electric hearing aids; Methods or devices for enabling ear patients to achieve auditory perception through physiological senses other than hearing sense; Protective devices for the ears, carried on the body or in the hand
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Acoustics & Sound (AREA)
- Biophysics (AREA)
- Otolaryngology (AREA)
- Psychology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/205,251 US8197461B1 (en) | 1998-12-04 | 1998-12-04 | Controlled release system for delivering therapeutic agents into the inner ear |
PCT/US1999/028716 WO2000033775A1 (en) | 1998-12-04 | 1999-12-03 | Controlled release system for delivering therapeutic agents into the inner ear |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1133269T3 true DK1133269T3 (da) | 2007-06-11 |
Family
ID=22761443
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK99965987T DK1133269T3 (da) | 1998-12-04 | 1999-12-03 | Kontrolleret afgivelsesindretning til indgift af terapeutika i det indre öre |
Country Status (10)
Country | Link |
---|---|
US (2) | US8197461B1 (da) |
EP (2) | EP1133269B1 (da) |
AT (1) | ATE353615T1 (da) |
AU (1) | AU761837B2 (da) |
CA (1) | CA2350838C (da) |
DE (1) | DE69935155T2 (da) |
DK (1) | DK1133269T3 (da) |
ES (1) | ES2283146T3 (da) |
PT (1) | PT1133269E (da) |
WO (1) | WO2000033775A1 (da) |
Families Citing this family (94)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8795242B2 (en) | 1994-05-13 | 2014-08-05 | Kensey Nash Corporation | Resorbable polymeric device for localized drug delivery |
US7963997B2 (en) * | 2002-07-19 | 2011-06-21 | Kensey Nash Corporation | Device for regeneration of articular cartilage and other tissue |
US8697108B2 (en) * | 1994-05-13 | 2014-04-15 | Kensey Nash Corporation | Method for making a porous polymeric material |
US8197461B1 (en) | 1998-12-04 | 2012-06-12 | Durect Corporation | Controlled release system for delivering therapeutic agents into the inner ear |
US20060241075A1 (en) * | 2001-05-18 | 2006-10-26 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of desmoglein gene expression using short interfering nucleic acid (siNA) |
US20050282188A1 (en) * | 2001-05-18 | 2005-12-22 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of gene expression using short interfering nucleic acid (siNA) |
US20070042983A1 (en) * | 2001-05-18 | 2007-02-22 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of gene expression using short interfering nucleic acid (siNA) |
US20050222066A1 (en) * | 2001-05-18 | 2005-10-06 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA) |
US20080161256A1 (en) * | 2001-05-18 | 2008-07-03 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of gene expression using short interfering nucleic acid (siNA) |
US7517864B2 (en) * | 2001-05-18 | 2009-04-14 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA) |
US20070270579A1 (en) * | 2001-05-18 | 2007-11-22 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of gene expression using short interfering nucleic acid (siNA) |
ES2271278T3 (es) * | 2001-06-18 | 2007-04-16 | Durect Corporation | Dispositivo para administrar microdosis de agentes en el oido. |
US7206639B2 (en) * | 2002-03-15 | 2007-04-17 | Sarcos Investments Lc | Cochlear drug delivery system and method |
AU2002331830A1 (en) | 2002-09-06 | 2004-03-29 | Durect Corporation | Delivery of modulators of glutamate-mediated neurotransmission to the inner ear |
EP1438942A1 (en) | 2003-01-17 | 2004-07-21 | Schering Oy | An otorhinological drug delivery device |
DE10305349A1 (de) | 2003-02-10 | 2004-08-26 | Cell Center Cologne Gmbh | Innenohr-Steckverbindung |
US8940321B2 (en) | 2003-12-12 | 2015-01-27 | Otic Pharma Ltd. | Compositions for treatment of ear disorders and methods of use thereof |
CA2548892C (en) | 2003-12-12 | 2015-10-27 | Eran Eilat | Compositions for treatment of ear disorders and methods of use thereof |
US7351246B2 (en) * | 2004-01-20 | 2008-04-01 | Epley John M | Minimally invasive, sustained, intra-tympanic drug delivery system |
US7867194B2 (en) | 2004-01-29 | 2011-01-11 | The Charles Stark Draper Laboratory, Inc. | Drug delivery apparatus |
WO2005072793A1 (en) * | 2004-01-29 | 2005-08-11 | The Charles Stark Draper Laboratory, Inc. | Implantable drug delivery apparatus |
US7668325B2 (en) | 2005-05-03 | 2010-02-23 | Earlens Corporation | Hearing system having an open chamber for housing components and reducing the occlusion effect |
EP1861161A4 (en) * | 2005-01-24 | 2012-05-16 | Neurosystec Corp | APPARATUS AND METHOD FOR DISPENSING THERAPEUTIC AND / OR OTHER AGENTS IN THE INTERNAL EAR AND OTHER FABRICS |
US20070077270A1 (en) * | 2005-03-28 | 2007-04-05 | Clemson University | Delivery devices and methods for long-term, targeted delivery of therapeutic agents to the eye and ear |
CA2613050A1 (en) * | 2005-06-20 | 2007-01-04 | Abbeymoor Medical, Inc. | Self-adjusting endourethral device & methods of use |
US20070110788A1 (en) * | 2005-11-14 | 2007-05-17 | Hissong James B | Injectable formulation capable of forming a drug-releasing device |
US20110184387A1 (en) * | 2010-01-22 | 2011-07-28 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Compositions and methods for therapeutic delivery with microorganisms |
DK3326681T3 (da) * | 2005-12-30 | 2019-09-30 | Rdd Pharma Ltd | Indretning til behandling af analsphincteren |
US8267905B2 (en) * | 2006-05-01 | 2012-09-18 | Neurosystec Corporation | Apparatus and method for delivery of therapeutic and other types of agents |
US20070264296A1 (en) * | 2006-05-10 | 2007-11-15 | Myntti Matthew F | Biofilm extracellular polysachharide solvating system |
US7959943B2 (en) * | 2006-05-10 | 2011-06-14 | Medtronics Xomed, Inc. | Solvating system and sealant for medical use in the middle or inner ear |
US7993675B2 (en) | 2006-05-10 | 2011-08-09 | Medtronic Xomed, Inc. | Solvating system and sealant for medical use in the sinuses and nasal passages |
US7976873B2 (en) * | 2006-05-10 | 2011-07-12 | Medtronic Xomed, Inc. | Extracellular polysaccharide solvating system for treatment of bacterial ear conditions |
US7803148B2 (en) * | 2006-06-09 | 2010-09-28 | Neurosystec Corporation | Flow-induced delivery from a drug mass |
JP2010511595A (ja) * | 2006-07-31 | 2010-04-15 | ニューロシステック コーポレイション | 遊離塩基ガシクリジンナノ粒子 |
US9046192B2 (en) * | 2007-01-31 | 2015-06-02 | The Charles Stark Draper Laboratory, Inc. | Membrane-based fluid control in microfluidic devices |
US8088095B2 (en) * | 2007-02-08 | 2012-01-03 | Medtronic Xomed, Inc. | Polymeric sealant for medical use |
WO2009006390A2 (en) | 2007-07-03 | 2009-01-08 | Charles Stark Draper Laboratory, Inc. | Drug-eluting staples prosthesis |
WO2009049320A1 (en) | 2007-10-12 | 2009-04-16 | Earlens Corporation | Multifunction system and method for integrated hearing and communiction with noise cancellation and feedback management |
US7951393B2 (en) * | 2007-11-14 | 2011-05-31 | Canaan Vernon Lavelle Harris | Keloid therapy |
US20090181068A1 (en) | 2008-01-14 | 2009-07-16 | Dunn Richard L | Low Viscosity Liquid Polymeric Delivery System |
CN101264043B (zh) * | 2008-01-14 | 2010-09-08 | 四川大学 | 耳穴定位粘药器 |
KR20130097813A (ko) * | 2008-04-21 | 2013-09-03 | 오토노미, 인코포레이티드 | 귀 질환 및 병태를 치료하기 위한 귀 조제물 |
US11969501B2 (en) | 2008-04-21 | 2024-04-30 | Dompé Farmaceutici S.P.A. | Auris formulations for treating otic diseases and conditions |
WO2009152374A2 (en) | 2008-06-12 | 2009-12-17 | Medtronic Xomed, Inc. | Method for treating chronic wounds |
DK2301261T3 (da) | 2008-06-17 | 2019-04-23 | Earlens Corp | Optiske elektromekaniske høreapparater med separate strømforsynings- og signalkomponenter |
US8496957B2 (en) | 2008-07-21 | 2013-07-30 | Otonomy, Inc | Controlled release auris sensory cell modulator compositions and methods for the treatment of otic disorders |
DK3509324T3 (da) | 2008-09-22 | 2023-10-02 | Earlens Corp | Balancerede armaturindretninger og fremgangsmåder til at høre |
US20100086576A1 (en) * | 2008-10-06 | 2010-04-08 | Myntti Matthew F | Antimicrobial composition and methods of making and using same |
US8808317B2 (en) * | 2008-11-06 | 2014-08-19 | Carl Braunagel | Apparatus for cleaning a nasal cavity |
US9078783B2 (en) * | 2008-12-24 | 2015-07-14 | Acclarent, Inc. | Silent effusion removal |
SE534532C2 (sv) * | 2009-01-22 | 2011-09-27 | Svante Syk-Eksell | Expanderande propp avsedd för insättning i en näsborre/örongång och för distribuering av medicinska preparat |
EP2445481B1 (en) * | 2009-06-18 | 2017-03-22 | Rdd Pharma Ltd. | Methods and devices for delivery of pharmaceutical agents within orifices of the body |
NZ599524A (en) | 2009-11-09 | 2014-04-30 | Spotlight Technology Partners Llc | Polysaccharide based hydrogels |
US8795727B2 (en) | 2009-11-09 | 2014-08-05 | Spotlight Technology Partners Llc | Fragmented hydrogels |
WO2011107932A1 (en) * | 2010-03-01 | 2011-09-09 | Estimme Ltd. | Drug delivery device |
WO2012088187A2 (en) | 2010-12-20 | 2012-06-28 | SoundBeam LLC | Anatomically customized ear canal hearing apparatus |
EP2670456B1 (en) | 2011-02-02 | 2019-12-18 | The Charles Stark Draper Laboratory, Inc. | Drug delivery apparatus |
US8911424B2 (en) * | 2011-02-09 | 2014-12-16 | Ethicon, Inc. | Methods and devices for preventing catheter related urinary tract infections |
WO2012154953A2 (en) | 2011-05-10 | 2012-11-15 | Microbial Defense Systems, Llc | Antimicrobial solid and methods of making and using same |
DE102011107139A1 (de) * | 2011-07-12 | 2013-01-17 | Gerd Borkowski | Hörgerät mit zumindest einem in den Gehörgang einzuführenden Abschnitt |
CN103781506B (zh) | 2011-08-05 | 2016-08-31 | 尤尼特拉克特注射器私人有限公司 | 在药物至目标位置的给药中使用的套管及制造套管的方法 |
CA2848730A1 (en) * | 2011-09-15 | 2013-03-21 | Yoseph Yaacobi | Systems and methods for treating ear disorders |
US8685106B2 (en) | 2011-11-15 | 2014-04-01 | Abraham Lin | Method of a pharmaceutical delivery system for use within a joint replacement |
US20140309597A1 (en) * | 2012-10-15 | 2014-10-16 | Jeremiah Joseph Lowney | Applicator for delivering a single dose of medicine to an inner canal of an ear |
EP2931196A4 (en) * | 2012-12-14 | 2016-07-13 | Univ Columbia | SYSTEM AND METHOD FOR LOCAL ADMINISTRATION OF A THERAPEUTIC AGENT IN THE INTERNAL EAR |
US10821276B2 (en) | 2012-12-14 | 2020-11-03 | The Trustees Of Columbia University In The City Of New York | System and method to locally deliver therapeutic agent to inner ear |
US20150182382A1 (en) * | 2013-12-27 | 2015-07-02 | Custom Protect Ear, Inc. | Pre-lubricated earplugs and the method of production thereof |
US10034103B2 (en) | 2014-03-18 | 2018-07-24 | Earlens Corporation | High fidelity and reduced feedback contact hearing apparatus and methods |
US9616207B2 (en) * | 2014-06-26 | 2017-04-11 | Cochlear Limited | Treatment of the ear |
EP3169396B1 (en) | 2014-07-14 | 2021-04-21 | Earlens Corporation | Sliding bias and peak limiting for optical hearing devices |
US9924276B2 (en) | 2014-11-26 | 2018-03-20 | Earlens Corporation | Adjustable venting for hearing instruments |
AU2016304585B2 (en) * | 2015-08-05 | 2023-04-06 | Children's Medical Center Corporation | Compositions with permeation enhancers for drug delivery |
DK3355801T3 (da) | 2015-10-02 | 2021-06-21 | Earlens Corp | Tilpasset øregangsindretning til lægemiddelafgivelse |
US10306381B2 (en) | 2015-12-30 | 2019-05-28 | Earlens Corporation | Charging protocol for rechargable hearing systems |
US11350226B2 (en) | 2015-12-30 | 2022-05-31 | Earlens Corporation | Charging protocol for rechargeable hearing systems |
US10492010B2 (en) | 2015-12-30 | 2019-11-26 | Earlens Corporations | Damping in contact hearing systems |
US11213430B2 (en) | 2016-05-26 | 2022-01-04 | Cochlear Limited | Inner ear plug |
WO2017223193A1 (en) * | 2016-06-22 | 2017-12-28 | The Charles Stark Draper Laboratory Inc. | A system for inner ear drug delivery via trans-round window membrane injection |
EP3493779A1 (en) * | 2016-08-05 | 2019-06-12 | Tusker Medical, Inc. | Systems, apparatus, and methods for delivery of therapeutic substance to the middle and/or inner ear |
WO2018048794A1 (en) | 2016-09-09 | 2018-03-15 | Earlens Corporation | Contact hearing systems, apparatus and methods |
WO2018093733A1 (en) | 2016-11-15 | 2018-05-24 | Earlens Corporation | Improved impression procedure |
US20180221208A1 (en) * | 2017-02-08 | 2018-08-09 | Tusker Medical, Inc. | Systems, apparatus, and methods for delivery of therapeutic substance to the tympanic membrane |
EP3694579A4 (en) * | 2017-10-12 | 2021-07-07 | Cochlear Limited | CLINICAL-BASED AUTOMATED DELIVERY OF TREATMENT SUBSTANCES TO THE INTERNAL EAR |
WO2019136133A1 (en) | 2018-01-03 | 2019-07-11 | The Trustees Of Columbia University In The City Of New York | Microneedle for local delivery of therapeutic agent |
JP7273830B2 (ja) | 2018-01-16 | 2023-05-15 | タスカー メディカル,インコーポレイテッド | 耳下手術のための可視化デバイス |
WO2019173470A1 (en) | 2018-03-07 | 2019-09-12 | Earlens Corporation | Contact hearing device and retention structure materials |
WO2019199680A1 (en) | 2018-04-09 | 2019-10-17 | Earlens Corporation | Dynamic filter |
EP3781102A1 (en) * | 2018-04-19 | 2021-02-24 | Spiral Therapeutics, Inc. | Inner ear drug delivery devices and methods of use |
EP3840827A4 (en) * | 2018-08-24 | 2022-05-18 | Cochlear Limited | MASS TRANSPORT WITHIN MAMMALS |
US20220032020A1 (en) * | 2018-12-05 | 2022-02-03 | Cochlear Limited | Therapeutic substance storage and delivery |
JP2023512193A (ja) | 2020-01-24 | 2023-03-24 | スパイラル・セラピューティクス・インコーポレイテッド | 耳科学および他の用途のための視覚化デバイス、システム、および方法 |
WO2022081955A1 (en) * | 2020-10-15 | 2022-04-21 | The Board Of Trustees Of The Leland Stanford Junior University | Method and system for ototopical delivery using nanoparticles for ear infection diagnosis and treatment |
EP4183380A1 (en) * | 2021-11-22 | 2023-05-24 | Medizinische Hochschule Hannover | Patient-specific, drug releasing, compressible implant with in-tegrated handle for insertion into a body cavity and method for its manufacture |
Family Cites Families (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE850341C (de) | 1950-04-15 | 1952-09-25 | Gazzoni & Co A | Vorrichtung zum Benetzen des aeusseren Gehoerganges mit einer schmerzstillenden Fluessigkeit |
GB1204117A (en) | 1966-09-08 | 1970-09-03 | Syntex Corp | Devices and methods for administering pharmaceutical preparations |
US3982545A (en) | 1974-08-22 | 1976-09-28 | Herbert Silverstein | Middle ear aeration and implant |
US4034759A (en) | 1975-08-27 | 1977-07-12 | Xomed, Inc. | Moisture-expandable prosthesis |
US4141973A (en) | 1975-10-17 | 1979-02-27 | Biotrics, Inc. | Ultrapure hyaluronic acid and the use thereof |
US4159719A (en) | 1977-05-09 | 1979-07-03 | Xomed, Inc. | Moisture-expandable ear wick |
GB2042888B (en) | 1979-03-05 | 1983-09-28 | Teijin Ltd | Preparation for administration to the mucosa of the oral or nasal cavity |
US4360019A (en) | 1979-02-28 | 1982-11-23 | Andros Incorporated | Implantable infusion device |
US4343931A (en) | 1979-12-17 | 1982-08-10 | Minnesota Mining And Manufacturing Company | Synthetic absorbable surgical devices of poly(esteramides) |
US4297748A (en) | 1980-01-02 | 1981-11-03 | Moloy Peter J | Middle ear balloon |
US4692147A (en) | 1980-04-02 | 1987-09-08 | Medtronic, Inc. | Drug administration device |
US5166331A (en) | 1983-10-10 | 1992-11-24 | Fidia, S.P.A. | Hyaluronics acid fractions, methods for the preparation thereof, and pharmaceutical compositions containing same |
US4487603A (en) | 1982-11-26 | 1984-12-11 | Cordis Corporation | Implantable microinfusion pump system |
US4472394A (en) * | 1983-09-19 | 1984-09-18 | G. D. Searle & Co. | Method for increasing weight in domestic animals |
US4784640A (en) * | 1984-08-20 | 1988-11-15 | Johnson Ronald F | Apparatus for implanting implants in cattle |
US4725852A (en) | 1985-05-09 | 1988-02-16 | Burlington Industries, Inc. | Random artificially perturbed liquid apparatus and method |
US4851402A (en) * | 1987-02-27 | 1989-07-25 | International Minerals & Chemical Corp. | Estriol growth promotant |
US4874368A (en) | 1988-07-25 | 1989-10-17 | Micromedics, Inc. | Fibrin glue delivery system |
US5350580A (en) | 1990-03-05 | 1994-09-27 | Minnesota Mining And Manufacturing Company | Device and method for extended delivery of pharmacologically active agents to the ear |
US5236413B1 (en) | 1990-05-07 | 1996-06-18 | Andrew J Feiring | Method and apparatus for inducing the permeation of medication into internal tissue |
US5437656A (en) | 1991-02-27 | 1995-08-01 | Leonard Bloom | Method and device for inhibiting H.I.V. hepatitis B and other viruses and germs when using a needle, scalpel and other sharp instrument in a medical environment |
US5695458A (en) | 1991-02-27 | 1997-12-09 | Maryland Biopolymer Technologies, Llc | Anti-infective polymer-iodine coating for blood collection and delivery systems |
AU1579092A (en) | 1991-02-27 | 1992-10-06 | Nova Pharmaceutical Corporation | Anti-infective and anti-inflammatory releasing systems for medical devices |
US5344411A (en) | 1991-02-27 | 1994-09-06 | Leonard Bloom | Method and device for inhibiting HIV, hepatitis B and other viruses and germs when using a catheter in a medical environment |
US5304134A (en) | 1992-01-17 | 1994-04-19 | Danforth Biomedical, Inc. | Lubricious yet bondable catheter channel sleeve for over-the-wire catheters |
US5461140A (en) | 1992-04-30 | 1995-10-24 | Pharmaceutical Delivery Systems | Bioerodible polymers for solid controlled release pharmaceutical compositions |
US5419312A (en) | 1993-04-20 | 1995-05-30 | Wildflower Communications, Inc. | Multi-function endoscope apparatus |
US5421818A (en) | 1993-10-18 | 1995-06-06 | Inner Ear Medical Delivery Systems, Inc. | Multi-functional inner ear treatment and diagnostic system |
DE19509029C2 (de) | 1994-06-06 | 1999-11-11 | Ford Werke Ag | Verfahren zur Herstellung einer katalytischen Behandlungsvorrichtung |
US6239116B1 (en) | 1994-07-15 | 2001-05-29 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
US5572594A (en) | 1994-09-27 | 1996-11-05 | Devoe; Lambert | Ear canal device holder |
US5736524A (en) | 1994-11-14 | 1998-04-07 | Merck & Co.,. Inc. | Polynucleotide tuberculosis vaccine |
DE19549506C2 (de) * | 1995-03-07 | 1998-07-30 | Richard Prof Dr Sueverkruep | Darreichungsform zur äußerlichen Applikation und Verfahren zur Herstellung derselben |
WO1997000067A1 (en) | 1995-06-15 | 1997-01-03 | University Of Victoria Innovation And Development | Mycobacterium tuberculosis dna sequences encoding immunostimulatory peptides |
WO1997038698A1 (en) | 1996-04-18 | 1997-10-23 | University Technology Corporation | Methods for treating middle and inner ear disorders |
US5954682A (en) | 1996-09-25 | 1999-09-21 | Advanced Medical Instruments | Therapeutic applicator apparatus and method |
US6045528A (en) | 1997-06-13 | 2000-04-04 | Intraear, Inc. | Inner ear fluid transfer and diagnostic system |
JP2001516767A (ja) * | 1997-09-24 | 2001-10-02 | アムジエン・インコーポレーテツド | 感覚神経向性化合物を使用する難聴の予防及び治療法 |
US6177434B1 (en) * | 1997-12-16 | 2001-01-23 | The United States Of America As Represented By The Secretary Of The Navy | Prevention or reversal of sensorineural hearing loss (SNHL) through biologic mechanisms |
US6440102B1 (en) | 1998-07-23 | 2002-08-27 | Durect Corporation | Fluid transfer and diagnostic system for treating the inner ear |
US8197461B1 (en) | 1998-12-04 | 2012-06-12 | Durect Corporation | Controlled release system for delivering therapeutic agents into the inner ear |
-
1998
- 1998-12-04 US US09/205,251 patent/US8197461B1/en not_active Expired - Fee Related
-
1999
- 1999-12-03 DE DE69935155T patent/DE69935155T2/de not_active Expired - Lifetime
- 1999-12-03 DK DK99965987T patent/DK1133269T3/da active
- 1999-12-03 US US09/831,487 patent/US6685697B1/en not_active Expired - Lifetime
- 1999-12-03 EP EP99965987A patent/EP1133269B1/en not_active Expired - Lifetime
- 1999-12-03 AU AU21646/00A patent/AU761837B2/en not_active Ceased
- 1999-12-03 CA CA002350838A patent/CA2350838C/en not_active Expired - Fee Related
- 1999-12-03 WO PCT/US1999/028716 patent/WO2000033775A1/en active IP Right Grant
- 1999-12-03 EP EP06024761A patent/EP1767175A1/en not_active Withdrawn
- 1999-12-03 AT AT99965987T patent/ATE353615T1/de active
- 1999-12-03 PT PT99965987T patent/PT1133269E/pt unknown
- 1999-12-03 ES ES99965987T patent/ES2283146T3/es not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP1133269B1 (en) | 2007-02-14 |
EP1767175A1 (en) | 2007-03-28 |
ATE353615T1 (de) | 2007-03-15 |
ES2283146T3 (es) | 2007-10-16 |
US8197461B1 (en) | 2012-06-12 |
CA2350838C (en) | 2008-12-02 |
CA2350838A1 (en) | 2000-06-15 |
AU761837B2 (en) | 2003-06-12 |
EP1133269A1 (en) | 2001-09-19 |
PT1133269E (pt) | 2007-05-31 |
WO2000033775A1 (en) | 2000-06-15 |
AU2164600A (en) | 2000-06-26 |
DE69935155D1 (de) | 2007-03-29 |
DE69935155T2 (de) | 2007-10-31 |
US6685697B1 (en) | 2004-02-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK1133269T3 (da) | Kontrolleret afgivelsesindretning til indgift af terapeutika i det indre öre | |
ATE444768T1 (de) | Wirkstoffabgabesysteme | |
HUP0300491A2 (en) | Improvements in or relating to the delivery of oral drugs | |
HUP9802773A2 (en) | Transcorneal drug-release system | |
WO2004010975A3 (en) | Controlled drug delivery | |
DK1083879T3 (da) | Indretninger til at tilvejebringe forlænget medikamentterapi | |
BRPI0406486A (pt) | Dispositivo de administração para medicamento fluido | |
NO20034684D0 (no) | Innretning for administrering av midler gjennom stratum corcum | |
CY1108665T1 (el) | Διαταξεις χορηγησης φαρμακων παρατεταμενης απελευθερωσης, μεθοδοι χρησης και μεθοδοι κατασκευης αυτων | |
WO2000020056A8 (en) | Patient controlled fluid delivery device | |
HUP0004945A2 (hu) | Gyomor-bélrendszerben késleltetett teljes hatóanyag-kibocsátást biztosító hatóanyag-célbajuttató rendszer | |
WO2004087011A3 (en) | Therapeutic agent delivery device with controlled therapeutic agent release rates | |
EE05506B1 (et) | Ravimi manustamise vahend eriti progestiinide jastrogeenide manustamiseks | |
ES2149250T3 (es) | Dispositivo para la administracion de medicamentos con liberacion controlada. | |
WO2003077972A3 (en) | Implantable drug delivery system | |
IS7155A (is) | Slímfestandi og eyðandi lyfjagjafarbúnaður til stýrðrar gjafar á lyfjum og öðrum virkum efnum | |
BR9506470B8 (pt) | Composição adesiva sensível à pressão e sistema de distribuição transdérmica de droga. | |
EE9900288A (et) | Peroraalselt manustatava farmatseutilise kompositsiooni kasutamine meeste erektiilse talitlushäire raviks ettenähtud ravimi valmistamiseks | |
DE60204075D1 (de) | Nadelloses Subkutaninjektionssystem, Anwendungsvorrichtung und Medikamentenkartusche | |
ATE285228T1 (de) | Arzneistoffverabreichungsystem zur verzögerten, völlstandigen wirkstoffabgabe im verdauungstrakt | |
PT1183061E (pt) | Sistema de administracao de medicamento | |
BRPI0508865A (pt) | dispositivo de liberação de medicamento visìvel por raio x | |
ATE94044T1 (de) | Intraorale medikamenten-freisetzungsvorrichtung. | |
FR2796287B1 (fr) | Dispositif d'administration de medicament | |
BR0014933A (pt) | Unidade e cartucho de dosagem de medicamento, dispositivo de distribuição de medicamento, e métodos de distribuição de um medicamento, de administração de um medicamento em pó seco, e, de tratamento de um paciente com um distúrbio |