ATE291417T1 - Gastrointestinales wirkstoffverabreichungssystem - Google Patents

Gastrointestinales wirkstoffverabreichungssystem

Info

Publication number
ATE291417T1
ATE291417T1 AT97900086T AT97900086T ATE291417T1 AT E291417 T1 ATE291417 T1 AT E291417T1 AT 97900086 T AT97900086 T AT 97900086T AT 97900086 T AT97900086 T AT 97900086T AT E291417 T1 ATE291417 T1 AT E291417T1
Authority
AT
Austria
Prior art keywords
delivery system
drug delivery
gastrointestinal drug
gastrointestinal
drug
Prior art date
Application number
AT97900086T
Other languages
English (en)
Inventor
E Itzhak Lerner
Moshe Flashner
Adel Penhasi
Original Assignee
Dexcel Pharma Technologies Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dexcel Pharma Technologies Ltd filed Critical Dexcel Pharma Technologies Ltd
Application granted granted Critical
Publication of ATE291417T1 publication Critical patent/ATE291417T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
AT97900086T 1996-01-18 1997-01-17 Gastrointestinales wirkstoffverabreichungssystem ATE291417T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/588,247 US5840332A (en) 1996-01-18 1996-01-18 Gastrointestinal drug delivery system
PCT/IB1997/000037 WO1997025979A1 (en) 1996-01-18 1997-01-17 Gastrointestinal drug delivery system

Publications (1)

Publication Number Publication Date
ATE291417T1 true ATE291417T1 (de) 2005-04-15

Family

ID=24353076

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97900086T ATE291417T1 (de) 1996-01-18 1997-01-17 Gastrointestinales wirkstoffverabreichungssystem

Country Status (16)

Country Link
US (1) US5840332A (de)
EP (1) EP0877604B1 (de)
JP (1) JP4165905B2 (de)
CN (1) CN1208343A (de)
AR (1) AR005451A1 (de)
AT (1) ATE291417T1 (de)
AU (1) AU713722B2 (de)
CZ (1) CZ295932B6 (de)
DE (1) DE69732830T2 (de)
ES (1) ES2241031T3 (de)
IL (1) IL125042A (de)
MY (1) MY133883A (de)
NZ (1) NZ324808A (de)
WO (1) WO1997025979A1 (de)
YU (1) YU1497A (de)
ZA (1) ZA97405B (de)

Families Citing this family (161)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU689250B2 (en) 1994-04-22 1998-03-26 Astellas Pharma Inc. Colon-specific drug release system
DK0859612T3 (da) * 1995-09-21 2003-09-22 Pharma Pass Ii Llc Farmaceutisk sammensætning indeholdende en syre-labil omeprazol og fremgangsmåde til fremstilling deraf
US6231888B1 (en) * 1996-01-18 2001-05-15 Perio Products Ltd. Local delivery of non steroidal anti inflammatory drugs (NSAIDS) to the colon as a treatment for colonic polyps
WO1998005310A1 (fr) * 1996-08-02 1998-02-12 Hisamitsu Pharmaceutical Co., Inc. Gelules destinees a des preparations orales et preparations de gelules destinees a une administration orale
SE9604751D0 (sv) * 1996-12-20 1996-12-20 Astra Ab New therapy
GB9720797D0 (en) * 1997-09-30 1997-12-03 Rhodes John Pharmaceutical composition for the treatment of inflammatory bowel disease and irritable bowel syndrome
WO1999018938A1 (en) * 1997-10-09 1999-04-22 Perio Products Ltd. Delayed total release gastrointestinal drug delivery system
US6350470B1 (en) * 1998-04-29 2002-02-26 Cima Labs Inc. Effervescent drug delivery system for oral administration
EP1079810B1 (de) * 1998-04-22 2004-06-16 Glycologic Limited Oral anwendbare zubereitungen enthaltend ein kationvernetztes polysaccharid und ein im unteren intestinalen bereich abbaubares polymer
US7022683B1 (en) 1998-05-13 2006-04-04 Carrington Laboratories, Inc. Pharmacological compositions comprising pectins having high molecular weights and low degrees of methoxylation
ES2274625T3 (es) 1998-05-18 2007-05-16 Takeda Pharmaceutical Company Limited Comprimidos desintegrables en la boca que comprenden un bencimidazol.
SI1077722T1 (sl) 1998-05-22 2007-02-28 Ottawa Health Research Inst Metode in produkti za induciranje sluznicne imunosti
AU4802099A (en) 1998-07-28 2000-02-21 Takeda Chemical Industries Ltd. Rapidly disintegrable solid preparation
AU772726B2 (en) * 1998-08-12 2004-05-06 Takeda Gmbh Oral administration form for pyridin-2-ylmethylsulfinyl-1H-benzimidazoles
US6387410B1 (en) * 1998-09-10 2002-05-14 Norton Healthcare Ltd Anti-inflammatory pharmaceutical formulations
US6514525B2 (en) 1998-09-10 2003-02-04 Norton Healthcare Ltd Anti-inflammatory pharmaceutical formulations
US6645192B2 (en) * 1998-09-30 2003-11-11 Ivy Animal Health, Inc. Pellet implant system for immediate and delayed release of antiparasitic drug
US6531152B1 (en) * 1998-09-30 2003-03-11 Dexcel Pharma Technologies Ltd. Immediate release gastrointestinal drug delivery system
US20090149479A1 (en) * 1998-11-02 2009-06-11 Elan Pharma International Limited Dosing regimen
US20060240105A1 (en) * 1998-11-02 2006-10-26 Elan Corporation, Plc Multiparticulate modified release composition
CA2348871C (en) * 1998-11-02 2009-04-14 John G. Devane Multiparticulate modified release composition
AR023700A1 (es) * 1998-11-12 2002-09-04 Smithkline Beecham Plc Un procedimiento para preparar una composicion farmaceutica que comprende un sensibilizador de insulina
SA99191255B1 (ar) 1998-11-30 2006-11-25 جي دي سيرل اند كو مركبات سيليكوكسيب celecoxib
US6432448B1 (en) * 1999-02-08 2002-08-13 Fmc Corporation Edible coating composition
US6723342B1 (en) 1999-02-08 2004-04-20 Fmc Corporation Edible coating composition
US6351665B1 (en) 1999-05-07 2002-02-26 Kenneth L Koch Method and apparatus for evaluating myoelectric signals and identifying artifact
US6632451B2 (en) * 1999-06-04 2003-10-14 Dexcel Pharma Technologies Ltd. Delayed total release two pulse gastrointestinal drug delivery system
EP1184038B1 (de) * 1999-06-09 2005-12-28 Mochida Pharmaceutical Co., Ltd. System für wirkstofffreisetzung im unteren verdauungstrakt
ATE251449T1 (de) 1999-06-14 2003-10-15 Cosmo Spa Geschmacksmaskierte orale pharmazeutische zusammensetzungen mit kontrollierter abgabe
US8895064B2 (en) 1999-06-14 2014-11-25 Cosmo Technologies Limited Controlled release and taste masking oral pharmaceutical composition
SE9902386D0 (sv) * 1999-06-22 1999-06-22 Astra Ab New formulation
US20040258750A1 (en) * 1999-06-28 2004-12-23 Gerard Alaux Timed dual release dosage forms comprising a short acting hypnotic or a salt thereof
EP1064938A1 (de) * 1999-06-28 2001-01-03 Sanofi-Synthelabo Pharmazeutische Dosierungsformen zur kontrollierte Wirkstoffabgabe mit mindenstens ein pulsierendem Zeitverlauf
KR20020015721A (ko) * 1999-08-09 2002-02-28 도모따께 다께시 키토산 분말 함유 고형 제제 및 그의 제조방법
MXPA02004293A (es) 1999-10-29 2002-10-31 Euro Celtique Sa Formulaciones de hidrocodona de liberacion controlada..
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
US6500462B1 (en) 1999-10-29 2002-12-31 Fmc Corporation Edible MCC/PGA coating composition
IL133196A0 (en) * 1999-11-29 2001-03-19 Yissum Res Dev Co Gastroretentive controlled release pharmaceutical dosage forms
US7771746B2 (en) * 1999-12-03 2010-08-10 Polichem Sa Methods for making sustained-release pharmaceutical compositions of ergot alkaloids having improved bioavailability and compositions thereof
DE19961897A1 (de) * 1999-12-20 2001-06-28 Basf Ag Verwendung eines Filmüberzuges als geschmacksmaskierendes Coating von pharmazeutischen Darreichungsformen
NZ518281A (en) * 1999-12-23 2005-01-28 Pfizer Prod Inc Controlled release drug dosage core comprising a drug-containing composition and a water-swellable composition
CA2395231C (en) 1999-12-23 2006-08-15 Pfizer Products Inc. Hydrogel-driven layered drug dosage form
US6451345B1 (en) * 2000-01-20 2002-09-17 Eurand Pharmaceuticals Ltd. Functional coating of linezolid microcapsules for taste-masking and associated formulation for oral administration
AU767812B2 (en) 2000-02-04 2003-11-27 Depomed, Inc. Shell-and-core dosage form approaching zero-order drug release
IN192159B (de) * 2000-05-15 2004-02-28 Ranbaxy Lab Ltd
CN1141974C (zh) 2000-06-07 2004-03-17 张昊 结肠定位释放的口服生物制剂
CN1285333C (zh) * 2000-06-07 2006-11-22 张昊 结肠定位释放的口服制剂及其制备方法
IL137431A0 (en) 2000-07-20 2001-07-24 Slo Flo Ltd A new slow release device for controlled delivery of liquid material
KR100411195B1 (ko) * 2000-09-26 2003-12-18 한국화학연구원 케토롤락 트로메타민이 함유된 서방형 펠렛
EP1337244A4 (de) 2000-10-30 2006-01-11 Euro Celtique Sa Hydrocodon-formulierungen mit kontrollierter freisetzung
US6932861B2 (en) * 2000-11-28 2005-08-23 Fmc Corporation Edible PGA coating composition
TR200300731T2 (tr) 2000-11-28 2004-08-23 Fmc Corporation Yenebilir PGA kaplama bileşimi
US6777000B2 (en) 2001-02-28 2004-08-17 Carrington Laboratories, Inc. In-situ gel formation of pectin
US7494669B2 (en) 2001-02-28 2009-02-24 Carrington Laboratories, Inc. Delivery of physiological agents with in-situ gels comprising anionic polysaccharides
US7316819B2 (en) * 2001-03-08 2008-01-08 Unigene Laboratories, Inc. Oral peptide pharmaceutical dosage form and method of production
AU2002313628A1 (en) * 2001-05-22 2002-12-03 Euro-Celtique Tamper resistant oral dosage form
WO2003002100A1 (en) * 2001-06-26 2003-01-09 Farrell John J Tamper-proof narcotic delivery system
US20030091630A1 (en) * 2001-10-25 2003-05-15 Jenny Louie-Helm Formulation of an erodible, gastric retentive oral dosage form using in vitro disintegration test data
CA2409552A1 (en) * 2001-10-25 2003-04-25 Depomed, Inc. Gastric retentive oral dosage form with restricted drug release in the lower gastrointestinal tract
US20030152622A1 (en) * 2001-10-25 2003-08-14 Jenny Louie-Helm Formulation of an erodible, gastric retentive oral diuretic
US20030104052A1 (en) * 2001-10-25 2003-06-05 Bret Berner Gastric retentive oral dosage form with restricted drug release in the lower gastrointestinal tract
US7045549B2 (en) 2001-11-08 2006-05-16 The Board Of Trustees Of The Leland Stanford Jr. University Treatment of symptoms associated with irritable bowel syndrome
US7550156B2 (en) 2001-11-23 2009-06-23 Rohm And Haas Company Optimised pellet formulations
MXPA04006163A (es) * 2001-12-20 2004-11-01 Pharmacia Corp Formas de dosis de liberacion sostenida del orden-cero y metodo de fabricacion de las mismas.
EP1327450B1 (de) * 2002-01-15 2007-08-15 Bio Life Science Forschungs- und Entwicklungsges.m.b.H. Orale Vakzinierung mit nackten Tumor-Antigen-Mimotopen
IL162857A0 (en) * 2002-01-15 2005-11-20 Bio Life Science Forschungs & Entwicklungsgesellschaft Mbh Oral vaccination
WO2003062199A2 (en) * 2002-01-16 2003-07-31 Agency For Disease Diagnosis And Prevention Pace-a microspheres for delivery of antigens
CN1993109A (zh) * 2002-03-05 2007-07-04 兰贝克赛实验室有限公司 释放得到改良的口服药物组合物
US20040156844A1 (en) * 2002-05-22 2004-08-12 Curtis Wright Tamper resistant oral dosage form
US6986901B2 (en) 2002-07-15 2006-01-17 Warner-Lambert Company Llc Gastrointestinal compositions
US7985422B2 (en) * 2002-08-05 2011-07-26 Torrent Pharmaceuticals Limited Dosage form
FR2843872B1 (fr) 2002-08-29 2005-08-19 C T M Ct De Transfert Des Micr Dispositif de localisation equipant une capsule intestinale
US20040062778A1 (en) * 2002-09-26 2004-04-01 Adi Shefer Surface dissolution and/or bulk erosion controlled release compositions and devices
US6703044B1 (en) * 2002-10-25 2004-03-09 Dexcel Pharma Tech, Ltd Venlafaxine formulations
JP2006507298A (ja) * 2002-10-30 2006-03-02 ファルマシア コーポレーション 経口持続放出型錠剤、ならびにその製造法および使用法
US9561182B2 (en) 2003-08-22 2017-02-07 Cure Pharmaceutical Corporation Edible films for administration of medicaments to animals, methods for their manufacture and methods for their use for the treatment of animals
CN1322865C (zh) * 2002-11-14 2007-06-27 北京东方凯恩医药科技有限公司 用于治疗菌痢的口服结肠定位给药组合物
US20040096497A1 (en) * 2002-11-19 2004-05-20 Ponder Garratt W. Methods of providing controlled-release pharmaceutical compositions and controlled-release pharmaceutical compositions
US8519008B2 (en) 2003-01-22 2013-08-27 Purina Animal Nutrition Llc Method and composition for improving the health of young monogastric mammals
US20050147663A1 (en) * 2003-07-17 2005-07-07 Mohan Mailatur S. Method of treatment for improved bioavailability
RU2375048C2 (ru) * 2003-07-17 2009-12-10 Д-Р Редди'С Лабораторис Инк. Фармацевтическая композиция с набухающим покрытием
US7825106B2 (en) 2003-09-03 2010-11-02 Agi Therapeutics Ltd. Modified release formulations and methods of treating inflammatory bowel disease
US7737133B2 (en) * 2003-09-03 2010-06-15 Agi Therapeutics Ltd. Formulations and methods of treating inflammatory bowel disease
KR100782918B1 (ko) * 2003-09-19 2007-12-07 펜웨스트 파머슈티칼즈 컴파니 지연 방출성 제형
EP1682537B1 (de) 2003-11-05 2012-03-28 SARcode Bioscience Inc. Modulatoren der zellulären adhäsion
US20050175695A1 (en) * 2003-11-25 2005-08-11 Catherine Castan Carvedilol free base, salts, anhydrous forms or solvates thereof, corresponding pharmaceutical compositions, controlled release formulations, and treatment or delivery methods
EP1718148A2 (de) * 2004-02-03 2006-11-08 The Regents of the University of California Verfahren zur behandlung von reizdarmsyndrom
CA2568542A1 (en) * 2004-05-27 2005-12-08 Dexcel Pharma Technologies Ltd. Localized controlled absorption of statins in the gastrointestinal tract for achieving high blood levels of statins
WO2006054307A2 (en) * 2004-11-22 2006-05-26 Dexcel Pharma Technologies Ltd. Controlled absorption of statins in the intestine
CA2588216A1 (en) * 2004-11-22 2006-05-26 Dexcel Pharma Technologies Ltd. Stable atorvastatin formulations
FR2878159B1 (fr) * 2004-11-24 2008-10-17 Flamel Technologies Sa Medicament oral a liberation modifiee d'au moins un principe actif sous forme multimicrocapsulaire
US20060121112A1 (en) * 2004-12-08 2006-06-08 Elan Corporation, Plc Topiramate pharmaceutical composition
JP2008525313A (ja) 2004-12-27 2008-07-17 エーザイ・アール・アンド・ディー・マネジメント株式会社 抗痴呆薬の安定化方法
US20060159753A1 (en) * 2004-12-27 2006-07-20 Eisai Co. Ltd. Matrix type sustained-release preparation containing basic drug or salt thereof
EP1846042A2 (de) * 2005-01-05 2007-10-24 Board of Regents, The University of Texas System Konjugate zur doppelten abbildung und radiochemotherapie: zusammensetzung sowie herstellung und anwendungen davon
SI1698630T1 (sl) 2005-03-03 2015-01-30 Alfa Wassermann S.P.A. Nove polimorfne oblike rifaksimina, postopki za njihovo pripravo in njihova uporaba v medicinskih pripravkih
ITBO20050123A1 (it) * 2005-03-07 2005-06-06 Alfa Wassermann Spa Formulazioni farmaceutiche gastroresistenti contenenti rifaximina
CA2601800C (en) * 2005-03-14 2013-12-03 Nitin Bhalachandra Dharmadhikari Oral drug delivery system
WO2006103661A2 (en) * 2005-03-28 2006-10-05 Dexcel Pharma Technologies Ltd. Controlled absorption of statins in the intestine
KR20080007586A (ko) * 2005-04-12 2008-01-22 엘란 파마 인터내셔널 리미티드 세균감염증의 치료를 위한 세팔로스포린 함유 조절 방출조성물
ES2614080T3 (es) * 2005-05-17 2017-05-29 Sarcode Bioscience Inc. Composiciones y métodos para el tratamiento de trastornos oculares
US20060280795A1 (en) 2005-06-08 2006-12-14 Dexcel Pharma Technologies, Ltd. Specific time-delayed burst profile delivery system
US8778395B2 (en) * 2005-08-11 2014-07-15 Andrx Labs, Llc Diltiazem controlled release formulation and method of manufacture
US20070082029A1 (en) * 2005-10-07 2007-04-12 Aimutis William R Fiber satiety compositions
US20070082027A1 (en) * 2005-10-07 2007-04-12 Aimutis William R Jr Compositions and methods for reducing food intake and controlling weight
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
CA2656411A1 (en) 2006-06-28 2008-01-03 Surmodics, Inc. Combination degradable and non-degradable matrices for active agent delivery
MY149863A (en) 2006-08-03 2013-10-31 Nitec Pharma Ag Delayed-release glucocorticoid treatment of rheumatoid disease
US8889184B2 (en) * 2006-09-07 2014-11-18 Losan Pharma Gmbh Particulate form of a pharmaceutical composition which is easy to swallow
EP2079448A2 (de) * 2006-10-10 2009-07-22 Dexcel Pharma Technologies Ltd. Verbesserte freisetzung von statinen im darm
EP2081557A1 (de) * 2006-11-17 2009-07-29 DA Volterra Abgabe im kolon mit zn/pectin-perlen mit eudragit-beschichtung
US8273376B2 (en) 2006-11-17 2012-09-25 Da Volterra Colonic delivery of metallo-dependent enzymes
US20080260823A1 (en) * 2007-04-20 2008-10-23 Sciele Pharma, Inc. Orally disintegrating tablet comprising glycopyrrolate for treating sialorrhea
US20090036414A1 (en) * 2007-08-02 2009-02-05 Mutual Pharmaceutical Company, Inc. Mesalamine Formulations
US20100239682A1 (en) * 2007-09-17 2010-09-23 Antoine Andremont Colonic delivery of antimicrobial agents
EP3797775A1 (de) 2007-10-19 2021-03-31 Novartis AG Zusammensetzungen und verfahren zur behandlung von diabetischer retinopathie
US8865692B2 (en) 2007-11-13 2014-10-21 Meritage Pharma, Inc Compositions for the treatment of gastrointestinal inflammation
US20100216754A1 (en) * 2007-11-13 2010-08-26 Meritage Pharma, Inc. Compositions for the treatment of inflammation of the gastrointestinal tract
EP3574914B1 (de) 2007-11-13 2021-12-29 ViroPharma Biologics LLC Kortikosteroidzusammensetzungen
US20090169622A1 (en) * 2007-12-27 2009-07-02 Roxane Laboratories, Inc. Delayed-release oral pharmaceutical composition for treatment of colonic disorders
WO2009139817A2 (en) 2008-04-15 2009-11-19 Sarcode Corporation Crystalline pharmaceutical and methods of preparation and use thereof
ES2425762T3 (es) * 2008-10-27 2013-10-17 Roquette Freres Polímero insoluble en agua: revestimientos de película a base de derivados de almidón modificado para la liberación dirigida al colon
NZ582836A (en) * 2009-01-30 2011-06-30 Nitec Pharma Ag Delayed-release glucocorticoid treatment of rheumatoid arthritis by improving signs and symptoms, showing major or complete clinical response and by preventing from joint damage
US8945616B2 (en) * 2009-02-17 2015-02-03 Mylan Pharmaceuticals Inc. Controlled release budesonide minitablets
US8945615B2 (en) * 2009-02-17 2015-02-03 Mylan Pharmaceuticals Inc. Controlled release budesonide minitablets
CA2754604A1 (en) * 2009-03-13 2010-09-16 Da Volterra Compositions and methods for elimination of gram-negative bacteria
EP2440210A4 (de) * 2009-06-12 2014-01-29 Meritage Pharma Inc Verfahren zur behandlung von magen-darm-erkrankungen
WO2011050175A1 (en) 2009-10-21 2011-04-28 Sarcode Corporation Crystalline pharmaceutical and methods of preparation and use thereof
IT1398550B1 (it) 2010-03-05 2013-03-01 Alfa Wassermann Spa Formulazioni comprendenti rifaximina utili per ottenere un effetto prolungato nel tempo
WO2011160062A2 (en) 2010-06-17 2011-12-22 The Usa As Represented By The Secretary, National Institutes Of Health Compositions and methods for treating inflammatory conditions
US8911780B2 (en) 2011-02-11 2014-12-16 Zx Pharma, Llc Multiparticulate L-menthol formulations and related methods
US8808736B2 (en) 2011-02-11 2014-08-19 Zx Pharma, Llc Enteric coated multiparticulate controlled release peppermint oil composition and related methods
CN103442727B (zh) 2011-02-11 2016-08-10 Zx制药有限责任公司 多微粒l-薄荷醇制剂及相关方法
BR112013029199B1 (pt) 2011-05-13 2022-02-08 Eb Ip Hybritabs B.V. Dispositivo de distribuição de dois fármacos
ITBO20110461A1 (it) 2011-07-29 2013-01-30 Alfa Wassermann Spa Composizioni farmaceutiche comprendenti rifaximina, processi per la loro preparazione e loro uso nel trattamento di infezioni vaginali.
US10154964B2 (en) 2011-09-07 2018-12-18 Cosmo Technologies Limited Controlled release and taste masking oral pharmaceutical composition
ITBO20120368A1 (it) 2012-07-06 2014-01-07 Alfa Wassermann Spa Composizioni comprendenti rifaximina e amminoacidi, cristalli di rifaximina derivanti da tali composizioni e loro uso.
CN104797574B (zh) 2012-07-25 2019-11-22 原生质生物科学股份有限公司 Lfa-1抑制剂及其多晶型物
US20140066837A1 (en) 2012-07-26 2014-03-06 Ronald L. Moy Skin care compositions and methods
US9289418B2 (en) 2013-03-15 2016-03-22 Cedars-Sinai Medical Center Methods of diagnosis, selection, and treatment of diseases and conditions caused by or associated with methanogens
EP2967060A4 (de) 2013-03-15 2016-11-23 Cedars Sinai Medical Center Verfahren zur diagnose, auswahl und behandlung von erkrankungen und zuständen durch oder in zusammenhang mit methanogenen
EP2978416B1 (de) * 2013-03-26 2016-10-26 Lipid Therapeutics GmbH Pharmazeutische formulierung mit phosphatidylcholin zur behandlung von colitis ulcerosa
RS58325B1 (sr) 2013-04-23 2019-03-29 Zx Pharma Llc Enterosolventno obloženi višečestični preparat sa proteinskom sub-oblogom
PL3546464T3 (pl) 2014-05-12 2020-11-02 Alfasigma S.P.A. Sposób wytwarzania i zastosowanie postaci krystalicznej Tau rifaksyminy solwatowanej z DEGME
BR112016028957B1 (pt) 2014-06-11 2021-12-14 The Brigham And Women's Hospital, Inc. Estrutura de residência gástrica
US20170266112A1 (en) 2014-06-11 2017-09-21 Massachusetts Institute Of Technology Residence structures and related methods
EP3179983A4 (de) 2014-08-13 2018-01-10 Cedars-Sinai Medical Center Anti-methanogene zusammensetzungen und verwendungen davon
US20160158174A1 (en) * 2014-12-09 2016-06-09 Intercontinental Great Brands Llc Enteric-Coated Functional Food Ingredients And Methods For Making The Enteric-Coated Functional Food Ingredients
US10736871B2 (en) 2015-04-01 2020-08-11 Cedars-Sinai Medical Center Anti-methanogenic lovastatin analogs or derivatives and uses thereof
CA2983272C (en) 2015-05-01 2023-08-29 Massachusetts Institute Of Technology Triggerable shape memory induction devices
WO2017070612A1 (en) 2015-10-23 2017-04-27 Lyndra, Inc. Gastric residence systems for sustained release of therapeutic agents and methods of use thereof
CN108697649A (zh) 2015-12-08 2018-10-23 林德拉有限公司 用于胃驻留系统的几何构型
RU2745992C2 (ru) * 2016-04-25 2021-04-05 Джелесис ЭлЭлСи Способ лечения запора
CN117482062A (zh) 2016-05-06 2024-02-02 雀巢产品有限公司 缬草组合物和相关方法
JP6780412B2 (ja) * 2016-09-28 2020-11-04 ライオン株式会社 コーティング組成物ならびにコーティング製剤及びその製造方法
CN110022861A (zh) 2016-09-30 2019-07-16 林德拉有限公司 用于金刚烷类药物缓释的胃驻留系统
US10940113B2 (en) * 2017-02-24 2021-03-09 Medical And Pharmaceutical Industry Technology And Development Center Pharmaceutical composition for colon targeting, method for treating a colon-related disease using the same and preparation method thereof
AU2018279853A1 (en) * 2017-06-09 2020-01-02 Lyndra Therapeutics, Inc. Gastric residence systems with release rate-modulating films
WO2019217601A1 (en) * 2018-05-08 2019-11-14 Protz Jonathan M Methods and compositions for drug targeted delivery
US11826437B2 (en) * 2020-10-19 2023-11-28 The Procter & Gamble Company Oral care article comprising a hydrophobic delivery carrier and solid hydrophilic particle comprising a bleaching agent
CN114224860B (zh) * 2021-11-06 2023-04-28 山东润德生物科技有限公司 氨基葡萄糖钙片制剂及其制备方法与应用

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3845770A (en) * 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
US3921636A (en) * 1973-01-15 1975-11-25 Alza Corp Novel drug delivery device
US3916899A (en) * 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway
SE7504049L (sv) * 1975-04-09 1976-10-10 Haessle Ab Colonpreparation
DE2717707C3 (de) * 1977-04-21 1979-11-22 Chephasaar Chemisch-Pharmazeutische Fabrik Gmbh, 6670 St Ingbert Karamellisierte Lactulose
US4327725A (en) * 1980-11-25 1982-05-04 Alza Corporation Osmotic device with hydrogel driving member
JPS57197214A (en) * 1981-05-29 1982-12-03 Tanabe Seiyaku Co Ltd Rapid-releasing microcapsule and its preparation
JPS5858145A (ja) * 1981-10-05 1983-04-06 Tanabe Seiyaku Co Ltd 速放性マイクロカプセル
JPS5867616A (ja) * 1981-10-15 1983-04-22 Tanabe Seiyaku Co Ltd 腸溶性マイクロカプセル
JPS59193831A (ja) * 1983-04-18 1984-11-02 Sankyo Co Ltd 腸溶性製剤の製造法
US4503030A (en) * 1983-06-06 1985-03-05 Alza Corporation Device for delivering drug to certain pH environments
US4627850A (en) * 1983-11-02 1986-12-09 Alza Corporation Osmotic capsule
US4863744A (en) * 1984-09-17 1989-09-05 Alza Corporation Intestine drug delivery
US4610870A (en) * 1984-10-05 1986-09-09 E. R. Squibb & Sons, Inc. Controlled release formulation
US4668517A (en) * 1985-04-04 1987-05-26 Norwich Eaton Pharmaceuticals, Inc. Furazolidone dosage form
GB8518301D0 (en) * 1985-07-19 1985-08-29 Fujisawa Pharmaceutical Co Hydrodynamically explosive systems
EP0250374B1 (de) * 1986-06-17 1991-05-02 RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA S.p.a. Therapeutisches System mit geregelter Wirkstoffabgabe
CA1316110C (en) * 1987-02-27 1993-04-13 Peter Lloyd Oren Sustained release matrix formulations
GB8705083D0 (en) * 1987-03-04 1987-04-08 Euro Celtique Sa Spheroids
US4904474A (en) * 1988-01-25 1990-02-27 Alza Corporation Delivery of drug to colon by oral disage form
DK110188D0 (da) * 1988-03-02 1988-03-02 Claus Selch Larsen High molecular weight prodrug derivatives of antiinflammatory drugs
US4857331A (en) * 1988-03-31 1989-08-15 Warner-Lambert Company Sugarless pectin delivery system
IT1219942B (it) * 1988-05-13 1990-05-24 Fidia Farmaceutici Esteri polisaccaridici
IT1219587B (it) * 1988-05-13 1990-05-18 Fidia Farmaceutici Polisaccaridi carbossiilici autoreticolati
US4925677A (en) * 1988-08-31 1990-05-15 Theratech, Inc. Biodegradable hydrogel matrices for the controlled release of pharmacologically active agents
US5133974A (en) * 1989-05-05 1992-07-28 Kv Pharmaceutical Company Extended release pharmaceutical formulations
US4983401A (en) * 1989-05-22 1991-01-08 Kinaform Technology, Inc. Sustained release pharmaceutical preparations having pH controlled membrane coatings
GB8926639D0 (en) * 1989-11-24 1990-01-17 Agricultural & Food Res Delayed release formulations
DE4006521A1 (de) * 1990-03-02 1991-09-05 Bayer Ag Zuckerhaltige polymere zur umhuellung und einbettung von arzneistoffen
IT1246382B (it) * 1990-04-17 1994-11-18 Eurand Int Metodo per la cessione mirata e controllata di farmaci nell'intestino e particolarmente nel colon
SE9002339L (sv) * 1990-07-04 1992-01-05 Kabi Pharmacia Ab Terapeutisk komposition och foerfarande foer dess framstaellning
DE9015551U1 (de) * 1990-11-14 1992-03-12 Roehm Gmbh, 6100 Darmstadt, De
US5422121A (en) * 1990-11-14 1995-06-06 Rohm Gmbh Oral dosage unit form
NZ286242A (en) * 1991-03-26 1997-11-24 Csl Ltd Use of veterinary implant as a single dose vaccination system: rupturable polymer film coating around core of active agent and water soluble excipient
DE4200821A1 (de) * 1992-01-15 1993-07-22 Bayer Ag Geschmacksmaskierte pharmazeutische mittel
DE4236025A1 (de) * 1992-10-24 1994-04-28 Merck Patent Gmbh Orale Arzneiformen
FR2698560B1 (fr) * 1992-11-30 1995-02-03 Virbac Laboratoires Principes actifs pulvérulents stabilisés, compositions les contenant, leur procédé d'obtention et leurs applications.
DE4318375A1 (de) * 1993-05-28 1994-12-01 Rottendorf Pharma Gmbh Mischung zur Schaffung von Filmüberzügen für Tabletten od. dgl.
FR2723536A1 (fr) * 1994-08-11 1996-02-16 Seth Pawan Composition permettant une liberation selective d'un principe actif

Also Published As

Publication number Publication date
DE69732830T2 (de) 2006-04-13
ES2241031T3 (es) 2005-10-16
YU1497A (sh) 1999-09-27
AU713722B2 (en) 1999-12-09
CZ295932B6 (cs) 2005-12-14
AU1206597A (en) 1997-08-11
ZA97405B (en) 1997-07-30
IL125042A0 (en) 1999-01-26
EP0877604B1 (de) 2005-03-23
WO1997025979A1 (en) 1997-07-24
JP4165905B2 (ja) 2008-10-15
IL125042A (en) 2005-03-20
US5840332A (en) 1998-11-24
NZ324808A (en) 1999-10-28
JP2000503316A (ja) 2000-03-21
MY133883A (en) 2007-11-30
CZ219898A3 (cs) 1998-12-16
CN1208343A (zh) 1999-02-17
DE69732830D1 (de) 2005-04-28
AR005451A1 (es) 1999-06-23
EP0877604A1 (de) 1998-11-18

Similar Documents

Publication Publication Date Title
ATE291417T1 (de) Gastrointestinales wirkstoffverabreichungssystem
NO994837L (no) Intravesikal medikamentavleveringssystem
BR9801027B1 (pt) sistema de distribuiÇço de medicamentos.
DE69822529D1 (de) Stentanbringungssystem
DE69531788D1 (de) Verbessertes bioadhäsives pharmazeutisches abgabesystem
DE69730666D1 (de) Stentanbringungssystem
DE69731915D1 (de) Stentanbringungssystem
DE69832055D1 (de) Transdermales abgabesystem
ID23874A (id) Obat
GB2319184B (en) Drug delivery device
DE69711045D1 (de) Vitamin c abgabesystem
EE200000546A (et) Aerosoolistatud toimeaine manustamissüsteem
EE9800025A (et) Transkorneaalne süsteem ravimite manustamiseks
DE59701787D1 (de) Medikamenten-dosiersystem
DE69638138D1 (de) S endoluminarspiral-abgabesystem
NO20004196D0 (no) Innretninger for legemiddelavlevering
EP1061987A4 (de) Vorrichtung zum verabreichen eines medikamentes
EP0989878A4 (de) Arzneimittelverabreichungssystem
DE1003485T1 (de) Mikroosmotisches gesteuertes arzneistoffabgabesysteme
EP1021137A4 (de) Anordnung zur medikamentenzuführung
GB9714750D0 (en) Drug delivery device
EP0913159A4 (de) Arzneistoffverabreichungssystem unter verwendung von galactoxyloglucan
DE69740133D1 (de) Patiententransportsystem
GB9600471D0 (en) Drug delivery system
DK1183061T3 (da) Lægemiddelafgivelsessystem

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties