ZA817477B - Vaginal ring - Google Patents

Vaginal ring

Info

Publication number
ZA817477B
ZA817477B ZA817477A ZA817477A ZA817477B ZA 817477 B ZA817477 B ZA 817477B ZA 817477 A ZA817477 A ZA 817477A ZA 817477 A ZA817477 A ZA 817477A ZA 817477 B ZA817477 B ZA 817477B
Authority
ZA
South Africa
Prior art keywords
layer
active agent
free
vaginal ring
supporting ring
Prior art date
Application number
ZA817477A
Other languages
English (en)
Inventor
Infried Zimmermann
Fred Windt
Hans Juergen Reck
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of ZA817477B publication Critical patent/ZA817477B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F6/00—Contraceptive devices; Pessaries; Applicators therefor
    • A61F6/06—Contraceptive devices; Pessaries; Applicators therefor for use by females
    • A61F6/08—Pessaries, i.e. devices worn in the vagina to support the uterus, remedy a malposition or prevent conception, e.g. combined with devices protecting against contagion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time

Landscapes

  • Health & Medical Sciences (AREA)
  • Reproductive Health (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Anesthesiology (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Absorbent Articles And Supports Therefor (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • General Induction Heating (AREA)
  • Control And Safety Of Cranes (AREA)
ZA817477A 1980-10-28 1981-10-28 Vaginal ring ZA817477B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803040978 DE3040978A1 (de) 1980-10-28 1980-10-28 Vaginalring

Publications (1)

Publication Number Publication Date
ZA817477B true ZA817477B (en) 1982-10-27

Family

ID=6115593

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA817477A ZA817477B (en) 1980-10-28 1981-10-28 Vaginal ring

Country Status (26)

Country Link
US (1) US4822616A (sv)
EP (1) EP0050867B1 (sv)
JP (2) JPS5799954A (sv)
AT (1) ATE31875T1 (sv)
AU (1) AU7670981A (sv)
BG (1) BG42182A3 (sv)
CA (1) CA1165239A (sv)
CS (1) CS253564B2 (sv)
DD (1) DD201645A5 (sv)
DE (2) DE3040978A1 (sv)
DK (1) DK151529C (sv)
EG (1) EG15347A (sv)
ES (2) ES527301A0 (sv)
FI (1) FI78389C (sv)
GR (1) GR75367B (sv)
HU (1) HU183646B (sv)
IE (1) IE54581B1 (sv)
IL (1) IL64139A (sv)
NO (1) NO153753C (sv)
PL (1) PL127941B1 (sv)
PT (1) PT73886B (sv)
RO (1) RO88674A (sv)
SU (1) SU1440326A3 (sv)
YU (1) YU252281A (sv)
ZA (1) ZA817477B (sv)
ZW (1) ZW26081A1 (sv)

Families Citing this family (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3347125A1 (de) * 1983-12-22 1985-07-11 Schering AG, 1000 Berlin und 4709 Bergkamen Mehrstufenkombinationspraeparat und seine verwendung zur oralen kontrazeption
GB8430703D0 (en) * 1984-12-05 1985-01-16 Lrc Products Drug release devices
FR2618329B1 (fr) * 1987-07-22 1997-03-28 Dow Corning Sa Procede de fabrication d'un anneau capable d'assurer la liberation d'un agent therapeutique, et anneau fabrique par ce procede
US5295984A (en) 1989-12-07 1994-03-22 Ultrafem, Inc. Vaginal discharge collection device and intravaginal drug delivery system
US6264638B1 (en) * 1989-12-07 2001-07-24 Ultrafem, Inc. Intravaginal drug delivery system and discharge collection device
WO1992018101A1 (en) * 1991-04-12 1992-10-29 The Upjohn Company Vaginal drug delivery device
FI95768C (sv) * 1993-06-17 1996-03-25 Leiras Oy Intravaginalt doseringssystem
GB9326255D0 (en) * 1993-12-23 1994-02-23 Roussel Lab Ltd Medical device for the prevention and treatment of cancer
AU6360896A (en) * 1995-07-04 1997-02-05 Akzo Nobel N.V. Ring-shaped devices
GB9522403D0 (en) * 1995-11-01 1996-01-03 Hoechst Roussel Ltd Intravaginal drug delivery device
US5816248A (en) * 1996-03-29 1998-10-06 Iotek, Inc. Channeled vaginal insert and method for treating urogenital disorders
US5988169A (en) * 1996-03-29 1999-11-23 Iotek, Inc. Vaginal insert and method for treating urogenital disorders
US6030375A (en) * 1996-03-29 2000-02-29 Iotek, Inc. Compressible vaginal insert and method for treating urogenital disorders
WO1998000184A1 (en) 1996-07-03 1998-01-08 Ultrafem, Inc. Method and system for manufacturing elastomeric articles
US5972372A (en) * 1996-07-31 1999-10-26 The Population Council, Inc. Intravaginal rings with insertable drug-containing core
TW358031B (en) * 1997-04-11 1999-05-11 Akze Nobel N V Drug delivery system for 2 or more active substances
US6039968A (en) * 1997-06-24 2000-03-21 Hoechst Marion Roussel Intravaginal drug delivery device
JP2002513690A (ja) 1998-05-01 2002-05-14 エフイ−アイ エンタープライジズ，リミティド 制御放出デバイスの射出成形製造方法
EP1313422B1 (en) 2000-08-24 2010-01-20 Sidney Lerner Non-hormonal vaginal contraceptive
DE60116520T2 (de) * 2000-10-10 2006-08-31 Microchips, Inc., Bedford Microchip-reservoir-vorrichtungen mit drahtloser übertragung von energie und daten
RU2302883C2 (ru) * 2001-08-31 2007-07-20 Шеринг Ой Система доставки лекарств
US7497855B2 (en) * 2002-09-04 2009-03-03 Microchips, Inc. Method and device for the controlled delivery of parathyroid hormone
US7357046B2 (en) 2002-12-16 2008-04-15 N. V. Organon Method for dissolution testing of a pharmaceutical delivery device
ATE461681T1 (de) * 2003-04-29 2010-04-15 Gen Hospital Corp Verfahren und vorrichtungen für die verzögerte freisetzung von mehreren arzneimitteln
TWI336627B (en) 2003-05-23 2011-02-01 Organon Nv Drug delivery system,and use and manufacturing method thereof
JP2007530500A (ja) 2004-03-24 2007-11-01 ナームローゼ・フエンノートチヤツプ・オルガノン ポリエチレン酢酸ビニル共重合体に基づく薬物送達システム
US7488316B2 (en) * 2005-01-25 2009-02-10 Microchips, Inc. Control of drug release by transient modification of local microenvironments
US20080076975A1 (en) * 2005-01-25 2008-03-27 Microchips, Inc. Method and implantable device with reservoir array for pre-clinical in vivo testing
CN1899643B (zh) * 2005-07-20 2010-12-29 上海市计划生育科学研究所 含有抗雌激素和抗孕激素复合制剂的阴道环或宫内释药装置及其制药用途
US8399012B2 (en) * 2006-04-17 2013-03-19 Kimberly-Clark Worldwide, Inc. Degradable therapeutic delivery device
AR066166A1 (es) 2007-09-21 2009-07-29 Organon Nv Sistema de suministro de droga
TW200927141A (en) * 2007-11-22 2009-07-01 Bayer Schering Pharma Oy Vaginal delivery system
ES2645630T3 (es) 2008-02-04 2017-12-07 Ferring B.V. Anillos intravaginales monolíticos que comprenden progesterona y métodos de fabricación y usos de los mismos
US20100040671A1 (en) * 2008-08-12 2010-02-18 Ahmed Salah U Intravaginal Devices With a Rigid Support, Methods of Making, and Uses Thereof
US8419793B2 (en) * 2008-09-19 2013-04-16 Mentor Worldwide Llc Coating with antimicrobial agents
US8420153B2 (en) * 2008-09-19 2013-04-16 Mentor Worldwide Llc Coating with antimicrobial agents
EP4108216A1 (en) 2009-06-03 2022-12-28 Forsight Vision5, Inc. Anterior segment drug delivery
CA2767967C (en) 2009-07-21 2014-10-21 The Population Council, Inc. Multi-layered gradient vaginal ring
MX2012012695A (es) 2010-05-05 2013-02-26 Teva Womens Health Inc Metodos para reducir sintomas en sujetos utilizando formas de dosificacion individuales con velocidades de liberacion que disminuyen gradualmente.
US8580294B2 (en) 2010-10-19 2013-11-12 International Partnership For Microbicides Platinum-catalyzed intravaginal rings
DE202012012713U1 (de) 2011-03-04 2014-01-23 Arstat, Inc. Intravaginale Arzneimittelabgabevorrichtung
DE202011110355U1 (de) 2011-03-09 2014-01-15 Arstat, Inc. Behandlung von Uterusmyomen durch intravaginale Verabreichung einer niedrigen Dosis eines selektiven Progesteronrezeptormodulators, eines Antigestagens oder eines Antigestagen-Wirkstoffes
WO2012121778A1 (en) 2011-03-10 2012-09-13 Arstat, Inc. Treatment of endometriosis by intravaginal administration of selective progesterone receptor modulator (sprm), anti-progestin, or anti-progestational agent
WO2012138542A1 (en) * 2011-04-07 2012-10-11 Arstat, Inc. Treatment of menstrual pain and excessive menstrual blood loss by intravaginal administration of a low dose of antifibrinolytic or hemostatic agent in combination with non- steroidal anti-inflammatory drug
WO2012170578A1 (en) * 2011-06-06 2012-12-13 Oak Crest Institute Of Science Drug delivery device employing wicking release window
CN103917202B (zh) 2011-09-14 2016-06-29 弗赛特影像5股份有限公司 眼插入件装置和方法
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
PT2782584T (pt) 2011-11-23 2021-09-02 Therapeuticsmd Inc Preparações e terapias de substituição para hormonoterapias naturais combinadas
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
JP6298068B2 (ja) 2012-10-26 2018-03-20 フォーサイト・ビジョン５・インコーポレイテッドＦｏｒｓｉｇｈｔ Ｖｉｓｉｏｎ５，Ｉｎｃ． 眼に対する薬物徐放用眼科システム
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
WO2015055789A1 (en) 2013-10-17 2015-04-23 Bayer Pharma Aktiengesellschaft INTRAVAGINAL USE OF 18-METHYL-15ß,16ß-METHYLENE-19-NOR-20-SPIROX-4-EN-3-ONES, INTRAVAGINAL RINGS COMPRISING 18-METHYL-15ß,16ß-METHYLENE-19-NOR-20-SPIROX-4-EN-3-ONES, AND USE THEREOF IN CONTRACEPTION
US10137031B2 (en) 2013-11-14 2018-11-27 International Partnership For Microbicides, Inc. Combination therapy intravaginal rings
US10413504B2 (en) 2013-12-11 2019-09-17 Merck Sharp & Dohme Corp. Intravaginal ring drug delivery system
WO2015086489A1 (en) 2013-12-11 2015-06-18 Merck Sharp & Dohme B.V. Drug delivery system for delivery of anti-virals
DE102014004388A1 (de) * 2014-03-26 2015-10-01 Angela Kayser Verfahren und System zum intravaginalen Verabreichen von Progesteron
JP2017516768A (ja) 2014-05-22 2017-06-22 セラピューティックスエムディー インコーポレーテッドＴｈｅｒａｐｅｕｔｉｃｓｍｄ， Ｉｎｃ． 天然の併用ホルモン補充療法剤及び療法
EP3283004A4 (en) 2015-04-13 2018-12-05 Forsight Vision5, Inc. Ocular insert composition of semi-crystalline or crystalline pharmaceutically active agent
EP3294300A1 (en) 2015-05-13 2018-03-21 Bayer Oy A long acting drug delivery device and its use in contraception
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
EP3432889B1 (en) * 2016-03-23 2022-08-10 The University of North Carolina at Chapel Hill Geometrically complex intravaginal rings, systems and methods of making the same
KR20180126582A (ko) 2016-04-01 2018-11-27 쎄러퓨틱스엠디, 인코퍼레이티드 스테로이드 호르몬 약제학적 조성물
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
WO2018202574A1 (en) 2017-05-04 2018-11-08 Bayer Oy Intravaginal drug delivery system, method for manufacturing such system and its use in gynecological therapies and contraception
DE102017113166A1 (de) 2017-06-14 2018-12-20 Amw Gmbh Depotform zur Abgabe eines Östrogen-Wirkstoffs
CN111801072A (zh) 2017-10-27 2020-10-20 锐诺维公司 用于训练盆底肌的装置、系统和方法
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3279996A (en) * 1962-08-28 1966-10-18 Jr David M Long Polysiloxane carrier for controlled release of drugs and other agents
US3545439A (en) * 1968-01-04 1970-12-08 Upjohn Co Medicated devices and methods
US3854480A (en) * 1969-04-01 1974-12-17 Alza Corp Drug-delivery system
CA988849A (en) * 1969-06-16 1976-05-11 Antonio Scommegna Anti-fertility device
GB1264731A (sv) * 1969-11-10 1972-02-23
US3845761A (en) * 1970-06-02 1974-11-05 Alza Corp Intrauterine contraceptive anti-fertility device for the management of reproduction
US3920805A (en) * 1971-12-09 1975-11-18 Upjohn Co Pharmaceutical devices and method
US3851648A (en) * 1973-10-11 1974-12-03 Mead Johnson & Co Zero-order release device
FR2270899A1 (en) * 1974-05-16 1975-12-12 Groves Harvey Vaginal medicator with long medicament-carrying stem - having anchor to correctly position stem
DE2445971A1 (de) * 1974-09-24 1976-04-08 Schering Ag Arzneimittelwirkstofftraeger ii
IL48277A (en) * 1974-10-18 1978-03-10 Schering Ag Vaginal ring
US4155991A (en) * 1974-10-18 1979-05-22 Schering Aktiengesellschaft Vaginal ring
DE2450107A1 (de) * 1974-10-18 1976-04-29 Schering Ag Vaginalring
US4215691A (en) * 1978-10-11 1980-08-05 Alza Corporation Vaginal contraceptive system made from block copolymer
US4292965A (en) * 1978-12-29 1981-10-06 The Population Council, Inc. Intravaginal ring

Also Published As

Publication number Publication date
CS253564B2 (en) 1987-11-12
FI78389B (fi) 1989-04-28
IL64139A (en) 1985-07-31
EG15347A (en) 1986-03-31
PT73886A (fr) 1981-11-01
PT73886B (fr) 1983-01-25
CA1165239A (en) 1984-04-10
JPH048893Y2 (sv) 1992-03-05
DK151529B (da) 1987-12-14
NO813625L (no) 1982-04-29
ES8505538A1 (es) 1985-06-16
BG42182A3 (en) 1987-10-15
SU1440326A3 (ru) 1988-11-23
IE812503L (en) 1982-04-28
JPH0324119U (sv) 1991-03-13
JPS5799954A (en) 1982-06-21
HU183646B (en) 1984-05-28
YU252281A (en) 1984-04-30
NO153753B (no) 1986-02-10
DK151529C (da) 1988-05-30
NO153753C (no) 1986-05-21
FI813360L (fi) 1982-04-29
DE3176606D1 (en) 1988-02-18
DD201645A5 (de) 1983-08-03
ZW26081A1 (en) 1982-05-19
PL127941B1 (en) 1983-12-31
IL64139A0 (en) 1982-01-31
DE3040978A1 (de) 1982-05-27
AU7670981A (en) 1982-05-06
PL233606A1 (sv) 1982-06-21
ES261058U (es) 1982-05-01
US4822616A (en) 1989-04-18
FI78389C (sv) 1989-08-10
IE54581B1 (en) 1989-12-06
ATE31875T1 (de) 1988-01-15
GR75367B (sv) 1984-07-13
ES527301A0 (es) 1985-06-16
EP0050867A1 (en) 1982-05-05
RO88674A (ro) 1986-06-30
DK471481A (da) 1982-04-29
EP0050867B1 (en) 1988-01-13

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