ZA201007589B - Antioxidant inflammation modulators: c-17 homologated oleanolic acid derivatives - Google Patents
Antioxidant inflammation modulators: c-17 homologated oleanolic acid derivativesInfo
- Publication number
- ZA201007589B ZA201007589B ZA2010/07589A ZA201007589A ZA201007589B ZA 201007589 B ZA201007589 B ZA 201007589B ZA 2010/07589 A ZA2010/07589 A ZA 2010/07589A ZA 201007589 A ZA201007589 A ZA 201007589A ZA 201007589 B ZA201007589 B ZA 201007589B
- Authority
- ZA
- South Africa
- Prior art keywords
- acid derivatives
- oleanolic acid
- antioxidant inflammation
- inflammation modulators
- homologated oleanolic
- Prior art date
Links
- MIJYXULNPSFWEK-GTOFXWBISA-N 3beta-hydroxyolean-12-en-28-oic acid Chemical class C1C[C@H](O)C(C)(C)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C(O)=O)CCC(C)(C)C[C@H]5C4=CC[C@@H]3[C@]21C MIJYXULNPSFWEK-GTOFXWBISA-N 0.000 title 1
- 206010061218 Inflammation Diseases 0.000 title 1
- 239000003963 antioxidant agent Substances 0.000 title 1
- 230000003078 antioxidant effect Effects 0.000 title 1
- 230000004054 inflammatory process Effects 0.000 title 1
Classifications
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- C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
- C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
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- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/45—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C255/47—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of rings being part of condensed ring systems
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4636608P | 2008-04-18 | 2008-04-18 | |
| US11129408P | 2008-11-04 | 2008-11-04 | |
| PCT/US2009/041176 WO2009129548A1 (en) | 2008-04-18 | 2009-04-20 | Antioxidant inflammation modulators: c-17 homologated oleanolic acid derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA201007589B true ZA201007589B (en) | 2013-09-25 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2010/07589A ZA201007589B (en) | 2008-04-18 | 2010-10-25 | Antioxidant inflammation modulators: c-17 homologated oleanolic acid derivatives |
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Families Citing this family (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6326507B1 (en) | 1998-06-19 | 2001-12-04 | Trustees Of Dartmouth College | Therapeutic compounds and methods of use |
| KR101313702B1 (ko) | 2005-02-03 | 2013-10-04 | 와이어쓰 | 제피티니브 및/또는 에를로티니브 내성암 치료용 약제학적 조성물 |
| EP1942937A1 (en) | 2005-11-04 | 2008-07-16 | Wyeth | Antineoplastic combinations with mtor inhibitor, herceptin, and/or hki-272 |
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