ZA200405304B - Novel peptides as NS3-serine protease inhibitors of hepatitis C virus - Google Patents
Novel peptides as NS3-serine protease inhibitors of hepatitis C virus Download PDFInfo
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- ZA200405304B ZA200405304B ZA200405304A ZA200405304A ZA200405304B ZA 200405304 B ZA200405304 B ZA 200405304B ZA 200405304 A ZA200405304 A ZA 200405304A ZA 200405304 A ZA200405304 A ZA 200405304A ZA 200405304 B ZA200405304 B ZA 200405304B
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- 238000000034 method Methods 0.000 claims description 65
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0827—Tripeptides containing heteroatoms different from O, S, or N
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/052,386 US7244721B2 (en) | 2000-07-21 | 2002-01-18 | Peptides as NS3-serine protease inhibitors of hepatitis C virus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200405304B true ZA200405304B (en) | 2006-03-29 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200405304A ZA200405304B (en) | 2002-01-18 | 2004-07-02 | Novel peptides as NS3-serine protease inhibitors of hepatitis C virus |
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| Country | Link |
|---|---|
| US (2) | US7244721B2 (fr) |
| EP (1) | EP1481000B1 (fr) |
| JP (1) | JP4563033B2 (fr) |
| KR (1) | KR101020355B1 (fr) |
| CN (2) | CN101792483A (fr) |
| AR (1) | AR038183A1 (fr) |
| AT (1) | ATE469914T1 (fr) |
| AU (1) | AU2009210423B2 (fr) |
| BR (1) | BR0306931A (fr) |
| CA (1) | CA2473032A1 (fr) |
| CO (1) | CO5650168A2 (fr) |
| CY (1) | CY1111225T1 (fr) |
| DE (1) | DE60332814D1 (fr) |
| DK (1) | DK1481000T3 (fr) |
| EC (1) | ECSP045191A (fr) |
| IL (1) | IL162815A0 (fr) |
| MX (1) | MXPA04006934A (fr) |
| MY (1) | MY140710A (fr) |
| NO (1) | NO20042792L (fr) |
| NZ (1) | NZ571073A (fr) |
| PE (1) | PE20030852A1 (fr) |
| PL (1) | PL372747A1 (fr) |
| PT (1) | PT1481000E (fr) |
| RU (1) | RU2404189C9 (fr) |
| SI (1) | SI1481000T1 (fr) |
| TW (1) | TWI334872B (fr) |
| WO (1) | WO2003062265A2 (fr) |
| ZA (1) | ZA200405304B (fr) |
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- 2003-01-16 DK DK03731956.3T patent/DK1481000T3/da active
- 2003-01-16 EP EP03731956A patent/EP1481000B1/fr not_active Expired - Lifetime
- 2003-01-16 KR KR1020047011022A patent/KR101020355B1/ko not_active IP Right Cessation
- 2003-01-16 MY MYPI20030137A patent/MY140710A/en unknown
- 2003-01-16 CA CA002473032A patent/CA2473032A1/fr not_active Abandoned
- 2003-01-16 SI SI200331853T patent/SI1481000T1/sl unknown
- 2003-01-16 CN CN201010143451A patent/CN101792483A/zh active Pending
- 2003-01-16 MX MXPA04006934A patent/MXPA04006934A/es active IP Right Grant
- 2003-01-16 WO PCT/US2003/001430 patent/WO2003062265A2/fr active Search and Examination
- 2003-01-16 PE PE2003000049A patent/PE20030852A1/es not_active Application Discontinuation
- 2003-01-16 CN CNA038059339A patent/CN1633446A/zh active Pending
- 2003-01-16 JP JP2003562142A patent/JP4563033B2/ja not_active Expired - Fee Related
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- 2003-01-16 AT AT03731956T patent/ATE469914T1/de active
- 2003-01-16 RU RU2004125279/04A patent/RU2404189C9/ru not_active IP Right Cessation
- 2003-01-16 PT PT03731956T patent/PT1481000E/pt unknown
- 2003-01-17 AR ARP030100131A patent/AR038183A1/es unknown
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- 2004-07-02 NO NO20042792A patent/NO20042792L/no not_active Application Discontinuation
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