NO20042792L - Nye peptider som NS3-serinproteaseinhibitorer for hepatitt C-virus - Google Patents

Nye peptider som NS3-serinproteaseinhibitorer for hepatitt C-virus

Info

Publication number
NO20042792L
NO20042792L NO20042792A NO20042792A NO20042792L NO 20042792 L NO20042792 L NO 20042792L NO 20042792 A NO20042792 A NO 20042792A NO 20042792 A NO20042792 A NO 20042792A NO 20042792 L NO20042792 L NO 20042792L
Authority
NO
Norway
Prior art keywords
hepatitis
virus
protease inhibitors
serine protease
new peptides
Prior art date
Application number
NO20042792A
Other languages
English (en)
Inventor
Jesse K Wong
Viyyoor Moopil Girijavallabhan
Anil K Saksena
Raymond G Lovey
Russell E Pike
Yi-Tsung Liu
Marguerita S L Lim-Wilby
Ashit K Ganguly
Jinping L Mccormick
Ashok Arasappan
Srikanth Venkatraman
F George Njoroge
Tin-Yau Chan
Stephane L Bogen
Haiyan Wang
Tejal N Parekh
Patrick A Pinto
Bama Santhanam
Henry A Vaccaro
Scott Jeffrey Kemp
Original Assignee
Ustamura Susan Y
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ustamura Susan Y filed Critical Ustamura Susan Y
Publication of NO20042792L publication Critical patent/NO20042792L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0827—Tripeptides containing heteroatoms different from O, S, or N
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO20042792A 2002-01-18 2004-07-02 Nye peptider som NS3-serinproteaseinhibitorer for hepatitt C-virus NO20042792L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/052,386 US7244721B2 (en) 2000-07-21 2002-01-18 Peptides as NS3-serine protease inhibitors of hepatitis C virus
PCT/US2003/001430 WO2003062265A2 (en) 2002-01-18 2003-01-16 Novel peptides as ns3-serine protease inhibitors of hepatitis c virus

Publications (1)

Publication Number Publication Date
NO20042792L true NO20042792L (no) 2004-10-15

Family

ID=27609106

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20042792A NO20042792L (no) 2002-01-18 2004-07-02 Nye peptider som NS3-serinproteaseinhibitorer for hepatitt C-virus

Country Status (28)

Country Link
US (2) US7244721B2 (no)
EP (1) EP1481000B1 (no)
JP (1) JP4563033B2 (no)
KR (1) KR101020355B1 (no)
CN (2) CN1633446A (no)
AR (1) AR038183A1 (no)
AT (1) ATE469914T1 (no)
AU (1) AU2009210423B2 (no)
BR (1) BR0306931A (no)
CA (1) CA2473032A1 (no)
CO (1) CO5650168A2 (no)
CY (1) CY1111225T1 (no)
DE (1) DE60332814D1 (no)
DK (1) DK1481000T3 (no)
EC (1) ECSP045191A (no)
IL (1) IL162815A0 (no)
MX (1) MXPA04006934A (no)
MY (1) MY140710A (no)
NO (1) NO20042792L (no)
NZ (1) NZ571073A (no)
PE (1) PE20030852A1 (no)
PL (1) PL372747A1 (no)
PT (1) PT1481000E (no)
RU (1) RU2404189C9 (no)
SI (1) SI1481000T1 (no)
TW (1) TWI334872B (no)
WO (1) WO2003062265A2 (no)
ZA (1) ZA200405304B (no)

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