ATE261988T1 - Peptidomimetische inhibitoren von der protease des menschlichen cytomegalovirus - Google Patents
Peptidomimetische inhibitoren von der protease des menschlichen cytomegalovirusInfo
- Publication number
- ATE261988T1 ATE261988T1 AT97951048T AT97951048T ATE261988T1 AT E261988 T1 ATE261988 T1 AT E261988T1 AT 97951048 T AT97951048 T AT 97951048T AT 97951048 T AT97951048 T AT 97951048T AT E261988 T1 ATE261988 T1 AT E261988T1
- Authority
- AT
- Austria
- Prior art keywords
- human cytomegalovirus
- protease
- inhibitors
- peptidomimmetic
- hcmv
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1027—Tetrapeptides containing heteroatoms different from O, S, or N
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0827—Tripeptides containing heteroatoms different from O, S, or N
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3404196P | 1996-12-27 | 1996-12-27 | |
| US5286097P | 1997-07-17 | 1997-07-17 | |
| US5980697P | 1997-09-23 | 1997-09-23 | |
| PCT/CA1997/001004 WO1998029435A1 (en) | 1996-12-27 | 1997-12-23 | Peptidomimetic inhibitors of the human cytomegalovirus protease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE261988T1 true ATE261988T1 (de) | 2004-04-15 |
Family
ID=27364549
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97951048T ATE261988T1 (de) | 1996-12-27 | 1997-12-23 | Peptidomimetische inhibitoren von der protease des menschlichen cytomegalovirus |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6291640B1 (de) |
| EP (1) | EP0948523B1 (de) |
| JP (1) | JP2001508418A (de) |
| AT (1) | ATE261988T1 (de) |
| CA (1) | CA2276109C (de) |
| DE (1) | DE69728164D1 (de) |
| WO (1) | WO1998029435A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200404789A (en) * | 1999-03-15 | 2004-04-01 | Axys Pharm Inc | Novel compounds and compositions as protease inhibitors |
| US6649593B1 (en) * | 1999-10-13 | 2003-11-18 | Tularik Inc. | Modulators of SREBP processing |
| US6774212B2 (en) * | 1999-12-03 | 2004-08-10 | Bristol-Myers Squibb Pharma Company | Alpha-ketoamide inhibitors of hepatitis C virus NS3 protease |
| US7244721B2 (en) | 2000-07-21 | 2007-07-17 | Schering Corporation | Peptides as NS3-serine protease inhibitors of hepatitis C virus |
| AU2001276988B2 (en) | 2000-07-21 | 2007-01-25 | Dendreon Corporation | Peptides as NS3-serine protease inhibitors of hepatitis C virus |
| RU2003105221A (ru) * | 2000-07-21 | 2004-09-20 | Шеринг Корпорейшн (US) | Новые пептиды, как ингибиторы ns3-серинпротеазы вируса гепатита с |
| US6599940B2 (en) | 2000-09-13 | 2003-07-29 | Georgetown University | Synthesis of 2-hydroxymethylglutamic acid and congeners thereof |
| US7153822B2 (en) * | 2002-01-29 | 2006-12-26 | Wyeth | Compositions and methods for modulating connexin hemichannels |
| CA3026074A1 (en) | 2016-06-01 | 2017-12-07 | M3 Biotechnology, Inc. | N-hexanoic-l-tyrosine-l-isoleucine-(6)-aminohexanoic amide compounds and their use to treat neurodegenerative diseases |
| GB2563396B (en) * | 2017-06-12 | 2020-09-23 | Ustav Organicke Chemie A Biochemie Av Cr V V I | Inhibitors of Rhomboid Intramembrane Proteases |
| WO2022265577A2 (en) * | 2021-06-15 | 2022-12-22 | Agency For Science, Technology And Research | Coronavirus enzyme modulators, methods of synthesis and uses thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA905737B (en) * | 1989-07-26 | 1991-05-29 | Merrell Dow Pharma | Novel peptidase inhibitors |
| AU6977096A (en) | 1995-09-14 | 1997-04-01 | Cephalon, Inc. | Ketomethylene group-containing cysteine and serine protease inhibitors |
-
1997
- 1997-12-23 US US09/171,554 patent/US6291640B1/en not_active Expired - Fee Related
- 1997-12-23 JP JP52951198A patent/JP2001508418A/ja active Pending
- 1997-12-23 AT AT97951048T patent/ATE261988T1/de not_active IP Right Cessation
- 1997-12-23 DE DE69728164T patent/DE69728164D1/de not_active Expired - Lifetime
- 1997-12-23 CA CA002276109A patent/CA2276109C/en not_active Expired - Fee Related
- 1997-12-23 EP EP97951048A patent/EP0948523B1/de not_active Expired - Lifetime
- 1997-12-23 WO PCT/CA1997/001004 patent/WO1998029435A1/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| DE69728164D1 (de) | 2004-04-22 |
| US6291640B1 (en) | 2001-09-18 |
| JP2001508418A (ja) | 2001-06-26 |
| EP0948523A1 (de) | 1999-10-13 |
| EP0948523B1 (de) | 2004-03-17 |
| CA2276109C (en) | 2003-11-18 |
| CA2276109A1 (en) | 1998-07-09 |
| WO1998029435A1 (en) | 1998-07-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |