ZA200304545B - Peptides and/or proteins and use thereof for the production of a therapeutic and/or prophylactic medicament. - Google Patents

Peptides and/or proteins and use thereof for the production of a therapeutic and/or prophylactic medicament. Download PDF

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Publication number
ZA200304545B
ZA200304545B ZA200304545A ZA200304545A ZA200304545B ZA 200304545 B ZA200304545 B ZA 200304545B ZA 200304545 A ZA200304545 A ZA 200304545A ZA 200304545 A ZA200304545 A ZA 200304545A ZA 200304545 B ZA200304545 B ZA 200304545B
Authority
ZA
South Africa
Prior art keywords
residue
pharmaceutical composition
denotes
peptides
preparation
Prior art date
Application number
ZA200304545A
Other languages
English (en)
Inventor
Peter Petzelbauer
Original Assignee
Fibrex Medical Researh & Dev G
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fibrex Medical Researh & Dev G filed Critical Fibrex Medical Researh & Dev G
Publication of ZA200304545B publication Critical patent/ZA200304545B/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36Blood coagulation or fibrinolysis factors
    • A61K38/363Fibrinogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • C07K14/75Fibrinogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0804Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1002Tetrapeptides with the first amino acid being neutral
    • C07K5/1005Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1008Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Vascular Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
ZA200304545A 2000-12-12 2004-06-11 Peptides and/or proteins and use thereof for the production of a therapeutic and/or prophylactic medicament. ZA200304545B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT20632000 2000-12-12

Publications (1)

Publication Number Publication Date
ZA200304545B true ZA200304545B (en) 2004-09-13

Family

ID=3689750

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200304545A ZA200304545B (en) 2000-12-12 2004-06-11 Peptides and/or proteins and use thereof for the production of a therapeutic and/or prophylactic medicament.

Country Status (31)

Country Link
US (4) US7271144B2 (ja)
EP (2) EP1341819B1 (ja)
JP (1) JP4181874B2 (ja)
KR (1) KR100864069B1 (ja)
CN (2) CN101676299A (ja)
AT (2) ATE425184T1 (ja)
AU (1) AU2002221316A1 (ja)
BG (1) BG107891A (ja)
BR (1) BR0116122A (ja)
CA (1) CA2430972C (ja)
CY (2) CY1106108T1 (ja)
CZ (1) CZ20031630A3 (ja)
DE (2) DE50110182D1 (ja)
DK (2) DK1341819T3 (ja)
EA (1) EA005576B1 (ja)
EE (1) EE200300283A (ja)
ES (2) ES2323963T3 (ja)
HK (1) HK1084400A1 (ja)
HR (1) HRP20030564A2 (ja)
HU (1) HUP0401536A3 (ja)
IL (2) IL156360A0 (ja)
MX (1) MXPA03005218A (ja)
NO (1) NO330767B1 (ja)
NZ (1) NZ550619A (ja)
PL (2) PL209419B1 (ja)
PT (2) PT1586586E (ja)
SI (2) SI1341819T1 (ja)
SK (1) SK7062003A3 (ja)
WO (1) WO2002048180A2 (ja)
YU (1) YU53803A (ja)
ZA (1) ZA200304545B (ja)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL209419B1 (pl) 2000-12-12 2011-08-31 Fibrex Medical Res & Dev Gmbh Zastosowanie peptydów lub białek do wytwarzania leku do terapeutycznego i/lub profilaktycznego stosowania w przypadku zapaleń w medycynie i/lub weterynarii
JP2008503503A (ja) * 2004-06-25 2008-02-07 ファイブレックス メディカル リサーチ アンド デベロップメント ゲーエムベーハー ヒトフィブリノゲンのAα鎖またはBβ鎖由来のペプチドの、ショックの治療のための利用
FR2879604B1 (fr) * 2004-12-22 2010-08-13 Biomerieux Sa Peptides citrullines derives de la fibrine reconnus par des auto-anticorps specifiques de la polyarthrite rhumatoide, et leurs utilisations
AT502987A1 (de) 2005-12-23 2007-07-15 Fibrex Medical Res & Dev Gmbh Pharmazeutische zusammensetzung zur behandlung von hämorrhagischem schock und seinen folgeerscheinungen
DE602007002553D1 (de) * 2006-02-23 2009-11-05 Fibrex Medical Res & Dev Gmbh Ihre verwendung zur herstellung einer therapeutisch und/oder prophylaktisch wirksamen pharmazeutischen zusammensetzung
ZA200807028B (en) * 2006-02-23 2009-11-25 Fibrex Medical Res & Dev Gmbh Peptides and peptide derivatives as well as pharmaceutical compositions containing the same
WO2007095659A1 (de) * 2006-02-23 2007-08-30 Fibrex Medical Research & Development Gmbh Peptide und peptid-derivate, herstellun derselben sowie deren verwendung zur herstellung eines therapeutisch und/oder präventiv wirkenden arzneimittels
FR2900657B1 (fr) * 2006-05-03 2009-04-17 Univ Toulouse Identification de modulateurs de l'activation des macrophages, utilisables pour le traitement de la polyarthrite rhumatoide
US8722623B2 (en) 2007-09-17 2014-05-13 University Of Maryland, Baltimore Compositions and methods utilizing fibrin beta chain fragments
FR2908134B1 (fr) * 2007-12-04 2012-10-12 Univ Toulouse 3 Paul Sabatier Identification de modulateurs de l'activation des macrophages, utilisables pour le traitement de la polyarthrite rhumatoide
JP5410997B2 (ja) * 2008-01-31 2014-02-05 則行 川村 うつ病およびうつ状態のマーカーおよびそれを用いた検出・診断
US20090286725A1 (en) * 2008-05-15 2009-11-19 Fibrex Medical Research & Development Gmbh Peptides and derivatives thereof, the manufacturing thereof as well as their use for preparing a therapeutically and/or preventively active pharmaceutical composition
US8088890B2 (en) * 2008-09-26 2012-01-03 Fibrex Medical Research & Development Gmbh Peptides and peptidomimetic compounds, the manufacturing thereof as well as their use for preparing a therapeutically and/or preventively active pharmaceutical composition
WO2010043444A2 (en) * 2008-10-15 2010-04-22 Fibrex Medical Research & Development Gmbh Pharmaceutical preparation for the treatment and/or prevention of ischemia/reperfusion injury and the sequels thereof
US20100152832A1 (en) * 2008-12-12 2010-06-17 Medtronic Vascular, Inc. Apparatus and Methods for Treatment of Aneurysms With Fibrin Derived Peptide B-Beta
WO2013082458A1 (en) 2011-12-02 2013-06-06 The Regents Of The University Of California Reperfusion protection solution and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4927916A (en) 1984-04-23 1990-05-22 The General Hospital Corporation Method of producing fibrin-specific monoclonal antibodies lacking fibrinogen-cross-reactivity using fibrin-specific peptides
US5965107A (en) * 1992-03-13 1999-10-12 Diatide, Inc. Technetium-99m labeled peptides for imaging
DE19729591A1 (de) * 1997-07-10 1999-02-11 Therasorb Medizinische Systeme Mittel zur Behandlung und/oder Prophylaxe von Mikrozirkulationsstörungen
FR2795735B1 (fr) * 1999-07-01 2001-09-07 Univ Toulouse Derives citrullines de la fibrine et leur utilisation pour le diagnostic ou le traitement de la polyarthrite rhumatoide
PL209419B1 (pl) 2000-12-12 2011-08-31 Fibrex Medical Res & Dev Gmbh Zastosowanie peptydów lub białek do wytwarzania leku do terapeutycznego i/lub profilaktycznego stosowania w przypadku zapaleń w medycynie i/lub weterynarii
US7201763B2 (en) * 2001-10-24 2007-04-10 Boston Scientific Scimed, Inc. Distal balloon waist material relief and method of manufacture

Also Published As

Publication number Publication date
PT1341819E (pt) 2006-10-31
EP1586586A2 (de) 2005-10-19
CY1109107T1 (el) 2014-07-02
ES2323963T3 (es) 2009-07-28
IL156360A (en) 2012-12-31
PT1586586E (pt) 2010-05-28
KR100864069B1 (ko) 2008-10-16
SI1341819T1 (sl) 2006-10-31
US20040192596A1 (en) 2004-09-30
US20090088384A1 (en) 2009-04-02
SK7062003A3 (en) 2003-11-04
US20070037749A1 (en) 2007-02-15
CA2430972C (en) 2014-08-05
EP1341819B1 (de) 2006-06-14
CN1518558A (zh) 2004-08-04
NO20032656L (no) 2003-06-12
BR0116122A (pt) 2003-10-14
KR20030060988A (ko) 2003-07-16
DE50110182D1 (de) 2006-07-27
AU2002221316A1 (en) 2002-06-24
EA005576B1 (ru) 2005-04-28
SI1586586T1 (sl) 2009-08-31
CN101676299A (zh) 2010-03-24
DK1341819T3 (da) 2006-10-16
ATE425184T1 (de) 2009-03-15
PL362924A1 (en) 2004-11-02
US7811985B2 (en) 2010-10-12
PL209419B1 (pl) 2011-08-31
NO20032656D0 (no) 2003-06-12
HRP20030564A2 (en) 2005-06-30
EP1341819A2 (de) 2003-09-10
EP1586586A3 (de) 2006-03-29
HUP0401536A3 (en) 2008-09-29
US7271144B2 (en) 2007-09-18
CA2430972A1 (en) 2002-06-20
US7494973B2 (en) 2009-02-24
IL156360A0 (en) 2004-01-04
BG107891A (bg) 2004-08-31
EA200300678A1 (ru) 2003-10-30
CN1518558B (zh) 2010-06-16
CY1106108T1 (el) 2011-06-08
DE50114771D1 (de) 2009-04-23
JP4181874B2 (ja) 2008-11-19
PL209752B1 (pl) 2011-10-31
HUP0401536A2 (hu) 2004-11-29
WO2002048180A3 (de) 2003-01-30
EP1586586B1 (de) 2009-03-11
ES2266093T3 (es) 2007-03-01
NZ550619A (en) 2008-06-30
JP2004527469A (ja) 2004-09-09
US20090137464A1 (en) 2009-05-28
YU53803A (sh) 2006-03-03
WO2002048180A2 (de) 2002-06-20
US8067373B2 (en) 2011-11-29
MXPA03005218A (es) 2004-12-03
HK1084400A1 (en) 2006-07-28
EE200300283A (et) 2003-10-15
DK1586586T3 (da) 2009-06-29
NO330767B1 (no) 2011-07-11
ATE329614T1 (de) 2006-07-15
CZ20031630A3 (cs) 2003-10-15

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