BR0116122A - Peptìdeos e/ou proteìnas bem como seu uso para preparar uma composição farmacêutica, terapêutica e/ou preventiva - Google Patents

Peptìdeos e/ou proteìnas bem como seu uso para preparar uma composição farmacêutica, terapêutica e/ou preventiva

Info

Publication number
BR0116122A
BR0116122A BR0116122-9A BR0116122A BR0116122A BR 0116122 A BR0116122 A BR 0116122A BR 0116122 A BR0116122 A BR 0116122A BR 0116122 A BR0116122 A BR 0116122A
Authority
BR
Brazil
Prior art keywords
therapeutic
well
peptides
proteins
pharmaceutical
Prior art date
Application number
BR0116122-9A
Other languages
English (en)
Inventor
Peter Petzelbauer
Original Assignee
Fibrex Medical Res & Dev Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fibrex Medical Res & Dev Gmbh filed Critical Fibrex Medical Res & Dev Gmbh
Publication of BR0116122A publication Critical patent/BR0116122A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/363—Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/75—Fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Toxicology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

"PEPTìDEOS E/OU PROTEìNAS BEM COMO SEU USO PARA PREPARAR UMA COMPOSIçãO FARMACêUTICA, TERAPêUTICA E/OU PREVENTIVA". A invenção refere-se a peptídeos ou proteínas de fórmula geral (I), na qual R~ 1~ e R~ 2~ independentemente = hidrogênio, um grupo de hidrocarboneto saturado ou insaturado com 1 a 3, em particular até 10 átomos de carbono, Z~ 1~ = denota um grupo de histidina ou prolina, Z~ 2~ = um grupo de arginina, um grupo de peptídeo ou grupo de proteína com arginina na terminação inicial, em particular com 2 a 30 aminoácidos, e os sais destes, bem como, por exemplo as amidas destes, ou misturas de material destes e/ou com pelo menos um outro material. (I) pode ser empregada para aplicações terapêuticas e/ou profiláticas em medicina humana e/ou veterinária.
BR0116122-9A 2000-12-12 2001-12-07 Peptìdeos e/ou proteìnas bem como seu uso para preparar uma composição farmacêutica, terapêutica e/ou preventiva BR0116122A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT20632000 2000-12-12
PCT/AT2001/000387 WO2002048180A2 (de) 2000-12-12 2001-12-07 Peptide und/oder proteine sowie verwendung desselben zur herstellung eines therapeutischen und/oder präventiven arzneimittels

Publications (1)

Publication Number Publication Date
BR0116122A true BR0116122A (pt) 2003-10-14

Family

ID=3689750

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0116122-9A BR0116122A (pt) 2000-12-12 2001-12-07 Peptìdeos e/ou proteìnas bem como seu uso para preparar uma composição farmacêutica, terapêutica e/ou preventiva

Country Status (31)

Country Link
US (4) US7271144B2 (pt)
EP (2) EP1586586B1 (pt)
JP (1) JP4181874B2 (pt)
KR (1) KR100864069B1 (pt)
CN (2) CN1518558B (pt)
AT (2) ATE425184T1 (pt)
AU (1) AU2002221316A1 (pt)
BG (1) BG107891A (pt)
BR (1) BR0116122A (pt)
CA (1) CA2430972C (pt)
CY (2) CY1106108T1 (pt)
CZ (1) CZ20031630A3 (pt)
DE (2) DE50110182D1 (pt)
DK (2) DK1341819T3 (pt)
EA (1) EA005576B1 (pt)
EE (1) EE200300283A (pt)
ES (2) ES2323963T3 (pt)
HK (1) HK1084400A1 (pt)
HR (1) HRP20030564A2 (pt)
HU (1) HUP0401536A3 (pt)
IL (2) IL156360A0 (pt)
MX (1) MXPA03005218A (pt)
NO (1) NO330767B1 (pt)
NZ (1) NZ550619A (pt)
PL (2) PL209752B1 (pt)
PT (2) PT1586586E (pt)
SI (2) SI1341819T1 (pt)
SK (1) SK7062003A3 (pt)
WO (1) WO2002048180A2 (pt)
YU (1) YU53803A (pt)
ZA (1) ZA200304545B (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1518558B (zh) 2000-12-12 2010-06-16 菲布雷克斯医疗研究及开发有限责任公司 肽和/或蛋白质及其用于制备治疗性和/或预防性药物组合物的用途
AU2005256121B2 (en) * 2004-06-25 2011-03-03 Fibrex Medical Research & Development Gmbh Use of peptides derived from the A alpha or B beta chain of human fibrinogen for the treatment of shock
FR2879604B1 (fr) * 2004-12-22 2010-08-13 Biomerieux Sa Peptides citrullines derives de la fibrine reconnus par des auto-anticorps specifiques de la polyarthrite rhumatoide, et leurs utilisations
AT502987A1 (de) 2005-12-23 2007-07-15 Fibrex Medical Res & Dev Gmbh Pharmazeutische zusammensetzung zur behandlung von hämorrhagischem schock und seinen folgeerscheinungen
WO2007095659A1 (de) * 2006-02-23 2007-08-30 Fibrex Medical Research & Development Gmbh Peptide und peptid-derivate, herstellun derselben sowie deren verwendung zur herstellung eines therapeutisch und/oder präventiv wirkenden arzneimittels
US20110098442A1 (en) * 2006-02-23 2011-04-28 Fibrex Medical Research & Development Gmbh Peptides and peptide derivatives as well as pharmaceutical compositions containing the same
DE602007002553D1 (de) * 2006-02-23 2009-11-05 Fibrex Medical Res & Dev Gmbh Ihre verwendung zur herstellung einer therapeutisch und/oder prophylaktisch wirksamen pharmazeutischen zusammensetzung
FR2900657B1 (fr) 2006-05-03 2009-04-17 Univ Toulouse Identification de modulateurs de l'activation des macrophages, utilisables pour le traitement de la polyarthrite rhumatoide
WO2009038729A2 (en) 2007-09-17 2009-03-26 Regenerx Biopharmaceuticals, Inc. Compositions and methods utilizing fibrin beta chain fragments of the bbeta chain of fibrinogen
FR2908134B1 (fr) * 2007-12-04 2012-10-12 Univ Toulouse 3 Paul Sabatier Identification de modulateurs de l'activation des macrophages, utilisables pour le traitement de la polyarthrite rhumatoide
JP5410997B2 (ja) * 2008-01-31 2014-02-05 則行 川村 うつ病およびうつ状態のマーカーおよびそれを用いた検出・診断
US20090286725A1 (en) * 2008-05-15 2009-11-19 Fibrex Medical Research & Development Gmbh Peptides and derivatives thereof, the manufacturing thereof as well as their use for preparing a therapeutically and/or preventively active pharmaceutical composition
US8088890B2 (en) 2008-09-26 2012-01-03 Fibrex Medical Research & Development Gmbh Peptides and peptidomimetic compounds, the manufacturing thereof as well as their use for preparing a therapeutically and/or preventively active pharmaceutical composition
WO2010043444A2 (en) * 2008-10-15 2010-04-22 Fibrex Medical Research & Development Gmbh Pharmaceutical preparation for the treatment and/or prevention of ischemia/reperfusion injury and the sequels thereof
US20100152832A1 (en) * 2008-12-12 2010-06-17 Medtronic Vascular, Inc. Apparatus and Methods for Treatment of Aneurysms With Fibrin Derived Peptide B-Beta
US10531655B2 (en) 2011-12-02 2020-01-14 The Regents Of The University Of California Reperfusion protection solution and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4927916A (en) * 1984-04-23 1990-05-22 The General Hospital Corporation Method of producing fibrin-specific monoclonal antibodies lacking fibrinogen-cross-reactivity using fibrin-specific peptides
US5965107A (en) * 1992-03-13 1999-10-12 Diatide, Inc. Technetium-99m labeled peptides for imaging
DE19729591A1 (de) * 1997-07-10 1999-02-11 Therasorb Medizinische Systeme Mittel zur Behandlung und/oder Prophylaxe von Mikrozirkulationsstörungen
FR2795735B1 (fr) * 1999-07-01 2001-09-07 Univ Toulouse Derives citrullines de la fibrine et leur utilisation pour le diagnostic ou le traitement de la polyarthrite rhumatoide
CN1518558B (zh) * 2000-12-12 2010-06-16 菲布雷克斯医疗研究及开发有限责任公司 肽和/或蛋白质及其用于制备治疗性和/或预防性药物组合物的用途
US7201763B2 (en) 2001-10-24 2007-04-10 Boston Scientific Scimed, Inc. Distal balloon waist material relief and method of manufacture

Also Published As

Publication number Publication date
CN101676299A (zh) 2010-03-24
EP1586586A2 (de) 2005-10-19
CN1518558A (zh) 2004-08-04
DK1341819T3 (da) 2006-10-16
PL209419B1 (pl) 2011-08-31
DK1586586T3 (da) 2009-06-29
US8067373B2 (en) 2011-11-29
US7271144B2 (en) 2007-09-18
HUP0401536A3 (en) 2008-09-29
HK1084400A1 (en) 2006-07-28
CN1518558B (zh) 2010-06-16
ATE425184T1 (de) 2009-03-15
KR20030060988A (ko) 2003-07-16
CY1109107T1 (el) 2014-07-02
ES2266093T3 (es) 2007-03-01
NO330767B1 (no) 2011-07-11
WO2002048180A2 (de) 2002-06-20
PL362924A1 (en) 2004-11-02
US7811985B2 (en) 2010-10-12
DE50114771D1 (de) 2009-04-23
ATE329614T1 (de) 2006-07-15
US7494973B2 (en) 2009-02-24
CA2430972C (en) 2014-08-05
US20090137464A1 (en) 2009-05-28
IL156360A0 (en) 2004-01-04
WO2002048180A3 (de) 2003-01-30
EA200300678A1 (ru) 2003-10-30
AU2002221316A1 (en) 2002-06-24
CA2430972A1 (en) 2002-06-20
PT1586586E (pt) 2010-05-28
EA005576B1 (ru) 2005-04-28
EP1341819A2 (de) 2003-09-10
HUP0401536A2 (hu) 2004-11-29
EE200300283A (et) 2003-10-15
PL209752B1 (pl) 2011-10-31
US20070037749A1 (en) 2007-02-15
YU53803A (sh) 2006-03-03
EP1586586A3 (de) 2006-03-29
DE50110182D1 (de) 2006-07-27
HRP20030564A2 (en) 2005-06-30
NO20032656L (no) 2003-06-12
EP1341819B1 (de) 2006-06-14
BG107891A (bg) 2004-08-31
JP2004527469A (ja) 2004-09-09
ZA200304545B (en) 2004-09-13
IL156360A (en) 2012-12-31
NZ550619A (en) 2008-06-30
SI1586586T1 (sl) 2009-08-31
PT1341819E (pt) 2006-10-31
KR100864069B1 (ko) 2008-10-16
NO20032656D0 (no) 2003-06-12
EP1586586B1 (de) 2009-03-11
CY1106108T1 (el) 2011-06-08
MXPA03005218A (es) 2004-12-03
US20040192596A1 (en) 2004-09-30
US20090088384A1 (en) 2009-04-02
ES2323963T3 (es) 2009-07-28
SI1341819T1 (sl) 2006-10-31
JP4181874B2 (ja) 2008-11-19
SK7062003A3 (en) 2003-11-04
CZ20031630A3 (cs) 2003-10-15

Similar Documents

Publication Publication Date Title
BR0116122A (pt) Peptìdeos e/ou proteìnas bem como seu uso para preparar uma composição farmacêutica, terapêutica e/ou preventiva
Takagi et al. Amino acid sequence studies on the α chain of human fibrinogen. Location of four plasmin attack points and a covalent cross-linking site
DE69123754T2 (de) Peptidische hemmer der hiv-replikation
BRPI0511421A (pt) composições cosmética e farmacêutica para tratar materiais contendo queratina, uso de composições cosméticas, molécula efetora que liga queratina, uso da mesma, e, processo
BRPI0406800B8 (pt) "dímero de peptídeo, composição farmacêutica contendo o mesmo e seu uso
HANSEN et al. Structure–activity relationships in enkephalin peptides
BR9714434A (pt) Formulações de interferon liquidas estáveis
CY1110973T1 (el) Βελτιωμενα διμερη sgp130fc
EA200000652A1 (ru) Кристаллы глюкагоноподобного пептида 1
BRPI0820956A8 (pt) Composição nutricional enteral líquida esterilizada, método para produzir a composição, uso de uma composição nutricional, e, uso simultâneo ou seqüencial de caseína micelar e, opcionalmente, caseinato
BR0309877A (pt) Peptìdeos estimuladores de tecido conectivo
ATE165836T1 (de) Peptide als arzneimittel
BR0009472A (pt) Antagonistas de lhrh com propriedades desolubilidade aperfeiçoadas
IL173969A0 (en) Use of peptides derived from the a alpha or b beta chain of human of human fibrinogen for the treatment of shock
ATE365542T1 (de) Lyophilisierbare pharmazeutische plazebozusammensetzung , insbesondere auf basis von proteinen oder polypeptiden, zur nachahmung eines arzneimittels
AR035077A1 (es) Polipeptidos de neublastina variante, proteinas de fusion, acidos nucleicos, vectores, celulas hospedadoras, metodos para producir dichos polipeptidos, dimeros, conjugados, composiciones farmaceuticas y uso de dichos polipeptidos en la preparacion de medicamentos
Block et al. Amino acids in posterior pituitary protein
BR9809103A (pt) Forma farmacêutica estável de administração para peptìdeos, proteìnas e ácidos nucléicos
ATE355302T1 (de) N-substituierte d-aminosäuren enthaltende peptide,zur prävention der beta-strang assoziation
ATE3416T1 (de) Pharmakologisch aktive peptide und diese enthaltende arzneimittel.
BR0109279A (pt) Antagonistas de lhrh, sua preparação e aplicação como medicamento
BR0014803A (pt) Peptìdeo, composição farmacêutica, uso de um ou mais dos peptìdeos, e, composição de diagnóstico
DE69839733D1 (de) Mit syndekan interagierende proteine und deren verwendung
Gerdin et al. Structural requirements for microvascular permeability-increasing ability of peptides: Studies on analogues of a fibrinogen pentapeptide fragment
Rohde et al. Structure of antigenic determinants in the N-terminal region of dermatosparactic sheep procollagen type I

Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]