FR2879604B1 - Peptides citrullines derives de la fibrine reconnus par des auto-anticorps specifiques de la polyarthrite rhumatoide, et leurs utilisations - Google Patents

Peptides citrullines derives de la fibrine reconnus par des auto-anticorps specifiques de la polyarthrite rhumatoide, et leurs utilisations

Info

Publication number
FR2879604B1
FR2879604B1 FR0413711A FR0413711A FR2879604B1 FR 2879604 B1 FR2879604 B1 FR 2879604B1 FR 0413711 A FR0413711 A FR 0413711A FR 0413711 A FR0413711 A FR 0413711A FR 2879604 B1 FR2879604 B1 FR 2879604B1
Authority
FR
France
Prior art keywords
citrulin
rhe
fibrin
antibodies
patient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR0413711A
Other languages
English (en)
Other versions
FR2879604A1 (fr
Inventor
Olivier Serre
Mireille Sebbag
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biomerieux SA
Original Assignee
Biomerieux SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0413711A priority Critical patent/FR2879604B1/fr
Application filed by Biomerieux SA filed Critical Biomerieux SA
Priority to US11/577,674 priority patent/US8207299B2/en
Priority to DE602005008277T priority patent/DE602005008277D1/de
Priority to EP05815291A priority patent/EP1814901B1/fr
Priority to AT05815291T priority patent/ATE401338T1/de
Priority to ES05815291T priority patent/ES2310853T3/es
Priority to PCT/FR2005/002736 priority patent/WO2006048556A1/fr
Priority to JP2007538475A priority patent/JP5060300B2/ja
Publication of FR2879604A1 publication Critical patent/FR2879604A1/fr
Application granted granted Critical
Publication of FR2879604B1 publication Critical patent/FR2879604B1/fr
Priority to US13/489,072 priority patent/US9249208B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/75—Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Rheumatology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
FR0413711A 2004-11-04 2004-12-22 Peptides citrullines derives de la fibrine reconnus par des auto-anticorps specifiques de la polyarthrite rhumatoide, et leurs utilisations Active FR2879604B1 (fr)

Priority Applications (9)

Application Number Priority Date Filing Date Title
FR0413711A FR2879604B1 (fr) 2004-12-22 2004-12-22 Peptides citrullines derives de la fibrine reconnus par des auto-anticorps specifiques de la polyarthrite rhumatoide, et leurs utilisations
DE602005008277T DE602005008277D1 (de) 2004-11-04 2005-11-03 Von fibrin abgeleitete citrullinpeptide, die durch für rheumatoide arthritis spezifische autoantikörper erkannt werden, und deren verwendung
EP05815291A EP1814901B1 (fr) 2004-11-04 2005-11-03 Peptides citrullines derives de la fibrine reconnus par des auto-anticorps specifiques de la polyartrhite rhumatoide, et leurs utilisations
AT05815291T ATE401338T1 (de) 2004-11-04 2005-11-03 Von fibrin abgeleitete citrullinpeptide, die durch für rheumatoide arthritis spezifische autoantikörper erkannt werden, und deren verwendung
US11/577,674 US8207299B2 (en) 2004-11-04 2005-11-03 Citrulline peptides derived from fibrin and recognized by rheumatoid arthritis specific autoantibodies, and the use thereof
ES05815291T ES2310853T3 (es) 2004-11-04 2005-11-03 Peptidos citrulinados derivados de la fibrina reconocidos por autoanticuerpos especificos de la poliartritis reumatoide y usos de los mismos.
PCT/FR2005/002736 WO2006048556A1 (fr) 2004-11-04 2005-11-03 Peptides citrullines derives de la fibrine reconnus par des auto-anticorps specifiques de la polyartrhite rhumatoide, et leurs utilisations
JP2007538475A JP5060300B2 (ja) 2004-11-04 2005-11-03 リウマチ性関節炎特異的自己抗体により認識されるフィブリン由来シトルリンペプチド、及びその使用
US13/489,072 US9249208B2 (en) 2004-11-04 2012-06-05 Citrulline peptides derived from fibrin and recognized by rheumatoid arthritis specific autoantibodies, and the use thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0413711A FR2879604B1 (fr) 2004-12-22 2004-12-22 Peptides citrullines derives de la fibrine reconnus par des auto-anticorps specifiques de la polyarthrite rhumatoide, et leurs utilisations

Publications (2)

Publication Number Publication Date
FR2879604A1 FR2879604A1 (fr) 2006-06-23
FR2879604B1 true FR2879604B1 (fr) 2010-08-13

Family

ID=34952648

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0413711A Active FR2879604B1 (fr) 2004-11-04 2004-12-22 Peptides citrullines derives de la fibrine reconnus par des auto-anticorps specifiques de la polyarthrite rhumatoide, et leurs utilisations

Country Status (1)

Country Link
FR (1) FR2879604B1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2307421B1 (es) * 2007-04-30 2009-09-28 Consejo Superiorde Investigaciones Cientificas (Csic) Polipeptido quimerico fibrina-filagrina citruinado capaz de detectar los anticuerpos generados en la artritis reumatoide.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2795735B1 (fr) * 1999-07-01 2001-09-07 Univ Toulouse Derives citrullines de la fibrine et leur utilisation pour le diagnostic ou le traitement de la polyarthrite rhumatoide
CZ20031630A3 (cs) * 2000-12-12 2003-10-15 Fibrex Medical Research & Development Gmbh Peptidy a/nebo proteiny a jejich použití pro přípravu terapeutického a/nebo preventivního farmaceutického přípravku
US6908899B2 (en) * 2001-08-17 2005-06-21 U.S. Dept. Of Veterans Affairs Pro-inflammatory fibrinopeptide
NL1019540C2 (nl) * 2001-12-11 2003-07-01 Stichting Tech Wetenschapp Werkwijze voor het detecteren van auto-antilichamen van patienten die lijden aan reumatoïde artritis, peptide en assaykit.

Also Published As

Publication number Publication date
FR2879604A1 (fr) 2006-06-23

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