EA200702643A1 - Антитела, связывающие tweak - Google Patents

Антитела, связывающие tweak

Info

Publication number
EA200702643A1
EA200702643A1 EA200702643A EA200702643A EA200702643A1 EA 200702643 A1 EA200702643 A1 EA 200702643A1 EA 200702643 A EA200702643 A EA 200702643A EA 200702643 A EA200702643 A EA 200702643A EA 200702643 A1 EA200702643 A1 EA 200702643A1
Authority
EA
Eurasian Patent Office
Prior art keywords
tweak antibodies
tweak
antibodies
antibodies against
against tweak
Prior art date
Application number
EA200702643A
Other languages
English (en)
Other versions
EA018255B1 (ru
Inventor
Линда К. Беркли
Эллен Гарбер
Алексей Луговской
Original Assignee
Байоджен Айдек Ма Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Байоджен Айдек Ма Инк. filed Critical Байоджен Айдек Ма Инк.
Publication of EA200702643A1 publication Critical patent/EA200702643A1/ru
Publication of EA018255B1 publication Critical patent/EA018255B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Abstract

Описываются антитела против TWEAK.
EA200702643A 2005-05-27 2006-05-25 Белки, связывающие tweak, и их применение EA018255B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68514905P 2005-05-27 2005-05-27
PCT/US2006/019706 WO2006130374A2 (en) 2005-05-27 2006-05-25 Tweak binding antibodies

Publications (2)

Publication Number Publication Date
EA200702643A1 true EA200702643A1 (ru) 2008-04-28
EA018255B1 EA018255B1 (ru) 2013-06-28

Family

ID=37482143

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200702643A EA018255B1 (ru) 2005-05-27 2006-05-25 Белки, связывающие tweak, и их применение

Country Status (30)

Country Link
US (2) US8048422B2 (ru)
EP (3) EP2460831B1 (ru)
JP (4) JP5175181B2 (ru)
KR (2) KR20080023317A (ru)
CN (3) CN101247830B (ru)
AU (1) AU2006252830B2 (ru)
BR (1) BRPI0611414B8 (ru)
CA (1) CA2609600C (ru)
CY (1) CY1118343T1 (ru)
DK (2) DK2460831T3 (ru)
EA (1) EA018255B1 (ru)
ES (2) ES2507069T3 (ru)
GE (1) GEP20115324B (ru)
HK (3) HK1116423A1 (ru)
HU (1) HUE030701T2 (ru)
IL (1) IL187585A (ru)
IS (1) IS8693A (ru)
LT (1) LT2460831T (ru)
ME (2) MEP35408A (ru)
MX (1) MX339015B (ru)
NO (1) NO20076607L (ru)
NZ (2) NZ583636A (ru)
PL (3) PL218791B1 (ru)
PT (2) PT1888113E (ru)
RS (1) RS55888B1 (ru)
SG (1) SG162728A1 (ru)
SI (2) SI1888113T1 (ru)
UA (1) UA96416C2 (ru)
WO (1) WO2006130374A2 (ru)
ZA (1) ZA200710765B (ru)

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CA2587018A1 (en) * 2004-11-08 2006-05-18 University Of Maryland, Baltimore Tweak as a therapeutic target for treating central nervous system diseases associated with cerebral edema and cell death
US7939490B2 (en) 2004-12-13 2011-05-10 University Of Maryland, Baltimore TWEAK as a therapeutic target for treating central nervous system diseases associated with cerebral edema and cell death
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Also Published As

Publication number Publication date
ES2605945T3 (es) 2017-03-17
AU2006252830B2 (en) 2012-11-22
HK1121072A1 (en) 2009-04-17
BRPI0611414B1 (pt) 2019-04-16
WO2006130374A3 (en) 2007-12-13
KR20130140230A (ko) 2013-12-23
WO2006130374A2 (en) 2006-12-07
ZA200710765B (en) 2009-09-30
KR101679468B1 (ko) 2016-11-24
CN103242447B (zh) 2016-04-27
RS55888B1 (sr) 2017-08-31
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AU2006252830A1 (en) 2006-12-07
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ME00261B (me) 2011-02-10
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US20080241163A1 (en) 2008-10-02
PT2460831T (pt) 2017-01-17
CY1118343T1 (el) 2017-06-28
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BRPI0611414B8 (pt) 2021-05-25
MX339015B (es) 2016-05-09
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PT1888113E (pt) 2014-09-04
BRPI0611414A2 (pt) 2010-09-08
DK2460831T3 (en) 2016-12-19
KR20080023317A (ko) 2008-03-13
IL187585A0 (en) 2008-04-13
MEP35408A (en) 2011-02-10
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HUE030701T2 (hu) 2017-05-29
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US20120009178A1 (en) 2012-01-12

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