ZA200107917B - Bicyclic heteroaromatic compounds useful as LH agonists. - Google Patents

Bicyclic heteroaromatic compounds useful as LH agonists.

Info

Publication number
ZA200107917B
ZA200107917B ZA200107917A ZA200107917A ZA200107917B ZA 200107917 B ZA200107917 B ZA 200107917B ZA 200107917 A ZA200107917 A ZA 200107917A ZA 200107917 A ZA200107917 A ZA 200107917A ZA 200107917 B ZA200107917 B ZA 200107917B
Authority
ZA
South Africa
Prior art keywords
agonists
compounds useful
heteroaromatic compounds
bicyclic heteroaromatic
bicyclic
Prior art date
Application number
ZA200107917A
Other languages
English (en)
Inventor
Gerrildina Geziena Gerritsma
Anton Egbert Peter Adang
Nicole Corine Renee Va Straten
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Publication of ZA200107917B publication Critical patent/ZA200107917B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Diabetes (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
ZA200107917A 1999-04-08 2001-09-26 Bicyclic heteroaromatic compounds useful as LH agonists. ZA200107917B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP99201152 1999-04-08

Publications (1)

Publication Number Publication Date
ZA200107917B true ZA200107917B (en) 2003-09-23

Family

ID=8240094

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200107917A ZA200107917B (en) 1999-04-08 2001-09-26 Bicyclic heteroaromatic compounds useful as LH agonists.

Country Status (30)

Country Link
US (2) US6569863B1 (enExample)
EP (1) EP1171443B1 (enExample)
JP (1) JP4854856B2 (enExample)
KR (1) KR100691546B1 (enExample)
CN (1) CN1177848C (enExample)
AR (1) AR028474A1 (enExample)
AT (1) ATE299507T1 (enExample)
AU (1) AU772258B2 (enExample)
BR (1) BRPI0009558B1 (enExample)
CA (1) CA2368834C (enExample)
CO (1) CO5160348A1 (enExample)
CZ (1) CZ300832B6 (enExample)
DE (1) DE60021262T2 (enExample)
DK (1) DK1171443T3 (enExample)
ES (1) ES2245304T3 (enExample)
HK (1) HK1041266B (enExample)
HU (1) HU229002B1 (enExample)
ID (1) ID30502A (enExample)
IL (2) IL145483A0 (enExample)
MX (1) MXPA01010144A (enExample)
NO (1) NO328826B1 (enExample)
NZ (1) NZ514445A (enExample)
PE (1) PE20010030A1 (enExample)
PL (1) PL219316B1 (enExample)
PT (1) PT1171443E (enExample)
RU (1) RU2248979C2 (enExample)
TR (1) TR200102839T2 (enExample)
TW (1) TW564247B (enExample)
WO (1) WO2000061586A1 (enExample)
ZA (1) ZA200107917B (enExample)

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EP1513516B1 (en) 2002-06-06 2008-12-03 Boehringer Ingelheim Pharmaceuticals Inc. SUBSTITUTED 3-AMINO-THIENO(2,3-b) PYRIDINE-2-CARBOXYLIC ACID AMIDE COMPOUNDS AND PROCESSES FOR PREPARING AND THEIR USES
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ATE418555T1 (de) 2003-04-09 2009-01-15 Biogen Idec Inc A2a-adenosinrezeptorantagonisten
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US7550485B2 (en) * 2003-10-14 2009-06-23 Wyeth Substituted N-heterocycle derivatives and methods of their use
WO2005039506A2 (en) * 2003-10-24 2005-05-06 Exelixis, Inc. P70s6 kinase modulators and method of use
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US7645881B2 (en) * 2004-07-22 2010-01-12 Ptc Therapeutics, Inc. Methods for treating hepatitis C
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AU2007254165A1 (en) * 2006-05-17 2007-11-29 Forschungsverbund Berlin E.V. Pyrimidine low molecular weight ligands for modulating hormone receptors
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TW200845978A (en) 2007-03-07 2008-12-01 Janssen Pharmaceutica Nv 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives
TW200900065A (en) 2007-03-07 2009-01-01 Janssen Pharmaceutica Nv 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives
NZ584152A (en) 2007-09-14 2011-11-25 Ortho Mcneil Janssen Pharm 1,3-disubstituted 4-(aryl-x-phenyl)-1h-pyridin-2-ones
US8722894B2 (en) * 2007-09-14 2014-05-13 Janssen Pharmaceuticals, Inc. 1,3-disubstituted-4-phenyl-1H-pyridin-2-ones
SI2203439T1 (sl) 2007-09-14 2011-05-31 Ortho Mcneil Janssen Pharm 1',3'-disubstituirani 4-fenil-3,4,5,6-tetrahidro-2H-1'H-(1,4')bipiridinil-2'-oni
PL2205608T3 (pl) * 2007-10-18 2013-09-30 Boehringer Ingelheim Int Sposób otrzymywania dihydrotieno[3,2-d]pirymidyn i związków pośrednich stosowanych w tym sposobie
RU2492170C9 (ru) 2007-11-14 2013-12-27 Орто-Макнейл-Янссен Фармасьютикалз, Инк. Имидазо[1,2-а]пиридиновые производные и их применение в качестве положительных аллостерических модуляторов рецепторов mglur2
AU2009289784B2 (en) 2008-09-02 2012-03-22 Addex Pharma S.A. 3-azabicyclo[3.1.0]hexyl derivatives as modulators of metabotropic glutamate receptors
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JP5852665B2 (ja) 2010-11-08 2016-02-03 ジヤンセン・フアーマシユーチカルズ・インコーポレーテツド １，２，４−トリアゾロ［４，３−ａ］ピリジン誘導体およびｍＧｌｕＲ２受容体のポジティブアロステリックモジュレーターとしてのそれらの使用
BR112014001274A2 (pt) 2011-07-18 2017-04-18 Arts Biologics As composto de hormônio luteinizante, e, composição farmacêutica
WO2013078126A1 (en) 2011-11-23 2013-05-30 Cancer Research Technology Limited Thienopyrimidine inhibitors of atypical protein kinase c
JO3368B1 (ar) 2013-06-04 2019-03-13 Janssen Pharmaceutica Nv مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2
JO3367B1 (ar) 2013-09-06 2019-03-13 Janssen Pharmaceutica Nv مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2
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Also Published As

Publication number Publication date
WO2000061586A1 (en) 2000-10-19
US6569863B1 (en) 2003-05-27
JP2002541259A (ja) 2002-12-03
CA2368834C (en) 2009-11-03
NO20014824D0 (no) 2001-10-04
CN1177848C (zh) 2004-12-01
ES2245304T3 (es) 2006-01-01
JP4854856B2 (ja) 2012-01-18
CZ20013605A3 (cs) 2002-03-13
DK1171443T3 (da) 2005-11-07
AU772258B2 (en) 2004-04-22
AR028474A1 (es) 2003-05-14
MXPA01010144A (es) 2002-04-24
PL219316B1 (pl) 2015-04-30
PT1171443E (pt) 2005-11-30
NO328826B1 (no) 2010-05-25
EP1171443A1 (en) 2002-01-16
RU2248979C2 (ru) 2005-03-27
US20030212081A1 (en) 2003-11-13
PE20010030A1 (es) 2001-01-27
DE60021262T2 (de) 2006-01-05
BR0009558A (pt) 2002-02-19
DE60021262D1 (de) 2005-08-18
KR20010103801A (ko) 2001-11-23
CA2368834A1 (en) 2000-10-19
HK1041266B (en) 2005-09-16
CO5160348A1 (es) 2002-05-30
TW564247B (en) 2003-12-01
BRPI0009558B1 (pt) 2016-10-25
HU229002B1 (en) 2013-07-29
TR200102839T2 (tr) 2002-04-22
HK1041266A1 (en) 2002-07-05
NZ514445A (en) 2003-07-25
KR100691546B1 (ko) 2007-03-12
IL145483A0 (en) 2002-06-30
PL350964A1 (en) 2003-02-24
EP1171443B1 (en) 2005-07-13
CN1349535A (zh) 2002-05-15
CZ300832B6 (cs) 2009-08-19
AU3816600A (en) 2000-11-14
HUP0200653A2 (en) 2002-06-29
ATE299507T1 (de) 2005-07-15
US6841553B2 (en) 2005-01-11
ID30502A (id) 2001-12-13
HUP0200653A3 (en) 2004-07-28
IL145483A (en) 2007-06-03
NO20014824L (no) 2001-10-04

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