BR112014001274A2 - composto de hormônio luteinizante, e, composição farmacêutica - Google Patents
composto de hormônio luteinizante, e, composição farmacêuticaInfo
- Publication number
- BR112014001274A2 BR112014001274A2 BR112014001274A BR112014001274A BR112014001274A2 BR 112014001274 A2 BR112014001274 A2 BR 112014001274A2 BR 112014001274 A BR112014001274 A BR 112014001274A BR 112014001274 A BR112014001274 A BR 112014001274A BR 112014001274 A2 BR112014001274 A2 BR 112014001274A2
- Authority
- BR
- Brazil
- Prior art keywords
- pharmaceutical composition
- luteinizing hormone
- hormone compound
- compound
- luteinizing
- Prior art date
Links
- 102000009151 Luteinizing Hormone Human genes 0.000 title 1
- 108010073521 Luteinizing Hormone Proteins 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 229940040129 luteinizing hormone Drugs 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/643—Albumins, e.g. HSA, BSA, ovalbumin or a Keyhole Limpet Hemocyanin [KHL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/644—Transferrin, e.g. a lactoferrin or ovotransferrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Reproductive Health (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP11174423 | 2011-07-18 | ||
EP11179410 | 2011-08-30 | ||
DKPA201170678 | 2011-12-07 | ||
US201261639268P | 2012-04-27 | 2012-04-27 | |
PCT/EP2012/063373 WO2013010840A2 (en) | 2011-07-18 | 2012-07-09 | Long acting biologically active luteinizing hormone (lh) compound |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112014001274A2 true BR112014001274A2 (pt) | 2017-04-18 |
Family
ID=47558539
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112014001274A BR112014001274A2 (pt) | 2011-07-18 | 2012-07-09 | composto de hormônio luteinizante, e, composição farmacêutica |
Country Status (10)
Country | Link |
---|---|
US (2) | US9353172B2 (pt) |
EP (1) | EP2734239A2 (pt) |
JP (1) | JP2014520869A (pt) |
KR (1) | KR20140053991A (pt) |
CN (1) | CN103930134B (pt) |
AU (1) | AU2012286048A1 (pt) |
BR (1) | BR112014001274A2 (pt) |
CA (1) | CA2842323A1 (pt) |
RU (1) | RU2014103185A (pt) |
WO (1) | WO2013010840A2 (pt) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
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US9493545B2 (en) | 2009-02-11 | 2016-11-15 | Albumedix A/S | Albumin variants and conjugates |
JP2013509170A (ja) | 2009-10-30 | 2013-03-14 | ノボザイムス バイオファーマ デーコー アクティーゼルスカブ | アルブミン変異体 |
CN102939304B (zh) | 2010-04-09 | 2017-04-19 | 阿尔布麦狄克斯公司 | 白蛋白衍生物和变体 |
EP2780364A2 (en) | 2011-11-18 | 2014-09-24 | Eleven Biotherapeutics, Inc. | Proteins with improved half-life and other properties |
CN104736559B (zh) | 2012-03-16 | 2022-04-08 | 阿尔布梅迪克斯医疗有限公司 | 白蛋白变体 |
CN105452290A (zh) | 2012-11-08 | 2016-03-30 | 诺维信生物制药丹麦公司 | 白蛋白变体 |
CN103509121B (zh) | 2012-11-22 | 2015-01-28 | 苏州康宁杰瑞生物科技有限公司 | 一种fsh融合蛋白及其制备方法和用途 |
CN103897064B (zh) * | 2013-11-29 | 2016-05-11 | 广州优联康医药科技有限公司 | 长效重组人绒促性素融合蛋白 |
CN103804498B (zh) * | 2013-11-29 | 2016-01-06 | 广州联康生物科技有限公司 | 长效重组绒促性素及其应用 |
CN104569441B (zh) * | 2015-01-19 | 2016-02-03 | 成都大熊猫繁育研究基地 | 大熊猫尿液促黄体素的酶联检测方法及其应用 |
CN107979973A (zh) * | 2015-05-04 | 2018-05-01 | 法国化学与生物科技实验室 | Fc融合蛋白质的转基因生产 |
WO2016178087A1 (en) * | 2015-05-04 | 2016-11-10 | Biosourcing Sa | Transgenic production of chorionic gonadotropin |
WO2017029407A1 (en) | 2015-08-20 | 2017-02-23 | Albumedix A/S | Albumin variants and conjugates |
RU2633079C2 (ru) * | 2016-06-21 | 2017-10-11 | Федеральное государственное бюджетное научное учреждение "Центр экспериментальной эмбриологии и репродуктивных биотехнологий" (ФГБНУ ЦЭЭРБ) | Фармацевтическая композиция с пролонгированным действием гонадотропинов для проведения индукции суперовуляции у самок млекопитающих |
WO2018102762A1 (en) | 2016-12-02 | 2018-06-07 | Avelas Biosciences, Inc. | Nerve labeling compositions and uses thereof |
CN107099501B (zh) * | 2017-05-27 | 2022-04-05 | 广东华农大资产经营有限公司 | 一种诱导幼龄灵长类动物获取性腺配子的方法和应用 |
CN112195194A (zh) * | 2020-10-30 | 2021-01-08 | 北京双鹭生物技术有限公司 | 重组人促卵泡激素及其制备方法 |
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US9493545B2 (en) * | 2009-02-11 | 2016-11-15 | Albumedix A/S | Albumin variants and conjugates |
JP2013509170A (ja) | 2009-10-30 | 2013-03-14 | ノボザイムス バイオファーマ デーコー アクティーゼルスカブ | アルブミン変異体 |
EP2513140B1 (en) | 2009-12-16 | 2015-11-04 | Novo Nordisk A/S | Double-acylated glp-1 derivatives |
-
2012
- 2012-07-09 CN CN201280045264.8A patent/CN103930134B/zh not_active Expired - Fee Related
- 2012-07-09 RU RU2014103185/10A patent/RU2014103185A/ru not_active Application Discontinuation
- 2012-07-09 WO PCT/EP2012/063373 patent/WO2013010840A2/en active Application Filing
- 2012-07-09 CA CA2842323A patent/CA2842323A1/en not_active Abandoned
- 2012-07-09 JP JP2014520603A patent/JP2014520869A/ja active Pending
- 2012-07-09 AU AU2012286048A patent/AU2012286048A1/en not_active Abandoned
- 2012-07-09 US US14/233,455 patent/US9353172B2/en not_active Expired - Fee Related
- 2012-07-09 KR KR1020147002105A patent/KR20140053991A/ko not_active Application Discontinuation
- 2012-07-09 EP EP12748400.4A patent/EP2734239A2/en not_active Withdrawn
- 2012-07-09 BR BR112014001274A patent/BR112014001274A2/pt not_active IP Right Cessation
-
2016
- 2016-05-28 US US15/168,001 patent/US20170000895A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20170000895A1 (en) | 2017-01-05 |
JP2014520869A (ja) | 2014-08-25 |
CN103930134A (zh) | 2014-07-16 |
CA2842323A1 (en) | 2013-01-24 |
AU2012286048A1 (en) | 2014-02-20 |
US20140228292A1 (en) | 2014-08-14 |
EP2734239A2 (en) | 2014-05-28 |
CN103930134B (zh) | 2016-12-21 |
KR20140053991A (ko) | 2014-05-08 |
WO2013010840A2 (en) | 2013-01-24 |
RU2014103185A (ru) | 2015-08-27 |
WO2013010840A3 (en) | 2013-04-11 |
US9353172B2 (en) | 2016-05-31 |
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