ATE418555T1 - A2a-adenosinrezeptorantagonisten - Google Patents

A2a-adenosinrezeptorantagonisten

Info

Publication number
ATE418555T1
ATE418555T1 AT04759359T AT04759359T ATE418555T1 AT E418555 T1 ATE418555 T1 AT E418555T1 AT 04759359 T AT04759359 T AT 04759359T AT 04759359 T AT04759359 T AT 04759359T AT E418555 T1 ATE418555 T1 AT E418555T1
Authority
AT
Austria
Prior art keywords
receptor antagonists
formula
adenosin
adenosin receptor
antagonists
Prior art date
Application number
AT04759359T
Other languages
English (en)
Inventor
Hairuo Peng
Gang Yao
Chi Vu
Russell C Petter
Gnanasambandam Kumaravel
Original Assignee
Biogen Idec Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Idec Inc filed Critical Biogen Idec Inc
Application granted granted Critical
Publication of ATE418555T1 publication Critical patent/ATE418555T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AT04759359T 2003-04-09 2004-04-09 A2a-adenosinrezeptorantagonisten ATE418555T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US46148403P 2003-04-09 2003-04-09

Publications (1)

Publication Number Publication Date
ATE418555T1 true ATE418555T1 (de) 2009-01-15

Family

ID=33299825

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04759359T ATE418555T1 (de) 2003-04-09 2004-04-09 A2a-adenosinrezeptorantagonisten

Country Status (5)

Country Link
US (1) US7834014B2 (de)
EP (1) EP1633756B1 (de)
AT (1) ATE418555T1 (de)
DE (1) DE602004018637D1 (de)
WO (1) WO2004092173A2 (de)

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WO2009036132A1 (en) 2007-09-11 2009-03-19 Abbott Laboratories Octahydro-pyrrolo[3,4-b]pyrrole n-oxides
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US20130045939A1 (en) 2010-03-19 2013-02-21 Catabasis Pharmaceuticals, Inc. Fatty acid macrolide derivatives and their uses
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WO2014101120A1 (en) * 2012-12-28 2014-07-03 Merck Sharp & Dohme Corp. Heterobicyclo-substituted-7-methoxy-[1,2,4]triazolo[1,5-c]quinazolin-5-amine compounds with a2a antagonist properties
SG11201901747VA (en) 2016-08-31 2019-03-28 Agios Pharmaceuticals Inc Inhibitors of cellular metabolic processes
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ES2919474T3 (es) * 2017-04-07 2022-07-26 Medshine Discovery Inc Derivado de [1,2,4]triazolo[1,5-c]pirimidina como inhibidor del receptor A2A
CN109535161B (zh) * 2017-09-22 2021-09-03 江苏恒瑞医药股份有限公司 三唑并嘧啶类衍生物、其制备方法及其在医药上的应用
US20190292188A1 (en) 2018-02-27 2019-09-26 Incyte Corporation Imidazopyrimidines and triazolopyrimidines as a2a / a2b inhibitors
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MA52940A (fr) 2018-05-18 2021-04-28 Incyte Corp Dérivés de pyrimidine fusionnés utilisés en tant qu'inhibiteurs de a2a/a2b
KR102633145B1 (ko) * 2018-06-26 2024-02-05 쩌지앙 빔그린 파머슈티컬스, 엘티디 A2a 수용체 길항제로서의 트리아졸로 트리아진 유도체
CN113166153B (zh) 2018-07-05 2024-11-01 因赛特公司 作为a2a/a2b抑制剂的稠合吡嗪衍生物
TWI829857B (zh) 2019-01-29 2024-01-21 美商英塞特公司 作為a2a / a2b抑制劑之吡唑并吡啶及三唑并吡啶
CN114901665B (zh) * 2019-12-26 2025-02-18 浙江春禾医药科技有限公司 三唑并三嗪衍生物在治疗疾病中的用途
US20240217978A1 (en) * 2021-04-23 2024-07-04 Chong Kun Dang Pharmaceutical Corp. COMPOUND AS ADENOSINE A2a RECEPTOR ANTAGONIST AND PHARMACEUTICAL COMPOSITION COMPRISING SAME
WO2023191400A1 (ko) * 2022-04-01 2023-10-05 에이치케이이노엔 주식회사 에틸 피페리딘 트리아졸로 트리아진 유도체, 이의 제조방법 및 이를 포함하는 암의 예방 또는 치료용 약학적 조성물

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Also Published As

Publication number Publication date
EP1633756B1 (de) 2008-12-24
EP1633756A2 (de) 2006-03-15
HK1083838A1 (en) 2006-07-14
US7834014B2 (en) 2010-11-16
WO2004092173A3 (en) 2004-12-09
WO2004092173A2 (en) 2004-10-28
US20070173505A1 (en) 2007-07-26
DE602004018637D1 (de) 2009-02-05

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