ZA200004016B - An iron-dextran compound for use as a component in a therapeutical composition for prophylaxis or treatment of iron-deficiency, a process for producing said iron-dextran compound and use of said compound for the preparation of a parenterally administrable therapeutical composition. - Google Patents

An iron-dextran compound for use as a component in a therapeutical composition for prophylaxis or treatment of iron-deficiency, a process for producing said iron-dextran compound and use of said compound for the preparation of a parenterally administrable therapeutical composition.

Info

Publication number
ZA200004016B
ZA200004016B ZA200004016A ZA200004016A ZA200004016B ZA 200004016 B ZA200004016 B ZA 200004016B ZA 200004016 A ZA200004016 A ZA 200004016A ZA 200004016 A ZA200004016 A ZA 200004016A ZA 200004016 B ZA200004016 B ZA 200004016B
Authority
ZA
South Africa
Prior art keywords
iron
compound
therapeutical composition
dextran
prophylaxis
Prior art date
Application number
ZA200004016A
Other languages
English (en)
Inventor
Hans Berg Andreasen
Lars Christensen
Original Assignee
Pharmacosmos Holding As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8093321&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200004016(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharmacosmos Holding As filed Critical Pharmacosmos Holding As
Publication of ZA200004016B publication Critical patent/ZA200004016B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Nutrition Science (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
ZA200004016A 1998-03-25 2000-08-07 An iron-dextran compound for use as a component in a therapeutical composition for prophylaxis or treatment of iron-deficiency, a process for producing said iron-dextran compound and use of said compound for the preparation of a parenterally administrable therapeutical composition. ZA200004016B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK199800420A DK172860B1 (da) 1998-03-25 1998-03-25 Jerndextranforbindelse til anvendelse som komponent i et terapeutisk middel til forebyggelse af eller behandling af jernman

Publications (1)

Publication Number Publication Date
ZA200004016B true ZA200004016B (en) 2001-07-25

Family

ID=8093321

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200004016A ZA200004016B (en) 1998-03-25 2000-08-07 An iron-dextran compound for use as a component in a therapeutical composition for prophylaxis or treatment of iron-deficiency, a process for producing said iron-dextran compound and use of said compound for the preparation of a parenterally administrable therapeutical composition.

Country Status (28)

Country Link
US (1) US6291440B1 (fr)
EP (1) EP1066056B2 (fr)
JP (1) JP4558198B2 (fr)
KR (1) KR100612071B1 (fr)
CN (1) CN1147322C (fr)
AR (1) AR015738A1 (fr)
AT (1) ATE220560T1 (fr)
AU (1) AU740432B2 (fr)
BR (1) BRPI9908914B8 (fr)
CA (1) CA2322633C (fr)
CZ (1) CZ300823B6 (fr)
DE (1) DE69902154T3 (fr)
DK (2) DK172860B1 (fr)
EA (1) EA003427B1 (fr)
ES (1) ES2180279T5 (fr)
HK (1) HK1033426A1 (fr)
HU (1) HU228483B1 (fr)
ID (1) ID26778A (fr)
NO (1) NO329591B1 (fr)
NZ (1) NZ505983A (fr)
PL (1) PL195582B1 (fr)
PT (1) PT1066056E (fr)
SI (1) SI1066056T2 (fr)
SK (1) SK284499B6 (fr)
TR (1) TR200002733T2 (fr)
UA (1) UA70939C2 (fr)
WO (1) WO1999048533A1 (fr)
ZA (1) ZA200004016B (fr)

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Publication number Priority date Publication date Assignee Title
DK173138B1 (da) 1998-11-20 2000-02-07 Pharmacosmos Holding As Fremgangsmåde til fremstilling af en jerndextranforbindelse, jerndextranforbindelse fremstillet efter fremgangsmåden, farma
WO2000061191A2 (fr) * 1999-04-09 2000-10-19 Advanced Magnetics, Inc. Oxydes de fer colloidaux thermostables recouverts de carbohydrates reduits et des derives de carbohydrates
US7871597B2 (en) 1999-04-09 2011-01-18 Amag Pharmaceuticals, Inc. Polyol and polyether iron oxide complexes as pharmacological and/or MRI contrast agents
KR20020003344A (ko) * 2001-12-17 2002-01-12 유형선 철분 보급제 경구 투여 제제 조성물
EA006720B1 (ru) * 2002-04-09 2006-04-28 Фармакосмос Холдинг А/С Железосодержащие соединения декстрина для лечения железодефицитной анемии
DE10249552A1 (de) 2002-10-23 2004-05-13 Vifor (International) Ag Wasserlösliche Eisen-Kohlenhydrat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel
US20060116349A1 (en) * 2003-03-14 2006-06-01 Luitpold Pharmaceuticals, Inc. Methods and compositions for administration of iron for the treatment of restless leg syndrome
DE102004031181A1 (de) * 2004-06-28 2006-01-19 Vifor (International) Ag Phosphatadsorbens
ITMO20050056A1 (it) 2005-03-15 2006-09-16 Biofer Spa Processo per la preparazione di complessi del ferro trivalente con zuccheri mono-, di- e polisaccaridi.
EP1757299A1 (fr) 2005-08-25 2007-02-28 Vifor (International) Ag Complexes de fer III pour traiter les manques de fer en patients avec la maladie intestinale inflammatoire
KR20080082674A (ko) 2006-01-06 2008-09-11 루이트폴드 파머수티컬스, 인코퍼레이티드 철을 투여하기 위한 방법 및 조성물
EP1947120A1 (fr) * 2007-01-19 2008-07-23 Vifor (International) Ag Liaisons complexes d'hydrate de carbone de fer
EP1997833A1 (fr) * 2007-05-29 2008-12-03 Vifor (International) Ag Complexes fer-dérivé d'hydrate de carbone hydrosolubles, leur fabrication et médicaments contenants ces complexes
CN101585887B (zh) * 2008-05-22 2011-12-14 中国科学院过程工程研究所 应用纳滤技术对右旋糖酐铁络合物水溶液进行脱盐和浓缩的方法
SI2411053T1 (sl) * 2009-03-25 2017-04-26 Pharmacosmos Holding A/S Stabilna spojina železovega oligosaharida
CN101967205B (zh) * 2010-10-12 2013-04-17 滨州学院 一种β-葡聚糖铁复合物及其制备方法
EP2537866A1 (fr) * 2011-06-21 2012-12-26 Serumwerk Bernburg AG Dérivés d'amidon hydroxyéthyle, procédé de fabrication de ceux-ci et leurs utilisations thérapeutiques
PL398814A1 (pl) 2012-04-16 2013-10-28 Uniwersytet Jagiellonski Zastosowanie pochodnych dekstranu do przeciwdzialania lub leczenia niedokrwistosci
WO2015198304A1 (fr) 2014-06-22 2015-12-30 Dexcel Pharma Technologies Ltd. Compositions pharmaceutiques comprenant du citrate ferrique et procédés de fabrication de celles-ci
CA2965722C (fr) * 2014-10-27 2023-02-14 Pharmacosmos Holding A/S Traitement ou prevention de l'anemie chez des mammiferes non humains gravides
WO2019048674A1 (fr) 2017-09-11 2019-03-14 Pharmacosmos Holding A/S Composés complexes de fer à usage thérapeutique
CN109646454A (zh) * 2018-12-29 2019-04-19 博瑞生物医药(苏州)股份有限公司 异麦芽糖酐铁1000的制备方法
CN110183548B (zh) * 2019-06-28 2021-05-18 瑞普(天津)生物药业有限公司 一种低分子葡聚糖铁的制备方法及其应用
WO2023012242A1 (fr) 2021-08-03 2023-02-09 Pharmacosmos Holding A/S Composés de complexe de fer pour une utilisation sous-cutanée dans la thérapie de la carence en fer chez les animaux de compagnie

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK117730A (fr)
USRE24642E (en) 1959-04-28 Therapeutic preparations of iron
US2885393A (en) 1956-02-24 1959-05-05 R K Laros Company Dextran-iron complex and process for making same
US3093545A (en) 1960-08-29 1963-06-11 Armour Pharma Therapeutic iron-dextran preparations
US3234209A (en) * 1963-09-13 1966-02-08 Chemicals Inc Process for making iron hydrogenated dextran
DE1293144B (de) * 1964-11-04 1969-04-24 Hausmann Ag Labor Verfahren zur Herstellung von Komplexverbindungen des Eisens mit Sorbit, Gluconsaeure und einem Oligosaccharid
GB1183940A (en) 1966-10-22 1970-03-11 Fisons Pharmaceuticals Ltd Ferric Hydroxide Complexes
GB1200902A (en) 1967-05-13 1970-08-05 Fisons Pharmaceuticals Ltd Iron-dextran complexes
CH507993A (de) 1967-07-13 1971-05-31 Kutnowskie Zakl Farma Verfahren zur Herstellung von Eisen(III)-komplexverbindungen mit hydriertem Dextran
DK129353B (da) 1968-04-29 1974-09-30 Fisons Pharmaceuticals Ltd Analogifremgangsmåde til fremstilling af et ferrihydroxid-dextranderivatkompleks eller en opløsning deraf.
US3697502A (en) 1969-11-03 1972-10-10 Christensen Henry M Method of making iron dextran-preparations
GB1562913A (en) * 1976-06-16 1980-03-19 Fisons Ltd Fractionating fluid mixtures of dextrans
DE3422249A1 (de) * 1984-06-15 1985-12-19 Pfeifer & Langen, 5000 Köln Wasserloesliches eisendextran und verfahren zu seiner herstellung
US4827945A (en) 1986-07-03 1989-05-09 Advanced Magnetics, Incorporated Biologically degradable superparamagnetic materials for use in clinical applications
US5102652A (en) * 1986-07-03 1992-04-07 Advanced Magnetics Inc. Low molecular weight carbohydrates as additives to stabilize metal oxide compositions
IT1263831B (it) * 1993-01-29 1996-09-04 Paolo Chiesi Complessi di inclusione multicomponente ad elevata solubilita' costituiti da un farmaco di tipo basico, un acido ed una ciclodestrina
RU2093577C1 (ru) * 1993-11-04 1997-10-20 Государственный институт кровезаменителей и медицинских препаратов Способ получения декстрана
GB9402029D0 (en) * 1994-02-03 1994-03-30 Smithkline Beecham Plc Novel formulation
US5624668A (en) * 1995-09-29 1997-04-29 Luitpold Pharmaceuticals, Inc. Iron dextran formulations

Also Published As

Publication number Publication date
WO1999048533A1 (fr) 1999-09-30
ES2180279T3 (es) 2003-02-01
JP2002507582A (ja) 2002-03-12
NO20004151D0 (no) 2000-08-18
PL343164A1 (en) 2001-07-30
BRPI9908914B1 (pt) 2012-06-12
TR200002733T2 (tr) 2000-12-21
PL195582B1 (pl) 2007-10-31
CN1293577A (zh) 2001-05-02
BRPI9908914B8 (pt) 2021-07-06
SI1066056T2 (sl) 2009-04-30
AU2827399A (en) 1999-10-18
BRPI9908914A (pt) 2000-11-21
DK172860B1 (da) 1999-08-16
HUP0101189A2 (hu) 2001-08-28
HK1033426A1 (en) 2001-08-31
ID26778A (id) 2001-02-08
KR20010034641A (ko) 2001-04-25
NO20004151L (no) 2000-08-18
EA200000981A1 (ru) 2001-02-26
PT1066056E (pt) 2002-12-31
AU740432B2 (en) 2001-11-01
EP1066056B1 (fr) 2002-07-17
CZ300823B6 (cs) 2009-08-19
DK1066056T4 (da) 2009-04-14
EA003427B1 (ru) 2003-04-24
HUP0101189A3 (en) 2003-12-29
CN1147322C (zh) 2004-04-28
CZ20003535A3 (cs) 2001-04-11
DE69902154T2 (de) 2003-03-06
ATE220560T1 (de) 2002-08-15
CA2322633C (fr) 2009-01-27
US6291440B1 (en) 2001-09-18
AR015738A1 (es) 2001-05-16
CA2322633A1 (fr) 1999-09-30
NO329591B1 (no) 2010-11-15
SK284499B6 (sk) 2005-05-05
DE69902154D1 (de) 2002-08-22
UA70939C2 (uk) 2004-11-15
NZ505983A (en) 2002-11-26
EP1066056B2 (fr) 2008-12-10
HU228483B1 (en) 2013-03-28
DE69902154T3 (de) 2009-07-09
JP4558198B2 (ja) 2010-10-06
SI1066056T1 (en) 2002-12-31
DK1066056T3 (da) 2002-10-14
SK14092000A3 (sk) 2001-04-09
EP1066056A1 (fr) 2001-01-10
ES2180279T5 (es) 2009-05-05
KR100612071B1 (ko) 2006-08-11
DK42099A (da) 1999-08-16

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