WO2010102758A3 - Cétoénols à substitution halogénoalkylméthylèneoxy-phényle - Google Patents
Cétoénols à substitution halogénoalkylméthylèneoxy-phényle Download PDFInfo
- Publication number
- WO2010102758A3 WO2010102758A3 PCT/EP2010/001392 EP2010001392W WO2010102758A3 WO 2010102758 A3 WO2010102758 A3 WO 2010102758A3 EP 2010001392 W EP2010001392 W EP 2010001392W WO 2010102758 A3 WO2010102758 A3 WO 2010102758A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- halogenalkylmethylenoxy
- phenyl
- substituted ketoenols
- contain
- producing
- Prior art date
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/72—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms
- C07C235/76—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
- C07C235/78—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton the carbon skeleton containing rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/36—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/36—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom five-membered rings
- A01N43/38—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom five-membered rings condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom
- A01N47/06—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom containing —O—CO—O— groups; Thio analogues thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/734—Ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
- C07D207/38—2-Pyrrolones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/54—Spiro-condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/94—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/10—Spiro-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Dentistry (AREA)
- Environmental Sciences (AREA)
- Engineering & Computer Science (AREA)
- Plant Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Health & Medical Sciences (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Furan Compounds (AREA)
- Pyrane Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Priority Applications (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MX2013011965A MX338802B (es) | 2009-03-11 | 2010-03-05 | Cetoenoles sustituidos con haloalquilmetilenoxi-fenilo. |
CN201080011864.3A CN102348684B (zh) | 2009-03-11 | 2010-03-05 | 被卤代烷基亚甲基氧基苯基取代的酮烯醇 |
ES10708924.5T ES2632567T3 (es) | 2009-03-11 | 2010-03-05 | Cetoenoles sustituidos con haloalquilmetilenoxi-fenilo |
MX2011009188A MX2011009188A (es) | 2009-03-11 | 2010-03-05 | Cetoenoles sustituidos con haloalquilmetilenoxi-fenilo. |
BRPI1008949-7A BRPI1008949B1 (pt) | 2009-03-11 | 2010-03-05 | Cetoenóis haloalquilmetilenóxi-fenil-substituídos e seu uso, composição, seu uso e seu método de produção, métodos para combate de pestes animais e/ou crescimento de plantas indesejadas |
EA201190190A EA024266B1 (ru) | 2009-03-11 | 2010-03-05 | Кетоенолы, замещенные галоидалкилметиленоксифенилом, и их применение |
CA2754847A CA2754847C (fr) | 2009-03-11 | 2010-03-05 | Cetoenols a substitution halogenoalkylmethyleneoxy-phenyle |
KR1020117023789A KR101703633B1 (ko) | 2009-03-11 | 2010-03-05 | 할로겐알킬메틸렌옥시페닐-치환된 케토에놀 |
AU2010223535A AU2010223535B2 (en) | 2009-03-11 | 2010-03-05 | Halogenalkylmethylenoxy-phenyl-substituted ketoenols |
JP2011553331A JP5840955B2 (ja) | 2009-03-11 | 2010-03-05 | ハロゲンアルキルメチレンオキシフェニル置換ケトエノール類 |
EP10708924.5A EP2406216B1 (fr) | 2009-03-11 | 2010-03-05 | Kétoénoles substitués par halogenalkylméthylenoxy-phényl |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP09154888.3 | 2009-03-11 | ||
EP09154888 | 2009-03-11 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2010102758A2 WO2010102758A2 (fr) | 2010-09-16 |
WO2010102758A3 true WO2010102758A3 (fr) | 2011-01-20 |
Family
ID=41228842
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2010/001392 WO2010102758A2 (fr) | 2009-03-11 | 2010-03-05 | Cétoénols à substitution halogénoalkylméthylèneoxy-phényle |
Country Status (15)
Country | Link |
---|---|
US (2) | US8518985B2 (fr) |
EP (2) | EP2406216B1 (fr) |
JP (1) | JP5840955B2 (fr) |
KR (1) | KR101703633B1 (fr) |
CN (2) | CN103641709B (fr) |
AR (1) | AR075848A1 (fr) |
AU (1) | AU2010223535B2 (fr) |
BR (1) | BRPI1008949B1 (fr) |
CA (1) | CA2754847C (fr) |
EA (1) | EA024266B1 (fr) |
ES (1) | ES2632567T3 (fr) |
HU (1) | HUE035166T2 (fr) |
MX (2) | MX338802B (fr) |
PL (1) | PL2406216T3 (fr) |
WO (1) | WO2010102758A2 (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9204640B2 (en) | 2011-03-01 | 2015-12-08 | Bayer Intellectual Property Gmbh | 2-acyloxy-pyrrolin-4-ones |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUE035166T2 (en) | 2009-03-11 | 2018-05-02 | Bayer Ip Gmbh | Halogenalkylmethyleneoxyphenyl substituted ketoenols |
MX2012002299A (es) * | 2009-09-09 | 2012-03-29 | Bayer Cropscience Ag | Uso de cetoenoles ciclicos contra bacterias fitopatogenas. |
JP6151917B2 (ja) | 2010-02-10 | 2017-06-21 | バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングBayer Intellectual Property GmbH | スピロヘテロ環置換テトラミン酸誘導体 |
BR112012020084B1 (pt) | 2010-02-10 | 2017-12-19 | Bayer Intellectual Property Gmbh | A process for the preparation of pesticides and / or herbicides and / or fungi and / or fungi and / or fungicides and / or fungicides and / or fungicides and / or fungicides. METHOD FOR INCREASING THE ACTION OF PESTICIDES AND / OR HERBICIDES AND / OR FUNGICIDES COMPREHENDING SUCH COMPOUNDS |
DE102010008644A1 (de) | 2010-02-15 | 2011-08-18 | Bayer Schering Pharma Aktiengesellschaft, 13353 | Zyklische Ketoenole zur Therapie |
CN102939007B (zh) | 2010-04-20 | 2015-09-02 | 拜耳知识产权有限责任公司 | 基于螺杂环取代的特特拉姆酸衍生物的具有改善活性的杀虫和/或除草组合物 |
BR112013010810A2 (pt) * | 2010-11-02 | 2016-08-09 | Bayer Ip Gmbh | derivados de fenil-substituído bicicloocteno-1, 3-diona. |
MX2013008361A (es) | 2011-01-25 | 2013-08-27 | Bayer Ip Gmbh | Procedimiento para la preparacion de derivados 1-h-pirrolidin-2,4-diona. |
DE102011011040A1 (de) | 2011-02-08 | 2012-08-09 | Bayer Pharma Aktiengesellschaft | (5s,8s)-3-(4'-Chlor-3'-fluor-4-methylbiphenyl-3-yl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]dec-3-en-2-on (Verbindung A) zur Therapie |
WO2012110519A1 (fr) | 2011-02-17 | 2012-08-23 | Bayer Cropscience Ag | 3-(biphényle-3-yl)-8,8-difluoro-4-hydroxy-1-azaspiro[4,5]dec-3-en-2-ones substituées pour la thérapie et des cétoénols spirocycliques substitués par des halogènes |
DE102011080405A1 (de) | 2011-08-04 | 2013-02-07 | Bayer Pharma AG | Substituierte 3-(Biphenyl-3-yl)-8,8-difluor-4-hydroxy-1-azaspiro[4.5]dec-3-en-2-one zur Therapie |
BR112013023213A8 (pt) | 2011-03-11 | 2018-01-23 | Bayer Ip Gmbh | derivados da 1h-pirrolidina-2,4-diona espirocíclica cis-alcoxi-substituídos |
JP5878816B2 (ja) * | 2011-05-12 | 2016-03-08 | 住友化学株式会社 | 粒子の製造方法 |
DE102011080406A1 (de) | 2011-08-04 | 2013-02-07 | Bayer Pharma AG | Substituierte 3-(Biphenyl-3-yl)-4-hydroxy-8-methoxy-1-azaspiro8[4.5]dec-3-en-2-one |
EP2986593B1 (fr) | 2013-04-19 | 2017-07-19 | Syngenta Limited | Composés de 2-(phényl substitué)-cyclopentane-1,3-dione présentant une activité herbicide, et leurs dérivés |
GB201310047D0 (en) | 2013-06-05 | 2013-07-17 | Syngenta Ltd | Compounds |
RU2608369C2 (ru) * | 2014-03-31 | 2017-01-18 | Кей Эм Ю Ко., Лтд. | Стыковочная конструкция внешних стеновых материалов |
CN107690281B (zh) | 2014-10-06 | 2020-11-17 | 弗特克斯药品有限公司 | 囊性纤维化跨膜转导调节因子调节剂 |
CN112159321A (zh) * | 2015-06-22 | 2021-01-01 | 拜耳作物科学股份公司 | 新的炔基取代的3-苯基吡咯烷-2,4-二酮及其作为除草剂的用途 |
CN108473402A (zh) | 2016-01-15 | 2018-08-31 | 拜耳作物科学股份公司 | 制备取代的2-芳基乙醇的方法 |
PL3436446T3 (pl) | 2016-03-31 | 2023-09-11 | Vertex Pharmaceuticals Incorporated | Modulatory mukowiscydozowego przezbłonowego regulatora przewodnictwa |
CN109311903A (zh) * | 2016-04-14 | 2019-02-05 | 拜耳作物科学股份公司 | 具有除草作用的环状3-苯基特特拉姆酸衍生物 |
DK3519401T3 (da) | 2016-09-30 | 2021-11-22 | Vertex Pharma | Modulator af cystisk fibrosetransmembrankonduktansregulator, farmaceutiske sammensætninger, fremgangsmåder til behandling og fremgangsmåde til fremstilling af modulatoren |
IL294237A (en) | 2016-12-09 | 2022-08-01 | Vertex Pharma | Modulatory modulation of transmembrane conductance in cystic fibrosis, pharmaceutical preparations, treatment methods, and a process for creating the modulator |
AU2018279646B2 (en) | 2017-06-08 | 2023-04-06 | Vertex Pharmaceuticals Incorporated | Methods of treatment for cystic fibrosis |
CA3069226A1 (fr) | 2017-07-17 | 2019-01-24 | Vertex Pharmaceuticals Incorporated | Methodes de traitement de la fibrose kystique |
AR112467A1 (es) | 2017-08-02 | 2019-10-30 | Vertex Pharma | Procesos para preparar compuestos |
IL273831B1 (en) | 2017-10-19 | 2024-06-01 | Vertex Pharma | Crystal forms and preparations of CFTR modulators |
JP7245834B2 (ja) | 2017-12-08 | 2023-03-24 | バーテックス ファーマシューティカルズ インコーポレイテッド | 嚢胞性線維症膜コンダクタンス制御因子のモジュレーターを作成するためのプロセス |
TWI810243B (zh) | 2018-02-05 | 2023-08-01 | 美商維泰克斯製藥公司 | 用於治療囊腫纖化症之醫藥組合物 |
WO2019197617A1 (fr) | 2018-04-13 | 2019-10-17 | Bayer Cropscience Aktiengesellschaft | Utilisation de dérivés d'acide tétramique pour lutter contre des bioagresseurs animaux par arrosage, pulvérisation, traitement de trou de plantation ou application sur raie. |
WO2019200246A1 (fr) | 2018-04-13 | 2019-10-17 | Alexander Russell Abela | Modulateurs du régulateur de la conductance transmembranaire de la fibrose kystique, compositions pharmaceutiques, procédés de traitement et procédé de fabrication du modulateur |
WO2019197652A1 (fr) | 2018-04-13 | 2019-10-17 | Bayer Aktiengesellschaft | Formulation solide de mélanges insecticides |
WO2019197612A1 (fr) | 2018-04-13 | 2019-10-17 | Bayer Cropscience Aktiengesellschaft | Utilisation de dérivés d'acide tétramique pour lutter contre les bioagresseurs animaux par arrosage ou pulvérisation |
CN112312768A (zh) | 2018-04-13 | 2021-02-02 | 拜耳作物科学股份公司 | 特特拉姆酸衍生物用于防治特定昆虫的用途 |
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- 2010-03-05 WO PCT/EP2010/001392 patent/WO2010102758A2/fr active Application Filing
- 2010-03-05 EP EP10708924.5A patent/EP2406216B1/fr not_active Not-in-force
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CN102348684A (zh) | 2012-02-08 |
US8518985B2 (en) | 2013-08-27 |
US9045390B2 (en) | 2015-06-02 |
KR101703633B1 (ko) | 2017-02-07 |
EP2406216B1 (fr) | 2017-04-19 |
BRPI1008949A8 (pt) | 2016-05-03 |
MX2011009188A (es) | 2011-09-26 |
HUE035166T2 (en) | 2018-05-02 |
CN103641709A (zh) | 2014-03-19 |
CN102348684B (zh) | 2014-11-12 |
EA024266B1 (ru) | 2016-09-30 |
JP2012520242A (ja) | 2012-09-06 |
AU2010223535A1 (en) | 2011-09-22 |
AU2010223535B2 (en) | 2015-09-10 |
US20140213813A9 (en) | 2014-07-31 |
MX338802B (es) | 2016-05-02 |
KR20110132591A (ko) | 2011-12-08 |
WO2010102758A2 (fr) | 2010-09-16 |
ES2632567T3 (es) | 2017-09-14 |
PL2406216T3 (pl) | 2017-09-29 |
US20140031577A1 (en) | 2014-01-30 |
AR075848A1 (es) | 2011-05-04 |
BRPI1008949B1 (pt) | 2018-07-10 |
CA2754847C (fr) | 2017-07-11 |
CA2754847A1 (fr) | 2010-09-16 |
JP5840955B2 (ja) | 2016-01-06 |
BRPI1008949A2 (pt) | 2015-09-01 |
US20100311593A1 (en) | 2010-12-09 |
CN103641709B (zh) | 2017-08-25 |
EP2406216A2 (fr) | 2012-01-18 |
EA201190190A1 (ru) | 2012-02-28 |
EP3153503A1 (fr) | 2017-04-12 |
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