MX338802B - Cetoenoles sustituidos con haloalquilmetilenoxi-fenilo. - Google Patents
Cetoenoles sustituidos con haloalquilmetilenoxi-fenilo.Info
- Publication number
- MX338802B MX338802B MX2013011965A MX2013011965A MX338802B MX 338802 B MX338802 B MX 338802B MX 2013011965 A MX2013011965 A MX 2013011965A MX 2013011965 A MX2013011965 A MX 2013011965A MX 338802 B MX338802 B MX 338802B
- Authority
- MX
- Mexico
- Prior art keywords
- halogenalkylmethylenoxy
- phenyl
- substituted ketoenols
- contain
- producing
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 abstract 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 abstract 1
- 241000607479 Yersinia pestis Species 0.000 abstract 1
- 230000000895 acaricidal effect Effects 0.000 abstract 1
- 239000000642 acaricide Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 244000038559 crop plants Species 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000003623 enhancer Substances 0.000 abstract 1
- 230000002363 herbicidal effect Effects 0.000 abstract 1
- 239000004009 herbicide Substances 0.000 abstract 1
- 239000002917 insecticide Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 230000035515 penetration Effects 0.000 abstract 1
- 150000004714 phosphonium salts Chemical class 0.000 abstract 1
- 230000008635 plant growth Effects 0.000 abstract 1
- 239000011814 protection agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/72—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms
- C07C235/76—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
- C07C235/78—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton the carbon skeleton containing rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/36—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom five-membered rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/36—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom five-membered rings
- A01N43/38—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom five-membered rings condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom
- A01N47/06—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom containing —O—CO—O— groups; Thio analogues thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/734—Ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
- C07D207/38—2-Pyrrolones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/54—Spiro-condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/94—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/10—Spiro-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Dentistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Plant Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Indole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Furan Compounds (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La presente invención se refiere a nuevos compuestos de la fórmula (I), en la que W, X, Y, Z y CKE tiene los significados indicados anteriormente, a varios procedimientos y productos intermedios para su preparación y a su uso como plaguicidas y/o herbicidas. También se refiere la invención a agentes herbicidas selectivos que contienen, por una parte, cetoenoles sustituidos con haloalquilmetilenoxi-fenilo y, por otra parte, compuestos que mejoran la tolerancia por parte de las plantas de cultivo. La presente invención se refiere, además, al aumento del efecto de agentes fitoprotectores que contienen, en particular, cetoenoles sustituidos con haloalquilmetilenoxi-fenilo, mediante la adición de sales de amonio o de fosfonio y, dado el caso, promotores de la penetración, a los agentes correspondientes, a procedimientos para su preparación y a su uso en fitoprotección como insecticidas y/o acaricidas y/o para inhibir la vegetación no deseada.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09154888 | 2009-03-11 | ||
| PCT/EP2010/001392 WO2010102758A2 (de) | 2009-03-11 | 2010-03-05 | Halogenalkylmethylenoxy-phenyl-substituierte ketoenole |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX338802B true MX338802B (es) | 2016-05-02 |
Family
ID=41228842
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2013011965A MX338802B (es) | 2009-03-11 | 2010-03-05 | Cetoenoles sustituidos con haloalquilmetilenoxi-fenilo. |
| MX2011009188A MX2011009188A (es) | 2009-03-11 | 2010-03-05 | Cetoenoles sustituidos con haloalquilmetilenoxi-fenilo. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2011009188A MX2011009188A (es) | 2009-03-11 | 2010-03-05 | Cetoenoles sustituidos con haloalquilmetilenoxi-fenilo. |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US8518985B2 (es) |
| EP (2) | EP3153503A1 (es) |
| JP (1) | JP5840955B2 (es) |
| KR (1) | KR101703633B1 (es) |
| CN (2) | CN103641709B (es) |
| AR (1) | AR075848A1 (es) |
| AU (1) | AU2010223535B2 (es) |
| BR (1) | BRPI1008949B1 (es) |
| CA (1) | CA2754847C (es) |
| EA (1) | EA024266B1 (es) |
| ES (1) | ES2632567T3 (es) |
| HU (1) | HUE035166T2 (es) |
| MX (2) | MX338802B (es) |
| PL (1) | PL2406216T3 (es) |
| WO (1) | WO2010102758A2 (es) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2632567T3 (es) | 2009-03-11 | 2017-09-14 | Bayer Intellectual Property Gmbh | Cetoenoles sustituidos con haloalquilmetilenoxi-fenilo |
| WO2011029536A2 (de) * | 2009-09-09 | 2011-03-17 | Bayer Cropscience Ag | Verwendung von cyclischen ketoenolen gegen pflanzenpathogene bakterien |
| ES2545113T3 (es) | 2010-02-10 | 2015-09-08 | Bayer Intellectual Property Gmbh | Derivados de ácido tetrámico sustituidos de manera espiroheterocíclica |
| JP5892949B2 (ja) | 2010-02-10 | 2016-03-23 | バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングBayer Intellectual Property GmbH | ビフェニル置換環状ケトエノール類 |
| DE102010008644A1 (de) | 2010-02-15 | 2011-08-18 | Bayer Schering Pharma Aktiengesellschaft, 13353 | Zyklische Ketoenole zur Therapie |
| BR112012027044A8 (pt) | 2010-04-20 | 2017-10-10 | Bayer Ip Gmbh | Composição inseticida e/ou herbicida tendo a atividade melhorada com base nos derivados de ácido tetrâmico substituídos por espiroheterocíclicos. |
| CN103339096A (zh) * | 2010-11-02 | 2013-10-02 | 拜耳知识产权有限责任公司 | 苯基取代的二环辛烷-1,3-二酮衍生物 |
| ES2689149T3 (es) | 2011-01-25 | 2018-11-08 | Bayer Cropscience Ag | Procedimiento para la preparación de derivados de 1-H-pirrolidin-2,4-diona |
| DE102011011040A1 (de) | 2011-02-08 | 2012-08-09 | Bayer Pharma Aktiengesellschaft | (5s,8s)-3-(4'-Chlor-3'-fluor-4-methylbiphenyl-3-yl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]dec-3-en-2-on (Verbindung A) zur Therapie |
| DE102011080405A1 (de) | 2011-08-04 | 2013-02-07 | Bayer Pharma AG | Substituierte 3-(Biphenyl-3-yl)-8,8-difluor-4-hydroxy-1-azaspiro[4.5]dec-3-en-2-one zur Therapie |
| US8946124B2 (en) | 2011-02-17 | 2015-02-03 | Bayer Intellectual Property Gmbh | Substituted 3-(biphenyl-3-yl)-8,8-difluoro-4-hydroxy-1-azaspiro[4.5]dec-3-en-2-ones for therapy and halogen-substituted spirocyclic ketoenols |
| KR101789527B1 (ko) * | 2011-03-01 | 2017-10-25 | 바이엘 인텔렉쳐 프로퍼티 게엠베하 | 2-아실옥시피롤린-4-온 |
| KR101925162B1 (ko) | 2011-03-11 | 2018-12-04 | 바이엘 인텔렉쳐 프로퍼티 게엠베하 | 시스-알콕시-치환된 스피로시클릭 1-h-피롤리딘-2,4-디온 유도체 |
| JP5878816B2 (ja) * | 2011-05-12 | 2016-03-08 | 住友化学株式会社 | 粒子の製造方法 |
| DE102011080406A1 (de) | 2011-08-04 | 2013-02-07 | Bayer Pharma AG | Substituierte 3-(Biphenyl-3-yl)-4-hydroxy-8-methoxy-1-azaspiro8[4.5]dec-3-en-2-one |
| CA2909371C (en) | 2013-04-19 | 2021-11-16 | Syngenta Limited | Herbicidally active 2-(substituted-phenyl)-cyclopentane-1,3-dione compounds and derivatives thereof |
| GB201310047D0 (en) | 2013-06-05 | 2013-07-17 | Syngenta Ltd | Compounds |
| RU2608369C2 (ru) * | 2014-03-31 | 2017-01-18 | Кей Эм Ю Ко., Лтд. | Стыковочная конструкция внешних стеновых материалов |
| EP3798214B1 (en) | 2014-10-06 | 2022-09-14 | Vertex Pharmaceuticals Incorporated | Modulators of cystic fibrosis transmembrane conductance regulator |
| UA120656C2 (uk) * | 2015-06-22 | 2020-01-10 | Баєр Кропсаєнс Акціенгезельшафт | Нові алкінілзаміщені 3-фенілпіролідин-2,4-діони та їх застосування як гербіцидів |
| MX2018008718A (es) | 2016-01-15 | 2018-09-21 | Bayer Cropscience Ag | Metodo para la preparacion de 2-aril-etanoles sustituido. |
| EP3436446B1 (en) | 2016-03-31 | 2023-06-07 | Vertex Pharmaceuticals Incorporated | Modulators of cystic fibrosis transmembrane conductance regulator |
| EA201892187A1 (ru) * | 2016-04-14 | 2019-05-31 | Байер Кропсайенс Акциенгезельшафт | Аннелированные производные 3-фенилтетрамовой кислоты с гербицидным действием |
| SG10201913595YA (en) | 2016-09-30 | 2020-02-27 | Vertex Pharma | Modulator of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulator |
| MA49235B1 (fr) | 2016-12-09 | 2021-02-26 | Vertex Pharma | Modulateur de régulateur de conductance transmembranaire de fibrose kystique, compositions pharmaceutiques, procédés de traitement et procédé de fabrication du modulateur |
| EP3634402B1 (en) | 2017-06-08 | 2026-01-21 | Vertex Pharmaceuticals Incorporated | Methods of treatment for cystic fibrosis |
| BR112020000941A2 (pt) | 2017-07-17 | 2020-07-21 | Vertex Pharmaceuticals Incorporated | métodos de tratamento para fibrose cística |
| TWI799435B (zh) | 2017-08-02 | 2023-04-21 | 美商維泰克斯製藥公司 | 製備化合物之製程 |
| IL273831B2 (en) | 2017-10-19 | 2024-10-01 | Vertex Pharma | Crystalline forms and compositions of cftr modulators |
| CN111757874B (zh) | 2017-12-08 | 2024-03-08 | 弗特克斯药品有限公司 | 用于制备囊性纤维化跨膜传导调节因子的调节剂的方法 |
| TWI810243B (zh) | 2018-02-05 | 2023-08-01 | 美商維泰克斯製藥公司 | 用於治療囊腫纖化症之醫藥組合物 |
| WO2019197620A1 (de) | 2018-04-13 | 2019-10-17 | Bayer Cropscience Aktiengesellschaft | Verwendung von tetramsäurederivaten zur bekämpfung von speziellen insekten |
| US11414439B2 (en) | 2018-04-13 | 2022-08-16 | Vertex Pharmaceuticals Incorporated | Modulators of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulator |
| WO2019197617A1 (de) | 2018-04-13 | 2019-10-17 | Bayer Cropscience Aktiengesellschaft | Verwendung von tetramsäurederivaten zur bekämpfung von tierischen schädlingen durch angiessen, tröpfchenapplikation. pflanzlochbehandlung oder furchenapplikation |
| CN111970926A (zh) | 2018-04-13 | 2020-11-20 | 拜耳作物科学股份公司 | 特特拉姆酸衍生物通过灌溉施用或滴浇施用防治害虫的用途 |
| BR112020020766A2 (pt) | 2018-04-13 | 2021-01-19 | Bayer Cropscience Aktiengesellschaft | Uso de derivados de ácido tetrâmico para controle de insetos específicos |
| WO2019197652A1 (de) | 2018-04-13 | 2019-10-17 | Bayer Aktiengesellschaft | Feststoff-formulierung insektizider mischungen |
| AR115088A1 (es) | 2018-05-15 | 2020-11-25 | Bayer Ag | Espirociclohexilpirrolin-2-onas y su uso como herbicidas |
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-
2010
- 2010-03-05 ES ES10708924.5T patent/ES2632567T3/es active Active
- 2010-03-05 HU HUE10708924A patent/HUE035166T2/en unknown
- 2010-03-05 JP JP2011553331A patent/JP5840955B2/ja not_active Expired - Fee Related
- 2010-03-05 EP EP16193742.0A patent/EP3153503A1/de not_active Withdrawn
- 2010-03-05 CN CN201310556920.7A patent/CN103641709B/zh not_active Expired - Fee Related
- 2010-03-05 MX MX2013011965A patent/MX338802B/es unknown
- 2010-03-05 CA CA2754847A patent/CA2754847C/en not_active Expired - Fee Related
- 2010-03-05 PL PL10708924T patent/PL2406216T3/pl unknown
- 2010-03-05 CN CN201080011864.3A patent/CN102348684B/zh not_active Expired - Fee Related
- 2010-03-05 MX MX2011009188A patent/MX2011009188A/es active IP Right Grant
- 2010-03-05 BR BRPI1008949-7A patent/BRPI1008949B1/pt not_active IP Right Cessation
- 2010-03-05 EA EA201190190A patent/EA024266B1/ru not_active IP Right Cessation
- 2010-03-05 WO PCT/EP2010/001392 patent/WO2010102758A2/de not_active Ceased
- 2010-03-05 EP EP10708924.5A patent/EP2406216B1/de not_active Not-in-force
- 2010-03-05 KR KR1020117023789A patent/KR101703633B1/ko not_active Expired - Fee Related
- 2010-03-05 AU AU2010223535A patent/AU2010223535B2/en not_active Ceased
- 2010-03-08 AR ARP100100694A patent/AR075848A1/es active IP Right Grant
- 2010-03-11 US US12/659,536 patent/US8518985B2/en not_active Expired - Fee Related
-
2013
- 2013-07-22 US US13/947,447 patent/US9045390B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EA201190190A1 (ru) | 2012-02-28 |
| ES2632567T3 (es) | 2017-09-14 |
| CN102348684B (zh) | 2014-11-12 |
| WO2010102758A2 (de) | 2010-09-16 |
| HUE035166T2 (en) | 2018-05-02 |
| EA024266B1 (ru) | 2016-09-30 |
| AR075848A1 (es) | 2011-05-04 |
| US20140213813A9 (en) | 2014-07-31 |
| US20100311593A1 (en) | 2010-12-09 |
| BRPI1008949A8 (pt) | 2016-05-03 |
| CA2754847C (en) | 2017-07-11 |
| CN102348684A (zh) | 2012-02-08 |
| AU2010223535B2 (en) | 2015-09-10 |
| KR20110132591A (ko) | 2011-12-08 |
| PL2406216T3 (pl) | 2017-09-29 |
| US8518985B2 (en) | 2013-08-27 |
| US9045390B2 (en) | 2015-06-02 |
| CA2754847A1 (en) | 2010-09-16 |
| CN103641709B (zh) | 2017-08-25 |
| JP5840955B2 (ja) | 2016-01-06 |
| JP2012520242A (ja) | 2012-09-06 |
| US20140031577A1 (en) | 2014-01-30 |
| MX2011009188A (es) | 2011-09-26 |
| AU2010223535A1 (en) | 2011-09-22 |
| BRPI1008949A2 (pt) | 2015-09-01 |
| EP3153503A1 (de) | 2017-04-12 |
| EP2406216A2 (de) | 2012-01-18 |
| WO2010102758A3 (de) | 2011-01-20 |
| EP2406216B1 (de) | 2017-04-19 |
| BRPI1008949B1 (pt) | 2018-07-10 |
| CN103641709A (zh) | 2014-03-19 |
| KR101703633B1 (ko) | 2017-02-07 |
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