UY37098A - Moduladores de ror-gamma - Google Patents
Moduladores de ror-gammaInfo
- Publication number
- UY37098A UY37098A UY0001037098A UY37098A UY37098A UY 37098 A UY37098 A UY 37098A UY 0001037098 A UY0001037098 A UY 0001037098A UY 37098 A UY37098 A UY 37098A UY 37098 A UY37098 A UY 37098A
- Authority
- UY
- Uruguay
- Prior art keywords
- ror
- gamma modulators
- diseases
- formula
- treatment
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 230000001363 autoimmune Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037765 diseases and disorders Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 230000002503 metabolic effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/10—Radicals substituted by halogen atoms or nitro radicals
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
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- A61K31/4192—1,2,3-Triazoles
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- A61K31/42—Oxazoles
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| KR102702236B1 (ko) | 2015-05-15 | 2024-09-04 | 오리진 온콜로지 리미티드 | Ror 감마 조절제로서의 치환된 테트라하이드로퀴놀리논 화합물 |
| EP3331876B1 (en) | 2015-08-05 | 2020-10-07 | Vitae Pharmaceuticals, LLC | Modulators of ror-gamma |
| EP3868750A1 (en) | 2015-11-20 | 2021-08-25 | Vitae Pharmaceuticals, LLC | Modulators of ror-gamma |
| TWI757266B (zh) | 2016-01-29 | 2022-03-11 | 美商維它藥物有限責任公司 | ROR-γ調節劑 |
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-
2017
- 2017-01-26 TW TW106103216A patent/TWI757266B/zh not_active IP Right Cessation
- 2017-01-26 TW TW111104096A patent/TW202220968A/zh unknown
- 2017-01-27 US US16/073,503 patent/US10829481B2/en active Active
- 2017-01-27 RU RU2021133444A patent/RU2021133444A/ru unknown
- 2017-01-27 CA CA3011838A patent/CA3011838A1/en active Pending
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- 2017-01-27 JP JP2018539070A patent/JP6948333B2/ja not_active Expired - Fee Related
- 2017-01-27 WO PCT/US2017/015220 patent/WO2017132432A1/en not_active Ceased
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- 2017-01-27 RU RU2018127360A patent/RU2760366C2/ru active
- 2017-01-27 AU AU2017212577A patent/AU2017212577B2/en not_active Ceased
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- 2017-01-27 BR BR112018015273A patent/BR112018015273A2/pt not_active Application Discontinuation
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- 2017-01-27 CN CN201780009016.0A patent/CN109071509B/zh not_active Expired - Fee Related
- 2017-01-27 MA MA045646A patent/MA45646A/fr unknown
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- 2017-01-27 KR KR1020187024271A patent/KR20180100697A/ko not_active Withdrawn
- 2017-01-27 EP EP21184347.9A patent/EP3939974A1/en not_active Withdrawn
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2018
- 2018-07-28 SA SA518392101A patent/SA518392101B1/ar unknown
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2020
- 2020-09-17 US US17/023,871 patent/US20210094940A1/en not_active Abandoned
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2021
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| US20190352286A1 (en) | 2019-11-21 |
| EP3408268B1 (en) | 2021-08-04 |
| SA518392101B1 (ar) | 2022-03-16 |
| CN109071509B (zh) | 2021-11-30 |
| JP6948333B2 (ja) | 2021-10-13 |
| MX2018009257A (es) | 2018-11-09 |
| TWI757266B (zh) | 2022-03-11 |
| JP2019503385A (ja) | 2019-02-07 |
| EP3408268B8 (en) | 2023-12-06 |
| BR112018015273A2 (pt) | 2018-12-18 |
| US10829481B2 (en) | 2020-11-10 |
| CA3011838A1 (en) | 2017-08-03 |
| MA45646A (fr) | 2021-03-24 |
| AU2017212577B2 (en) | 2021-05-13 |
| WO2017132432A1 (en) | 2017-08-03 |
| RU2021133444A (ru) | 2021-11-29 |
| WO2017132432A8 (en) | 2017-08-31 |
| AU2017212577A1 (en) | 2018-08-02 |
| TW201734001A (zh) | 2017-10-01 |
| EP3408268A1 (en) | 2018-12-05 |
| EP3939974A1 (en) | 2022-01-19 |
| MA55328A (fr) | 2022-01-19 |
| US20210094940A1 (en) | 2021-04-01 |
| CN109071509A (zh) | 2018-12-21 |
| CN114230523A (zh) | 2022-03-25 |
| MX381313B (es) | 2025-03-12 |
| TW202220968A (zh) | 2022-06-01 |
| RU2760366C2 (ru) | 2021-11-24 |
| JP2021193131A (ja) | 2021-12-23 |
| KR20180100697A (ko) | 2018-09-11 |
| RU2018127360A3 (enExample) | 2020-04-06 |
| RU2018127360A (ru) | 2020-03-02 |
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