UY38001A - Compuestos que inhiben las proteínas ras mutantes g12c - Google Patents

Compuestos que inhiben las proteínas ras mutantes g12c

Info

Publication number
UY38001A
UY38001A UY0001038001A UY38001A UY38001A UY 38001 A UY38001 A UY 38001A UY 0001038001 A UY0001038001 A UY 0001038001A UY 38001 A UY38001 A UY 38001A UY 38001 A UY38001 A UY 38001A
Authority
UY
Uruguay
Prior art keywords
compounds
inhibit
mutant ras
ras proteins
refers
Prior art date
Application number
UY0001038001A
Other languages
English (en)
Inventor
Grant Kettle Jason
Kaur Bagal Sharanjeet
Richard Robb Graeme
Michael Smith James
Joseph CASSAR Doyle
Lyman Feron James
Woolf Goldberg Frederick
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of UY38001A publication Critical patent/UY38001A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La memoria descriptiva se refiere a compuestos de Fórmula (I) (I) y sales farmacéuticamente aceptables de los mismos. La memoria descriptiva también se refiere a procesos e intermedios usados para su preparación, a composiciones farmacéuticas que los contienen y a su uso en el tratamiento de trastornos proliferativos celulares.
UY0001038001A 2017-12-08 2018-12-07 Compuestos que inhiben las proteínas ras mutantes g12c UY38001A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762596331P 2017-12-08 2017-12-08
US201862678418P 2018-05-31 2018-05-31

Publications (1)

Publication Number Publication Date
UY38001A true UY38001A (es) 2019-05-31

Family

ID=64664739

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001038001A UY38001A (es) 2017-12-08 2018-12-07 Compuestos que inhiben las proteínas ras mutantes g12c

Country Status (4)

Country Link
US (1) US10597405B2 (es)
TW (1) TW201938561A (es)
UY (1) UY38001A (es)
WO (1) WO2019110751A1 (es)

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Also Published As

Publication number Publication date
TW201938561A (zh) 2019-10-01
US10597405B2 (en) 2020-03-24
WO2019110751A1 (en) 2019-06-13
US20190177338A1 (en) 2019-06-13

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