TR201901431T4 - Purpura tedavisi için bileşimler ve yöntemler. - Google Patents

Purpura tedavisi için bileşimler ve yöntemler. Download PDF

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Publication number
TR201901431T4
TR201901431T4 TR2019/01431T TR201901431T TR201901431T4 TR 201901431 T4 TR201901431 T4 TR 201901431T4 TR 2019/01431 T TR2019/01431 T TR 2019/01431T TR 201901431 T TR201901431 T TR 201901431T TR 201901431 T4 TR201901431 T4 TR 201901431T4
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TR
Turkey
Prior art keywords
receptor agonist
compositions
adrenergic receptor
methods
selective
Prior art date
Application number
TR2019/01431T
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English (en)
Inventor
D Shanler Stuart
Ondo Andrew
Original Assignee
Aclaris Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aclaris Therapeutics Inc filed Critical Aclaris Therapeutics Inc
Publication of TR201901431T4 publication Critical patent/TR201901431T4/tr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)

Abstract

Bu buluşun düzenlemeleri, purpura tedavisi için bileşimlere ve yöntemlere yöneliktir. Tercih edilen bileşimler, ciltte hemorajik (purpurik) lezyonların kozmetik görünümünü iyileştirmek ve geliştirmek için farmasötik olarak kabul edilebilir bir taşıyıcıda, seçici bir alfa1 adrenerjik reseptör agonisti, seçici alfa2 adrenerjik reseptör agonisti, seçici olmayan alfa1 / alfa2 adrenerjik reseptör agonisti, alfa2 adrenerjik reseptör agonist aktivitesi olan ajanlar ve bunların kombinasyonlarından seçilen alfa adrenerjik agonisti içerir.
TR2019/01431T 2007-11-16 2008-11-17 Purpura tedavisi için bileşimler ve yöntemler. TR201901431T4 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US98856407P 2007-11-16 2007-11-16

Publications (1)

Publication Number Publication Date
TR201901431T4 true TR201901431T4 (tr) 2019-02-21

Family

ID=40639204

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2019/01431T TR201901431T4 (tr) 2007-11-16 2008-11-17 Purpura tedavisi için bileşimler ve yöntemler.

Country Status (19)

Country Link
US (4) US8114898B2 (tr)
EP (3) EP2818184B1 (tr)
JP (2) JP5670196B2 (tr)
KR (1) KR101577471B1 (tr)
CN (1) CN101896204B (tr)
AU (1) AU2008322411C1 (tr)
BR (1) BRPI0819075A2 (tr)
CA (1) CA2703109C (tr)
DK (1) DK2818184T3 (tr)
ES (1) ES2709120T3 (tr)
HR (1) HRP20190214T1 (tr)
HU (1) HUE042931T2 (tr)
IL (1) IL205704A (tr)
MX (1) MX2010005331A (tr)
PL (1) PL2818184T3 (tr)
PT (1) PT2818184T (tr)
SI (1) SI2818184T1 (tr)
TR (1) TR201901431T4 (tr)
WO (1) WO2009065116A1 (tr)

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EP3498299A1 (en) 2019-06-19
CN101896204A (zh) 2010-11-24
WO2009065116A1 (en) 2009-05-22
ES2709120T3 (es) 2019-04-15
AU2008322411C1 (en) 2015-03-12
DK2818184T3 (en) 2019-02-25
PT2818184T (pt) 2019-01-28
KR101577471B1 (ko) 2015-12-14
EP2207424A4 (en) 2011-11-30
JP5670196B2 (ja) 2015-02-18
JP2015071601A (ja) 2015-04-16
IL205704A (en) 2015-06-30
US20120177585A1 (en) 2012-07-12

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