EA201100132A1 - Единичная доза ападеносона - Google Patents
Единичная доза ападеносонаInfo
- Publication number
- EA201100132A1 EA201100132A1 EA201100132A EA201100132A EA201100132A1 EA 201100132 A1 EA201100132 A1 EA 201100132A1 EA 201100132 A EA201100132 A EA 201100132A EA 201100132 A EA201100132 A EA 201100132A EA 201100132 A1 EA201100132 A1 EA 201100132A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- single dose
- apadenoson
- pharmacological
- agent
- apadenosone
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Abstract
Настоящее изобретение обеспечивает единичную дозу Ападеносона, фармакологического стресс-агента, и его применение в качестве фармакологического агента для визуализации миокардиальной перфузии.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7816908P | 2008-07-03 | 2008-07-03 | |
US15593709P | 2009-02-27 | 2009-02-27 | |
PCT/US2009/003939 WO2010002473A1 (en) | 2008-07-03 | 2009-07-02 | Unit dosage of apadenoson |
Publications (2)
Publication Number | Publication Date |
---|---|
EA201100132A1 true EA201100132A1 (ru) | 2011-08-30 |
EA022348B1 EA022348B1 (ru) | 2015-12-30 |
Family
ID=41152021
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201100132A EA022348B1 (ru) | 2008-07-03 | 2009-07-02 | Единичная доза ападеносона |
Country Status (24)
Country | Link |
---|---|
US (6) | US20100003193A1 (ru) |
EP (1) | EP2306971B1 (ru) |
JP (2) | JP2011526894A (ru) |
KR (2) | KR20140021726A (ru) |
CN (1) | CN102119023B (ru) |
AU (1) | AU2009266317B2 (ru) |
BR (1) | BRPI0913939A2 (ru) |
CA (1) | CA2729819C (ru) |
CY (1) | CY1116283T1 (ru) |
DK (1) | DK2306971T3 (ru) |
EA (1) | EA022348B1 (ru) |
ES (1) | ES2537069T3 (ru) |
HK (1) | HK1156250A1 (ru) |
HR (1) | HRP20150454T1 (ru) |
IL (2) | IL210428A (ru) |
MX (1) | MX2011000193A (ru) |
MY (1) | MY161655A (ru) |
NZ (1) | NZ590489A (ru) |
PL (1) | PL2306971T3 (ru) |
PT (1) | PT2306971E (ru) |
SI (1) | SI2306971T1 (ru) |
SM (1) | SMT201500123B (ru) |
WO (1) | WO2010002473A1 (ru) |
ZA (1) | ZA201100163B (ru) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010002473A1 (en) | 2008-07-03 | 2010-01-07 | University Of Virginia Patent Foundation | Unit dosage of apadenoson |
CA2863685C (en) | 2012-02-03 | 2020-10-13 | Adenobio N.V. | A method of using adenosine and dipyridamole for pharmacologic stress testing, with specific compositions, unit dosage forms and kits |
CN109020881B (zh) * | 2018-06-28 | 2020-04-28 | 新发药业有限公司 | 一种阿帕替尼的制备方法 |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5091171B2 (en) | 1986-12-23 | 1997-07-15 | Tristrata Inc | Amphoteric compositions and polymeric forms of alpha hydroxyacids and their therapeutic use |
DE69120840T2 (de) * | 1990-02-21 | 1996-11-21 | Nz Government | Supraleiter auf Thalliumbasis substituiert durch seltene Erden |
IT1263831B (it) | 1993-01-29 | 1996-09-04 | Paolo Chiesi | Complessi di inclusione multicomponente ad elevata solubilita' costituiti da un farmaco di tipo basico, un acido ed una ciclodestrina |
NZ513096A (en) | 1999-02-01 | 2003-01-31 | Univ Virginia | Compositions for treating inflammatory response |
US7427606B2 (en) | 1999-02-01 | 2008-09-23 | University Of Virginia Patent Foundation | Method to reduce inflammatory response in transplanted tissue |
US6232297B1 (en) * | 1999-02-01 | 2001-05-15 | University Of Virginia Patent Foundation | Methods and compositions for treating inflammatory response |
US6322771B1 (en) * | 1999-06-18 | 2001-11-27 | University Of Virginia Patent Foundation | Induction of pharmacological stress with adenosine receptor agonists |
WO2002034966A1 (fr) * | 2000-10-23 | 2002-05-02 | National Institute Of Advanced Industrial Science And Technology | Structure composite et procede et appareil destines a sa fabrication |
US6620645B2 (en) * | 2000-11-16 | 2003-09-16 | G.T. Equipment Technologies, Inc | Making and connecting bus bars on solar cells |
JP4514452B2 (ja) | 2001-10-01 | 2010-07-28 | ユニバーシティ オブ バージニア パテント ファウンデーション | A2aアゴニスト活性を有する2−プロピルアデノシン・アナログおよびその組成物 |
JP4615221B2 (ja) * | 2002-02-27 | 2011-01-19 | フェリング ベスローテン フェンノートシャップ | ヘプタペプチドオキシトシンアナログを製造するための中間体及び方法 |
WO2003086408A1 (en) | 2002-04-10 | 2003-10-23 | University Of Virginia Patent Foundation | Use of a2a adenosine receptor agonists for the treatment of inflammatory diseases |
US6662088B1 (en) * | 2002-06-28 | 2003-12-09 | General Electric Company | Methods and systems for inspecting aircraft fuselage frames |
US7396825B2 (en) | 2004-05-03 | 2008-07-08 | University Of Virginia Patent Foundation | Agonists of A2A adenosine receptors for treatment of diabetic nephropathy |
CN101068825B (zh) | 2004-08-02 | 2013-05-08 | 弗吉尼亚大学专利基金会 | 具有a2a激动剂活性的具有修饰的5'-核糖基团的2-丙炔基腺苷类似物 |
DE602005011111D1 (de) | 2005-06-03 | 2009-01-02 | St Microelectronics Srl | Selbstjustiertes Verfahren zur Herstellung von Phasenwechselspeicherzellen |
US7767686B2 (en) | 2006-03-03 | 2010-08-03 | Covidien Ag | Method of using adenosine receptor blockers during tissue ablation |
DE102006022450A1 (de) | 2006-05-13 | 2007-11-15 | Lanxess Deutschland Gmbh | Wässrige Rußdispersionen für Ink-Jet |
CA2694983A1 (en) * | 2007-07-17 | 2009-01-22 | Combinatorx, Incorporated | Treatments of b-cell proliferative disorders |
TW200905703A (en) * | 2007-07-27 | 2009-02-01 | Delta Electronics Inc | Magnetic device and manufacturing method thereof |
WO2010002473A1 (en) | 2008-07-03 | 2010-01-07 | University Of Virginia Patent Foundation | Unit dosage of apadenoson |
-
2009
- 2009-07-02 WO PCT/US2009/003939 patent/WO2010002473A1/en active Application Filing
- 2009-07-02 US US12/496,949 patent/US20100003193A1/en not_active Abandoned
- 2009-07-02 KR KR1020147003142A patent/KR20140021726A/ko not_active Application Discontinuation
- 2009-07-02 MY MYPI2010006339A patent/MY161655A/en unknown
- 2009-07-02 CA CA2729819A patent/CA2729819C/en active Active
- 2009-07-02 EA EA201100132A patent/EA022348B1/ru not_active IP Right Cessation
- 2009-07-02 KR KR1020117002495A patent/KR20110028531A/ko active Application Filing
- 2009-07-02 ES ES09773926.2T patent/ES2537069T3/es active Active
- 2009-07-02 DK DK09773926.2T patent/DK2306971T3/en active
- 2009-07-02 MX MX2011000193A patent/MX2011000193A/es active IP Right Grant
- 2009-07-02 EP EP09773926.2A patent/EP2306971B1/en active Active
- 2009-07-02 PT PT97739262T patent/PT2306971E/pt unknown
- 2009-07-02 BR BRPI0913939A patent/BRPI0913939A2/pt not_active Application Discontinuation
- 2009-07-02 PL PL09773926T patent/PL2306971T3/pl unknown
- 2009-07-02 SI SI200931189T patent/SI2306971T1/sl unknown
- 2009-07-02 CN CN200980131395.6A patent/CN102119023B/zh active Active
- 2009-07-02 NZ NZ590489A patent/NZ590489A/xx not_active IP Right Cessation
- 2009-07-02 AU AU2009266317A patent/AU2009266317B2/en not_active Ceased
- 2009-07-02 JP JP2011516343A patent/JP2011526894A/ja not_active Withdrawn
-
2011
- 2011-01-02 IL IL210428A patent/IL210428A/en not_active IP Right Cessation
- 2011-01-06 ZA ZA2011/00163A patent/ZA201100163B/en unknown
- 2011-10-07 HK HK11110662.3A patent/HK1156250A1/xx not_active IP Right Cessation
-
2012
- 2012-07-09 US US13/544,364 patent/US20130017153A1/en not_active Abandoned
-
2013
- 2013-08-29 JP JP2013177622A patent/JP2013237702A/ja active Pending
- 2013-12-11 US US14/103,130 patent/US9415058B2/en active Active
-
2015
- 2015-04-27 HR HRP20150454TT patent/HRP20150454T1/hr unknown
- 2015-05-14 CY CY20151100432T patent/CY1116283T1/el unknown
- 2015-05-22 SM SM201500123T patent/SMT201500123B/xx unknown
-
2016
- 2016-05-10 IL IL245577A patent/IL245577B/en active IP Right Grant
- 2016-06-13 US US15/181,235 patent/US9662406B2/en active Active
-
2017
- 2017-05-19 US US15/600,303 patent/US20170252463A1/en not_active Abandoned
-
2018
- 2018-07-25 US US16/045,359 patent/US20190022253A1/en not_active Abandoned
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KZ KG MD TJ TM RU |