TR201816077T4 - Seçici bir cdk4/6 inhibitörünün katı formları. - Google Patents

Seçici bir cdk4/6 inhibitörünün katı formları. Download PDF

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Publication number
TR201816077T4
TR201816077T4 TR2018/16077T TR201816077T TR201816077T4 TR 201816077 T4 TR201816077 T4 TR 201816077T4 TR 2018/16077 T TR2018/16077 T TR 2018/16077T TR 201816077 T TR201816077 T TR 201816077T TR 201816077 T4 TR201816077 T4 TR 201816077T4
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free base
particle size
compound
approximately
arrangements
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TR2018/16077T
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Patrick Chekal Brian
Nathan Ide D
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Pfizer
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
TR2018/16077T 2013-02-21 2014-02-08 Seçici bir cdk4/6 inhibitörünün katı formları. TR201816077T4 (tr)

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US201361767761P 2013-02-21 2013-02-21

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TR2018/16077T TR201816077T4 (tr) 2013-02-21 2014-02-08 Seçici bir cdk4/6 inhibitörünün katı formları.

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US (2) US20160002223A1 (enExample)
EP (2) EP3431475B1 (enExample)
JP (3) JP6381016B2 (enExample)
KR (2) KR20150107872A (enExample)
CN (3) CN105008357A (enExample)
AR (1) AR094842A1 (enExample)
AU (1) AU2014220354B2 (enExample)
BR (1) BR112015019508A8 (enExample)
CA (1) CA2900322C (enExample)
CY (2) CY1120734T1 (enExample)
DK (2) DK3431475T3 (enExample)
ES (2) ES2694787T3 (enExample)
HK (2) HK1211032A1 (enExample)
HU (2) HUE054212T2 (enExample)
IL (1) IL240277B (enExample)
MX (2) MX386473B (enExample)
PL (2) PL3431475T3 (enExample)
PT (2) PT3431475T (enExample)
RU (1) RU2619944C2 (enExample)
SG (1) SG11201505680RA (enExample)
SI (2) SI3431475T1 (enExample)
TR (1) TR201816077T4 (enExample)
TW (2) TWI670269B (enExample)
WO (1) WO2014128588A1 (enExample)

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