TNSN05121A1 - Purines et leurs utilisations comme ligands des recepteurs de cannabinoides - Google Patents

Purines et leurs utilisations comme ligands des recepteurs de cannabinoides

Info

Publication number
TNSN05121A1
TNSN05121A1 TNP2005000121A TNSN05121A TNSN05121A1 TN SN05121 A1 TNSN05121 A1 TN SN05121A1 TN P2005000121 A TNP2005000121 A TN P2005000121A TN SN05121 A TNSN05121 A TN SN05121A TN SN05121 A1 TNSN05121 A1 TN SN05121A1
Authority
TN
Tunisia
Prior art keywords
ligands
purines
cannabinoid receptors
cannabinoid receptor
cannabinoid
Prior art date
Application number
TNP2005000121A
Other languages
English (en)
Inventor
David Andrew Griffith
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of TNSN05121A1 publication Critical patent/TNSN05121A1/fr

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/28—Oxygen atom
    • C07D473/30—Oxygen atom attached in position 6, e.g. hypoxanthine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/40—Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6

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Abstract

Des composés de formule (I) Qui jouent le rôle de ligands des récepteurs de cannabinoides et leurs utilisations dans le traitement de maladies en rapport avec la médiation des récepteurs de cannabinoides chez des animaux sont décrits dans le présent mémoire.
TNP2005000121A 2002-10-28 2005-04-28 Purines et leurs utilisations comme ligands des recepteurs de cannabinoides TNSN05121A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42187402P 2002-10-28 2002-10-28
PCT/IB2003/004619 WO2004037823A1 (fr) 2002-10-28 2003-10-21 Composes puriniques et leurs utilisations comme ligands de recepteurs des cannabinoides

Publications (1)

Publication Number Publication Date
TNSN05121A1 true TNSN05121A1 (fr) 2007-05-14

Family

ID=32176739

Family Applications (1)

Application Number Title Priority Date Filing Date
TNP2005000121A TNSN05121A1 (fr) 2002-10-28 2005-04-28 Purines et leurs utilisations comme ligands des recepteurs de cannabinoides

Country Status (45)

Country Link
US (2) US7129239B2 (fr)
EP (1) EP1558615B8 (fr)
JP (2) JP3954618B2 (fr)
KR (1) KR100674560B1 (fr)
CN (3) CN1955181A (fr)
AP (1) AP1916A (fr)
AR (1) AR041835A1 (fr)
AT (1) ATE371658T1 (fr)
AU (1) AU2003269368B2 (fr)
BR (1) BR0314918A (fr)
CA (1) CA2503900C (fr)
CO (1) CO5560546A2 (fr)
CR (1) CR7812A (fr)
CU (1) CU23535A3 (fr)
CY (1) CY1107505T1 (fr)
DE (1) DE60316012T2 (fr)
DK (1) DK1558615T3 (fr)
DO (1) DOP2003000742A (fr)
EA (1) EA008176B1 (fr)
EC (1) ECSP055767A (fr)
EG (1) EG24662A (fr)
ES (1) ES2291669T3 (fr)
GE (1) GEP20084325B (fr)
GT (1) GT200300232A (fr)
HK (2) HK1081189A1 (fr)
HR (1) HRP20050378A2 (fr)
IS (1) IS2602B (fr)
MA (1) MA27479A1 (fr)
MX (1) MXPA05003882A (fr)
MY (1) MY140010A (fr)
NL (1) NL1024643C2 (fr)
NO (1) NO332195B1 (fr)
NZ (1) NZ539589A (fr)
OA (1) OA13080A (fr)
PE (1) PE20040781A1 (fr)
PL (1) PL376311A1 (fr)
PT (1) PT1558615E (fr)
RS (2) RS20050306A (fr)
SG (1) SG148071A1 (fr)
TN (1) TNSN05121A1 (fr)
TW (1) TWI327567B (fr)
UA (1) UA79507C2 (fr)
UY (1) UY28044A1 (fr)
WO (1) WO2004037823A1 (fr)
ZA (1) ZA200503378B (fr)

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