SV2003001144A - FORMAS CRISTALINAS DE LA SAL DE CALCIO DEL ACIDO [R-(R*,R*)]-2-(4-FLUOROFENIL)-ß,ô-DIHIDROXI-5-(1-METILETIL)-3-FENIL-4[(FENILAMINO)CARBONIL]-1H-PIRROL-1-HEPTANOICO (2:1) REF. PC430-01FJT - Google Patents
FORMAS CRISTALINAS DE LA SAL DE CALCIO DEL ACIDO [R-(R*,R*)]-2-(4-FLUOROFENIL)-ß,ô-DIHIDROXI-5-(1-METILETIL)-3-FENIL-4[(FENILAMINO)CARBONIL]-1H-PIRROL-1-HEPTANOICO (2:1) REF. PC430-01FJTInfo
- Publication number
- SV2003001144A SV2003001144A SV2002001144A SV2002001144A SV2003001144A SV 2003001144 A SV2003001144 A SV 2003001144A SV 2002001144 A SV2002001144 A SV 2002001144A SV 2002001144 A SV2002001144 A SV 2002001144A SV 2003001144 A SV2003001144 A SV 2003001144A
- Authority
- SV
- El Salvador
- Prior art keywords
- heptanoico
- 01fjt
- carbonil
- pirrol
- phenylamine
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Abstract
FORMAS CRISTALINAS DE LA SAL DE CALCIO DEL ÁCIDO [R-(R*,R*)]-2-(4-FLUOROFENIL)-ß,Ô-DIHIDROXI-5-(1-METILETIL)-3-FENIL-4[(FENILAMINO)CARBONIL]-1H-PIRROL-1-HEPTANOICO (2:1) REF. PC430-01FJT
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US30204901P | 2001-06-29 | 2001-06-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
SV2003001144A true SV2003001144A (es) | 2003-03-18 |
Family
ID=23166039
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SV2002001144A SV2003001144A (es) | 2001-06-29 | 2002-06-28 | FORMAS CRISTALINAS DE LA SAL DE CALCIO DEL ACIDO [R-(R*,R*)]-2-(4-FLUOROFENIL)-ß,ô-DIHIDROXI-5-(1-METILETIL)-3-FENIL-4[(FENILAMINO)CARBONIL]-1H-PIRROL-1-HEPTANOICO (2:1) REF. PC430-01FJT |
Country Status (40)
Country | Link |
---|---|
US (5) | US6605729B1 (es) |
EP (2) | EP1423364B1 (es) |
JP (2) | JP3965155B2 (es) |
KR (1) | KR100609371B1 (es) |
CN (2) | CN101215253A (es) |
AP (1) | AP1571A (es) |
AR (1) | AR036118A1 (es) |
AU (1) | AU2002258092B2 (es) |
BG (1) | BG108393A (es) |
BR (1) | BR0210666A (es) |
CA (1) | CA2450111C (es) |
CR (2) | CR7170A (es) |
CZ (1) | CZ20033478A3 (es) |
DO (1) | DOP2002000413A (es) |
EA (1) | EA005317B1 (es) |
EC (1) | ECSP034928A (es) |
EE (1) | EE200300597A (es) |
ES (1) | ES2558565T3 (es) |
GE (1) | GEP20053546B (es) |
HR (1) | HRP20031039A2 (es) |
HU (1) | HUP0400381A2 (es) |
IL (1) | IL158790A0 (es) |
MA (1) | MA27044A1 (es) |
MX (1) | MXPA03010266A (es) |
MY (1) | MY122907A (es) |
NO (1) | NO326170B1 (es) |
NZ (1) | NZ529557A (es) |
OA (1) | OA12636A (es) |
PA (1) | PA8549501A1 (es) |
PE (1) | PE20030124A1 (es) |
PL (1) | PL367943A1 (es) |
RS (1) | RS100003A (es) |
SK (1) | SK16002003A3 (es) |
SV (1) | SV2003001144A (es) |
TN (1) | TNSN03147A1 (es) |
TW (1) | TWI319396B (es) |
UA (1) | UA74075C2 (es) |
UY (1) | UY27359A1 (es) |
WO (1) | WO2003004470A1 (es) |
ZA (1) | ZA200308731B (es) |
Families Citing this family (54)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI94339C (fi) | 1989-07-21 | 1995-08-25 | Warner Lambert Co | Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi |
BR9609872A (pt) | 1995-07-17 | 1999-03-23 | Warner Lambert Co | Hemi sal de cálcio de ácido (R-(R*R*)]-2-(4-fluorfenil-)-beta delta-diidróxi-5-(1-metiletil)-3-fenil-4- [(fenilamino) carbonil]-1H- pirrol-1heptanóico (atorvasta-tina)c ristalino |
WO1999026657A1 (en) * | 1997-11-25 | 1999-06-03 | Musc Foundation For Research Development | Inhibitors of nitric oxide synthase |
US20080275104A1 (en) * | 1997-11-25 | 2008-11-06 | Musc Foundation For Research Development | Methods of treating juvenile type 1 diabetes mellitus |
US20040072138A1 (en) * | 1997-11-25 | 2004-04-15 | Medical University Of South Carolina | Attenuation of ischemia/reperfusion injury |
US7411075B1 (en) | 2000-11-16 | 2008-08-12 | Teva Pharmaceutical Industries Ltd. | Polymorphic form of atorvastatin calcium |
CN1535139A (zh) * | 2000-11-03 | 2004-10-06 | ������ҩ��ҵ����˾ | 阿伐他丁半钙形式ⅶ |
IL156055A0 (en) * | 2000-11-30 | 2003-12-23 | Teva Pharma | Novel crystal forms of atorvastatin hemi calcium and processes for their preparation as well as novel processes for preparing other forms |
US7501450B2 (en) * | 2000-11-30 | 2009-03-10 | Teva Pharaceutical Industries Ltd. | Crystal forms of atorvastatin hemi-calcium and processes for their preparation as well as novel processes for preparing other forms |
MXPA03005879A (es) * | 2000-12-27 | 2003-09-10 | Ciba Sc Holding Ag | Formas cristalinas de atorvastatina. |
AP1571A (en) * | 2001-06-29 | 2006-02-10 | Warner Lambert Co | Crystalline forms of 'R-(R* ,R*)!-2-(4- fluorophenyl)-beta, delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-'phenylamino)carbonyl!-1H-pyrrole-1-heptanoic acid calcium salt (2:1) (atorvastatin) |
US7074818B2 (en) * | 2001-07-30 | 2006-07-11 | Dr. Reddy's Laboratories Limited | Crystalline forms VI and VII of Atorvastatin calcium |
US20060020137A1 (en) * | 2001-11-29 | 2006-01-26 | Limor Tessler | Novel crystal forms of atorvastatin hemi-calcium and processes for their preparation as well as novel processes for preparing other forms |
JP2005519076A (ja) * | 2002-02-15 | 2005-06-30 | テバ ファーマシューティカル インダストリーズ リミティド | アトルバスタチンヘミカルシウムの新規結晶形態およびその調製方法ならびにアトルバスタチンヘミカルシウム形態i、viiiおよびixの新規調製方法 |
CA2475123A1 (en) * | 2002-02-19 | 2003-08-28 | Teva Pharmaceutical Industries Ltd. | Desolvating solvates of atorvastatin hemi-calcium |
EP1562583A1 (en) * | 2002-09-03 | 2005-08-17 | Morepen Laboratories Ltd. | Atorvastatin calcium form vi or hydrates thereof |
CA2508871C (en) * | 2002-11-28 | 2008-09-09 | Teva Pharmaceutical Industries Ltd. | Crystalline form f of atorvastatin hemi-calcium salt |
EP1424324A1 (en) * | 2002-11-28 | 2004-06-02 | Teva Pharmaceutical Industries Limited | Crystalline form F of Atorvastatin hemi-calcium salt |
US7790197B2 (en) * | 2003-06-09 | 2010-09-07 | Warner-Lambert Company Llc | Pharmaceutical compositions of atorvastatin |
US20040253305A1 (en) * | 2003-06-12 | 2004-12-16 | Luner Paul E. | Pharmaceutical compositions of atorvastatin |
US20050271717A1 (en) | 2003-06-12 | 2005-12-08 | Alfred Berchielli | Pharmaceutical compositions of atorvastatin |
US7655692B2 (en) * | 2003-06-12 | 2010-02-02 | Pfizer Inc. | Process for forming amorphous atorvastatin |
JP2007516294A (ja) * | 2003-12-23 | 2007-06-21 | エムユーエスシー ファウンデーション フォー リサーチ ディベロップメント | 炎症性の疾患または症状の予防および治療のための方法および組成物 |
ES2381473T3 (es) | 2004-03-17 | 2012-05-28 | Ranbaxy Laboratories Limited | Procedimiento para la preparación de atorvastatina cálcica en forma amorfa |
WO2005090301A1 (en) * | 2004-03-17 | 2005-09-29 | Ranbaxy Laboratories Limited | Crystalline form of atorvastatin hemi calcium |
CA2649054A1 (en) | 2004-05-05 | 2005-11-10 | Pfizer Products Inc. | Salt forms of [r-(r*,r*)]-2-(4-fluorophenyl)-.beta., .delta.-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptanoic acid |
MX2007000765A (es) | 2004-07-20 | 2007-03-28 | Warner Lambert Co | Formas cristalinas de sal de calcio del acido (r-(r*, r*))-2- (4-fluorofenil)- beta,gama- dihidroxi-5- (1-metiletil)-3 -fenil-4-((fenilamino) (carbonil)-1ih -pirrol-1- heptanoico (2:1). |
ES2263407T1 (es) * | 2004-09-28 | 2006-12-16 | Teva Pharmaceutical Industries Ltd | Procedimiento para la preparacion de formas de atorvastatina calcica sustancialmente libres de impurezas. |
NZ554541A (en) | 2004-10-28 | 2011-01-28 | Warner Lambert Co | Process for forming amorphous atorvastatin |
WO2006048894A1 (en) * | 2004-11-05 | 2006-05-11 | Morepen Laboratories Limited | Novel crystalline forms of atorvastatin calcium and processes for preparing them. |
EP1814541A4 (en) * | 2004-11-22 | 2009-10-28 | Dexcel Pharma Technologies Ltd | STABLE ATORVASTATIN FORMULATIONS |
WO2006059224A1 (en) * | 2004-12-02 | 2006-06-08 | Warner-Lambert Company Llc | Pharmaceutical compositions of amorphous atorvastatin and process for preparing same |
EP1688850A1 (en) | 2005-02-07 | 2006-08-09 | Sony Ericsson Mobile Communications AB | Generic parser for electronic devices |
US8506646B2 (en) * | 2005-04-29 | 2013-08-13 | Warsaw Orthopedic, Inc. | Multi-purpose medical implant devices |
US8092464B2 (en) * | 2005-04-30 | 2012-01-10 | Warsaw Orthopedic, Inc. | Syringe devices and methods useful for delivering osteogenic material |
EP1923057A1 (en) * | 2005-11-21 | 2008-05-21 | Teva Pharmaceutical Industries Ltd | Atorvastatin pharmaceutical formulation |
DK1957452T3 (da) * | 2005-11-21 | 2010-07-26 | Warner Lambert Co | Nye former af [R-(R*,R*)]-2-(4-fluorphenyl)-B,B-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-heptansyre- magnesium |
RU2395280C2 (ru) * | 2005-11-21 | 2010-07-27 | Тева Фармасьютикл Индастриес Лтд. | Фармацевтическая лекарственная форма аторвастатина |
KR20100023059A (ko) | 2005-12-13 | 2010-03-03 | 테바 파마슈티컬 인더스트리즈 리미티드 | 아토바스타틴 헤미칼슘의 결정형 및 이의 제조 방법 |
US7834195B2 (en) * | 2007-01-24 | 2010-11-16 | Apotex Pharmachem Inc. | Atorvastatin calcium propylene glycol solvates |
KR100878140B1 (ko) | 2007-01-29 | 2009-01-12 | 한미약품 주식회사 | 아토바스타틴의 스트론튬염 또는 이의 수화물, 및 이를포함하는 약학 조성물 |
CN101657419A (zh) * | 2007-03-02 | 2010-02-24 | 东亚制药株式会社 | 吡咯基庚酸衍生物的新晶型 |
US20080227846A1 (en) * | 2007-03-13 | 2008-09-18 | Musc Foundation For Research Development | Methods of treating juvenile type 1 diabetes mellitus |
WO2008123953A1 (en) * | 2007-04-02 | 2008-10-16 | Merck & Co., Inc. | Anti-hypercholesterolemic compound |
DE102007052071A1 (de) | 2007-10-30 | 2009-05-07 | Stada Arzneimittel Ag | Stabilisiertes Atorvastatin |
CN102976996B (zh) * | 2009-05-27 | 2015-08-19 | 峡江和美药业有限公司 | 阿伐他汀半锶盐多晶型物、其制备和作为HMG-CoA酶抑制剂的应用 |
US9334266B2 (en) | 2009-09-04 | 2016-05-10 | The University Of Toledo | Catalysts and related processes for producing optically pure beta-lactones from aldehydes and compositions produced thereby |
CZ201039A3 (cs) | 2010-01-19 | 2011-07-27 | Zentiva, K. S | Zpusob prumyslové výroby amorfní formy hemivápenaté soli (3R,5R) 7-[3-fenyl-4-fenylkarbamoyl-2-(4-fluorfenyl)-5-isopropylpyrrol-1-yl]-3,5-dihydroxyheptanové kyseliny (atorvastatinu) s vysokým specifickým povrchem a jeho použití v lékové forme |
KR20120011249A (ko) * | 2010-07-28 | 2012-02-07 | 주식회사 경보제약 | 아토바스타틴 헤미칼슘염의 신규한 결정형, 이의 수화물, 및 그의 제조방법 |
EP2726456A1 (en) * | 2011-07-01 | 2014-05-07 | DSM Sinochem Pharmaceuticals Netherlands B.V. | Micronized crystals of atorvastatin hemicalcium |
CN104945300B (zh) * | 2015-06-17 | 2017-05-10 | 北京嘉林药业股份有限公司 | 一种ⅰ型阿托伐他汀钙的纯化方法 |
CN104983702A (zh) * | 2015-07-23 | 2015-10-21 | 青岛蓝盛洋医药生物科技有限责任公司 | 一种治疗高胆固醇血症的药物阿托伐他汀钙组合物片剂 |
US10450957B2 (en) | 2017-01-23 | 2019-10-22 | United Technologies Corporation | Gas turbine engine with heat pipe system |
EP3822249A4 (en) * | 2018-07-13 | 2022-04-13 | Kyowa Hakko Bio Co., Ltd. | CRYSTAL OF EUCOMIC ACID NONSOLVATE AND METHOD OF PREPARATION THEREOF |
Family Cites Families (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4681893A (en) | 1986-05-30 | 1987-07-21 | Warner-Lambert Company | Trans-6-[2-(3- or 4-carboxamido-substituted pyrrol-1-yl)alkyl]-4-hydroxypyran-2-one inhibitors of cholesterol synthesis |
US5216174A (en) | 1988-02-22 | 1993-06-01 | Warner-Lambert Co. | Process for trans-6-[12-(substituted-pyrrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis |
US5003080A (en) | 1988-02-22 | 1991-03-26 | Warner-Lambert Company | Process for trans-6-(2-(substituted-pyrrol-1-yl)alkyl)pryan-2-one inhibitors of cholesterol synthesis |
US5245047A (en) | 1988-02-22 | 1993-09-14 | Warner-Lambert Company | Process for trans-6-[2-(substituted-pyrrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis |
US5097045A (en) | 1989-02-01 | 1992-03-17 | Warner-Lambert Company | Process for trans-6-[2-(substituted-pyrrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis |
US5149837A (en) | 1988-02-22 | 1992-09-22 | Warner-Lambert Company | Process for trans-6-[2-(substituted-pyrrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis |
US5124482A (en) | 1988-02-22 | 1992-06-23 | Warner-Lambert Company | Process for trans-6-(2-substituted-pyrrol-1-yl)alkyl)pyran-2-one inhibitors of cholesterol synthesis |
FI94339C (fi) | 1989-07-21 | 1995-08-25 | Warner Lambert Co | Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi |
US5103024A (en) | 1990-10-17 | 1992-04-07 | Warner-Lambert Company | Process for the synthesis of (4r-cis)-1,1-dimethylethyl 6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate |
US5248793A (en) | 1990-10-17 | 1993-09-28 | Warner-Lambert Company | Process for the synthesis of (4R-cis)-1,1-dimethylethyl 6-iodomethyl or 6-(phenyl-substituted)sulfonyloxymethyl-2,2-dimethyl-1,3-dioxane-4-acetate |
US5155251A (en) | 1991-10-11 | 1992-10-13 | Warner-Lambert Company | Process for the synthesis of (5R)-1,1-dimethylethyl-6-cyano-5-hydroxy-3-oxo-hexanoate |
ATE178794T1 (de) | 1993-01-19 | 1999-04-15 | Warner Lambert Co | Stabilisierte, oral anzuwendende zusammensetzung enthaltend die verbindung ci-981 und verfahren |
US5298627A (en) | 1993-03-03 | 1994-03-29 | Warner-Lambert Company | Process for trans-6-[2-(substituted-pyrrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis |
HRP960313B1 (en) | 1995-07-17 | 2002-08-31 | Warner Lambert Co | Form iii crystalline (r- (r*, r*)-2- (4-fluorophenyl) -beta-delta-hydroxy-5-(1-methylethyl) -3-phenyl-4- ((phenylamino) carbonyl -1h-pyrrole-1-heptanoic acid calcium salt (2:1) |
BR9609872A (pt) | 1995-07-17 | 1999-03-23 | Warner Lambert Co | Hemi sal de cálcio de ácido (R-(R*R*)]-2-(4-fluorfenil-)-beta delta-diidróxi-5-(1-metiletil)-3-fenil-4- [(fenilamino) carbonil]-1H- pirrol-1heptanóico (atorvasta-tina)c ristalino |
HRP960312B1 (en) * | 1995-07-17 | 2001-10-31 | Warner Lambert Co | NOVEL PROCESS FOR THE PRODUCTION OF AMORPHOUS /R-(R*, R*)/-2-(4-FLUOROPHENYL)-"beta", "delta"-DIHYDROXY-5-PHENYL-4-/(PHENYLAMINO)CARBONYL/-1H-PYRROLE -1-HEPTANOIC ACID CALCIUM SALT (2 : 1) |
US6087511A (en) | 1996-07-16 | 2000-07-11 | Warner-Lambert Company | Process for the production of amorphous [R-(R*,R*)]-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl )-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid) calcium salt (2:1) |
TR199900191T2 (xx) | 1996-07-29 | 1999-04-21 | Warner-Lambert Company | (S)-3,4-Dihidroksibutirik asitin korumal� esterlerinin sentezi i�in geli�tirilmi� proses. |
IN191236B (es) * | 1999-05-25 | 2003-10-11 | Ranbaxy Lab Ltd | |
US7411075B1 (en) * | 2000-11-16 | 2008-08-12 | Teva Pharmaceutical Industries Ltd. | Polymorphic form of atorvastatin calcium |
ATE288893T1 (de) * | 1999-11-17 | 2005-02-15 | Teva Pharma | Polymorphe form von atorvastatin-calcium |
SI20425A (sl) | 1999-12-10 | 2001-06-30 | LEK tovarna farmacevtskih in kemi�nih izdelkov d.d. | Priprava amorfnega atorvastatina |
EP1242373B1 (en) * | 1999-12-17 | 2006-03-15 | Pfizer Science and Technology Ireland Limited | A process for producing crystalline atorvastatin calcium |
HUP0203708A3 (en) * | 1999-12-17 | 2003-11-28 | Warner Lambert Res & Dev Ie | A factory scale process for producing crystalline atorvastatin trihydrate hemi calcium salt |
CN1535139A (zh) * | 2000-11-03 | 2004-10-06 | ������ҩ��ҵ����˾ | 阿伐他丁半钙形式ⅶ |
KR100877165B1 (ko) | 2000-11-16 | 2009-01-07 | 테바 파마슈티컬 인더스트리즈 리미티드 | 수산화 칼슘을 이용한[R(R*,R*)]-2-(4-플루오로페닐)-β,δ-디하이드록시-5-(1-메틸에틸)-3-페닐-4-[(페닐아미노)카보닐]-1H-피롤-1-헵탄산 에스테르의 가수분해 |
US7501450B2 (en) * | 2000-11-30 | 2009-03-10 | Teva Pharaceutical Industries Ltd. | Crystal forms of atorvastatin hemi-calcium and processes for their preparation as well as novel processes for preparing other forms |
IL156055A0 (en) * | 2000-11-30 | 2003-12-23 | Teva Pharma | Novel crystal forms of atorvastatin hemi calcium and processes for their preparation as well as novel processes for preparing other forms |
MXPA03005879A (es) * | 2000-12-27 | 2003-09-10 | Ciba Sc Holding Ag | Formas cristalinas de atorvastatina. |
WO2002057228A1 (en) | 2001-01-17 | 2002-07-25 | Biocon India Limited | Atorvastatin calcium |
WO2002057229A1 (en) | 2001-01-19 | 2002-07-25 | Biocon India Limited | FORM V CRYSTALLINE [R-(R*,R*)]-2-(4-FLUOROPHENYL)-ß,$G(D)-DIHYDROXY-5-(1-METHYLETHYL)-3-PHENYL-4-[(PHENYLAMINO)CARBONYL]-1H-PYRROLE-1- HEPTANOIC ACID HEMI CALCIUM SALT. (ATORVASTATIN) |
SI20814A (sl) | 2001-01-23 | 2002-08-31 | LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. | Priprava amorfnega atorvastatina |
SI20848A (sl) | 2001-03-14 | 2002-10-31 | Lek, Tovarna Farmacevtskih In Kemijskih Izdelkov, D.D. | Farmacevtska formulacija, ki vsebuje atorvastatin kalcij |
IN190564B (es) | 2001-04-11 | 2003-08-09 | Cadila Heathcare Ltd | |
GB0111077D0 (en) | 2001-05-04 | 2001-06-27 | Biochemie Gmbh | Organic compounds |
AP1571A (en) * | 2001-06-29 | 2006-02-10 | Warner Lambert Co | Crystalline forms of 'R-(R* ,R*)!-2-(4- fluorophenyl)-beta, delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-'phenylamino)carbonyl!-1H-pyrrole-1-heptanoic acid calcium salt (2:1) (atorvastatin) |
US7074818B2 (en) * | 2001-07-30 | 2006-07-11 | Dr. Reddy's Laboratories Limited | Crystalline forms VI and VII of Atorvastatin calcium |
KR20100023059A (ko) * | 2005-12-13 | 2010-03-03 | 테바 파마슈티컬 인더스트리즈 리미티드 | 아토바스타틴 헤미칼슘의 결정형 및 이의 제조 방법 |
US20070265456A1 (en) * | 2006-05-09 | 2007-11-15 | Judith Aronhime | Novel crystal forms of atorvastatin hemi-calcium and processes for their preparation as well as novel processes for preparing other forms |
-
2002
- 2002-05-21 AP APAP/P/2003/002936A patent/AP1571A/en active
- 2002-05-21 PL PL02367943A patent/PL367943A1/xx not_active Application Discontinuation
- 2002-05-21 NZ NZ529557A patent/NZ529557A/en unknown
- 2002-05-21 CA CA002450111A patent/CA2450111C/en not_active Expired - Fee Related
- 2002-05-21 WO PCT/IB2002/001796 patent/WO2003004470A1/en active Application Filing
- 2002-05-21 GE GE5360A patent/GEP20053546B/en unknown
- 2002-05-21 EP EP02727946.2A patent/EP1423364B1/en not_active Expired - Lifetime
- 2002-05-21 JP JP2003510638A patent/JP3965155B2/ja not_active Expired - Fee Related
- 2002-05-21 SK SK1600-2003A patent/SK16002003A3/sk unknown
- 2002-05-21 CZ CZ20033478A patent/CZ20033478A3/cs unknown
- 2002-05-21 CN CNA2007101598559A patent/CN101215253A/zh active Pending
- 2002-05-21 OA OA1200300342A patent/OA12636A/en unknown
- 2002-05-21 AU AU2002258092A patent/AU2002258092B2/en not_active Ceased
- 2002-05-21 BR BR0210666-3A patent/BR0210666A/pt not_active IP Right Cessation
- 2002-05-21 RS YUP-1000/03A patent/RS100003A/sr unknown
- 2002-05-21 MX MXPA03010266A patent/MXPA03010266A/es active IP Right Grant
- 2002-05-21 EP EP15192682.1A patent/EP3009423A3/en not_active Withdrawn
- 2002-05-21 EE EEP200300597A patent/EE200300597A/xx unknown
- 2002-05-21 ES ES02727946.2T patent/ES2558565T3/es not_active Expired - Lifetime
- 2002-05-21 CN CNA028130227A patent/CN1524073A/zh active Pending
- 2002-05-21 UA UA20031212658A patent/UA74075C2/uk unknown
- 2002-05-21 EA EA200301243A patent/EA005317B1/ru not_active IP Right Cessation
- 2002-05-21 IL IL15879002A patent/IL158790A0/xx unknown
- 2002-05-21 KR KR1020037016944A patent/KR100609371B1/ko not_active IP Right Cessation
- 2002-05-21 HU HU0400381A patent/HUP0400381A2/hu unknown
- 2002-06-05 DO DO2002000413A patent/DOP2002000413A/es unknown
- 2002-06-26 PE PE2002000569A patent/PE20030124A1/es not_active Application Discontinuation
- 2002-06-27 UY UY27359A patent/UY27359A1/es not_active Application Discontinuation
- 2002-06-28 SV SV2002001144A patent/SV2003001144A/es not_active Application Discontinuation
- 2002-06-28 MY MYPI20022466A patent/MY122907A/en unknown
- 2002-06-28 TW TW091114336A patent/TWI319396B/zh not_active IP Right Cessation
- 2002-06-28 PA PA20028549501A patent/PA8549501A1/es unknown
- 2002-06-28 US US10/184,669 patent/US6605729B1/en not_active Expired - Lifetime
- 2002-06-28 AR ARP020102428A patent/AR036118A1/es unknown
-
2003
- 2003-06-06 US US10/456,046 patent/US7144915B2/en not_active Expired - Lifetime
- 2003-07-08 TN TNPCT/IB2002/001796A patent/TNSN03147A1/fr unknown
- 2003-11-10 ZA ZA200308731A patent/ZA200308731B/en unknown
- 2003-11-26 CR CR7170A patent/CR7170A/es not_active Application Discontinuation
- 2003-11-28 BG BG108393A patent/BG108393A/bg unknown
- 2003-12-16 HR HR20031039A patent/HRP20031039A2/xx not_active Application Discontinuation
- 2003-12-18 NO NO20035675A patent/NO326170B1/no unknown
- 2003-12-22 MA MA27456A patent/MA27044A1/fr unknown
- 2003-12-29 EC EC2003004928A patent/ECSP034928A/es unknown
-
2006
- 2006-05-25 US US11/441,268 patent/US20060241169A1/en not_active Abandoned
-
2007
- 2007-04-11 JP JP2007103465A patent/JP2007182460A/ja active Pending
- 2007-10-25 US US11/977,459 patent/US20080214651A1/en not_active Abandoned
-
2008
- 2008-02-15 CR CR9741A patent/CR9741A/es not_active Application Discontinuation
- 2008-07-14 US US12/172,503 patent/US20080287521A1/en not_active Abandoned
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SV2003001144A (es) | FORMAS CRISTALINAS DE LA SAL DE CALCIO DEL ACIDO [R-(R*,R*)]-2-(4-FLUOROFENIL)-ß,ô-DIHIDROXI-5-(1-METILETIL)-3-FENIL-4[(FENILAMINO)CARBONIL]-1H-PIRROL-1-HEPTANOICO (2:1) REF. PC430-01FJT | |
IL173059A0 (en) | (2s,4s)-4-fluoro-1-[4-fluoro-beta-(4-fluorophenyl)-l-phenylalanyl]-2-pyrrolidinecarbonitrile p-toluenesulfonic acid salt and anhydrous crystalline forms thereof | |
ATE455092T1 (de) | Substituierte tetracyclin-verbindungen zur behandlung von malaria | |
DK1449917T3 (da) | Fremgangsmåde til L-aminosyrefremstilling under anvendelse af Escherichia | |
PT1671949E (pt) | Piridinilaminas substituídas | |
NO20041917D0 (no) | Spesifikke midler som binder humant angiopoietin-2 | |
RS50091B (sr) | Upotreba retigabina u lečenju neuropatskog bola | |
SE0100901D0 (sv) | New composition | |
ATE396199T1 (de) | Antimikrobielles polypeptid | |
ITVR940019A0 (it) | Attrezzo ortopedico, particolarmente per la correzione graduale ester-na di fratture. | |
ECSP055584A (es) | Proceso para la preparación de fibrinógeno | |
EA200301142A1 (ru) | Производные гетероциклилокси-, -тиокси- и -аминобензазола в качестве лигандов 5-гидрокситриптамина-6 | |
SE9802729D0 (sv) | Novel Compounds | |
DK1097173T3 (da) | Anvendelse af peptider af IL-2 og derivater deraf som terapeutiske midler | |
DE60218064D1 (de) | Neues peptid mit angiotensinkonvertase hemmender wirkung | |
CY1107230T1 (el) | Υποκατεστημενες ενωσεις 1-φαιναιθυλοπιπεριδινης, οι οποιες μεταξυ αλλων χρησιμοποιουνται σαν αναλγητικα | |
ATE433458T1 (de) | Modulatoren von ship-1 | |
EA200300727A1 (ru) | Производные 2h-1-бензопирана, способы их получения и их фармацевтические композиции | |
NO20051301L (no) | Proteintyrosinforfataseinhibitorer | |
EA200400392A1 (ru) | Связывающий каспазу-8 белок, его получение и применение | |
ATE280776T1 (de) | Medizinische verwendung von mechanismus- orientierten inhibitoren der dipeptidylpeptidase i | |
WO2002024181A3 (en) | The use of melatonin for induction of general anesthesia | |
MXPA04000272A (es) | Derivados de 4-aminociclohexanol sustituidos. | |
ATE391489T1 (de) | Haarbehandlungszusammensetzungen | |
EA200400661A1 (ru) | Фенилалкины |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD | Lapse |