ECSP055584A - Proceso para la preparación de fibrinógeno - Google Patents
Proceso para la preparación de fibrinógenoInfo
- Publication number
- ECSP055584A ECSP055584A EC2005005584A ECSP055584A ECSP055584A EC SP055584 A ECSP055584 A EC SP055584A EC 2005005584 A EC2005005584 A EC 2005005584A EC SP055584 A ECSP055584 A EC SP055584A EC SP055584 A ECSP055584 A EC SP055584A
- Authority
- EC
- Ecuador
- Prior art keywords
- preparation process
- fibrinogen preparation
- fibrinogen
- purification
- processes
- Prior art date
Links
- 102000008946 Fibrinogen Human genes 0.000 title abstract 3
- 108010049003 Fibrinogen Proteins 0.000 title abstract 3
- 229940012952 fibrinogen Drugs 0.000 title abstract 3
- 238000002360 preparation method Methods 0.000 title abstract 2
- FBPFZTCFMRRESA-ZXXMMSQZSA-N D-iditol Chemical compound OC[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-ZXXMMSQZSA-N 0.000 title 1
- 238000000034 method Methods 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/75—Fibrinogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Analytical Chemistry (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La presente invención describe el uso de cromatografía de afinidad de iones metálicos inmovilizados para la separación de fibrinógeno de plasminógeno, para la purificación de fibrinógeno y por lo menos otra proteína, por ejemplo plasminógeno, y para la co-purificación de fibrinógeno y el factor XIII.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0216001.8A GB0216001D0 (en) | 2002-07-10 | 2002-07-10 | Process and composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP055584A true ECSP055584A (es) | 2005-07-06 |
Family
ID=9940203
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EC2005005584A ECSP055584A (es) | 2002-07-10 | 2005-02-02 | Proceso para la preparación de fibrinógeno |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US7816495B2 (es) |
| EP (1) | EP1519944B1 (es) |
| JP (1) | JP4324102B2 (es) |
| AT (1) | ATE449104T1 (es) |
| AU (1) | AU2003244850B2 (es) |
| BR (1) | BRPI0312521B8 (es) |
| CA (1) | CA2491716C (es) |
| DE (1) | DE60330146D1 (es) |
| DK (1) | DK1519944T3 (es) |
| EC (1) | ECSP055584A (es) |
| ES (1) | ES2332780T3 (es) |
| GB (1) | GB0216001D0 (es) |
| IL (1) | IL165988A0 (es) |
| MX (1) | MXPA05000395A (es) |
| NO (1) | NO20050091L (es) |
| PL (1) | PL210616B1 (es) |
| WO (1) | WO2004007533A1 (es) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004009400A1 (de) * | 2004-02-24 | 2005-09-08 | Zlb Behring Gmbh | Fibrinogen Reinigung |
| DE102004037805B3 (de) * | 2004-08-03 | 2006-03-23 | Zlb Behring Gmbh | Verfahren zur Hitzebehandlung fibrinogenhaltiger pharmazeutischer Zubereitungen |
| WO2006021584A2 (en) | 2004-08-27 | 2006-03-02 | Novo Nordisk Health Care Ag | Purification of factor xiii polypeptides from biological materials |
| JP5086093B2 (ja) * | 2004-11-23 | 2012-11-28 | ジモジェネティクス、インコーポレイテッド | 組換え型ヒトxiii因子の精製 |
| FR2887883B1 (fr) | 2005-06-29 | 2007-08-31 | Lab Francais Du Fractionnement | Procede de separation des proteines fibrinogene, facteur xiii et colle biologique d'une fraction plasmatique solubilisee et de preparation de concentres lyophilises desdites proteines |
| CN101067131B (zh) * | 2007-04-30 | 2011-08-17 | 华南理工大学 | 一种利用亲和层析法分离纯化纤溶酶的方法 |
| WO2009130181A2 (en) * | 2008-04-21 | 2009-10-29 | Novo Nordisk Health Care Ag | Dry transglutaminase composition |
| US8945895B2 (en) | 2009-07-31 | 2015-02-03 | Baxter International Inc. | Methods of purifying recombinant ADAMTS13 and other proteins and compositions thereof |
| CN106046147B (zh) | 2010-09-20 | 2019-11-19 | 欧克塔医药公司 | 纤维蛋白原生产方法 |
| EP2825555B1 (en) | 2012-03-13 | 2017-07-12 | Octapharma AG | Mproved process for production of fibrinogen and fibrinogen produced thereby |
| US9243239B2 (en) | 2012-03-26 | 2016-01-26 | The Regents Of The University Of Colorado, A Body Corporate | Purification of cystathionine beta-synthase |
| US20140154233A1 (en) | 2012-12-05 | 2014-06-05 | Csl Limited | Method of purifying therapeutic proteins |
| US10188965B2 (en) | 2012-12-05 | 2019-01-29 | Csl Behring Gmbh | Hydrophobic charge induction chromatographic depletion of a protein from a solution |
| US9675678B2 (en) | 2013-01-29 | 2017-06-13 | The Regents Of The University Of Colorado, A Body Corporate | Compositions and methods for treatment of homocystinuria |
| US9932388B2 (en) | 2014-11-13 | 2018-04-03 | Hemarus Therapeutics Limited | Chromatographic process for producing high purity fibrinogen and thrombin |
| AU2016354030B2 (en) | 2015-11-09 | 2022-09-15 | The Regents Of The University Of Colorado, A Body Corporate | Compositions and methods for treatment of homocystinuria |
| US10695395B2 (en) * | 2015-12-23 | 2020-06-30 | Phoenix Tissue Repair, Inc. | Collagen 7 compositions and methods of using the same |
| MX2019012347A (es) | 2017-04-17 | 2020-01-15 | Univ Colorado Regents | Optimizacion de terapia de reemplazo enzimatico para el tratamiento de la homocistinuria. |
| SG11202003793WA (en) | 2017-10-30 | 2020-05-28 | Baxalta GmbH | Environmentally compatible detergents for inactivation of lipid-enveloped viruses |
| CN116744986A (zh) | 2020-12-25 | 2023-09-12 | 广州倍绣生物技术有限公司 | 纤维蛋白原除菌过滤 |
| US20240342253A1 (en) | 2021-08-13 | 2024-10-17 | Biotest Ag | Fibrinogen compositions and methods of preparation |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2618784B1 (fr) | 1987-07-30 | 1990-04-06 | Lille Transfusion Sanguine | Concentre de proteines coagulables par la thrombine, son procede d'obtention et son utilisation a titre de colle biologique |
| US5445958A (en) | 1987-12-22 | 1995-08-29 | National Blood Authority | Process for purifying blood clotting factors |
| JPH02193913A (ja) | 1989-01-20 | 1990-07-31 | Denki Kagaku Kogyo Kk | パイロジエンを除去する方法 |
| US5169936A (en) | 1989-04-14 | 1992-12-08 | Biogen, Inc. | Protein purification on immobilized metal affinity resins effected by elution using a weak ligand |
| US5792835A (en) | 1991-09-05 | 1998-08-11 | Baxter International Inc. | Method of preparing a topical fibrinogen complex |
| WO1994002183A1 (en) | 1992-07-27 | 1994-02-03 | Haemacure Biotech Inc. | Biocompatible surgical implant |
| JPH06138127A (ja) | 1992-10-26 | 1994-05-20 | Tanabe Seiyaku Co Ltd | 標識フィブリノーゲンおよびその用途 |
| US5395923A (en) | 1993-02-23 | 1995-03-07 | Haemacure-Biotech, Inc. | Process for the obtention of a biological adhesive made of concentrated coagulation factors by "salting-out" |
| AU695266B2 (en) | 1994-03-18 | 1998-08-13 | Baxter International Inc. | Topical fibrinogen complex |
| JPH0812586A (ja) | 1994-07-01 | 1996-01-16 | Mikimoto Pharmaceut Co Ltd | 抗プラスミン剤 |
| GB9424732D0 (en) | 1994-12-08 | 1995-02-08 | Common Services Agency | Heat treated blood plasma proteins |
| JPH08333387A (ja) | 1995-06-12 | 1996-12-17 | Mitsubishi Materials Corp | タンパク質分離精製方法 |
| US6268487B1 (en) | 1996-05-13 | 2001-07-31 | Genzyme Transgenics Corporation | Purification of biologically active peptides from milk |
| GB9722131D0 (en) | 1997-10-20 | 1997-12-17 | Medical Res Council | Method |
| US5981254A (en) | 1997-10-30 | 1999-11-09 | Haemacure Corporation | Process for producing thrombin from plasma |
| AUPP521298A0 (en) | 1998-08-12 | 1998-09-03 | Life Therapeutics Limited | Purification of fibrinogen |
| JP2001270900A (ja) | 2000-03-23 | 2001-10-02 | Nihon Pharmaceutical Co Ltd | フィブリノゲンのウイルス不活化法 |
-
2002
- 2002-07-10 GB GBGB0216001.8A patent/GB0216001D0/en not_active Ceased
-
2003
- 2003-07-07 WO PCT/GB2003/002928 patent/WO2004007533A1/en not_active Ceased
- 2003-07-07 AU AU2003244850A patent/AU2003244850B2/en not_active Expired
- 2003-07-07 EP EP03738326A patent/EP1519944B1/en not_active Expired - Lifetime
- 2003-07-07 DK DK03738326.2T patent/DK1519944T3/da active
- 2003-07-07 JP JP2004520819A patent/JP4324102B2/ja not_active Expired - Lifetime
- 2003-07-07 MX MXPA05000395A patent/MXPA05000395A/es active IP Right Grant
- 2003-07-07 ES ES03738326T patent/ES2332780T3/es not_active Expired - Lifetime
- 2003-07-07 BR BRPI0312521A patent/BRPI0312521B8/pt not_active IP Right Cessation
- 2003-07-07 US US10/520,436 patent/US7816495B2/en not_active Expired - Lifetime
- 2003-07-07 PL PL374080A patent/PL210616B1/pl unknown
- 2003-07-07 DE DE60330146T patent/DE60330146D1/de not_active Expired - Lifetime
- 2003-07-07 CA CA2491716A patent/CA2491716C/en not_active Expired - Lifetime
- 2003-07-07 AT AT03738326T patent/ATE449104T1/de active
-
2004
- 2004-12-26 IL IL16598804A patent/IL165988A0/xx unknown
-
2005
- 2005-01-06 NO NO20050091A patent/NO20050091L/no unknown
- 2005-02-02 EC EC2005005584A patent/ECSP055584A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL210616B1 (pl) | 2012-02-29 |
| AU2003244850B2 (en) | 2009-06-25 |
| US20070042944A1 (en) | 2007-02-22 |
| US7816495B2 (en) | 2010-10-19 |
| JP2006505508A (ja) | 2006-02-16 |
| BRPI0312521B8 (pt) | 2021-05-25 |
| IL165988A0 (en) | 2006-01-15 |
| MXPA05000395A (es) | 2005-09-30 |
| DE60330146D1 (de) | 2009-12-31 |
| NO20050091L (no) | 2005-04-06 |
| WO2004007533A1 (en) | 2004-01-22 |
| PL374080A1 (en) | 2005-09-19 |
| BRPI0312521B1 (pt) | 2019-06-25 |
| ATE449104T1 (de) | 2009-12-15 |
| CA2491716C (en) | 2012-02-07 |
| JP4324102B2 (ja) | 2009-09-02 |
| EP1519944B1 (en) | 2009-11-18 |
| EP1519944A1 (en) | 2005-04-06 |
| CA2491716A1 (en) | 2004-01-22 |
| BR0312521A (pt) | 2005-04-19 |
| DK1519944T3 (da) | 2010-03-29 |
| GB0216001D0 (en) | 2002-08-21 |
| AU2003244850A1 (en) | 2004-02-02 |
| ES2332780T3 (es) | 2010-02-12 |
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