SMT202200447T1 - Composizioni oftalmiche comprendenti un antagonista muscarinico e acqua deuterata - Google Patents
Composizioni oftalmiche comprendenti un antagonista muscarinico e acqua deuterataInfo
- Publication number
- SMT202200447T1 SMT202200447T1 SM20220447T SMT202200447T SMT202200447T1 SM T202200447 T1 SMT202200447 T1 SM T202200447T1 SM 20220447 T SM20220447 T SM 20220447T SM T202200447 T SMT202200447 T SM T202200447T SM T202200447 T1 SMT202200447 T1 SM T202200447T1
- Authority
- SM
- San Marino
- Prior art keywords
- ophthalmic compositions
- muscarinic antagonist
- deuterated water
- deuterated
- water
- Prior art date
Links
- XLYOFNOQVPJJNP-ZSJDYOACSA-N Heavy water Chemical compound [2H]O[2H] XLYOFNOQVPJJNP-ZSJDYOACSA-N 0.000 title 1
- 229940121948 Muscarinic receptor antagonist Drugs 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 239000003149 muscarinic antagonist Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Inorganic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462016502P | 2014-06-24 | 2014-06-24 | |
| US201462096433P | 2014-12-23 | 2014-12-23 | |
| US201562151926P | 2015-04-23 | 2015-04-23 | |
| US14/726,139 US9421199B2 (en) | 2014-06-24 | 2015-05-29 | Ophthalmic composition |
| EP15811865.3A EP3160471B1 (en) | 2014-06-24 | 2015-06-23 | Ophthalmic compositions comprising a muscarinic antagonist and deuterated water |
| PCT/US2015/037249 WO2015200361A1 (en) | 2014-06-24 | 2015-06-23 | Ophthalmic composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SMT202200447T1 true SMT202200447T1 (it) | 2023-01-13 |
Family
ID=54868660
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SM20220447T SMT202200447T1 (it) | 2014-06-24 | 2015-06-23 | Composizioni oftalmiche comprendenti un antagonista muscarinico e acqua deuterata |
Country Status (23)
| Country | Link |
|---|---|
| US (12) | US9421199B2 (enExample) |
| EP (3) | EP4115884A1 (enExample) |
| JP (5) | JP6678362B2 (enExample) |
| KR (4) | KR20240144477A (enExample) |
| CN (3) | CN110638749A (enExample) |
| BR (1) | BR112016030368B1 (enExample) |
| CA (1) | CA2953363C (enExample) |
| DK (1) | DK3160471T3 (enExample) |
| ES (1) | ES2924243T3 (enExample) |
| FI (1) | FIC20250034I1 (enExample) |
| HR (1) | HRP20220972T1 (enExample) |
| HU (1) | HUE059521T2 (enExample) |
| IL (1) | IL249643B (enExample) |
| LT (1) | LT3160471T (enExample) |
| NO (1) | NO2025049I1 (enExample) |
| PL (1) | PL3160471T3 (enExample) |
| PT (1) | PT3160471T (enExample) |
| RS (1) | RS63486B1 (enExample) |
| SG (3) | SG11201610682UA (enExample) |
| SI (1) | SI3160471T1 (enExample) |
| SM (1) | SMT202200447T1 (enExample) |
| TW (4) | TWI763620B (enExample) |
| WO (1) | WO2015200361A1 (enExample) |
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| HRP20230559T1 (hr) | 2012-08-24 | 2023-09-15 | Sun Pharmaceutical Industries Limited | Oftalmička formulacija polioksil lipida ili polioksil masne kiseline i tretman očnih stanja |
| WO2016172712A2 (en) | 2015-04-23 | 2016-10-27 | Sydnexis, Inc. | Ophthalmic composition |
| US9421199B2 (en) | 2014-06-24 | 2016-08-23 | Sydnexis, Inc. | Ophthalmic composition |
| US10010502B2 (en) | 2015-05-19 | 2018-07-03 | Amorphex Therapeutics Llc | Device that delivers a sustained low-dose of a myopia-suppressing drug, while preserving pupillary function and accommodation |
| WO2016196367A1 (en) * | 2015-05-29 | 2016-12-08 | Sydnexis, Inc. | D2o stabilized pharmaceutical formulations |
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| DK3423076T3 (da) | 2016-02-29 | 2024-07-08 | Sun Pharmaceutical Ind Ltd | Topisk cyclosporinholdige formuleringer og anvendelser deraf |
| WO2017177262A1 (en) | 2016-04-11 | 2017-10-19 | University Of Canberra | Ophthalmic compositions comprising levodopa, an antioxidant and an aqueous carrier |
| KR102580933B1 (ko) * | 2016-05-25 | 2023-09-19 | 싱가포르 헬스 서비시즈 피티이 엘티디 | 아트로핀-함유 수성 조성물 |
| AU2018224426B2 (en) * | 2017-02-21 | 2023-05-18 | Singapore Health Services Pte Ltd | Composition and method for preventing or delaying onset of myopia comprising atropine |
| SG11201907315PA (en) * | 2017-03-23 | 2019-09-27 | Singapore Health Serv Pte Ltd | Agent for preventing myopia, treating myopia, and/or preventing myopia progression comprising tiotropium as active ingredient |
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| US20220288114A1 (en) * | 2019-07-11 | 2022-09-15 | University Of Utah Research Foundation | Multi-agent ocular formulations and treatment methods |
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| EP4489858A1 (en) * | 2022-03-07 | 2025-01-15 | Harrow IP, LLC | Extended-release pharmaceutical compositions for treating eye conditions |
| WO2023171989A1 (ko) * | 2022-03-11 | 2023-09-14 | 주식회사 메디치바이오 | 안질환 예방 또는 치료용 약학 조성물 |
| CN119730856A (zh) * | 2022-05-03 | 2025-03-28 | 艾威药业公司 | 二异丙基膦酰烷作为局部药物用于治疗眼部疾病 |
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| US20240033260A1 (en) * | 2022-07-26 | 2024-02-01 | The Chinese University Of Hong Kong | Low-concentration atropine for myopia prevention (lamp-2) study |
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