SK7212002A3 - 1-(2'-aminoacyl)-2-cyanopyrrolidine derivatives, pharmaceutical compositions containing same and use - Google Patents

1-(2'-aminoacyl)-2-cyanopyrrolidine derivatives, pharmaceutical compositions containing same and use Download PDF

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Publication number
SK7212002A3
SK7212002A3 SK721-2002A SK7212002A SK7212002A3 SK 7212002 A3 SK7212002 A3 SK 7212002A3 SK 7212002 A SK7212002 A SK 7212002A SK 7212002 A3 SK7212002 A3 SK 7212002A3
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SK
Slovakia
Prior art keywords
compound
alkyl
pyrrolidine
carbonitrile
group
Prior art date
Application number
SK721-2002A
Other languages
English (en)
Slovak (sk)
Inventor
David Michael Evans
Original Assignee
Ferring Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferring Bv filed Critical Ferring Bv
Publication of SK7212002A3 publication Critical patent/SK7212002A3/sk

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
SK721-2002A 1999-11-30 2000-11-30 1-(2'-aminoacyl)-2-cyanopyrrolidine derivatives, pharmaceutical compositions containing same and use SK7212002A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9928330.1A GB9928330D0 (en) 1999-11-30 1999-11-30 Novel antidiabetic agents
PCT/GB2000/004572 WO2001040180A2 (en) 1999-11-30 2000-11-30 N-substituted 2-cyanopyrrolidines and their use as antidiabetic agents

Publications (1)

Publication Number Publication Date
SK7212002A3 true SK7212002A3 (en) 2002-12-03

Family

ID=10865461

Family Applications (1)

Application Number Title Priority Date Filing Date
SK721-2002A SK7212002A3 (en) 1999-11-30 2000-11-30 1-(2'-aminoacyl)-2-cyanopyrrolidine derivatives, pharmaceutical compositions containing same and use

Country Status (23)

Country Link
US (2) US6911467B2 (pt)
EP (1) EP1351932A2 (pt)
JP (1) JP2003515585A (pt)
KR (1) KR20020063185A (pt)
CN (1) CN1192020C (pt)
AU (1) AU781060B2 (pt)
BR (1) BR0015788A (pt)
CA (1) CA2392713A1 (pt)
CZ (1) CZ20021520A3 (pt)
EE (1) EE200200273A (pt)
GB (1) GB9928330D0 (pt)
HR (1) HRP20020421B1 (pt)
HU (1) HUP0203700A3 (pt)
IL (2) IL149359A0 (pt)
MX (1) MXPA02005253A (pt)
MY (1) MY131036A (pt)
NO (1) NO20022502L (pt)
PL (1) PL355333A1 (pt)
RU (1) RU2265012C2 (pt)
SK (1) SK7212002A3 (pt)
UA (1) UA75341C2 (pt)
WO (1) WO2001040180A2 (pt)
ZA (1) ZA200204283B (pt)

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US6172081B1 (en) 1999-06-24 2001-01-09 Novartis Ag Tetrahydroisoquinoline 3-carboxamide derivatives

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HRP20020421B1 (en) 2008-01-31
ZA200204283B (en) 2003-09-03
BR0015788A (pt) 2002-07-16
AU1538401A (en) 2001-06-12
HUP0203700A3 (en) 2004-01-28
CN1192020C (zh) 2005-03-09
US6911467B2 (en) 2005-06-28
NO20022502D0 (no) 2002-05-27
EP1351932A2 (en) 2003-10-15
US7169806B2 (en) 2007-01-30
CZ20021520A3 (cs) 2002-10-16
HUP0203700A2 (hu) 2003-03-28
EE200200273A (et) 2003-06-16
IL149359A0 (en) 2002-11-10
MY131036A (en) 2007-07-31
CN1402706A (zh) 2003-03-12
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US20030096857A1 (en) 2003-05-22
WO2001040180A2 (en) 2001-06-07
US20050203031A1 (en) 2005-09-15
KR20020063185A (ko) 2002-08-01
JP2003515585A (ja) 2003-05-07
IL149359A (en) 2007-10-31
RU2265012C2 (ru) 2005-11-27
MXPA02005253A (es) 2002-11-07
CA2392713A1 (en) 2001-06-07
UA75341C2 (en) 2006-04-17
NO20022502L (no) 2002-05-27

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