SK287463B6 - N-(2-aryletyl)benzylamíny ako antagonisty receptora 5-HT6 - Google Patents

N-(2-aryletyl)benzylamíny ako antagonisty receptora 5-HT6 Download PDF

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Publication number
SK287463B6
SK287463B6 SK1205-2003A SK12052003A SK287463B6 SK 287463 B6 SK287463 B6 SK 287463B6 SK 12052003 A SK12052003 A SK 12052003A SK 287463 B6 SK287463 B6 SK 287463B6
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Slovakia
Prior art keywords
ethyl
indol
benzylamine
methoxy
phenoxybenzylamine
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SK1205-2003A
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English (en)
Slovak (sk)
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SK12052003A3 (sk
Inventor
Zhaogen Chen
Michael Philip Cohen
Matthew Joseph Fisher
Bruno Giethlen
James Ronald Gillig
Jefferson Ray Mccowan
Shawn Christopher Miller
John Mehnert Schaus
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Eli Lilly And Company
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Publication of SK12052003A3 publication Critical patent/SK12052003A3/sk
Publication of SK287463B6 publication Critical patent/SK287463B6/sk

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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
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    • C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
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    • C07C317/34—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring
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    • C07C323/32—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton having at least one of the nitrogen atoms bound to an acyclic carbon atom of the carbon skeleton
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PL220721B1 (pl) 2015-12-31
DK1379239T3 (da) 2008-01-07
DZ3493A1 (fr) 2002-10-10
BR0208179A (pt) 2004-03-02
US20060009511A9 (en) 2006-01-12
US20040132800A1 (en) 2004-07-08
SI1859798T1 (sl) 2016-07-29
PL364458A1 (en) 2004-12-13
HRP20030771A2 (en) 2005-08-31
JP2004532209A (ja) 2004-10-21
CA2442114A1 (en) 2002-10-10
PT1379239E (pt) 2007-12-06
WO2002078693A2 (en) 2002-10-10
IL157651A0 (en) 2004-03-28
IL157651A (en) 2010-02-17
DE60222396D1 (de) 2007-10-25
HRP20030771B1 (hr) 2008-10-31
KR100894189B1 (ko) 2009-04-22
NO20034289L (no) 2003-11-28
ZA200306795B (en) 2005-02-23
US20090306110A1 (en) 2009-12-10
DK1859798T3 (en) 2016-03-21
ES2566056T3 (es) 2016-04-08
CY1110362T1 (el) 2015-04-29
CN1610547A (zh) 2005-04-27
NO20034289D0 (no) 2003-09-25
AU2002303094B2 (en) 2006-11-23
EP1379239B1 (en) 2007-09-12
DE60222396T2 (de) 2008-05-15
CZ20032614A3 (en) 2004-03-17
HU230322B1 (hu) 2016-01-28
NO326160B1 (no) 2008-10-13
SK12052003A3 (sk) 2004-09-08
EA200301073A1 (ru) 2004-02-26
HUP0303651A3 (en) 2004-08-30
PT1859798E (pt) 2016-03-31
NZ527815A (en) 2005-05-27
ATE372768T1 (de) 2007-09-15
US8044090B2 (en) 2011-10-25
CZ305838B6 (cs) 2016-04-06
HK1061649A1 (en) 2004-09-30
ES2292758T3 (es) 2008-03-16
US20070099909A1 (en) 2007-05-03
KR20030090694A (ko) 2003-11-28
EA007493B1 (ru) 2006-10-27
IL185871A0 (en) 2008-01-06
US7157488B2 (en) 2007-01-02
CA2442114C (en) 2011-06-21
MXPA03008726A (es) 2003-12-12

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