SK287163B6 - Pyridazinylfenylhydrazón užitočný proti kongestívnemu zlyhaniu srdca a farmaceutická kompozícia s jeho obsahom - Google Patents

Pyridazinylfenylhydrazón užitočný proti kongestívnemu zlyhaniu srdca a farmaceutická kompozícia s jeho obsahom Download PDF

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Publication number
SK287163B6
SK287163B6 SK1288-2002A SK12882002A SK287163B6 SK 287163 B6 SK287163 B6 SK 287163B6 SK 12882002 A SK12882002 A SK 12882002A SK 287163 B6 SK287163 B6 SK 287163B6
Authority
SK
Slovakia
Prior art keywords
alkyl
methyl
phenyl
aryl
pyridazin
Prior art date
Application number
SK1288-2002A
Other languages
English (en)
Slovak (sk)
Other versions
SK12882002A3 (sk
Inventor
Jarmo Pystynen
Aino Pippuri
Anne Luiro
Pentti Nore
Reijo B�CKSTR�M
Kari L�NNBERG
Heimo Haikala
Jouko Levijoki
Petri Kaheinen
Juha Kaivola
Original Assignee
Orion Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Corporation filed Critical Orion Corporation
Publication of SK12882002A3 publication Critical patent/SK12882002A3/sk
Publication of SK287163B6 publication Critical patent/SK287163B6/sk

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/04Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SK1288-2002A 2000-03-13 2001-03-12 Pyridazinylfenylhydrazón užitočný proti kongestívnemu zlyhaniu srdca a farmaceutická kompozícia s jeho obsahom SK287163B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI20000577A FI20000577A0 (fi) 2000-03-13 2000-03-13 Pyridatsinyylifenyylihydratsoneja
PCT/FI2001/000241 WO2001068611A1 (en) 2000-03-13 2001-03-12 Pyridazinyl phenyl hydrazones useful against congestive heart failure

Publications (2)

Publication Number Publication Date
SK12882002A3 SK12882002A3 (sk) 2003-06-03
SK287163B6 true SK287163B6 (sk) 2010-02-08

Family

ID=8557913

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1288-2002A SK287163B6 (sk) 2000-03-13 2001-03-12 Pyridazinylfenylhydrazón užitočný proti kongestívnemu zlyhaniu srdca a farmaceutická kompozícia s jeho obsahom

Country Status (32)

Country Link
US (1) US6699868B2 (es)
EP (1) EP1265871B1 (es)
JP (1) JP2003527375A (es)
KR (1) KR20030001379A (es)
CN (1) CN1191241C (es)
AR (1) AR027644A1 (es)
AT (1) ATE317388T1 (es)
AU (2) AU4657701A (es)
BG (1) BG65859B1 (es)
BR (1) BR0109136A (es)
CA (1) CA2403188A1 (es)
CZ (1) CZ20022997A3 (es)
DE (1) DE60117131T2 (es)
DK (1) DK1265871T3 (es)
EA (1) EA005574B1 (es)
EE (1) EE200200520A (es)
ES (1) ES2256222T3 (es)
FI (1) FI20000577A0 (es)
HK (1) HK1052008A1 (es)
HR (1) HRP20020816A2 (es)
HU (1) HUP0300177A3 (es)
IL (2) IL151492A0 (es)
MX (1) MXPA02008997A (es)
NO (1) NO324172B1 (es)
NZ (1) NZ521162A (es)
PL (1) PL357107A1 (es)
RS (1) RS50439B (es)
SI (1) SI1265871T1 (es)
SK (1) SK287163B6 (es)
UA (1) UA74571C2 (es)
WO (1) WO2001068611A1 (es)
ZA (1) ZA200206917B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0015228D0 (en) * 2000-06-21 2000-08-16 Portela & Ca Sa Substituted nitrated catechols, their use in the treatment of some central and peripheral nervous system disorders
JP4561698B2 (ja) * 2002-02-19 2010-10-13 小野薬品工業株式会社 縮合ピリダジン誘導体化合物およびその化合物を有効成分として含有する薬剤
WO2004087641A1 (ja) * 2003-03-31 2004-10-14 Daiichi Pharmaceutical Co., Ltd. ヒドラゾン誘導体
GB0503962D0 (en) 2005-02-25 2005-04-06 Kudos Pharm Ltd Compounds
NZ574873A (en) 2006-07-25 2012-03-30 Cephalon Inc Pyridazinone derivatives as h3 inhibitors
US20100286150A1 (en) * 2007-01-17 2010-11-11 Fia Westerholm Levosimendan for use in treating chronic valvular disease
KR101954702B1 (ko) * 2011-09-27 2019-03-06 제온 코포레이션 중합성 화합물의 제조 중간체 및 그 제조 방법
EA034395B1 (ru) * 2013-01-18 2020-02-04 Бристол-Майерс Сквибб Компани Фталазиноны и изохинолиноны в качестве ингибиторов rock
JPWO2019235569A1 (ja) * 2018-06-08 2021-07-08 日産化学株式会社 キナーゼ阻害剤

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3531658A1 (de) 1985-09-05 1987-03-12 Boehringer Mannheim Gmbh Heterocyclisch substituierte indole, zwischenprodukte, verfahren zu ihrer herstellung und arzneimittel
GB8903130D0 (en) * 1989-02-11 1989-03-30 Orion Yhtymae Oy Substituted pyridazinones
US5185332A (en) * 1989-02-11 1993-02-09 Orion-Yhtyma Oy Thiadiazines and pharmaceutical compositions thereof as well as method of use
FI973804A (fi) * 1997-09-26 1999-03-27 Orion Yhtymae Oy Levosimendaanin oraalisia koostumuksia

Also Published As

Publication number Publication date
AR027644A1 (es) 2003-04-09
NO20024247L (no) 2002-10-25
US20030158200A1 (en) 2003-08-21
NO324172B1 (no) 2007-09-03
DK1265871T3 (da) 2006-06-06
MXPA02008997A (es) 2003-04-25
HUP0300177A3 (en) 2003-09-29
EA200200973A1 (ru) 2003-02-27
SK12882002A3 (sk) 2003-06-03
EP1265871B1 (en) 2006-02-08
EP1265871A1 (en) 2002-12-18
AU4657701A (en) 2001-09-24
YU68502A (sh) 2005-11-28
CN1191241C (zh) 2005-03-02
DE60117131D1 (de) 2006-04-20
ES2256222T3 (es) 2006-07-16
CN1418196A (zh) 2003-05-14
RS50439B (sr) 2009-12-31
EA005574B1 (ru) 2005-04-28
HK1052008A1 (en) 2003-08-29
BG65859B1 (bg) 2010-03-31
PL357107A1 (en) 2004-07-12
SI1265871T1 (sl) 2006-06-30
ZA200206917B (en) 2003-07-30
ATE317388T1 (de) 2006-02-15
NO20024247D0 (no) 2002-09-05
AU2001246577B2 (en) 2006-08-31
US6699868B2 (en) 2004-03-02
CZ20022997A3 (cs) 2003-04-16
KR20030001379A (ko) 2003-01-06
JP2003527375A (ja) 2003-09-16
BG107175A (bg) 2003-05-30
DE60117131T2 (de) 2006-10-26
FI20000577A0 (fi) 2000-03-13
WO2001068611A1 (en) 2001-09-20
IL151492A0 (en) 2003-04-10
NZ521162A (en) 2003-11-28
IL151492A (en) 2007-09-20
BR0109136A (pt) 2002-12-24
UA74571C2 (en) 2006-01-16
CA2403188A1 (en) 2001-09-20
HUP0300177A2 (hu) 2003-07-28
EE200200520A (et) 2004-04-15
HRP20020816A2 (en) 2004-12-31

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Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20110312