SK284864B6 - Použitie komplexu hyaluronátu zinku na prípravu farmaceutickej kompozície proti peptickým vredom - Google Patents
Použitie komplexu hyaluronátu zinku na prípravu farmaceutickej kompozície proti peptickým vredom Download PDFInfo
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- SK284864B6 SK284864B6 SK1468-99A SK146899A SK284864B6 SK 284864 B6 SK284864 B6 SK 284864B6 SK 146899 A SK146899 A SK 146899A SK 284864 B6 SK284864 B6 SK 284864B6
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- Prior art keywords
- zinc
- zinc hyaluronate
- hyaluronate
- gastric
- effect
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- CCGSUNCLSOWKJO-UHFFFAOYSA-N cimetidine Chemical compound N#CNC(=N/C)\NCCSCC1=NC=N[C]1C CCGSUNCLSOWKJO-UHFFFAOYSA-N 0.000 description 1
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- 239000010941 cobalt Substances 0.000 description 1
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- 229960001596 famotidine Drugs 0.000 description 1
- XUFQPHANEAPEMJ-UHFFFAOYSA-N famotidine Chemical compound NC(N)=NC1=NC(CSCCC(N)=NS(N)(=O)=O)=CS1 XUFQPHANEAPEMJ-UHFFFAOYSA-N 0.000 description 1
- 239000000417 fungicide Substances 0.000 description 1
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- LCLHHZYHLXDRQG-ZNKJPWOQSA-N pectic acid Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)O[C@H](C(O)=O)[C@@H]1OC1[C@H](O)[C@@H](O)[C@@H](OC2[C@@H]([C@@H](O)[C@@H](O)[C@H](O2)C(O)=O)O)[C@@H](C(O)=O)O1 LCLHHZYHLXDRQG-ZNKJPWOQSA-N 0.000 description 1
- 239000001814 pectin Substances 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU9700826A HU225991B1 (en) | 1997-04-29 | 1997-04-29 | Use of the zinc hyaluronate associate (complex) for the preparation of pharmaceutical compositions for oral use against peptic ulcer |
| PCT/HU1998/000044 WO1998048815A1 (en) | 1997-04-29 | 1998-04-28 | Use of zinc hyaluronate against peptic ulcer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SK146899A3 SK146899A3 (en) | 2000-06-12 |
| SK284864B6 true SK284864B6 (sk) | 2006-01-05 |
Family
ID=89995068
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK1468-99A SK284864B6 (sk) | 1997-04-29 | 1998-04-28 | Použitie komplexu hyaluronátu zinku na prípravu farmaceutickej kompozície proti peptickým vredom |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US6656921B1 (zh) |
| EP (1) | EP1017403B1 (zh) |
| JP (1) | JP2001522361A (zh) |
| KR (1) | KR100572190B1 (zh) |
| CN (1) | CN1126548C (zh) |
| AT (1) | ATE320814T1 (zh) |
| BG (1) | BG64458B1 (zh) |
| BR (1) | BR9809354A (zh) |
| CA (1) | CA2286756C (zh) |
| CZ (1) | CZ297317B6 (zh) |
| DE (1) | DE69833937T2 (zh) |
| DK (1) | DK1017403T3 (zh) |
| EA (1) | EA002134B1 (zh) |
| EE (1) | EE04953B1 (zh) |
| ES (1) | ES2259813T3 (zh) |
| HK (1) | HK1025250A1 (zh) |
| HU (1) | HU225991B1 (zh) |
| IL (1) | IL132214A0 (zh) |
| NO (1) | NO328313B1 (zh) |
| NZ (1) | NZ500978A (zh) |
| PL (1) | PL189526B1 (zh) |
| PT (1) | PT1017403E (zh) |
| SK (1) | SK284864B6 (zh) |
| TW (1) | TW501927B (zh) |
| UA (1) | UA62964C2 (zh) |
| WO (1) | WO1998048815A1 (zh) |
| ZA (1) | ZA983626B (zh) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU225991B1 (en) | 1997-04-29 | 2008-02-28 | Richter Gedeon Nyrt | Use of the zinc hyaluronate associate (complex) for the preparation of pharmaceutical compositions for oral use against peptic ulcer |
| ITPD980168A1 (it) * | 1998-07-06 | 2000-01-06 | Fidia Advanced Biopolymers Srl | Composizioni biocompatibili e biodegradabili comprendenti acido ialuronico e suoi derivati per il trattamento delle ulcere dell'appara |
| HUP0303779A2 (en) * | 2003-11-20 | 2006-02-28 | Richter Gedeon Vegyeszet | Pharmaceutical compositions containing hyaluronan complex for the treatment of sclerosis multiplex |
| AU2006287321B2 (en) * | 2005-09-09 | 2011-09-29 | Bally Gaming, Inc. | Wagering game system with community gaming system |
| CN100355790C (zh) * | 2005-11-04 | 2007-12-19 | 山东福瑞达生物化工有限公司 | 一种透明质酸锌的制备方法 |
| CN100348621C (zh) * | 2005-12-02 | 2007-11-14 | 凌沛学 | 透明质酸铋及其制备方法和应用 |
| CN1329414C (zh) * | 2005-12-02 | 2007-08-01 | 凌沛学 | 透明质酸铋钾及其制备方法和应用 |
| CN101023961B (zh) * | 2006-02-23 | 2010-07-21 | 山东省生物药物研究院 | 一种含透明质酸钠和锌盐的药物组合物 |
| ITMI20061132A1 (it) * | 2006-06-13 | 2007-12-14 | Sinclair Pharmaceuticals Ltd | Composizioni topiche antimicrobiche comprendenti lattoferrina, acido ialuronico o suoi sali ed estratti vegetali |
| TWI516269B (zh) * | 2009-08-14 | 2016-01-11 | 禾伸堂生技股份有限公司 | 使用於炎症性腸疾病（ｉｂｄ）治療和預防之透明質酸混合物 |
| TWI383796B (zh) * | 2009-08-14 | 2013-02-01 | Holy Stone Healthcare Co Ltd | Use of hyaluronic acid mixture for the treatment and prevention of peptic ulcer and duodenal ulcer |
| HUP0900717A3 (en) * | 2009-11-18 | 2012-02-28 | Richter Gedeon Nyrt | Pharmaceutical composition for urological use containing zinc hyaluronate |
| US20110166099A1 (en) * | 2010-01-04 | 2011-07-07 | Wu Tsung-Chung | Mixture of hyaluronic acid for treating and preventing peptic ulcer and duodenal ulcer |
| US8722644B2 (en) | 2010-01-04 | 2014-05-13 | Holy Stone Healthcare Co., Ltd. | Mixture of hyaluronic acid for treating and preventing peptic ulcer and duodenal ulcer |
| ES2388281B1 (es) * | 2010-12-27 | 2013-10-01 | Laboratorios Viñas S.A. | Composición farmacéutica que comprende ácido hialurónico y un compuesto de zinc y pastilla con palito y procedimiento para preparación correspondientes |
| US20150209384A1 (en) * | 2012-03-01 | 2015-07-30 | Kewpie Corporation | Oral preparation for promoting expression of tgf-beta, oral preparation for inhibiting production of pain-mediating substance, and oral preparation for preventing edema |
| JPWO2015076294A1 (ja) * | 2013-11-22 | 2017-03-16 | キユーピー株式会社 | 薬剤の副作用である胃潰瘍の発症抑制方法、および胃潰瘍発症が抑制された経口薬剤組成物ならびにその製造方法 |
| CN104262499A (zh) * | 2014-09-03 | 2015-01-07 | 佐源集团有限公司 | 一种低聚果糖锌及含有低聚果糖锌的口服液 |
| CN108051553A (zh) * | 2017-12-29 | 2018-05-18 | 武汉轻工大学 | 一种仔猪肠道功能保护剂的筛选方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1229075B (it) * | 1985-04-05 | 1991-07-17 | Fidia Farmaceutici | Medicamenti per uso topico, ottenuti tramite l'impiego dell'acido ialuronico |
| EP0259485A4 (en) * | 1986-03-14 | 1988-07-29 | Bio Technology General Corp | HEAVY METAL SALTS OF HYALURONIC ACID FOR USE AS AN ANTIMICROBIAL AGENT. |
| US5472950A (en) | 1989-02-24 | 1995-12-05 | Richter Gedeon Vegyeszeti Gyar Rt. | Compositions containing cobalt hyaluronic acid complex |
| HU203372B (en) | 1989-02-24 | 1991-07-29 | Richter Gedeon Vegyeszet | Process for producing hyaluronic associates and pharmaceutical compositions and cosmetics comprising such active ingredient |
| US6458774B1 (en) * | 1989-02-24 | 2002-10-01 | Richter Gedeon Vegyeszeti Gyar Rt. | Compositions containing hyaluronic acid associates and a process for preparing same |
| JPH0648950A (ja) * | 1992-07-30 | 1994-02-22 | Taito Kk | 抗潰瘍剤 |
| HU225329B1 (en) * | 1996-09-12 | 2006-09-28 | Richter Gedeon Vegyeszet | Use of zinc or cobalt hyaluronate associate for the manufacture of pharmaceutical compositions of antimicrobial activity |
| HU225991B1 (en) | 1997-04-29 | 2008-02-28 | Richter Gedeon Nyrt | Use of the zinc hyaluronate associate (complex) for the preparation of pharmaceutical compositions for oral use against peptic ulcer |
-
1997
- 1997-04-29 HU HU9700826A patent/HU225991B1/hu unknown
-
1998
- 1998-04-28 EP EP98920684A patent/EP1017403B1/en not_active Expired - Lifetime
- 1998-04-28 SK SK1468-99A patent/SK284864B6/sk not_active IP Right Cessation
- 1998-04-28 PL PL98336482A patent/PL189526B1/pl unknown
- 1998-04-28 WO PCT/HU1998/000044 patent/WO1998048815A1/en active IP Right Grant
- 1998-04-28 BR BR9809354-1A patent/BR9809354A/pt not_active IP Right Cessation
- 1998-04-28 EA EA199900983A patent/EA002134B1/ru not_active IP Right Cessation
- 1998-04-28 NZ NZ500978A patent/NZ500978A/en not_active IP Right Cessation
- 1998-04-28 DK DK98920684T patent/DK1017403T3/da active
- 1998-04-28 UA UA99116468A patent/UA62964C2/uk unknown
- 1998-04-28 IL IL13221498A patent/IL132214A0/xx not_active IP Right Cessation
- 1998-04-28 CN CN98804672A patent/CN1126548C/zh not_active Expired - Fee Related
- 1998-04-28 CA CA002286756A patent/CA2286756C/en not_active Expired - Fee Related
- 1998-04-28 AT AT98920684T patent/ATE320814T1/de active
- 1998-04-28 CZ CZ0382799A patent/CZ297317B6/cs not_active IP Right Cessation
- 1998-04-28 TW TW087106525A patent/TW501927B/zh not_active IP Right Cessation
- 1998-04-28 PT PT98920684T patent/PT1017403E/pt unknown
- 1998-04-28 US US09/403,714 patent/US6656921B1/en not_active Expired - Lifetime
- 1998-04-28 JP JP54638898A patent/JP2001522361A/ja active Pending
- 1998-04-28 ES ES98920684T patent/ES2259813T3/es not_active Expired - Lifetime
- 1998-04-28 DE DE69833937T patent/DE69833937T2/de not_active Expired - Lifetime
- 1998-04-28 KR KR1019997010037A patent/KR100572190B1/ko not_active IP Right Cessation
- 1998-04-28 EE EEP199900470A patent/EE04953B1/xx unknown
- 1998-04-29 ZA ZA983626A patent/ZA983626B/xx unknown
-
1999
- 1999-10-19 BG BG103822A patent/BG64458B1/bg unknown
- 1999-10-26 NO NO19995229A patent/NO328313B1/no not_active IP Right Cessation
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2000
- 2000-07-20 HK HK00104494A patent/HK1025250A1/xx not_active IP Right Cessation
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| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Patent lapsed due to non-payment of maintenance fees |
Effective date: 20170428 |