SK283944B6 - Potiahnuté častice na báze granulovaných mikrokryštálov ibuprofénu a spôsob ich prípravy - Google Patents
Potiahnuté častice na báze granulovaných mikrokryštálov ibuprofénu a spôsob ich prípravy Download PDFInfo
- Publication number
- SK283944B6 SK283944B6 SK566-2001A SK5662001A SK283944B6 SK 283944 B6 SK283944 B6 SK 283944B6 SK 5662001 A SK5662001 A SK 5662001A SK 283944 B6 SK283944 B6 SK 283944B6
- Authority
- SK
- Slovakia
- Prior art keywords
- ibuprofen
- ethylcellulose
- respect
- particles
- coating
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/501—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Developing Agents For Electrophotography (AREA)
- Glanulating (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9814033A FR2785539B1 (fr) | 1998-11-06 | 1998-11-06 | Particules enrobees d'ibuprofene cristallin granule |
PCT/FR1999/002682 WO2000027368A1 (fr) | 1998-11-06 | 1999-11-03 | Particules enrobees d'ibuprofene cristallin granule |
Publications (2)
Publication Number | Publication Date |
---|---|
SK5662001A3 SK5662001A3 (en) | 2001-11-06 |
SK283944B6 true SK283944B6 (sk) | 2004-05-04 |
Family
ID=9532492
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SK566-2001A SK283944B6 (sk) | 1998-11-06 | 1999-11-03 | Potiahnuté častice na báze granulovaných mikrokryštálov ibuprofénu a spôsob ich prípravy |
Country Status (26)
Country | Link |
---|---|
US (1) | US6951657B1 (de) |
EP (1) | EP1126829B1 (de) |
JP (1) | JP3987282B2 (de) |
KR (1) | KR100586059B1 (de) |
CN (1) | CN1154482C (de) |
AT (1) | ATE265206T1 (de) |
AU (1) | AU765765B2 (de) |
BR (1) | BR9915111A (de) |
CA (1) | CA2349503C (de) |
CZ (1) | CZ292290B6 (de) |
DE (1) | DE69916876T2 (de) |
DK (1) | DK1126829T3 (de) |
EA (1) | EA002897B1 (de) |
ES (1) | ES2219073T3 (de) |
FR (1) | FR2785539B1 (de) |
HK (1) | HK1039890B (de) |
HU (1) | HU229936B1 (de) |
IL (1) | IL142787A (de) |
MX (1) | MXPA01004517A (de) |
NZ (1) | NZ511479A (de) |
PL (1) | PL194527B1 (de) |
PT (1) | PT1126829E (de) |
SK (1) | SK283944B6 (de) |
TR (1) | TR200101230T2 (de) |
WO (1) | WO2000027368A1 (de) |
ZA (1) | ZA200103630B (de) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2795962B1 (fr) | 1999-07-08 | 2003-05-09 | Prographarm Laboratoires | Procede de fabrication de granules enrobes a gout masque et liberation immediate du principe actif |
FR2824477B1 (fr) * | 2001-05-09 | 2005-09-09 | Ethypharm Lab Prod Ethiques | Granules enrobes a base d'inhibiteur de l'enzyme de conversion de l'anfiotensine, leur procede de preparation et comprimes orodispersibles contenant les granules enrobes |
FR2850275B1 (fr) * | 2003-01-24 | 2005-04-08 | Scherer Technologies Inc R P | Capsules molles a macher contenant une substance active a gout masque |
EP1800667A1 (de) | 2005-12-23 | 2007-06-27 | Losan Pharma GmbH | Schnell lösliches Ibuprofen-Granulat |
AU2006226293B2 (en) * | 2005-03-22 | 2011-04-07 | Losan Pharma Gmbh | Solubilized ibuprofen |
US8067451B2 (en) * | 2006-07-18 | 2011-11-29 | Horizon Pharma Usa, Inc. | Methods and medicaments for administration of ibuprofen |
EP1919288A4 (de) * | 2005-07-18 | 2009-12-16 | Horizon Therapeutics Inc | Famotidin- und ibuprofenhaltige arzneimittel und ihre verabreichung |
US20080020040A1 (en) * | 2006-07-18 | 2008-01-24 | Horizon Therapeutics, Inc. | Unit dose form for administration of ibuprofen |
DE102005049001A1 (de) * | 2005-10-11 | 2007-04-12 | Basf Ag | Verfahren zur Herstellung von direkttablettierbaren Ibuprofen-Formulierungen |
US8067033B2 (en) | 2007-11-30 | 2011-11-29 | Horizon Pharma Usa, Inc. | Stable compositions of famotidine and ibuprofen |
ATE553755T1 (de) * | 2006-07-27 | 2012-05-15 | Univ Sunderland | Stärke enthaltende beschichtungszusammensetzung |
TWI564008B (zh) | 2010-09-30 | 2017-01-01 | 鹽野義製藥股份有限公司 | 難溶性藥物之溶解性改善製劑 |
WO2014198999A1 (en) * | 2013-06-13 | 2014-12-18 | Opes Corporation Oy | Matrix |
US9474699B2 (en) * | 2014-03-31 | 2016-10-25 | Johnson & Johnson Consumer Inc. | Compostions and methods for enhancing the topical application of a basic benefit agent |
WO2016081783A1 (en) * | 2014-11-19 | 2016-05-26 | Kiromic, Llc | Novel nanoparticle-based vaccine targeting cancer/testis antigens (cta) and its use in solid and hematological malignancies |
WO2019080693A1 (zh) | 2017-10-26 | 2019-05-02 | 浙江越甲药业有限公司 | 一种稳定的含有非甾体抗炎药衍生物的药物组合物 |
AU2020225818A1 (en) | 2019-02-22 | 2021-10-14 | Catalent U.K. Swindon Zydis Limited | Preserving functionally-coated API particles produced by solventless mixing processes in aqueous suspension |
GB2597577B (en) | 2019-02-22 | 2023-09-20 | Catalent Uk Swindon Zydis Ltd | Minimizing agglomeration, aeration, and preserving the coating of pharmaceutical compositions comprising ibuprofen |
CN113453662A (zh) * | 2019-02-22 | 2021-09-28 | 康特伦英国斯温顿捷迪斯有限公司 | 储存期间药物颗粒包衣材料的团聚最小化以稳定化药物产品的崩解时间 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4308251A (en) * | 1980-01-11 | 1981-12-29 | Boots Pharmaceuticals, Inc. | Controlled release formulations of orally-active medicaments |
US4588612A (en) * | 1985-04-24 | 1986-05-13 | Scm Corporation | Pretreatment in encapsulation process |
GB8519310D0 (en) * | 1985-07-31 | 1985-09-04 | Zyma Sa | Granular active substances |
US4835186A (en) | 1987-06-15 | 1989-05-30 | American Home Products Corporation | Spray dried ibuprofen |
US4835187A (en) * | 1987-06-15 | 1989-05-30 | American Home Products Corporation | Spray dried ibuprofen |
US5084278A (en) * | 1989-06-02 | 1992-01-28 | Nortec Development Associates, Inc. | Taste-masked pharmaceutical compositions |
NZ234587A (en) * | 1989-08-04 | 1991-11-26 | Mcneil Ppc Inc | A chewable pharmaceutical tablet of compressed coated granules |
IT1241417B (it) * | 1990-03-06 | 1994-01-14 | Vectorpharma Int | Composizioni terapeutiche a rilascio controllato di farmaci supportatisu polimeri reticolati e rivestiti con film polimerici,e loro processodi preparazione |
CA2076983A1 (en) * | 1990-04-11 | 1991-10-12 | Robert Wu-Wei Shen | Taste masking of ibuprofen by fluid bed coating |
FR2679451B1 (fr) * | 1991-07-22 | 1994-09-09 | Prographarm Laboratoires | Comprime multiparticulaire a delitement rapide. |
US5191114A (en) * | 1991-10-09 | 1993-03-02 | Sage Pharmaceuticals, Inc. | Process for enhancing the flow characteristics of ibuprofen |
ZA945944B (en) * | 1993-08-13 | 1996-02-08 | Eurand America Inc | Procedure for encapsulating nsaids |
US5567439A (en) * | 1994-06-14 | 1996-10-22 | Fuisz Technologies Ltd. | Delivery of controlled-release systems(s) |
-
1998
- 1998-11-06 FR FR9814033A patent/FR2785539B1/fr not_active Expired - Lifetime
-
1999
- 1999-11-03 WO PCT/FR1999/002682 patent/WO2000027368A1/fr active IP Right Grant
- 1999-11-03 EP EP99954047A patent/EP1126829B1/de not_active Expired - Lifetime
- 1999-11-03 US US09/830,101 patent/US6951657B1/en not_active Expired - Lifetime
- 1999-11-03 BR BR9915111-1A patent/BR9915111A/pt not_active Application Discontinuation
- 1999-11-03 DK DK99954047T patent/DK1126829T3/da active
- 1999-11-03 PT PT99954047T patent/PT1126829E/pt unknown
- 1999-11-03 PL PL99347549A patent/PL194527B1/pl unknown
- 1999-11-03 MX MXPA01004517A patent/MXPA01004517A/es active IP Right Grant
- 1999-11-03 ES ES99954047T patent/ES2219073T3/es not_active Expired - Lifetime
- 1999-11-03 NZ NZ511479A patent/NZ511479A/xx not_active IP Right Cessation
- 1999-11-03 TR TR2001/01230T patent/TR200101230T2/xx unknown
- 1999-11-03 AT AT99954047T patent/ATE265206T1/de active
- 1999-11-03 HU HU0104394A patent/HU229936B1/hu unknown
- 1999-11-03 CN CNB998138002A patent/CN1154482C/zh not_active Expired - Lifetime
- 1999-11-03 KR KR1020017005749A patent/KR100586059B1/ko not_active IP Right Cessation
- 1999-11-03 SK SK566-2001A patent/SK283944B6/sk not_active IP Right Cessation
- 1999-11-03 DE DE69916876T patent/DE69916876T2/de not_active Expired - Lifetime
- 1999-11-03 AU AU10508/00A patent/AU765765B2/en not_active Expired
- 1999-11-03 EA EA200100491A patent/EA002897B1/ru not_active IP Right Cessation
- 1999-11-03 CA CA2349503A patent/CA2349503C/fr not_active Expired - Fee Related
- 1999-11-03 JP JP2000580599A patent/JP3987282B2/ja not_active Expired - Lifetime
- 1999-11-03 CZ CZ20011434A patent/CZ292290B6/cs not_active IP Right Cessation
-
2001
- 2001-04-25 IL IL142787A patent/IL142787A/en not_active IP Right Cessation
- 2001-05-04 ZA ZA200103630A patent/ZA200103630B/en unknown
-
2002
- 2002-02-01 HK HK02100786.6A patent/HK1039890B/zh not_active IP Right Cessation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SK283944B6 (sk) | Potiahnuté častice na báze granulovaných mikrokryštálov ibuprofénu a spôsob ich prípravy | |
KR100767928B1 (ko) | 활성 성분의 맛이 차폐되고 활성 성분이 즉시 방출되는 코팅된 과립의 제조 방법 | |
US4840799A (en) | Process for preparing rapidly disintegrating granulates | |
SK6962002A3 (en) | A process for the coating of tablet cores and tablets obtained by this process | |
JP2003531099A (ja) | 改良された水溶解度をもつ医薬製剤 | |
PL173676B1 (pl) | Sposób wytwarzania nowego preparatu farmaceutycznego w postaci tabletki musującej i/lub rozpadającej się albo w postaci granulatu szybko rozpuszczalnego | |
SK284811B6 (sk) | Farmaceutická formulácia a spôsob jej výroby | |
JP2002523443A (ja) | オメプラゾール製剤 | |
PL186386B1 (pl) | Sposób wytwarzania granulatu zawierającego aktywny przy podawaniu drogą doustną antybiotyk beta-laktamowy oraz sposób wytwarzania szybko rozpadającejsię postaci dawkowania zawierającej aktywny przy podawaniu drogą doustną antybiotyk beta-laktamowy | |
JP4465152B2 (ja) | 味をマスキングした、顆粒及びコーティングされた顆粒剤 | |
RU97111870A (ru) | Фармацевтический состав, содержащий ламотригин | |
SK18142001A3 (sk) | Matricová zmes s maskovanou chuťou a spôsob jej výroby | |
AU2012369903A1 (en) | Pharmaceutical formulation having improved stability | |
JPH0691150A (ja) | マスクされた粒状物 | |
WO2003070223A1 (fr) | Preparations a liberation lente et methode de production desdites preparations | |
SK164696A3 (en) | Carbamazepine medicament with retarded active substance release | |
SK287281B6 (sk) | Viacdávková farmaceutická kompozícia v tuhej perorálnej forme s riadeným uvoľňovaním a spôsob jej prípravy | |
JP2006306766A (ja) | テオフィリン徐放性微粒子製剤及びその製造方法 | |
JP2008184393A (ja) | アクリルコポリマーとの混合粉砕による難水溶性薬物の溶解性改善及び放出制御型粒子の調製 | |
KR100759607B1 (ko) | 세푸록심 악세틸 과립 및 이의 제조방법 | |
AU2004233606A1 (en) | Pellet formulations of acid-labile antiulcer benzimidazole compounds | |
KR100839283B1 (ko) | 암로디핀 및 그 염을 함유한 필름코팅 제제 | |
KR20090005485A (ko) | 세푸록심 악세틸 함유 과립 및 그의 제조방법 | |
WO2001076607A1 (fr) | Sirop sous forme de substance seche renfermant des microcapsules de theophylline a liberation prolongee | |
JP2006117577A (ja) | テオフィリン含有徐放性製剤 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK4A | Patent expired |
Expiry date: 20191103 |